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Webcasts
Mass spectrometry based metabolomics in chemical and nanomaterial risk assessmentMass spectrometry based metabolomics in chemical and nanomaterial risk assessment
In this webinar, Mark Viant, Professor of Metabolomics at the University of Birmingham, will introduce the concepts of metabolomics as well as the challenges faced in chemical hazard assessment.
High-Throughput Approaches to Cell BiologyHigh-Throughput Approaches to Cell Biology
Robin Ketteler, University College London, speaking at Screening Europe 2015.

Market Reports
Critical Care Therapeutics in Major Developed Markets to 2020
GBI Research

The report provides in-depth analysis of the critical care market in the US, UK, France, Germany, Italy, Spain, Japan and Canada with an estimation of market size for 2013, along with market forecasts to 2020.
Apheresis Market, Applications, Devices & Disposables - Forecasts to 2017
MarketsandMarkets

The research report categorizes this market into procedure, application, technology, product type and end-user. All these markets are broken down into segments and sub-segments, providing exhaustive value analysis for 2010, 2011 and 2012, as well as forecast up to 2017.
Inherited Orphan Blood Disorders Therapeutics Market to 2019
GBI Research

The report provides insights into the up-and-coming trends of a portion of the inherited orphan blood disorder pharmaceutical market by examining sickle cell anemia, thalassemia and Hereditary Angioedema (HAE) in seven major markets.
Global Molecular Cytogenetics Market 2014-2018
Technavio

This report covers the present scenario and the growth prospects of the Global Molecular Cytogenetics market for the period 2014-2018.
Tissue Diagnostics Market by Technology, Disease, Product, End-Users & Region - Trends & Forecast to 2018
MarketsandMarkets

The report provides qualitative insights about key market shares, growth rates, and market drivers for all important sub-segments. It maps the market sizes and growth rates of each sub-segment and identifies the segments poised for rapid growth in each of the 20 geographic and regional segments.
Digital Pathology Market by Slide Scanners, Analytics, Delivery Modes & by Whole Slide Image Storage - Global Forecasts & Trends to 2018
MarketsandMarkets

The global digital pathology market was valued at an estimated $250.2 million in 2013 and is expected to grow at a CAGR of 11.8%, to reach an estimated $437 million by 2018.
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
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Scientific News
Label-Free Binding Analysis Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
‘Measuring Stick’ Standard for Gene Sequencing Now Available from NIST
New reference material, NIST RM 8398, to “map” DNA for genetic testing.
Single-cell Analysis Hits its Stride
Advances in technology and computational analysis enable scale and affordability, paving the way for translational studies.
Freshly Squeezed Vaccines
Microfluidic cell-squeezing device opens new possibilities for cell-based vaccines.
It Runs in the Family
Distantly related viruses share a common machinery for replication.
Scientists Create Mice with a Major Genetic Cause of ALS and FTD
NIH-funded study provides new platform for testing treatments for several neurodegenerative disorders.
New Target for Treating Rheumatoid Arthritis
Many affected individuals still suffer with progressive joint damage, despite treatment. This study has discovered a new treatment target which could open a door to preventing this ongoing damage.
Shining A New Light On The Immune System
Scientists at the University of St Andrews have developed a revolutionary method of identifying cells of the immune system with “molecular fingerprints” which could pave the way for the rapid detection of conditions such as leukaemia and lymphoma from a small blood sample.
Inexpensive Technique Developed to Manufacture Nanofibers
Current methods for producing nanofibers are incredibly costly and therefore limit accessibility, this new study opens the door to cheap, mass produced nanofibers.
Normal Skin Accrues High Number of Mutations Associated with Cancer
Researchers used genomic sequencing to gain insights into how somatic mutations build up in normal cells before the onset of cancer, a process that is poorly understood.
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Business News
Pacific Biosciences and RainDance Technologies Partner
Partnership combines Pacific Biosciences’ Single Molecule, Real-Time (SMRT®) Sequencing and informatics capabilities with RainDance’s proprietary digital droplet and single molecule barcoding technology.
FDA Grants Fast Track Designation to ReNeuron’s RP Cell Therapy Candidate
Approval to commence a Phase I/II clinical trial in the US with stem cell therapy candidate for RP.
Isarna Announces Orphan Drug Designation for ISTH0036
Orphan drug designation in the European Union to treat advanced-stage glaucoma.
UT Southwestern Faculty Members Named HHMI Investigators
Appointment of Dr. Kim Orth and Dr. Joshua Mendell to HHMI.
Pharmatek Expands Spray Drying Capabilities
New spray dryer strengthens the Company’s portfolio of solutions for poorly soluble compounds.
Janssen Expands Collaboration with Rutgers School of Engineering
$6 million funding arrangement to implement continuous manufacturing initiative.
Körber Medipak Systems Opens New Location in Sao Paulo
Offers complete portfolio of solutions and services.
Baxter Receives U.S. FDA Approval for 0.9% Sodium Chloride Injection
Additional site approval comes amid increased industry demand for sterile IV solutions.
Boehringer Ingelheim Acquires Pharmaxis’ Phase 1 Anti-inflammatory Drug Candidate
Company exercises option and acquires global ownership of Pharmaxis’ investigational anti-inflammatory drug candidate PXS4728A, including associated intellectual property rights.
Genzyme to Collaborate with Ablynx on MS Research Project
Research collaboration to investigate Nanobodies® against a target that plays an important role in multiple sclerosis.
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Events
XIII Bionnale
27 May 2015
XIII Bionnale ...
Americas Antibody Congress 201
27 May 2015
Americas Antibody Congress 201 ...
Cell Culture World Congress US
27 May 2015
Cell Culture World Congress US ...
World Biosimilars Congress USA
27 May 2015
World Biosimilars Congress USA ...

