Corporate Banner
Satellite Banner
Technology Networks Header
Friday, April 18, 2014
 
Register | Sign in
Mapping Chemical Gradients in Living Tis...
TR40 - small,portable temperature contro...LabTube Meets Jonathan Harkins, Integra ...Vertex Pipette Tips...

Featured Products
Featured ProductXiril Liquid Handling Workstation Neon 100 company logo
Xiril Liquid Handling Workstation Neon 100
Featured ProductGreenScreen HC company logo
GreenScreen HC

Webcasts
Worried about your cell-based assays? Remote monitoring with CNS offers complete peace of mind!Worried about your cell-based assays? Remote monitoring with CNS offers complete peace of mind!
Michael Fejtl, Market Manager, Tecan Austria
Challenges of Implementing and Validating CTC Assays in Oncology Clinical TrialsChallenges of Implementing and Validating CTC Assays in Oncology Clinical Trials
Iman Jilani, Pfizer, speaking at Exosomes and Circulating Biomarkers Summit 2013.

Market Reports
Flow Chemistry Market by Reactor Type, Application & Geography - Trends & Forecast to 2018
MarketsandMarkets

This report Flow Chemistry Market is segmented by type of reactor with major focus on micro reactor systems. The micro reactor system market is further segmented by type along with geography and applications.
Facial Recognition Market: Global Advancements, Emerging Applications, Business Models and Worldwide Market Forecasts and Analysis (2013 ? 2018)
MarketsandMarkets

The report is focused to give a birds eye-view of the complete facial recognition industry with regards to technology and solutions, software, hardware and services. It also provides revenue distribution of the market based on various industry vertical or end-users.
Biomarkers Market 2013 - 2020
Allied Market Research

Disease diagnostic application remains the key area of application that is expected to reach 6.1 $billion in 2020. However, application of diagnostic biomarkers in forensics and molecular diagnostics is catching up quite significantly. Molecular diagnostics is expected to grow at a CAGR of 17.6% from 2013 to 2020.
Mass Spectrometry for Clinical Diagnostics Applications 2013 Focus Report
SELECTBIO

This report from SELECTBIO addresses a number of topics including, market segmentation, market landscape, and mass spectrometry products currently on the market as well as in development.
Liposomes
RI Technologies

This market insight report on liposomes gives an insight into global liposomes market. The report provides market analytics by application, and by therapeutic area.
Stem Cell Research
Stem Cell Research

This report on Stem Cell Research gives a market insight into the ever progressing and debatable market of Stem Cell Research segmented by type, technology and therapeutic area.
Stem Cell Research in Cardiology
RI Technologies

The report serves as a guide to global market for stem cells in cardiology covering more than 230 companies that are engaged in stem cell R&D, storage, banking, discovery, testing and supply of products and services.
Security Technologies in Biotechnology
RI Technologies

The report serves as a guide to security technology industry for biotechnology applications, covering more than 350 companies that are engaged in security technology/products and services.
RNAi
RI Technologies

The report serves as a guide to global RNAi industry covering 280 plus companies that are engaged in RNAi synthesis, R&D, therapeutics, test kits, tools and services.
Polylactic Acid
RI Technologies

This market insight report provides market analytics by form, and by application. The market is divided by form into films & sheets, coatings, fibers and other; and by Application into food, textile, medical, and other.
Scroll Up
Scroll Down
Scientific News
Gene Linked to Excess Male Hormones in Female Infertility Disorder
Discovery by NIH-supported researchers may lead to diagnostic test, treatment.
How a Silly Putty Ingredient Could Advance Stem Cell Therapies
The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become.
Domainex Programme Shows Great Promise for the Treatment of Inflammatory Diseases
Company’s IKKe/TBK1 programme to offer a disease-modifying treatment for COPD patients.
Nanocrystalline Cellulose Modified into an Efficient Viral Inhibitor
Researchers have succeeded in creating a surface on nano-sized cellulose crystals that imitates a biological structure.
Drug Does Not Improve Set of Cardiovascular Outcomes for Diastolic Heart Failure
NIH-supported study finds drug does appear to reduce hospitalizations for diastolic heart failure.
Will Forensic Biology Become Forensic Molecular Biology?
The article presents some examples of the potential for new molecular biology technologies to assist in the investigation of crime.
Lab Scale Manufacturing Using Continuous Crystallization
A new METTLER TOLEDO On-demand webinar explores recent research that could revolutionize pharmaceutical production.
Unexpected Protein Partnership has Implications for Cancer Treatment
Scientists have identified a macrophage that works together in response to cancer drugs to increase inflammation in a way that may alter tumor growth.
Targeting Cancer with a Triple Threat
MIT chemists design nanoparticles that can deliver three cancer drugs at a time.
Fluorescent Sensor Detects Date Rape Drug Within Seconds
The sensor, developed by researchers from the National University of Singapore (NUS), identifies the presence of GHB, a drug known commonly used to spike beverages.
Scroll Up
Scroll Down
Business News
Pittcon 2014 Informatics Wrap-Up
Applications focus on better, faster, cheaper data management in the lab
Dicerna Initiates Phase 1 Study of DCR-MYC in Patients with Solid Tumors
DCR-MYC is the first Dicer Substrate RNA interference candidate to advance into clinical testing.
Aesica Successfully Introduces Serialization Services at Italian Site
Initiates commercial production of two product lines for the Chinese market.
WuXi PharmaTech Announces Management Appointments
Dr. Steve Yang joins Company as EVP and chief operating officer and Edward Hu named chief investment officer and remains chief financial officer.
4SC Discovery Receives EU Grant Worth EUR 450,000
Three-year research collaboration with the Medical Clinic of the University of Munich includes a project for identification and optimization of new compounds against a novel epigenetic target molecule.
Nanobiotix Appoints Thierry Otin as Head of Manufacturing and Supply
Mr Otin will be responsible for the manufacturing plans to move NBTXR3 from clinical trials.
Dosing Initiated in Phase I/II Clinical Trial of APR-246 in Ovarian Cancer
Promising data from trial has been presented in Journal of Clinical Oncology.
Critical Pharmaceuticals Receives Notice of Allowance from USPTO
CriticalSorb™ formulation technology covered by this patent has exceptional utility for the delivery of poorly absorbed biological and small molecule drugs.
UK to Invest up to £2.8M in Bioscience Research
The investment in collaborative feasibility studies aims to stimulate innovation across four technology areas that will enable and underpin UK growth.
Global Molecular Spectroscopy Market 2014-2018
Owing to the diverse nature of molecular spectroscopy technologies, these technologies cover a wide area of applications.
Scroll Up
Scroll Down

