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Webcasts
Mass spectrometry based metabolomics in chemical and nanomaterial risk assessmentMass spectrometry based metabolomics in chemical and nanomaterial risk assessment
In this webinar, Mark Viant, Professor of Metabolomics at the University of Birmingham, will introduce the concepts of metabolomics as well as the challenges faced in chemical hazard assessment.
Imaging Biomarkers - Future or RealityImaging Biomarkers - Future or Reality
Edwin van Beek, University of Edinburgh, speaking at Diagnostics & Biomarkers 2015.

Market Reports
Critical Care Therapeutics in Major Developed Markets to 2020
GBI Research

The report provides in-depth analysis of the critical care market in the US, UK, France, Germany, Italy, Spain, Japan and Canada with an estimation of market size for 2013, along with market forecasts to 2020.
Apheresis Market, Applications, Devices & Disposables - Forecasts to 2017
MarketsandMarkets

The research report categorizes this market into procedure, application, technology, product type and end-user. All these markets are broken down into segments and sub-segments, providing exhaustive value analysis for 2010, 2011 and 2012, as well as forecast up to 2017.
Inherited Orphan Blood Disorders Therapeutics Market to 2019
GBI Research

The report provides insights into the up-and-coming trends of a portion of the inherited orphan blood disorder pharmaceutical market by examining sickle cell anemia, thalassemia and Hereditary Angioedema (HAE) in seven major markets.
Global Molecular Cytogenetics Market 2014-2018
Technavio

This report covers the present scenario and the growth prospects of the Global Molecular Cytogenetics market for the period 2014-2018.
Tissue Diagnostics Market by Technology, Disease, Product, End-Users & Region - Trends & Forecast to 2018
MarketsandMarkets

The report provides qualitative insights about key market shares, growth rates, and market drivers for all important sub-segments. It maps the market sizes and growth rates of each sub-segment and identifies the segments poised for rapid growth in each of the 20 geographic and regional segments.
Digital Pathology Market by Slide Scanners, Analytics, Delivery Modes & by Whole Slide Image Storage - Global Forecasts & Trends to 2018
MarketsandMarkets

The global digital pathology market was valued at an estimated $250.2 million in 2013 and is expected to grow at a CAGR of 11.8%, to reach an estimated $437 million by 2018.
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
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Scientific News
Starting Antiretroviral Treatment Early Improves Outcomes for HIV-infected Individuals
NIH-funded trial results likely will impact global treatment guidelines.
Scientists are Designing Decoy Drugs to Fool Cancer
Study shows potential of drugs that can target the Notch switch with reduced toxicity.
Viral Immunotherapy For Skin Cancer Shows Patient Benefit
A genetically engineered herpes virus can halt the progression of skin cancer by killing cancer cells and sparking the immune system into action against tumours, a landmark clinical trial has shown.
Seeing the Action
Researchers have developed a way to observe both the forces present and the behavior that occurs during cell hemifusion; the merging of the lipid bi-layers of two cells.
Non-Aqueous Solvent Supports DNA Nanotech
Researchers at the Georgia Institute of Technology have now shown that they can assemble DNA nano-structures in a solvent containing no water.
‘Rosetta Stone’ for Prostate Cancer Mutations
Scientists have produced a comprehensive genetic map of the mutations in prostate cancer that have spread across the body.
From Worker to Queen at the Drop of a Gene
Biologists have found that the hierarchical fate of one of nature's most important pollinators comes down to which genes are "turned on or off".
New Chip Makes Testing For Antibiotic-Resistant Bacteria Faster, Easier
Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time.
Two New and Very Large Classes of RNAs Linked to a Cancer Biomarker Identified
Study shows two new classes of RNAs could play a role in progression of prostate cancer.
Tiny Spheres Of Human Cells Mimic The Brain
Researchers have figured out how to create spheres of neuronal cells resembling the cerebral cortex, making functional human brain tissue available for the first time to study neuropsychiatric diseases such as autism and schizophrenia.
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Business News
Merck Millipore Enters Into Agreement with Singulex
Acquiring exclusive worldwide rights to Singulex’s SMC™ technology - instruments, assays and services - for research applications.
Quintiles Launches New Solution for Emerging Asia-Pacific Companies
Emerging Companies give region strong base to transform global healthcare.
AbbVie Completes Acquisition of Pharmacyclics
Acquisition adds Imbruvica®, one of the most promising new oncology therapies on the market, to AbbVie's portfolio.
Goodwin Biotechnology was Selected by Panacea Pharmaceuticals
Selected for a highly specialized vaccine fill / finish project.
BioClinica and Kinapse Partner to Accelerate RBM Implementation
Bolsters adoption of compass intelligent monitoring solution.
Halozyme, Ventana Team Up for CDx Development
The two companies have announced an agreement to co-develop a diagnostic assay that twins with Halozyme's new investigational drug.
Editas, Juno Collaborate on T Cell Genome Editing for Therapies
The two companies announced an exclusive collaboration to create chimeric antigen receptor (CAR) T cells and high-affinity T-cell receptor (TCR) cancer therapies.
Symphogen’s Antibody Mixtures Highlighted in Three Peer-Reviewed Journals
Pioneering and novel approach to Anti-EGFR and Pan-HER antibodies validated in clinical and pre-clinical research papers.
TGAC Awarded £150k to Help Boost Science Innovation
The funding will support three data-driven projects to advance bioinformatics tools from concept to commercialization for research and clinical use.
Biocartis and Fast-track Diagnostics Sign Strategic Collaboration
Both Companies aim to develop a range of multiplex tests on the Biocartis Idylla™ system each detecting a range of infectious disease pathogens.
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Events
Genomics & Proteomics Research
28 May 2015
Genomics & Proteomics Research ...
International Conference on Ad
28 May 2015
International Conference on Ad ...
ISBC 5th International School
24 May 2015
ISBC 5th International School ...
German Pharmacovigilance Day
02 Jun 2015
German Pharmacovigilance Day ...

