Wednesday, May 22, 2013
 |  |  |
|
|
 | Computational Approaches For The Discovery Of Small Molecule Protein-Protein Interaction Inhibitors Dr Arnout Voet, RIKEN, speaking at Doscpvery Chemistry Congress 2013. |
 | Microelectronics Meets Microfluidics: Hybrid Integration of Sensors in Microfluidic Devices Holger Becker, Microfluidic ChipShop GmbH, speaking at Lab-on-a-Chip World Congress 2012 |
Outsourced Ion Channel Testing Trends 2013
HTStec
HTStec's Outsourced Ion Channel Testing Trends 2013 report was published on 3 May 2013. This 58 page market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on outsourced ion channel testing carried out in April 2013.
qPCR Assay Trends 2013
HTStec
HTStec's qPCR Assay Trends 2013 report was published on 15 April 2013. This 63 page market report summarizes the results of HTStec's 3rd industry-wide global web-based benchmarking survey on real-time quantitative PCR (qPCR) assays and instruments carried out in March 2013.
Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) Market Report 2013
Select Biosciences Ltd
This is the latest and most up-to-date Market Report from Select Biosciences addressing the CTC and CSC markets as they are evolving rapidly.
Cellular Therapy and Cord Blood 2013 Market Report
Select Biosciences Ltd
This is the most up-to-date market report focusing on Cellular Therapy and the HSCT/Cord Blood Market Landscape, published by Select Biosciences.
Phenotypic Drug Discovery Trends 2013
HTStec
HTStec's Phenotypic Drug Discovery Trends 2013 report was published on 20 March 2013. This 59 page market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on phenotypic drug discovery (PDD) carried out in March 2013.
Mass-Spec Based Screening Assay Trends 2013
HTStec
This market report summarizes the results of HTStec's 1st industry-wide global web-based benchmarking survey on mass spectrometry (MS)-based screening assays carried out in February 2013.
Benchtop Automation Trends 2013
HTStec
This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
Stem Cells in Research & Drug Discovery Trends 2012
HTStec
This market report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on stem cells in research and drug discovery carried out in November 2012.
Next-Gen Sequencing Trends 2012
HTStec
This market report summarizes the results of HTStec’s 3rd industry-wide global web-based benchmarking survey on next-generation sequencing (NGS) carried out in November 2012.
Bulk Reagent Dispenser Trends 2012
HTStec
This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on bulk reagent dispensers (BRDs) carried out in October 2012.
HTStec
HTStec's Outsourced Ion Channel Testing Trends 2013 report was published on 3 May 2013. This 58 page market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on outsourced ion channel testing carried out in April 2013.
qPCR Assay Trends 2013
HTStec
HTStec's qPCR Assay Trends 2013 report was published on 15 April 2013. This 63 page market report summarizes the results of HTStec's 3rd industry-wide global web-based benchmarking survey on real-time quantitative PCR (qPCR) assays and instruments carried out in March 2013.
Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) Market Report 2013
Select Biosciences Ltd
This is the latest and most up-to-date Market Report from Select Biosciences addressing the CTC and CSC markets as they are evolving rapidly.
Cellular Therapy and Cord Blood 2013 Market Report
Select Biosciences Ltd
This is the most up-to-date market report focusing on Cellular Therapy and the HSCT/Cord Blood Market Landscape, published by Select Biosciences.
Phenotypic Drug Discovery Trends 2013
HTStec
HTStec's Phenotypic Drug Discovery Trends 2013 report was published on 20 March 2013. This 59 page market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on phenotypic drug discovery (PDD) carried out in March 2013.
Mass-Spec Based Screening Assay Trends 2013
HTStec
This market report summarizes the results of HTStec's 1st industry-wide global web-based benchmarking survey on mass spectrometry (MS)-based screening assays carried out in February 2013.
Benchtop Automation Trends 2013
HTStec
This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
Stem Cells in Research & Drug Discovery Trends 2012
HTStec
This market report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on stem cells in research and drug discovery carried out in November 2012.
Next-Gen Sequencing Trends 2012
HTStec
This market report summarizes the results of HTStec’s 3rd industry-wide global web-based benchmarking survey on next-generation sequencing (NGS) carried out in November 2012.
