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Webcasts
Worried about your cell-based assays? Remote monitoring with CNS offers complete peace of mind!Worried about your cell-based assays? Remote monitoring with CNS offers complete peace of mind!
Michael Fejtl, Market Manager, Tecan Austria
Challenges of Implementing and Validating CTC Assays in Oncology Clinical TrialsChallenges of Implementing and Validating CTC Assays in Oncology Clinical Trials
Iman Jilani, Pfizer, speaking at Exosomes and Circulating Biomarkers Summit 2013.

Market Reports
Flow Chemistry Market by Reactor Type, Application & Geography - Trends & Forecast to 2018
MarketsandMarkets

This report Flow Chemistry Market is segmented by type of reactor with major focus on micro reactor systems. The micro reactor system market is further segmented by type along with geography and applications.
Facial Recognition Market: Global Advancements, Emerging Applications, Business Models and Worldwide Market Forecasts and Analysis (2013 ? 2018)
MarketsandMarkets

The report is focused to give a birds eye-view of the complete facial recognition industry with regards to technology and solutions, software, hardware and services. It also provides revenue distribution of the market based on various industry vertical or end-users.
Biomarkers Market 2013 - 2020
Allied Market Research

Disease diagnostic application remains the key area of application that is expected to reach 6.1 $billion in 2020. However, application of diagnostic biomarkers in forensics and molecular diagnostics is catching up quite significantly. Molecular diagnostics is expected to grow at a CAGR of 17.6% from 2013 to 2020.
Mass Spectrometry for Clinical Diagnostics Applications 2013 Focus Report
SELECTBIO

This report from SELECTBIO addresses a number of topics including, market segmentation, market landscape, and mass spectrometry products currently on the market as well as in development.
Liposomes
RI Technologies

This market insight report on liposomes gives an insight into global liposomes market. The report provides market analytics by application, and by therapeutic area.
Stem Cell Research
Stem Cell Research

This report on Stem Cell Research gives a market insight into the ever progressing and debatable market of Stem Cell Research segmented by type, technology and therapeutic area.
Stem Cell Research in Cardiology
RI Technologies

The report serves as a guide to global market for stem cells in cardiology covering more than 230 companies that are engaged in stem cell R&D, storage, banking, discovery, testing and supply of products and services.
Security Technologies in Biotechnology
RI Technologies

The report serves as a guide to security technology industry for biotechnology applications, covering more than 350 companies that are engaged in security technology/products and services.
RNAi
RI Technologies

The report serves as a guide to global RNAi industry covering 280 plus companies that are engaged in RNAi synthesis, R&D, therapeutics, test kits, tools and services.
Polylactic Acid
RI Technologies

This market insight report provides market analytics by form, and by application. The market is divided by form into films & sheets, coatings, fibers and other; and by Application into food, textile, medical, and other.
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Scientific News
Muscle Weakness Seen in Alcoholism Linked to Mitochondrial Repair Issues
Scientists found evidence that chronic heavy alcohol use affects a gene involved in mitochondrial repair and muscle regeneration.
Diagnosis of Bladder Cancer and Prediction of Survival by Urinary Metabolomics
Bladder cancer seems to be ideal for urinary metabolomics-based diagnosis, as urine can directly contact the cancer lesion in the bladder.
Gene Linked to Excess Male Hormones in Female Infertility Disorder
Discovery by NIH-supported researchers may lead to diagnostic test, treatment.
How a Silly Putty Ingredient Could Advance Stem Cell Therapies
The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become.
Domainex Programme Shows Great Promise for the Treatment of Inflammatory Diseases
Company’s IKKe/TBK1 programme to offer a disease-modifying treatment for COPD patients.
Nanocrystalline Cellulose Modified into an Efficient Viral Inhibitor
Researchers have succeeded in creating a surface on nano-sized cellulose crystals that imitates a biological structure.
Drug Does Not Improve Set of Cardiovascular Outcomes for Diastolic Heart Failure
NIH-supported study finds drug does appear to reduce hospitalizations for diastolic heart failure.
Will Forensic Biology Become Forensic Molecular Biology?
The article presents some examples of the potential for new molecular biology technologies to assist in the investigation of crime.
Lab Scale Manufacturing Using Continuous Crystallization
A new METTLER TOLEDO On-demand webinar explores recent research that could revolutionize pharmaceutical production.
Unexpected Protein Partnership has Implications for Cancer Treatment
Scientists have identified a macrophage that works together in response to cancer drugs to increase inflammation in a way that may alter tumor growth.
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Business News
Pittcon 2014 Informatics Wrap-Up
Applications focus on better, faster, cheaper data management in the lab.
Alfa Aesar Introduces New “GET” Channel Partner Program
An excellent opportunity for new partners to emerge for Alfa Aesar.
Hottest Industry Trends in Life Sciences Sector 2014
Meaningful “quick read” whitepaper “Life Science Trends 2014” also offers exclusive feature article on Big Data in the Life Sciences.
Crown Bioscience Passes 1000 Model Mark in PDX Collection for Oncology Drug Discovery
Size of collection allows for more informed preclinical decision making on prospective drug candidates.
AMSBIO Expands US Operations
Company announces opening of a new North American headquarters in Cambridge, MA.
Beckman To Acquire Cytometer Developer Xitogen
Acquisition will broaden product offering, providing an Asian operations centre.
Novartis Announces Portfolio Transformation
Company launches a major overhaul of its business, unveiling a series of multibillion-dollar deals with GSK and Eli Lilly.
Quest Diagnostics Completes Acquisition of Summit Health
Summit's clients will access Quest's 2,200 patient service centers, biometric analysis.
Emerging Technologies Redefine Infectious Disease Diagnostics
The largest opportunities lie in the developing regions of Asia, Africa and Latin America.
Thermo Reports 22% Revenue Rise in Q1 2014
Results include the addition of Life Technologies as of February 4, 2014, and exclude the previously announced related divestitures as of March 22, 2014.
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Events
Diabetes Summit 2014 
23 Apr 2014
Diabetes Summit 2014  ...
7th Diabetes Drug Discovery &
24 Apr 2014
7th Diabetes Drug Discovery & ...
4th Diabetes Partnering and De
23 Apr 2014
4th Diabetes Partnering and De ...
Stem Cell Summit 2014 
23 Apr 2014
Stem Cell Summit 2014  ...

