Corporate Banner
Satellite Banner
Automation & Microfluidics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Invitrogen Develops new Technology to Promote Safer Stem Cell Therapies

Published: Thursday, May 14, 2009
Last Updated: Thursday, May 14, 2009
Bookmark and Share
Dynabeads’ solution separates undifferentiated stem cells from differentiated cells to support translational research.

Invitrogen, a division of Life Technologies, has announced a new technology to enable the development of safer stem cell therapies. Dynabeads’ SSEA-4 addresses a key challenge in translational research, by separating undifferentiated stem cells from those that are differentiated.

Scientists from Invitrogen and the Buck Institute for Age Research, located in Novato, California, collaborated in developing this solution that depletes greater than 99 % of undifferentiated human embryonic stem cells from differentiated populations. They are presenting data on this new technology at the International Society for Cellular Therapy Meeting in San Diego.

Human embryonic stem cell research is one of the fastest growing areas in cell biology. These cells have unlimited proliferative capacity and can differentiate into multiple types, providing an infinite resource for many potential translational medicine applications.

A key issue for translational stem cell researchers is the ability to reliably identify and isolate undifferentiated hESCs, which are not considered as suitable for transplantation as those which are differentiated, because of the potential of unregulated cell growth. Their objective is to obtain pure and homogenous cell populations, which will help to ensure the safe development and manufacturing of therapeutics.

Dynabeads SSEA-4 achieves this by utilizing magnetic beads that latch onto a common marker on embryonic and induced pluripotent stem cells, removing them from a culture in less than 45 minutes. This leaves behind highly pure and differentiated cells that are unaffected by the Process.

Paul Pickering, General Manager of Invitrogen Cell Therapy Systems Business at Life Technologies said, “Dynabeads SSEA-4 is an innovative and highly effective solution that addresses one of the key challenges in the development of safer stem cell therapies. It was made possible through the collaboration of several technologies and business groups from different parts of the company coming together to offer a single solution to a problem faced by many of our stem cell customers.”

Xianmin Zeng, Ph.D., Associate Professor, Buck Institute, “Using Dynabeads SSEA-4, we are able to deplete greater than 99% of pluripotent cells in neural cell populations derived from pluripotent cells, which are likely targets for transplant therapy for neurodegenerative disorders.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Invitrogen Awarded $970K Contract by U.S. Department of Defense
Invitrogen has been awarded to produce and validate protein microarrays to biothreat agents.
Friday, January 13, 2006
Scientific News
Lab-on-a-Stick: Miniaturised Clinical Testing For Fast Detection Of Antibiotic Resistance
A portable power-free test for the rapid detection of bacterial resistance to antibiotics has been developed by academics at Loughborough University and the University of Reading.
Breast Cancer Cells Found To Switch Molecular Characteristics
Spontaneous interconversion between HER2-positive and HER2-negative states could contribute to progression, treatment resistance in breast cancer.
Measuring Chemistry on a Chip
Researchers developing chemical sensor chip for sample analysis in a lab or monitoring air and water quality in the field.
Automating Genetic Analysis
Researchers are looking to have computers help perform genetic analysis when scientists study a patient's genome to diagnose a disease.
DNA Condensation on a Chip
Carriers of genetic information packed together on a biochip like in nature.
Microchip Tech Improves Nanomaterial Safety Screening
Platform developed at UCLA uses lab-on-a-chip technology to predict how hazardous engineered nanomaterials might be.
Four Key Dynamics Driving Effective Outsourcing Decision Making for Lab Automation OEMs
Laboratory automation device manufacturers need to stay flexible in their outsourcing strategies because their make-versus-buy decisions may change over time.
How Cloud Connectivity Can Combat the Reproducibility Crisis
This infographic explains the reproducibility crisis, and how cloud connectivity can help overcome this problem.
'Fixing' Blood Vessel Cells To Diagnose Blood Clotting Disorders
A novel microfluidic device detects how endothelial cells that line vessels contribute to hemostasis.
Replicating the Connection Between Muscles and Nerves
New chip could help test drugs for ALS, other neuromuscular disorders.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!