ePosters
Single Cell Whole Genome Amplification
GE Global Research

The analysis of genomes at the single cell level offers unprecedented biological insights in diverse fields such as cancer research, immunology & microbiology. This poster discusses the a technology for amplification of genomic DNA form a single cell, that provides utmost sensitivity, accuracy & robustness. GE Healthcare Life Sciences had previously developed method of multiple strand displacement amplification (MDA) by Phi29 DNA polymerase
The Prestwick Chemical Library (R), A Valuable Tool for Screening
1. Prestwick Chemical, 220 Blvd Gonthier d'Andernach, 67400 Strasbourg-Illkirch, FRANCE 2. University of Strasbourg, Therapeuthic Innovation Laboratory, UMR7200 CNRS, Faculty of Pharmacy, 74 route du

The Prestwick Chemical Library® (PCL) is Prestwick’s flagship product dedicated to screening. It is a collection of 1280 molecules comprising 100% approved drugs (FDA, EMEA and other agencies) selected for their high chemical and pharmacological diversity. The PCL was designed to reduce the risk of "low quality" hits and therefore the cost of the initial screening, and appears to be an efficient smart library for hit discovery. The PCL comes with an extended fully-annotated database.
System-Specific Periodicity in qPCR Data and its Impact on Quantitation
1Dept. of Chemistry, Vanderbilt Univ., Nashville, TN USA 37235; 2 BTU Cottbus-Senftenberg, Senftenberg, Germany; 3 Dept. of Andrology, Univ. Hospital Hamburg-Eppendorf, Germany

In some commercial qPCR instruments, the fluorescence signal shows reaction-to-reaction periodicity in all cycles, and this translates into periodicity in threshold-based Cq markers.
Bovine RNA-seq data analysis of liver and pituitary gland
(1) Functional Genomics Lab. Faculty of Biology and Environmental Protection, Nicolaus Copernicus University, Torun, Poland, (2) Interdisciplinary Centre of Modern Technology, Nicolaus Copernicus Uni

Two key applications of RNA-seq i.e., i) transcriptome read mapping to a reference genome and ii) SNP detections were investigated to analysis of bovine liver and pituitary gland transcriptome. Here, we have presented ONLY the obtained results of bovine pituitary gland.
A proteomic analysis of p27kip1-binding proteins reveals a putative role in transcription regulation through RNA polymerase II interaction
1.-Department of Cell Biology, Immunology and Neurosciences, University of Barcelona-IDIBAPS, Barcelona, Spain 2.-INSERM UMR1037-Cancer Research Center of Tolouse, Universite de Tolouse, CNRS ERL5294

