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Webcasts
Transporter Knockout Cell Lines in Preclincal Toxicology Assays and ServicesTransporter Knockout Cell Lines in Preclincal Toxicology Assays and Services
Join this webinar to learn how advanced ADME and toxicology services can help in the efficient development of drugs.
LC-High Resolution-MS in Clinical Labs: A Step Forward for TDM and MetabotypingLC-High Resolution-MS in Clinical Labs: A Step Forward for TDM and Metabotyping
Bertrand Rochat, Centre Hospitalier Universitaire Vaudois, speaking at Clinical Applications of Mass Spectrometry.

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
High Throughput Screening (HTS) Market by Technology, Applications, and End Users - Forecast to 2018
MarketsandMarkets

Technological advancements and flourishing outsourcing industry likely to propel the growth of the global high throughput screening market. In this report, the global high throughput screening market has been segmented on the basis of technology, products, applications, end users, and geography.
Chromatography Resin Market by Application, Techniques & Type - Trends & Forecast to 2018
MarketsandMarkets

The chromatography resin market is expected to grow at a decent pace during the coming decade driven by its increasing application in monoclonal antibody production and food analytics.
Chromatography Accessories and Consumables Market by Types, Technology & End-users - Trends & Global Forecasts to 2018
MarketsandMarkets

The chromatography accessories and consumables market demands significant investments in R&D in order to constantly come up with new and innovative products and technologies.
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Scientific News
Characterizing the Micro-Mechanical Properties of Soft Materials, Tissues and Cells
Ernst Breel of Optics11 discusses the current problems with characterizing the mechanical properties of soft materials, focusing on how the company's Piuma Nanoindenter can assist researchers.
Gene Variant Linked to Smoking Longer, Getting Lung Cancer Sooner
Smokers with a particular variation in a nicotine receptor gene were more likely to continue smoking for four years.
VTT Printed a Morphine Test on Paper
Company use antibodies as morphine sensing molecules when creating this morphine test.
Scientists Discover Protein That Boosts Immunity to Viruses and Cancer
Researchers now developing a gene therapy designed to boost the infection-fighting cells.
Kimchi-based Preservative Used in Cosmetics is Not So Natural
Scientists report that kimchi-based preservative marketed as “all-natural” contains synthetic ingredients.
Novel Nanoparticles Could Save Soldiers’ Lives After Explosions
Researchers paired clot-promoting nanoparticles with a corticosteroid that stops inflammation.
Paternal Sperm May Hold Clues to Autism
Tags on DNA from fathers’ sperm linked to children’s autism symptoms.
New Transitional Stem Cells Discovered
New stem cells are easier to manipulate, could help future research on reproductive problems.
NIH Study Finds Genetic Link for Rare Intestinal Cancer
Researchers recommend screening for people with family history.
Potential For Prediction Of Progression For Early Form Of Breast Cancer
Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.
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Business News
Pittcon 2015 Informatics Wrap-Up
Technology Continues to Impact the Lab; Pittcon Focuses on Workflows, Integration, Meta Data Management and Accelerating Innovation
Changing Phase of Biomarkers
Discover the current scenario and changing business models of the biomarkers field.
ASTM Standard will Aid Laboratories in Testing for Dissolved Gases in Water
An “effective and standardized” approach to testing for dissolved gases such as methane and ethane.
Long Term Clinical Data from PISCES Stroke Trial
Long term data continue to show good safety profile and evidence of sustained improvements in neurological status and limb function.
Watson-Marlow Fluid Technology Group Acquires ASEPCO Corporation
Company strengthens its biopharmaceutical offering through the acquisition of Asepco.
PPD and SNBL Complete Joint Venture
Joint venture to provide Japanese clinical development services and additional collaborations.
RainDance Technologies Extends Global Commercial Reach
BioTech-Europe, Diatech, Labgene Scientific, and Neo-Science embrace company’s award-winning droplet technology platform to meet growing demand for liquid biopsy research applications.
TxCell Strengthens its Board of Directors
Company has appointed Dr. David Solomon to board and as Chair of sub-committee.
Isarna Initiates First-in-Human Phase I Trial for ISTH0036
Phase I trial designed to evaluate the safety and long-term tolerability of ISTH0036 in patients with advanced glaucoma.
LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch
Company will collaborate with beta testers to generate test data sets.
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Events
Pharmaconex 2015
18 Apr 2015
Pharmaconex 2015 ...
8th Annual Proteins & Antibodi
20 Apr 2015
8th Annual Proteins & Antibodi ...
2nd Annual Peptides Congress
20 Apr 2015
2nd Annual Peptides Congress ...
3rd Annual Biosimilars & Biobe
20 Apr 2015
3rd Annual Biosimilars & Biobe ...

ePosters
A Microwave/Microfluidics Integrated Label-Free Detection and Content Sensing System for Point-of-Care Applications
University of Waterloo

This poster presents a droplet-based microfluidic device integrated with a microwave wave sensor, which is also a heater, for simultaneous sensing and heating of individual nanoliter-sized droplets.
LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Agilent Technologies, Diagnostics and Genomics Group

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.
An examination of specific cellular organelle-targeting nanotags using combined 3D Raman and SERS imaging
Renishaw plc,

We investigated the specific targeting of endoplasmic reticulum and trans-Golgi network in Chinese hamster ovarian cells using functionalised nanotags. The targeting was examined using the combined 3D SERS and Raman imaging method.