Bulk Reagent Dispenser Trends 2012
HTStec
This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on bulk reagent dispensers (BRDs) carried out in October 2012.
Clues to Congenital Heart Disease
Non-inherited mutations in hundreds of genes together account for about 1 in 10 cases of severe congenital heart defects.
New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure
Computational Tool Translates Complex Data into 2-Dimensional Images
May allow doctors to track progression of cancer, response to treatment, and risk of relapse.
Program for Breakthrough Biomedical Research to Celebrate 15 Years
A program that fosters basic science projects of potentially high impact is celebrating 15 years of discovery at UC San Francisco.
Environmental Law Institute Recognizes Penn State Wetlands Scientist
Robert P. Brooks, a wetlands scientist at Penn State, has received the 2013 National Wetlands Award for Science Research.
Scientists Identify Molecular Trigger for Alzheimer’s Disease
New research establishes nature of malfunction in protein molecules that can lead to onset of dementia.
TATAA Strengthens Quality Assurance Program
TATAA Biocenter expands offerings using AATI’s Fragment Analyzer™ to assess RNA quality in gene expression analysis.
Non-Wetting Fabric Drains Sweat
Waterproof fabrics that whisk away sweat could be the latest application of microfluidic technology developed by bioengineers.
miRNA Regulated Networks Identified in Cystic Fibrosis
The IDT newsletter DECODED features the latest research to rescue the CFTR functionality.
Osteoarthritis Progression Halted in Mice
If successful in humans, joint replacement surgery might be avoidable.
Non-inherited mutations in hundreds of genes together account for about 1 in 10 cases of severe congenital heart defects.
New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure
Computational Tool Translates Complex Data into 2-Dimensional Images
May allow doctors to track progression of cancer, response to treatment, and risk of relapse.
Program for Breakthrough Biomedical Research to Celebrate 15 Years
A program that fosters basic science projects of potentially high impact is celebrating 15 years of discovery at UC San Francisco.
Environmental Law Institute Recognizes Penn State Wetlands Scientist
Robert P. Brooks, a wetlands scientist at Penn State, has received the 2013 National Wetlands Award for Science Research.
Scientists Identify Molecular Trigger for Alzheimer’s Disease
New research establishes nature of malfunction in protein molecules that can lead to onset of dementia.
TATAA Strengthens Quality Assurance Program
TATAA Biocenter expands offerings using AATI’s Fragment Analyzer™ to assess RNA quality in gene expression analysis.
Non-Wetting Fabric Drains Sweat
Waterproof fabrics that whisk away sweat could be the latest application of microfluidic technology developed by bioengineers.
miRNA Regulated Networks Identified in Cystic Fibrosis
The IDT newsletter DECODED features the latest research to rescue the CFTR functionality.
Osteoarthritis Progression Halted in Mice
If successful in humans, joint replacement surgery might be avoidable.
European and US Cellulase Patents Granted to Direvo
Granted patents describe improved cellulase enzymes having CBH II activity.
The Evolving Relationship of LIMS and Mobile Devices
An Interview with Abbott's Clive Baron about the new STARLIMS Version 11 and how it will leverage mobile devices.
ClinTec International Expands Further in MENA Region with Proposed Opening of Istanbul Office
Company also sponsors Partnerships in Clinical Trials- MENA conference in Istanbul.
Merck Announces $5 Billion Accelerated Share Repurchase
Merck announced that it has entered into an accelerated share repurchase agreement (ASR) with Goldman, Sachs & Co. to repurchase $5 billion of Merck’s common stock.
EMA Validates Gilead’s Marketing Application for Sofosbuvir
Designation granted to new medicines of major public health interest.
Agilent Technologies Introduces OpenLAB Data Store for Mass Spectrometry
Networked Solution Provides Compliant Storage of ICP-MS Data.
Caligor Rx Managing Director Tammy Bishop Elected to Board of Directors for DA4S
Diversity Alliance for Science (DA4S) is a national organization that fosters supplier diversity within the life sciences industry.
Liquidia Technologies Announces Extension of Collaboration with PATH
Company’s virtual conjugate vaccine program shows promise.