ePosters
High-throughput analysis of protein formulations by DLS
Wyatt Technology Corporation

High-throughput analysis of protein formulations by Dynamic Light Scattering (DLS): thermal stability, colloidal stability and a thermal anomaly in the colloidal stability parameter D1
GC-MS Comparison of Lavindin Grosso Oil Obtained by Steam Distillation and SFE
Miami University Middletown

Oil was extracted from Lavindin Grosso using steam distillation and using supercritical fluid extraction (SFE). Multiple analyses of the same extract demonstrated repeatability of the analytical method. The variability between batches of distillate bracketed the composition obtained by SFE. The differences among the oils could be attributed more to where the lavender was grown than to the extraction method.
Digital microphotographic atlas of the adult zebrafish cerebellum
Wagner College

Sagittal, coronal and horizontal, one micron thick plastic (semithin) sections of adult zebrafish (Danio rerio) brain were photographed in 40X. The sections were then photomontaged together using in Adobe Photoshop CS5 Extended Version 12.0 to make the photographic atlas.
The Effects of Dimethylphthalate on the Viability and Development of Drosophila melanogaster
Wagner College

My research studies the effect of dimethylphthalate (DMP), a putative endocrine disruptor, on the viability and development of the model organism Drosophila melanogaster.
Microwave Assisted Green Synthesis of Aspirin From Over The Counter Pain Creams
Division of Natural Science, Mount Saint Mary College, NY

A successful microwave synthesis of methyl salicylate to aspirin using green catalysts from over the counter pain creams. The process was also prepared and tested in an undergraduate organic chemistry lab.
Analytical Pipetting of Serum
Artel

Many types of chemical and biological analyses are based upon analytical techniques involving accurate delivery of liquid components. Pipetting tools have become commonplace especially in many biological and pharmaceutical laboratories. While these tools are familiar to many, their operational differences when pipetting different types of solutions are often over-looked.
Targeted cancer therapy based on blocking the expression of genes and small doses of oxaliplatin.
Centre for Medical Genetics Russian Academy of Medical Sciences, Koltsov Institute of Developmental Biology Russian Academy of Sciences

The major drawbacks of the prescribed chemotherapy, are still remain the significant side effects and drug - resistance. Even targeted chemotherapy by means of specific antibodies do not always help to solve these complications. Our purpose was to identify potential biological targets associated with the development of drug resistance and to develop a specific method of suppressing the viability of cancer cells exposed to low doses of standard chemotherapy.
Comparison of Three Methods for the Evaluation of Cytokine Storm Risk in Early and Clinical Stage Biopharmaceutical Development
ReachBio LLC

Objective: To identify an assay that can accurately predict the risk of CRS and CS associated with investigational biotherapeutics. A comparison of three methods were used: (a) immobilization of test antibody on plastic, (b) co-culture of PBMC's on HUVEC's and (c) pre-culture of PBMC's at high cell density.
Cloud Point Extraction of Metal Oxide Nanoparticles in Water Samples Identified by Raman Spectroscopy and Quantified by Atomic Absorption Spectroscopy
Department of Chemistry, Tennessee Technological University, Cookeville, TN 38505-0001, USA