Events
Clinical Translation of Stem C
21 Apr 2014
Clinical Translation of Stem C ...
Fragment-Based Drug Discovery 
19 Jul 2014
Fragment-Based Drug Discovery  ...
Clinical Trial Billing Bootcam
22 Apr 2014
Clinical Trial Billing Bootcam ...
Digital Marketing for Medical
22 Apr 2014
Digital Marketing for Medical ...

ePosters
High-throughput analysis of protein formulations by DLS
Wyatt Technology Corporation

High-throughput analysis of protein formulations by Dynamic Light Scattering (DLS): thermal stability, colloidal stability and a thermal anomaly in the colloidal stability parameter D1
GC-MS Comparison of Lavindin Grosso Oil Obtained by Steam Distillation and SFE
Miami University Middletown

Oil was extracted from Lavindin Grosso using steam distillation and using supercritical fluid extraction (SFE). Multiple analyses of the same extract demonstrated repeatability of the analytical method. The variability between batches of distillate bracketed the composition obtained by SFE. The differences among the oils could be attributed more to where the lavender was grown than to the extraction method.
Digital microphotographic atlas of the adult zebrafish cerebellum
Wagner College

Sagittal, coronal and horizontal, one micron thick plastic (semithin) sections of adult zebrafish (Danio rerio) brain were photographed in 40X. The sections were then photomontaged together using in Adobe Photoshop CS5 Extended Version 12.0 to make the photographic atlas.
Targeted cancer therapy based on blocking the expression of genes and small doses of oxaliplatin.
Centre for Medical Genetics Russian Academy of Medical Sciences, Koltsov Institute of Developmental Biology Russian Academy of Sciences

The major drawbacks of the prescribed chemotherapy, are still remain the significant side effects and drug - resistance. Even targeted chemotherapy by means of specific antibodies do not always help to solve these complications. Our purpose was to identify potential biological targets associated with the development of drug resistance and to develop a specific method of suppressing the viability of cancer cells exposed to low doses of standard chemotherapy.
A multianalyte algorithm PCR-based blood test outperforms single analyte ELISA-based blood tests for neuroendocrine tumor detection
Wren Laboratories

In a prospective study, in age-/sex- and ethnicity-matched patients and controls (n=82), a 51 panel multigene blood transcript test (NETest) was identified to be significantly more sensitive and accurate (>93%) than any single analyte assay (Chromogranin A, Pancreastatin or Neurokinin A) for neuroendocrine tumor detection.
Droplet Microfluidics for 3D Epithelial Cell Culture
CEA Grenoble

The challenge facing 3D cell culture today is to adapt current models to a systems biology approach - in particular, to enable RNA interference-based screens to study the effects of the microenvironment on cellular function.
New Sorbent from Agro-industrial Waste and its Potential Use in 17ß-Estradiol and 17α-Ethynylestradiol Removal
Federal University of Rio Grande do Sul

In recent years, the increasing introduction of new chemicals in the market, and the development of more accurate analytical methods, added a variety of endocrine disruptors compounds (EDC). Even though they are found in very low concentrations (range of ng L-1) there is still a lack of knowledge about long-term risks of EDC for non-target organisms as well as for human health.
Isolation, Identification, and Determination of Designer Anabolic Steroids Commonly Found in Dietary Supplements
U.S. Food and Drug Administration, Forensic Chemistry Center

