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Webcasts
Setting up a Scalable Bioinformatics Infrastructure for High-Throughput BiologySetting up a Scalable Bioinformatics Infrastructure for High-Throughput Biology
Dr Sven Nahnsen, University of Tuebingen, presenting a free of charge Technology Networks' webinar.
Photocontrolled Polymerizations in Flow: Next Generation Material SynthesisPhotocontrolled Polymerizations in Flow: Next Generation Material Synthesis
Thomas Junkers, Hasselt University, speaking at Flow Chemistry India 2015

Market Reports
High Throughput Assay Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on high throughput flow cytometry (HT flow) screening carried out in December 2014.
Mobile Technology In The Lab Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on the use of mobile technology to monitor and control of lab instruments and automated systems carried out in April 2015.
Epigenetic Proteins & Reagents Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on epigenetic proteins and reagents carried out in March 2015.
3D Spheroid Culture Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on three dimensional (3D) spheroid culture carried out in May 2015.
Critical Care Therapeutics in Major Developed Markets to 2020
GBI Research

The report provides in-depth analysis of the critical care market in the US, UK, France, Germany, Italy, Spain, Japan and Canada with an estimation of market size for 2013, along with market forecasts to 2020.
Apheresis Market, Applications, Devices & Disposables - Forecasts to 2017
MarketsandMarkets

The research report categorizes this market into procedure, application, technology, product type and end-user. All these markets are broken down into segments and sub-segments, providing exhaustive value analysis for 2010, 2011 and 2012, as well as forecast up to 2017.
Inherited Orphan Blood Disorders Therapeutics Market to 2019
GBI Research

The report provides insights into the up-and-coming trends of a portion of the inherited orphan blood disorder pharmaceutical market by examining sickle cell anemia, thalassemia and Hereditary Angioedema (HAE) in seven major markets.
Global Molecular Cytogenetics Market 2014-2018
Technavio

This report covers the present scenario and the growth prospects of the Global Molecular Cytogenetics market for the period 2014-2018.
Tissue Diagnostics Market by Technology, Disease, Product, End-Users & Region - Trends & Forecast to 2018
MarketsandMarkets

The report provides qualitative insights about key market shares, growth rates, and market drivers for all important sub-segments. It maps the market sizes and growth rates of each sub-segment and identifies the segments poised for rapid growth in each of the 20 geographic and regional segments.
Digital Pathology Market by Slide Scanners, Analytics, Delivery Modes & by Whole Slide Image Storage - Global Forecasts & Trends to 2018
MarketsandMarkets