Quintiles Recieves Phase II/III Clinical Research Industry Accolade
Biopharma recognizes Quintiles as the leader in customer loyalty among large Clinical Research Organizations (CROs) in quality benchmarking report.
CytRx Announces Initial Results from PK Clinical Trial with Aldoxorubicin
Aldoxorubicin shows prolonged clinical activity in two clinical trial patients with small cell lung cancer who have failed other therapies.
Granted patents describe improved cellulase enzymes having CBH II activity.
The Evolving Relationship of LIMS and Mobile Devices
An Interview with Abbott's Clive Baron about the new STARLIMS Version 11 and how it will leverage mobile devices.
ClinTec International Expands Further in MENA Region with Proposed Opening of Istanbul Office
Company also sponsors Partnerships in Clinical Trials- MENA conference in Istanbul.
Merck Announces $5 Billion Accelerated Share Repurchase
Merck announced that it has entered into an accelerated share repurchase agreement (ASR) with Goldman, Sachs & Co. to repurchase $5 billion of Merck’s common stock.
EMA Validates Gilead’s Marketing Application for Sofosbuvir
Designation granted to new medicines of major public health interest.
Agilent Technologies Introduces OpenLAB Data Store for Mass Spectrometry
Networked Solution Provides Compliant Storage of ICP-MS Data.
Caligor Rx Managing Director Tammy Bishop Elected to Board of Directors for DA4S
Diversity Alliance for Science (DA4S) is a national organization that fosters supplier diversity within the life sciences industry.
Liquidia Technologies Announces Extension of Collaboration with PATH
Company’s virtual conjugate vaccine program shows promise.
Quintiles Recieves Phase II/III Clinical Research Industry Accolade
Biopharma recognizes Quintiles as the leader in customer loyalty among large Clinical Research Organizations (CROs) in quality benchmarking report.
CytRx Announces Initial Results from PK Clinical Trial with Aldoxorubicin
Aldoxorubicin shows prolonged clinical activity in two clinical trial patients with small cell lung cancer who have failed other therapies.
 | ||||||||||||||||
|
Microfluidic Sample Extraction Device with an Integrated Pressure Measurement
IMTEK, University of Freiburg
Bioanalytical applications, like the monitoring of metabolic processes, often require a continuous sample extraction. In this work we describe a microfluidic device which is able to subsequently extract samples in microliter range out of a continuous sample stream and provides an optional integrated channel for the measurement of the fluid pressure.
Concentration and Mixing Effects on the Production of Amine Hydrochloride Salts in a Confined Impinging Jet Reactor
University of Alberta
Results show that different AHC salts can be formed under different process conditions.
Cytosolic Delivery of Anticancer Drug Using Endosomolytic Peptide Bearing Nanoparticles Against Solid Tumor
Dr. Hari Singh Gour University, Sagar
The objective of the present project is to develop transferrin coupled biodegradable nanoparticles (NPs) with high encapsulation efficiency (Doxorubicin). GALA (Glutamic acid-alanine-leucine alanine) a pH sensitive fusogenic endosomolytic peptide is added to the formulation to enhance the endosomal lysis that will further potentiate the delivery of anticancer drug inside tumor cell as well as prevent loss of drug via endosomes.
Highly Efficient Activated Carbon From Palm Shell as an Adsorbent of Toxin/Poison
International Islamic University Malaysia
Highly efficient activated carbon as an adsorbent of toxins has been successfully produced from palm shell through chemical activation process using phosphoric acid as activating agents.
Oral Health Management of a Patient with 47 XYY Syndrome
College of Dentistry, Salman bin Abdulaziz University
The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.
The Challenges of Relieving Cancer Pain: A Literature Review
NHS
This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.
Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies
ReachBio LLC
This study aimed to assess if the CFC assay could also be useful at predicting the increased toxicity of drug combinations relative to the toxicity caused by the relevant single agent.
Predictive in silico Screening to Determine Vector-Mediated Transport Properties for the Blood-Brain Barrier Choline Transporter
University of Wurzburg
An attempt to analyze vector-mediated transport properties for the blood-brain barrier choline transporter (BBBCHT) was made to assess and improve drug delivery to the central nervous system.