A general analytical approach in identifying emerging steroid-like compounds is presented, including analysis by GC-MS, LC-MS, and/or HPLC-UV. Isolation of unknown compounds was achieved by high performance liquid chromatography with fraction collection. Isolated compounds were characterized by Nuclear Magnetic Resonance spectroscopy and high resolution accurate mass-mass spectrometry to elucidate their structure.
Purification of Synthetic Oligodeoxynucleotides via Catching by Polymerization
Michigan Technological University

This poster describes new simple methods for oligodeoxynucleotide purification without chromotography.
Microfluidic chips with microscale traps for cancer cells study by confocal laser scanning microscopy
ITMO University

In this work, microfluidic chip with integrated microscale hydrodynamic traps for fixation of cancer cells in native state to study by confocal laser scanning microscopy in the chip’s chamber was designed, fabricated and tested.
Scroll Up
Scroll Down
Application Notes
Performing ADCC Reporter Bioassay with an Environmentally Controlled Microplate Reader
Tecan Group Ltd.

The Promega ADCC Reporter Bioassay provides effector and target cells in frozen, thaw-and-use format, removing the need for isolating or culturing cells in order to perform the assay. Reporter induction requires a six-hour to overnight incubation in a standard cell culture incubator. The CO2 and temperature control features of the Tecan Infinite® 200 PRO with GCM allow the assay induction to be performed without the requirement for a cell culture incubator.
Tecan AC Extraction Plate™
Tecan Group Ltd.

A growing number of laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) for the determination of vitamin D. The advantage of the latter method is unparalleled specificity combined with high sensitivity, offering the potential for the determination of multiple analytes, such as 25OH-vitamin D3 and 25OH-vitamin D2.
Tecan AC Extraction Plate™
Tecan Group Ltd.

There is an increasing demand for the determination of Vitamin D status which is based on the quantification of the two metabolites 25-OH-Vitamin D3/D2. Numerous laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) because of its specificity combined with high sensitivity. Moreover LC-MS/MS offers the potential for multianalyte determination which is required for Vitamin D status determination.
Tecan AC Extraction Plate™
Tecan Group Ltd.

THC , the main active compound in marijuana, is metabolized to ?9-(11-OH)-tetrahydrocannabinol (11-OH-THC) and 11-nor-?9-carboxy-tetrahydrocannabinol (THC-COOH). Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Tecan AC Extraction Plate™
Tecan Group Ltd.

Testosterone is a powerful androgen that is primarily secreted by Leydig cells in men and theca cells in women. For accurate, reproducible quantification of testosterone, a growing number of laboratories is shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS). This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.
Creating dose-response curves for cell-based and biochemical assays with the HP D300 Digital Dispenser
Tecan Group Ltd.

Small molecule drug discovery relies on the evaluation of one compound against another compound. Measurement of the activity of the small molecule against a target must be standardized by determining the IC50 or EC50 value using does response curve. The classical method of generating a dose-response curve is via serial dilution; however this approach has a number of drawbacks. Today, there is an alternative solution which eliminates these limitations: the HP D300 Digital Dispenser.
Tag-lite® two-cell assay: a valuable tool for protein drug discovery
Tecan Group Ltd.

Antibodies are central mediators of the immune system, IgG being the most dominant. Binding of IgG/antigen complexes to membrane-bound Fc? receptors triggers a cellular immune response. Alterations in the Fc portion of the antibody by introducing mutations can lead to complete abolition of Fc? receptor binding. This describes the development of a cellbased TR-FRET assay to determine the simultaneous binding of an antibody to its antigen and huFc?RIIIa present on different cells.
Transcreener® ADP2 TR-FRET Red Assay
Tecan Group Ltd.

Adenosine diphosphate (ADP) is an important mediator of cellular metabolism that is essential for maintaining energy levels. The Transcreener ADP2 TR-FRET Red Assay is intended for the detection of ADP production by any kinase or ATPase, and has been developed specifically for high throughput screening applications.
3D Cell Culture: mimicking real tissue
Tecan Group Ltd.

Technological advances in the last couple of years have enabled 3D scaffolds to be engineered that offer a real proxy for the in vivo environment which can be easily and routinely used in a cell culture laboratory. Alvetex Scaffold enables cells to develop natural, in vivo-like intercellular interactions, providing an ideal environment for real three-dimensional growth and nutrient exchange that is comparable to intra-capillary exchange in living tissues.
Colony Picking - fully automated screening of fungi
Tecan Group Ltd.

Manual screening processes are very costly and time consuming. This ambitious project for high throughput screening (HTS) of cellulase-producing fungal strains demonstrates the high capacity and unique features of the Freedom EVO colony picking workstation. The picking of fungi is more complex than for typical bacterial colonies, and requires advanced selection criteria to be combined with complex pipetting and a tip movement that mimics the manual picking process.
Scroll Up
Scroll Down
Skyscraper Banner
Skyscraper Banner
Follow TechNetcom1 on Twitter
Technology Networks Ltd. on LinkedIn
Go to LabTube.tv