ePosters
Acoustophoretic microfluidic device for high throughput DNA sequencing
Dept. of Biomedical Engineering IIT Hyderabad

Multiphysics modelling for acoustic standing wave technology combined with micro-technology which can be used for manipulation and concentration on typical Lab-on-Chip devices for DNA sequencing.
Development of a Paper-Based Fluidic Device for Phosphorus Detection
Saginaw Valley State University (SVSU)

This poster displays the successful beginning stages of an innovative way to detect phosphorus in standing bodies of water by minimizing the quantity of chemicals used, reducing the cost of analysis instrumentation, allowing the potential for real-time monitoring, and producing consistent and reliable results.
Assessment of the efficiency of encapsulation of a fluorescent drug using Nanoparticle Tracking Analysis
Malvern Instruments Ltd

This poster outlines an example where the methodology of Nanoparticle Tracking Analysis (NTA) is used to characterise nanoparticles for drug delivery purposes.
Single Cell Whole Genome Amplification
GE Global Research

The analysis of genomes at the single cell level offers unprecedented biological insights in diverse fields such as cancer research, immunology & microbiology. This poster discusses the a technology for amplification of genomic DNA form a single cell, that provides utmost sensitivity, accuracy & robustness. GE Healthcare Life Sciences had previously developed method of multiple strand displacement amplification (MDA) by Phi29 DNA polymerase
The Prestwick Chemical Library (R), A Valuable Tool for Screening
1. Prestwick Chemical, 220 Blvd Gonthier d'Andernach, 67400 Strasbourg-Illkirch, FRANCE 2. University of Strasbourg, Therapeuthic Innovation Laboratory, UMR7200 CNRS, Faculty of Pharmacy, 74 route du

The Prestwick Chemical Library® (PCL) is Prestwick’s flagship product dedicated to screening. It is a collection of 1280 molecules comprising 100% approved drugs (FDA, EMEA and other agencies) selected for their high chemical and pharmacological diversity. The PCL was designed to reduce the risk of "low quality" hits and therefore the cost of the initial screening, and appears to be an efficient smart library for hit discovery. The PCL comes with an extended fully-annotated database.
System-Specific Periodicity in qPCR Data and its Impact on Quantitation
1Dept. of Chemistry, Vanderbilt Univ., Nashville, TN USA 37235; 2 BTU Cottbus-Senftenberg, Senftenberg, Germany; 3 Dept. of Andrology, Univ. Hospital Hamburg-Eppendorf, Germany

