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Webcasts
Modifying Cell Lines for Target Discovery and ValidationModifying Cell Lines for Target Discovery and Validation
In this 30-minute seminar, we will discuss the process of genome editing, address factors affecting the design of a genome editing project, and explore the application of modified cell lines for target discovery and validation.
Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!
In this webinar, solutions will be presented for fast DNA quantification, single cell counting and viability analysis, and automating long-term live kinetic cell assays.

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
High Throughput Screening (HTS) Market by Technology, Applications, and End Users - Forecast to 2018
MarketsandMarkets

Technological advancements and flourishing outsourcing industry likely to propel the growth of the global high throughput screening market. In this report, the global high throughput screening market has been segmented on the basis of technology, products, applications, end users, and geography.
Chromatography Resin Market by Application, Techniques & Type - Trends & Forecast to 2018
MarketsandMarkets

The chromatography resin market is expected to grow at a decent pace during the coming decade driven by its increasing application in monoclonal antibody production and food analytics.
Chromatography Accessories and Consumables Market by Types, Technology & End-users - Trends & Global Forecasts to 2018
MarketsandMarkets

The chromatography accessories and consumables market demands significant investments in R&D in order to constantly come up with new and innovative products and technologies.
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Scientific News
Water In Smog May Reveal Pollution Sources
Vapor variations in SLC inversions tied to cars, furnaces.
New Nanodevice Defeats Drug Resistance
Tiny particles embedded in gel can turn off drug-resistance genes, then release cancer drugs.
Genetically Speaking, Mammals Are More Like Their Fathers
A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.
‘Stem Cell’ Test Could Identify Most Aggressive Breast Cancers
Testing breast cancer cells for how closely they resemble stem cells could identify women with the most aggressive disease, a new study suggests.
DNA Reveals Surprise Connections Between Britain and Europe 8,000 Years Ago
New evidence shows wheat reached Britain 2,000 years before the arrival of wheat farming.
Hookworm Genome Sequenced
UMMS sequences hookworm genome; may lead to new treatments for tropical disease.
A Gene For Brain Size - Only Found In Humans
Following the traces of evolution: Max Planck Researchers find a key to the reproduction of brain stem cells.
A Faster, Less Expensive Way To Analyze Gene Activity
Yale researchers have devised a method that could reduce the time and cost of analyzing gene activity.
Alzheimer's Disease Linked To Heart's Effect On The Brain
Theory suggests that Alzheimer’s Disease has its origin in the heart and vascular system.
NIH Announces $41.5 Million in Funding for the Human Placenta Project
Better understanding of the placenta promises to improve the health of mothers and children.
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Business News
Fidelta Achieves Milestone in Collaboration with LEO Pharma
Next phase of the project will contribute significantly to Fidelta's revenues in 2015.
Genedata Biologics Licensed by Pfizer
Pfizer implements Genedata Biologics to streamline global biopharma R&D processes.
Adaptimmune Strengthens Management Team with Key Executive Hires
Adaptimmune has strengthened its senior management team with the appointment of Dr. Rafael Amado, as Chief Medical Officer, and Adrian (Ad) Rawcliffe, as Chief Financial Officer.
Baxter's Bioscience Business Acquires SuppreMol
Acquisition includes SuppreMol's early-stage pipeline of protein therapeutics for autoimmune and allergic diseases.
Regulatory Submission for Phase 2b Trial for Novel AML Consolidation Treatment
BL-8040 Phase 2b study, as consolidation treatment for AML patients responding to standard induction treatment, is expected to commence shortly after receipt of regulatory approval, anticipated in next few months.
Alizé Pharma Launches Phase II Clinical Trial of AZP-531 in Prader-Willi Syndrome
Results are expected to be available by mid-2016.
Maverix Provides Analytic Support To Rare Genomics Institute Competition
Competition aims to accelerate personalized disease research.
MRC Technology Launches Respiratory ‘Call for Targets’
Project focused on potential small molecule or antibody targets in pathways important in the development or progression of respiratory disease.
Seven Of The Most Promising New Technologies Developed In UK Universities
The Royal Academy of Engineering’s Enterprise Hub has identified seven of the most promising inventors based in UK universities and is supporting them to turn their research into spin-out companies.
Richter And Evestra Enter Into Collaboration Agreement
Gedeon Richeter will provide USD $5-million convertible loan to Evestra.
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Events
AsiaTides 2015
03 Mar 2015
AsiaTides 2015 ...
5th Medical PPM Toolbox confer
05 Mar 2015
5th Medical PPM Toolbox confer ...
8th Lean, Six Sigma, Kaizen an
09 Mar 2015
8th Lean, Six Sigma, Kaizen an ...
Clinical Trial Supply New Engl
10 Mar 2015
Clinical Trial Supply New Engl ...

ePosters
Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications
*Robert-Bosch-GmbH - Robert-Bosch-Platz 1, 70839 Gerlingen-Schillerhöhe, Germany. **University of Freiburg, Department of Microsystems Engineering - IMTEK, 79110 Freiburg, Germany

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.
Direct Targets Identification of a Bioactive Compound
Charnwood Molecular, Hybrigenics services SAS