The global digital pathology market was valued at an estimated $250.2 million in 2013 and is expected to grow at a CAGR of 11.8%, to reach an estimated $437 million by 2018.
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Scientific News
Health Risks of Saturated Fats Aggravated by Immune Response
Research shows that the presence of saturated fats resulted in monocytes migrating into the tissues of vital organs.
NIH Study Finds Calorie Restriction Lowers Some Risk Factors for Age-Related Diseases
Two-year trial did not produce expected metabolic changes, but influenced other life span markers.
Immunotherapy Agent Benefits Patients with Drug-Resistant Multiple Myeloma in First Human Trial
Daratumumab proved generally safe in patients, even at the highest doses.
Low-level Arsenic Exposure Before Birth Associated with Early Puberty in Female Mice
Study examine whether low-dose arsenic exposure could have similar health outcomes in humans.
Inciting an Immune Attack On Cancer Cells
A new minimally invasive vaccine that combines cancer cells and immune-enhancing factors could be used clinically to launch a destructive attack on tumors.
‘Mutation-Tracking’ Blood Test for Breast Cancer
Scientists have developed a blood test for breast cancer able to identify which patients will suffer a relapse after treatment, months before tumours are visible on hospital scans.
Cellular Contamination Pathway for Heavy Elements Identified
Berkeley Lab scientists find that an iron-binding protein can transport actinides into cells.
Intensity of Desert Storms May Affect Ocean Phytoplankton
MIT study finds phytoplankton are extremely sensitive to changing levels of desert dust.
Common ‘Heart Attack’ Blood Test May Predict Future Hypertension
Small rises in troponin levels may have value as markers for subclinical heart damage and high blood pressure.
LaVision BioTec Reports on the Neuro Research on the Human Brain After Trauma
Company reports on the work of Dr Ali Ertürk from the Institute for Stroke and Dementia Research at LMU Munich.
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Business News
Horizon and Redx Sign Cancer Research Collaboration
Collaboration to progress Redx Pharma plc’s novel pan-RAF inhibitor program towards out-licensing.
Dr John Hutchison Joins Autifony Therapeutics as Chief Medical Officer
Dr Hutchison brings a wealth of experience of clinical drug development in both big pharma and the biotech sector.
LINK Strengthens Presence in Switzerland with Distribution Agreement
Link Technologies appoints Swiss company Chemie Brunschwig AG as first partner in Europe.
NIH Grants Seek Best Ways To Combine Genomic Information and EHRs
Researchers seek to better understand genomic basis of disease, provide tailored care to patients.
EU Approval For Tafinlar® and Mekinist®
Novartis have announced that the European Commission has approved the combination of Tafinlar® (dabrafenib) and Mekinist® (trametinib) for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.
Novartis, Amgen Partner
The companies plan to co-develop and co-commercialize a BACE inhibitor program in Alzheimer's Disease (AD); Novartis' oral therapy CNP520 will be the lead molecule.
Adaptimmune Expands Trial of T-cell Therapy for Synovial Sarcoma
The company have announced that the first patient has been dosed in its expanded Phase I/II trial of its affinity enhanced T-cell receptor (TCR) therapeutic targeting the NY-ESO-1 cancer antigen in synovial sarcoma patients.
Cancer Research UK and Linguamatics Collaborate
Collaboration to improve characterization of cancer patient data for precision medicine.
Optibrium Appoints Head of North American Operations to Support Growing Demand
Appointment marks the opening of new office in Cambridge, MA.
Bristol-Myers Squibb and Promedior Enters into Agreement
Agreement providing exclusive right to acquire Promedior, Inc. and its novel PRM-151 in development for fibrotic diseases.
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Events
26th Congress of the Internati
31 Aug 2015
26th Congress of the Internati ...
Mobile in Clinical Trials
09 Sep 2015
Mobile in Clinical Trials ...
Setting up a Scalable Bioinfor
21 Jul 2015
Setting up a Scalable Bioinfor ...
Metabolism in Cancer & Stromal
08 Sep 2015
Metabolism in Cancer & Stromal ...

ePosters
Tools for studying and using small RNAs: from pathways to functions to therapies
Cold Spring Harbor Laboratory, Watson School of Biological Sciences

This poster provides an overview of the tools that have been developed to understand the functions of small RNAs and, conversely, the use of small RNAs as tools. Tools that are based on small RNAs have been exploited to investigate gene function in cultured cells and in living animals. Small RNA biogenesis, discovery and functional roles are explored in detail. Screening approaches to functional genomics, in vivo methods and potential therapeutic applications are discussed.
An HTS-Compatible Plate For Highly Miniaturized Cultures Of Primary Human Bronchial Epithelial Cells At Air-Liquid Interface
1BellBrook Labs, Madison, WI, USA 2UAB Cystic Fibrosis Research Center, Birmingham, AL, USA

Primary human bronchial epithelial cells (HBE) cultured at air liquid interface (ALI) exhibit striking similarity to the in vivo situation, including both tissue architecture and ion channel functionality. Cultures of this type serve as a gold standard for predicting therapeutic activity in airway diseases such as cystic fibrosis.
Increasing gene editing efficiencies in eukaryotic cell lines by selection of appropriate CRISPR-Cas9 reagents
GE Healthcare Dharmacon, Inc.

Overview of various CRISPR-Cas9 reagents to provide the highest efficiency of gene editing in your experiments.
Knockdown of p53 by Accell self-delivering siRNA causes inhibition of p53-dependent DNA damage response in IMR-32 neuroblastoma cell line and β-amyloid toxicity in rat cortical neurons
GE Healthcare Dharmacon, Inc.

Here we describe how application of Accell siRNA enabled the development of a high content screening assay in IMR-32 neuroblastoma cells and a whole culture cell viability assay in primary rat cortical neurons.
An Efficient Method for the Incorporation of Molecular Probes at Multiple/Specific sites in RNA: Levulinyl Protection for 2'-ACE ® , 5'-Silyl Oligoribonucleotide Synthesis
GE Healthcare Dharmacon, Inc.