SOFT DEVICES FOR HEALTHCARE MONITORING APPLICATIONS
CETEMMSA

Printed Electronics allow the creation of new and innovative functionalized textile products, in the demanding and highly specialized world of Medical Devices. The main aim of this whole new sector is to produce wearable, conformable, flexible and low-cost textile-based devices bringing innovative solutions to different markets.
The Power Decoder simulator for the evaluation of pooled shRNA screen performance
GE Healthcare Dharmacon, Inc.

Power Decoder (written in R and Python) simulates shRNA pooled screening experiments in silico to allow for the estimation of a screen’s statistical power. Populations of shRNAs were engineered in such a way that the magnitude of depletion and enrichment was known, then using the negative binomial distribution, an in silico model was developed to successfully resemble data from an actual laboratory experiment.
Polymer Microarrays for Biomaterial Development
1. School of Chemistry, University of Edinburgh 2. Queen’s Medical Research Institute, University of Edinburgh 3. Scottish HPV Reference Laboratory, Royal Infirmary, Edinburgh 4. Centre for Virus Res

The application of polymer microarrays in the discovery of biocompatible and bioactive substrates. Progress towards biomaterial development for the treatment of SIRS (systemic inflammatory response syndrome), and improving cervical cytology.
Knockdown of long noncoding RNAs in breast cancer
GE Healthcare Dharmacon, Inc.

RNAi global collaboration study using Lincode siRNA in a primary screen of tumor and nontumor breast cell lines. Hundreds of lncRNAs are found to affect viability and cell morphology of breast cancer. Presented at Keystone Symposia on Long Noncoding RNAs: From Evolution to Function, Mar 15 - Mar 20, 2015.
TGA/IST16/GC/MS coupling : an advanced technique for LLDPE structure interpretation
1 SRA Instruments, 210 rue des Sources 69280 Marcy l'Etoile, France - 2 Université de Lyon, Univ. Lyon 1, CPE Lyon, CNRS UMR 5265, Laboratoire de Chimie Catalyse Polymères et Procédés (C2P2), Equipe

An innovative TGA/IST16/GC/MS coupling is presented.
DETERMINATION OF THE QUALITY OF ACTIVE INGREDIENTS IN PAIN KILLERS USING GC-MS
Jomo Kentyatta University of Agriculture and Technology (Kenya), and Foundation of Analytical Science and Technology in Africa (UK).

From this study, the pain killers sampled were found to have large error bars suggesting that there exist counterfeit drugs in the market. The brands mostly affected for analysis of acetaminophen were panadol, action, P500, P5500, elymol and neladol. The error bars for caffeine analysis were quite low indicating that all tablets either counterfeit or original maintained the same amount of this active ingredient.
DETERMINATION OF ESSENTIAL AND HEAVY METALS IN KENYAN HONEY BY ATOMIC ABSORPTION AND EMMISSION SPECTROSCOPY
Jomo Kenyatta University of Agriculture and Technology

Generally, honey samples recorded very low concentrations of As compared to the other heavy metals determined in this study. The highest concentration of As was recorded in honey sample from Nairobi with a value of 0.03±0.01 ppm. All the values recorded were within the KEBS permitted value of 0.5 ppm in food according to Kenya Bureaue of Standards, 1996.
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Application Notes
Characterizing Opthalmic Viscosurgical Devices (OVDs) Using A Aotational Rheometer
Malvern Instruments Limited

This application note discusses the methodology and results for the rheological characterization of Opthalmic Viscosurgical Devices (OVDs) according to the International Standard ISO15798:2013
Detecting the Presence of Anomolous Large Particles Within Powders Using Laser Diffraction Particle Size Analysis
Malvern Instruments Limited

In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials dosed with large particles and to detect those large, anomalous particles.
Measuring Small Quantities of Dry Powder Using the Aero S and Mastersizer 3000
Malvern Instruments Limited

In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials with good reproducibility and illustrating the dispersion abilities of the Aero S.
Measuring Small Volumes of Nanoparticles Using the Mastersizer 3000 and Hydro SV
Malvern Instruments Limited

This application note discusses the measurement of two nano-sized pigment samples using the Mastersizer 3000 and Hydro SV, highlighting the capability of the technique in resolving small differences in the particle size of the samples.
Aseptic Identification of Polysorbates using Handheld Raman
Rigaku Raman Technologies

As polysorbates are reactive to light and air, packaging is usually in thick, dark, amber bottles. This makes the identification process more difficult, as opening the container could compromise the sterility and quality of these materials. Handheld Raman is capable of identifying these materials without any sampling or preparation.
Herbal Materials and Natural Foods Analysis with Handheld Raman
Rigaku Raman Technologies

Dietary supplement manufacturers are required to use at least one appropriate test method to verify the identity of any component or excipient that is used in the manufacturing of a dietary supplement, as well as confirmation of identity of the product.
Cell Culture Media Identification In Biopharmaceuticals With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of cell culture media using Raman analysis.
Drug Product Identification Using Handheld Raman
Rigaku Raman Technologies

Handheld Raman spectroscopy is well accepted as a technique for raw material and excipient identification within the pharmaceutical industry. Using the correct Raman excitation wavelength can extend its capabilities into the areas of drug substance and drug product identification.
Pharmaceutical Excipients Identification With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of pharmaceutical excipients using Raman analysis.
Rapid Detection of Counterfeit and Substandard Medicines with Handheld Raman
Rigaku Raman Technologies

This application note discusses counterfeit screening using Raman analysis.
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