Identifying protein partners of a small bioactive molecule is of great
interest in many aspects of life sciences and specifically in the drug
discovery and development process cycle. It is a support to (i) decipher
the mechanism of action after for example a “High Content” screening,
(ii) study “off-target” effects, (iii) adjust therapeutic indications and
clinical regimens of a drug and (iv) consider drug repositioning.
3D-Tissue/ Whole-blood Co-culture Models Combined with Multi-Analyte Profile (MAP) Analyses for In-vivo-like Immunopharmacology
HOT Screen GmbH, Reutlingen (Germany)

Human Organotypic Test (HOT) Systems aim at in-vivo like substance characterisation of all preparations meant to act on the human immune system.
A multiplexed amplicon sequencing technology for FFPE and circulating, cell-free DNA
Swift Biosceinces

A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.
Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge TheatreTM


Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge Theatre
Phenotypic Screening Applied to the Anti-biofilm Drug Discovery: Identification of Anti-biofilm Flavonoids from a Chemical Library
1Pharmaceutical Sciences, Department of Biosciences, Åbo Akademi University, Finland 2Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Finland

This work represents a systematic exploration of a flavonoids collection for the inhibitory activity against Staphylococcus aureus biofilms and offers an improved methodological workflow for anti-biofilm screens of chemical libraries taking into account the connections between anti-biofilm and antibacterial properties.
An investigation into the effects of aging on automotive bumper samples by xylene soluble flow injection polymer analysis (XS-FIPA)
Malvern Instruments Ltd

This poster describes the use of flow injection polymer analysis (FIPA) as an analytical tool for xylene soluble (XS) determination with quick and easy simultaneous measurements of molecular weight (MW), intrinsic viscosity (IV) and XS%. The technique was applied to automotive bumper samples which had undergone an aging test. The results from the XS-FIPA technique highlight the differences caused by the aging process.
The role of AHPCO Technology in reducing allergic rhinitis cases as Air Purifier, Surface Sterilizer and Ice Maker sterilizer
1. Life, Earth & Environmental Sciences West Texas A&M University, Canyon, Texas 79015 2. Allergy ARTS, Amarillo, TX 79124 3. Air Oasis, Research and Development, Amarillo, Texas 79118

Dirty ice makers can cause potential health hazards. To prevent any potential contamination, the interior surfaces of the ice machine must be cleaned and sanitized regularly. This report justifies the demand and use of novel equipment that will sanitize the surface of an ice machine continuously. We evaluated the Bi-Polar® unit built by Air Oasis (1.2) in sanitizing the ice machine surface.
Marked increase in basophil activation during non-anaphylactic allergic reactions to peanut in man
Imperial College London

Our data imply an important role for basophils in the evolution of acute IgE-mediated reactions to food allergens.
Ten-Year Experience with Sublingual Immunotherapy for Juniper Pollenosis
Allergy and Asthma Specialists

Efficacy of sublingual immunotherapy for Juniper induced allergic rhinitis is presented.
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Application Notes
Understanding the Effect of Molecular Weight and Structure on the Performance Characteristics of Cellulose Derivatives using OMNISEC
Malvern Instruments Limited

This application note describes the analyses of a variety of aqueous (water-soluble) cellulose derivatives using the OMNISEC triple detection system and the subtle, yet distinct differences between these different derivatives that can be parsed out by the OMNISEC system.
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks using Morphologically Directed Raman Spectroscopy
Malvern Instruments Limited

This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax powder attacks.
Characterization of IgG Monomers & Their Aggregates
Malvern Instruments Limited

In this application note we characterize two antibody samples using column calibration and multi-detection SEC.
Evaluating the Rheological Properties of Hyaluronic Acid Hydrogels for Dermal Filler Applications
Malvern Instruments Limited

The following study shows how rheology and particle size measurements can be used to characterize the physical properties of HA dermal fillers.
Characterization of Pollen Samples with the Morphologi® G3SE
Malvern Instruments Limited

The Morphologi® G3 automated particle characterization system is an analytical tool that provides microscope quality images and delivers statistically significant data through the rapid analysis.
Understanding Antibody and Viral Glycoprotein Interactions Using CG-MALS
Wyatt Technology Corporation

We used size-exclusion chromatography coupled with multi-angle light scattering to determine the molar mass and native oligo-meric state of a viral glycoprotein.
Identification of Insulin Oligomeric States Using SEC-MALS
Wyatt Technology Corporation

This application note shows how the combination of column chromatography (SEC/GPC) with MALS, DLS and RI detection can be applied as a powerful tool to identify monomers, dimers, hexamers and higher aggregates of insulin.
Branching Revealed: Characterizing Molecular Structure in Synthetic and Natural Polymers by Multi-Angle Light Scattering
Wyatt Technology Corporation

Branching represents an important structural parameter of many synthetic and natural polymers, with significant impact on their properties.Wyatt MALS photometers allow direct determination of branching ratio g and number of branch units per molecule.
Discriminating Heparin from Chondroitin Sulfate by Charge:Mass Ratio
Wyatt Technology Corporation

In this study, we compared heparin from two suppliers, including one lot modified with super-sulfated material.
Charge and Interaction Analysis for Predicting Antibody Formulation Stability
Wyatt Technology Corporation

Colloidal stability is a key solution property of a biotherapeutic formulations, indicative of long-term stability. As it is readily measured over much shorter time scales than long-term stability testing or even accelerated testing regimens, measurements of colloidal stability are often utilized in the course of formulation work to screen out poorly behaved conditions.
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