Nanoparticles that are widely used in commercial products pose a threat to human health and the environment. This project proposes a cheaper and more effective method to identify and quantify metal oxide nanoparticles in water samples.
Cloud Point Extraction of Metal Oxide Nanoparticles in Water Samples Identified by Raman Spectroscopy and Quantified by Atomic Absorption Spectroscopy
Department of Chemistry, Tennessee Technological University, Cookeville, TN 38505-0001, USA

Nanoparticles that are widely used in commercial products pose a threat to human health and the environment. This project proposes a cheaper and more effective method to identify and quantify metal oxide nanoparticles in water samples.
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Application Notes
Performing ADCC Reporter Bioassay with an Environmentally Controlled Microplate Reader
Tecan Group Ltd.

The Promega ADCC Reporter Bioassay provides effector and target cells in frozen, thaw-and-use format, removing the need for isolating or culturing cells in order to perform the assay. Reporter induction requires a six-hour to overnight incubation in a standard cell culture incubator. The CO2 and temperature control features of the Tecan Infinite® 200 PRO with GCM allow the assay induction to be performed without the requirement for a cell culture incubator.
Tecan AC Extraction Plate™
Tecan Group Ltd.

A growing number of laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) for the determination of vitamin D. The advantage of the latter method is unparalleled specificity combined with high sensitivity, offering the potential for the determination of multiple analytes, such as 25OH-vitamin D3 and 25OH-vitamin D2.
Tecan AC Extraction Plate™
Tecan Group Ltd.

There is an increasing demand for the determination of Vitamin D status which is based on the quantification of the two metabolites 25-OH-Vitamin D3/D2. Numerous laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) because of its specificity combined with high sensitivity. Moreover LC-MS/MS offers the potential for multianalyte determination which is required for Vitamin D status determination.
Tecan AC Extraction Plate™
Tecan Group Ltd.

THC , the main active compound in marijuana, is metabolized to ?9-(11-OH)-tetrahydrocannabinol (11-OH-THC) and 11-nor-?9-carboxy-tetrahydrocannabinol (THC-COOH). Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Tecan AC Extraction Plate™
Tecan Group Ltd.

Testosterone is a powerful androgen that is primarily secreted by Leydig cells in men and theca cells in women. For accurate, reproducible quantification of testosterone, a growing number of laboratories is shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS). This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.
Creating dose-response curves for cell-based and biochemical assays with the HP D300 Digital Dispenser
Tecan Group Ltd.

Small molecule drug discovery relies on the evaluation of one compound against another compound. Measurement of the activity of the small molecule against a target must be standardized by determining the IC50 or EC50 value using does response curve. The classical method of generating a dose-response curve is via serial dilution; however this approach has a number of drawbacks. Today, there is an alternative solution which eliminates these limitations: the HP D300 Digital Dispenser.
Tag-lite® two-cell assay: a valuable tool for protein drug discovery
Tecan Group Ltd.

Antibodies are central mediators of the immune system, IgG being the most dominant. Binding of IgG/antigen complexes to membrane-bound Fc? receptors triggers a cellular immune response. Alterations in the Fc portion of the antibody by introducing mutations can lead to complete abolition of Fc? receptor binding. This describes the development of a cellbased TR-FRET assay to determine the simultaneous binding of an antibody to its antigen and huFc?RIIIa present on different cells.
Transcreener® ADP2 TR-FRET Red Assay
Tecan Group Ltd.

Adenosine diphosphate (ADP) is an important mediator of cellular metabolism that is essential for maintaining energy levels. The Transcreener ADP2 TR-FRET Red Assay is intended for the detection of ADP production by any kinase or ATPase, and has been developed specifically for high throughput screening applications.
3D Cell Culture: mimicking real tissue
Tecan Group Ltd.

Technological advances in the last couple of years have enabled 3D scaffolds to be engineered that offer a real proxy for the in vivo environment which can be easily and routinely used in a cell culture laboratory. Alvetex Scaffold enables cells to develop natural, in vivo-like intercellular interactions, providing an ideal environment for real three-dimensional growth and nutrient exchange that is comparable to intra-capillary exchange in living tissues.
Colony Picking - fully automated screening of fungi
Tecan Group Ltd.

Manual screening processes are very costly and time consuming. This ambitious project for high throughput screening (HTS) of cellulase-producing fungal strains demonstrates the high capacity and unique features of the Freedom EVO colony picking workstation. The picking of fungi is more complex than for typical bacterial colonies, and requires advanced selection criteria to be combined with complex pipetting and a tip movement that mimics the manual picking process.
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