A proteomic analysis of p27kip1-binding proteins reveals a putative role in transcription regulation through RNA polymerase II interaction
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
TriLink BioTechnologies

We describe an optimized workflow which suppresses adapter dimers, works with low RNA input and eliminates the need for a gel purification step.
Whole Transcriptome RNA-SEQ with Ion Torrent Platform: FFPE, Fresh LCM and FFPE LCM Samples. Increasingly Difficult
1Pisa Science Founda:on, Pisa; Italy 2Department of Pathology, Pisa University Hospital, Pisa, Italy

We developed a high performance method to analyze the whole transcriptome of our FFPE samples, obtaining a very high number of reads (78,186,377 usable reads) perfectly comparable with samples with a large amount of RNA such as samples obtained from cells or fresh tissues.
Study Of The Active Bacterial Community In Two Membrane Bioreactors
1 Research Institute of Water and Environmental Ingeneering (IIAMA), Polytechnic University of Valencia 2 I+D+i Department , Urbaser S.A.

In this work, bacterial communities from two MBR systems treating leachates were evaluated using the 16S rRNA metagenomics approach, with and without a viability dye (Propidium Monoazide, PMA).
Quantitative Analysis Of Pesticides In Quechers Extracts Using UPLC- and APGC- MS/MS
Waters Corporation, Wilmslow, SK9 4AX, United Kingdom

In this study, we demonstrate sensitive, accurate and repeatable results for the analysis of pesticides in QuEChERS extracts of a selection of
commodities below the regulatory limits.
Rapid Biosensor-Based Detection of Environmental Contamination by Petroleum Hydrocarbons, PAHs and Heavy Metals
Wilton Biotechnologies Ltd., Tetricus Science Park, Porton Down, Salisbury

In this study, we evaluated different freeze-drying excipients to stabilise the biosensor and remove the requirement to store bacteria at -20??C.
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Application Notes
Assessing Product Stability During Transportation Using A Rotational Rheometer
Malvern Instruments Limited

This note discusses a simple rheological test for assessing product stability during transportation.
Dependance of Viscosity and Foam Consistency on Gas Volume Fraction
Malvern Instruments Limited

This note describes an empirical method for correlating foam rheology with gas volume fraction.
Predicting the Compounding Performance of Pressure Sensitive Adhesives (PSA’s)
Malvern Instruments Limited

This note discusses a method for assessing pump-ability and mix-ability of Pressure Sensitive Adhesives during manufacture.
Structural Elucidation of Dextrans and other Polysaccharides using OMNISEC Multi- Detection GPC
Malvern Instruments Limited

A series of dextran samples ranging in molecular weight from about 1– 650 kDa are characterized using OMNISEC. Structural comparisons to other polysaccharides, gum arabic and pectin are presented.
Evaluating Non-linear Viscoelastic Effects Using Normal Force Measurements on a Rotational Rheometer
Malvern Instruments Limited

This note discusses how non-linear viscoelastic effects can be evaluated using normal force measurements on a rotational rheometer.
Effect of Droplet Concentration on Emulsion Viscosity
Malvern Instruments Limited

This note discusses how rotational rheometry can be used to evaluate the impact of droplet concentration on emulsion viscosity
Predicting the Stability of Dispersions with a Yield Stress
Malvern Instruments Limited

This application note shows methodology and data for evaluating the stability of two shower gel (bodywash) products against their capability to suspend bubbles as a product requirement.
Characterizing Opthalmic Viscosurgical Devices (OVDs) Using A Aotational Rheometer
Malvern Instruments Limited

This application note discusses the methodology and results for the rheological characterization of Opthalmic Viscosurgical Devices (OVDs) according to the International Standard ISO15798:2013
Detecting the Presence of Anomolous Large Particles Within Powders Using Laser Diffraction Particle Size Analysis
Malvern Instruments Limited

In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials dosed with large particles and to detect those large, anomalous particles.
Measuring Small Quantities of Dry Powder Using the Aero S and Mastersizer 3000
Malvern Instruments Limited

In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials with good reproducibility and illustrating the dispersion abilities of the Aero S.
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