Comparison of Dissociated Phoria Measuring Methods. Repeatability and Reliability
CBO
The aim of this study is to determine the reliability and compare reproducibility of different dissociated phoria measure tests.
Fast Liquid Differential Scanning Calorimetry (FLDSC)
Xensor Integration
Lysozyme experiments show that protein unfolding can be recorded at scan rates of up to 1000 °C/s, and for lysozyme concentrations of 1 % and probably even down to 0.1%.
IMTEK, University of Freiburg
Bioanalytical applications, like the monitoring of metabolic processes, often require a continuous sample extraction. In this work we describe a microfluidic device which is able to subsequently extract samples in microliter range out of a continuous sample stream and provides an optional integrated channel for the measurement of the fluid pressure.
Concentration and Mixing Effects on the Production of Amine Hydrochloride Salts in a Confined Impinging Jet Reactor
University of Alberta
Results show that different AHC salts can be formed under different process conditions.
Cytosolic Delivery of Anticancer Drug Using Endosomolytic Peptide Bearing Nanoparticles Against Solid Tumor
Dr. Hari Singh Gour University, Sagar
The objective of the present project is to develop transferrin coupled biodegradable nanoparticles (NPs) with high encapsulation efficiency (Doxorubicin). GALA (Glutamic acid-alanine-leucine alanine) a pH sensitive fusogenic endosomolytic peptide is added to the formulation to enhance the endosomal lysis that will further potentiate the delivery of anticancer drug inside tumor cell as well as prevent loss of drug via endosomes.
Highly Efficient Activated Carbon From Palm Shell as an Adsorbent of Toxin/Poison
International Islamic University Malaysia
Highly efficient activated carbon as an adsorbent of toxins has been successfully produced from palm shell through chemical activation process using phosphoric acid as activating agents.
Oral Health Management of a Patient with 47 XYY Syndrome
College of Dentistry, Salman bin Abdulaziz University
The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.
The Challenges of Relieving Cancer Pain: A Literature Review
NHS
This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.
Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies
ReachBio LLC
This study aimed to assess if the CFC assay could also be useful at predicting the increased toxicity of drug combinations relative to the toxicity caused by the relevant single agent.
Predictive in silico Screening to Determine Vector-Mediated Transport Properties for the Blood-Brain Barrier Choline Transporter
University of Wurzburg
An attempt to analyze vector-mediated transport properties for the blood-brain barrier choline transporter (BBBCHT) was made to assess and improve drug delivery to the central nervous system.
Comparison of Dissociated Phoria Measuring Methods. Repeatability and Reliability
CBO
The aim of this study is to determine the reliability and compare reproducibility of different dissociated phoria measure tests.
Fast Liquid Differential Scanning Calorimetry (FLDSC)
Xensor Integration
Lysozyme experiments show that protein unfolding can be recorded at scan rates of up to 1000 °C/s, and for lysozyme concentrations of 1 % and probably even down to 0.1%.
An Integrated Solution to Simplify Library Preparation and Multiplexing for NimbleGen Sequence Capture
Bioo Scientific
The studies described herein demonstrate the capability of Bioo Scientific’s novel NEXTFlex™ DNA Pre-Capture Combo Library construction kits used in conjunction with the NimbleGen Sequence Capture technology to obtain high coverage comparative genomic data from a panel of human HapMap DNA samples.
Direct Visualisation, Sizing and Counting of Aggregation in Proteins
NanoSight Ltd
Characterising the state of aggregation in proteins is of paramount importance when trying to understand biopharmaceutical product stability and efficacy. Product quality, both in terms of biological activity and immunogenicity can be highly influenced by the state of protein aggregation.
Direct Visualisation, Sizing & Counting of Viruses and Phages in Liquid Suspension
NanoSight Ltd
A new laser-based nanoparticle tracking analysis system is now available which allows nanoscale particles such as viruses and virus aggregates to be directly and individually visualised in liquids in real-time, from which high-resolution particle size distribution profiles can be obtained.