A unique method that uses a levulinate ester as a protecting group to introduce conjugates or molecular probes to virtually any location in a synthetic RNA molecule is discussed. The Levulinyl protecting group is stable in RNA synthesis conditions and can be removed without affecting the other parts of the synthesized RNA. We show the capabilities of this approach with three high-complexity synthesis examples.
Acoustophoretic microfluidic device for high throughput DNA sequencing
Dept. of Biomedical Engineering IIT Hyderabad

Multiphysics modelling for acoustic standing wave technology combined with micro-technology which can be used for manipulation and concentration on typical Lab-on-Chip devices for DNA sequencing.
Development of a Paper-Based Fluidic Device for Phosphorus Detection
Saginaw Valley State University (SVSU)

This poster displays the successful beginning stages of an innovative way to detect phosphorus in standing bodies of water by minimizing the quantity of chemicals used, reducing the cost of analysis instrumentation, allowing the potential for real-time monitoring, and producing consistent and reliable results.
Assessment of the efficiency of encapsulation of a fluorescent drug using Nanoparticle Tracking Analysis
Malvern Instruments Ltd

This poster outlines an example where the methodology of Nanoparticle Tracking Analysis (NTA) is used to characterise nanoparticles for drug delivery purposes.
Single Cell Whole Genome Amplification
GE Global Research

The analysis of genomes at the single cell level offers unprecedented biological insights in diverse fields such as cancer research, immunology & microbiology. This poster discusses the a technology for amplification of genomic DNA form a single cell, that provides utmost sensitivity, accuracy & robustness. GE Healthcare Life Sciences had previously developed method of multiple strand displacement amplification (MDA) by Phi29 DNA polymerase
The Prestwick Chemical Library (R), A Valuable Tool for Screening
1. Prestwick Chemical, 220 Blvd Gonthier d'Andernach, 67400 Strasbourg-Illkirch, FRANCE 2. University of Strasbourg, Therapeuthic Innovation Laboratory, UMR7200 CNRS, Faculty of Pharmacy, 74 route du

The Prestwick Chemical Library® (PCL) is Prestwick’s flagship product dedicated to screening. It is a collection of 1280 molecules comprising 100% approved drugs (FDA, EMEA and other agencies) selected for their high chemical and pharmacological diversity. The PCL was designed to reduce the risk of "low quality" hits and therefore the cost of the initial screening, and appears to be an efficient smart library for hit discovery. The PCL comes with an extended fully-annotated database.
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Application Notes
How to Maximize Absolute Molecular Weight Measurement Accuracy: Synthetic Polymers
Malvern Instruments Limited


Determining Cure Profile and Post-Cure Shrinkage of Photopolymers Using UV Accessory on a Rotational Rheometer
Malvern Instruments Limited


Is Your Sample Dispersing or Milling? Hydro Sight’s In-Line Insight
Malvern Instruments Limited


Characterization of Protein Aggregates in Suspension and on a Filter Membrane by Morphologically-Directed Raman Spectroscopy
Malvern Instruments Limited


Exploring the Effect of Carbon Microstructure on Lithium-Ion Battery Performance
Malvern Instruments Limited


Investigation of Cell Migration using a High Density Cell Exclusion Assay and Automated Microplate Imager
BioTek Instruments

This application note investigates the use of high density cell exclusion assays for examination of cell migration.
Chromatrap® – Targeting the Epigenetic Landscape Alongside Low Abundant Transcription Factor Recruitment
chromatrap

This application note demonstrates the sensitivity, selectivity and reproducibility of solid phase Chromatrap®, as an assay for Chromatin IP from low cell numbers.
Real-time Monitoring of Genetically Encoded Redox Probes in Mammalian Cell Monolayers
BMG Labtech

In this application note we show that the PHERAstar FS reader enables roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.
Blood Cell Analysis with the Moxi Z
orflo

This application note discusses how Moxi Z can generate important metrics from blood samples for non-clinical analysis including red blood cell (RBC) counts, mean corpuscular volume (MCV), white blood cell (WBC) total counts and peripheral blood mononuclear cell (PBMC) size distributions and counts.
Whole-Mount Slide Imaging in Traumatic Brain Injury Research
hurron digital pathology

This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.
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