In some commercial qPCR instruments, the fluorescence signal shows reaction-to-reaction periodicity in all cycles, and this translates into periodicity in threshold-based Cq markers.
Bovine RNA-seq data analysis of liver and pituitary gland
(1) Functional Genomics Lab. Faculty of Biology and Environmental Protection, Nicolaus Copernicus University, Torun, Poland, (2) Interdisciplinary Centre of Modern Technology, Nicolaus Copernicus Uni

Two key applications of RNA-seq i.e., i) transcriptome read mapping to a reference genome and ii) SNP detections were investigated to analysis of bovine liver and pituitary gland transcriptome. Here, we have presented ONLY the obtained results of bovine pituitary gland.
A proteomic analysis of p27kip1-binding proteins reveals a putative role in transcription regulation through RNA polymerase II interaction
1.-Department of Cell Biology, Immunology and Neurosciences, University of Barcelona-IDIBAPS, Barcelona, Spain 2.-INSERM UMR1037-Cancer Research Center of Tolouse, Universite de Tolouse, CNRS ERL5294

A proteomic analysis of p27kip1-binding proteins reveals a putative role in transcription regulation through RNA polymerase II interaction
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
TriLink BioTechnologies

We describe an optimized workflow which suppresses adapter dimers, works with low RNA input and eliminates the need for a gel purification step.
Whole Transcriptome RNA-SEQ with Ion Torrent Platform: FFPE, Fresh LCM and FFPE LCM Samples. Increasingly Difficult
1Pisa Science Founda:on, Pisa; Italy 2Department of Pathology, Pisa University Hospital, Pisa, Italy

We developed a high performance method to analyze the whole transcriptome of our FFPE samples, obtaining a very high number of reads (78,186,377 usable reads) perfectly comparable with samples with a large amount of RNA such as samples obtained from cells or fresh tissues.
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Application Notes
Assessing Product Stability During Transportation Using A Rotational Rheometer
Malvern Instruments Limited

This note discusses a simple rheological test for assessing product stability during transportation.
Dependance of Viscosity and Foam Consistency on Gas Volume Fraction
Malvern Instruments Limited

This note describes an empirical method for correlating foam rheology with gas volume fraction.
Predicting the Compounding Performance of Pressure Sensitive Adhesives (PSA’s)
Malvern Instruments Limited

This note discusses a method for assessing pump-ability and mix-ability of Pressure Sensitive Adhesives during manufacture.
Structural Elucidation of Dextrans and other Polysaccharides using OMNISEC Multi- Detection GPC
Malvern Instruments Limited

A series of dextran samples ranging in molecular weight from about 1– 650 kDa are characterized using OMNISEC. Structural comparisons to other polysaccharides, gum arabic and pectin are presented.
Evaluating Non-linear Viscoelastic Effects Using Normal Force Measurements on a Rotational Rheometer
Malvern Instruments Limited

This note discusses how non-linear viscoelastic effects can be evaluated using normal force measurements on a rotational rheometer.
Effect of Droplet Concentration on Emulsion Viscosity
Malvern Instruments Limited

This note discusses how rotational rheometry can be used to evaluate the impact of droplet concentration on emulsion viscosity
Predicting the Stability of Dispersions with a Yield Stress
Malvern Instruments Limited

This application note shows methodology and data for evaluating the stability of two shower gel (bodywash) products against their capability to suspend bubbles as a product requirement.
Characterizing Opthalmic Viscosurgical Devices (OVDs) Using A Aotational Rheometer
Malvern Instruments Limited

This application note discusses the methodology and results for the rheological characterization of Opthalmic Viscosurgical Devices (OVDs) according to the International Standard ISO15798:2013
Detecting the Presence of Anomolous Large Particles Within Powders Using Laser Diffraction Particle Size Analysis
Malvern Instruments Limited

In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials dosed with large particles and to detect those large, anomalous particles.
Measuring Small Quantities of Dry Powder Using the Aero S and Mastersizer 3000
Malvern Instruments Limited

In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials with good reproducibility and illustrating the dispersion abilities of the Aero S.
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