ORAC Assay for the Determination of Antioxidant Capacity in Foods
Tecan Group - Products
Measuring oxygen radical absorbance capacity with the Infinite® 200 PRO multimode reader.
Automated Growth Monitoring of Microaerophilic Organisms
Tecan Group - Products
Walkaway growth monitoring of Helicobacter pylori in the Infinite® 200 PRO reader with Gas Control Module (GCM™).
Rapid Critical Micelle Concentration (CMC) Determination Using Fluorescence Polarization
BioTek Instruments
The determination of the critical micelle concentration (CMC) value of surfactants under different environmental conditions is important for a number of different biological and chemical processes. Because the CMC is not a constant value, shifting with different environmental conditions, it is important that a rapid, reliable and easy methodology be available to facilitate testing.
Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization Assay
Biotek Instruments
Support Synergy™ Neo launch by providing speed and sensitivity data for Fluorescence Polarization detection mode in low volume 384-well plate using hERG biochemical assay as a Model.
BRD4 Bromodomain 1 Inhibitor Screening Using a Homogeneous Proximity Assay
BioTek Instruments
Demonstration of profiling and primary screening of an epigenetic target; a histone acetylating bromodomain. This is a TR-FRET based application highlighting the use of automated instrumentation and a high-throughput screening (HTS) multi-mode microplate reader.
Integration of Liquid Handler Quality Control Into the HTS Daily Routine
Artel
This application note describes how the Artel MVS® Multichannel Verification System can be used to assess the performance of the liquid handlers integrated into a PerkinElmer cell::explorer high throughput screening (HTS) system.
Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton
In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
Bioo Scientific
The studies described herein demonstrate the capability of Bioo Scientific’s novel NEXTFlex™ DNA Pre-Capture Combo Library construction kits used in conjunction with the NimbleGen Sequence Capture technology to obtain high coverage comparative genomic data from a panel of human HapMap DNA samples.
Direct Visualisation, Sizing and Counting of Aggregation in Proteins
NanoSight Ltd
Characterising the state of aggregation in proteins is of paramount importance when trying to understand biopharmaceutical product stability and efficacy. Product quality, both in terms of biological activity and immunogenicity can be highly influenced by the state of protein aggregation.
Direct Visualisation, Sizing & Counting of Viruses and Phages in Liquid Suspension
NanoSight Ltd
A new laser-based nanoparticle tracking analysis system is now available which allows nanoscale particles such as viruses and virus aggregates to be directly and individually visualised in liquids in real-time, from which high-resolution particle size distribution profiles can be obtained.
ORAC Assay for the Determination of Antioxidant Capacity in Foods
Tecan Group - Products
Measuring oxygen radical absorbance capacity with the Infinite® 200 PRO multimode reader.
Automated Growth Monitoring of Microaerophilic Organisms
Tecan Group - Products
Walkaway growth monitoring of Helicobacter pylori in the Infinite® 200 PRO reader with Gas Control Module (GCM™).
Rapid Critical Micelle Concentration (CMC) Determination Using Fluorescence Polarization
BioTek Instruments
The determination of the critical micelle concentration (CMC) value of surfactants under different environmental conditions is important for a number of different biological and chemical processes. Because the CMC is not a constant value, shifting with different environmental conditions, it is important that a rapid, reliable and easy methodology be available to facilitate testing.
Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization Assay
Biotek Instruments
Support Synergy™ Neo launch by providing speed and sensitivity data for Fluorescence Polarization detection mode in low volume 384-well plate using hERG biochemical assay as a Model.
BRD4 Bromodomain 1 Inhibitor Screening Using a Homogeneous Proximity Assay
BioTek Instruments
Demonstration of profiling and primary screening of an epigenetic target; a histone acetylating bromodomain. This is a TR-FRET based application highlighting the use of automated instrumentation and a high-throughput screening (HTS) multi-mode microplate reader.
Integration of Liquid Handler Quality Control Into the HTS Daily Routine
Artel
This application note describes how the Artel MVS® Multichannel Verification System can be used to assess the performance of the liquid handlers integrated into a PerkinElmer cell::explorer high throughput screening (HTS) system.
Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton
In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
©2013 Technology Networks, all rights reserved.