Corporate Banner
Satellite Banner
Automation & Microfluidics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Droplets Formation and Merging in Two-Phase Flow Microfluidics

Published: Wednesday, July 20, 2011
Last Updated: Wednesday, July 20, 2011
Bookmark and Share
In this review article researchers from the University of Twente examine two-phase flow microfluidics and discuss recent innovations in microfabrication technologies.

Abstract

Two-phase flow microfluidics is emerging as a popular technology for a wide range of applications involving high throughput such as encapsulation, chemical synthesis and biochemical assays. Within this platform, the formation and merging of droplets inside an immiscible carrier fluid are two key procedures: (i) the emulsification step should lead to a very well controlled drop size (distribution); and (ii) the use of droplet as micro-reactors requires a reliable merging. A novel trend within this field is the use of additional active means of control besides the commonly used hydrodynamic manipulation. Electric fields are especially suitable for this, due to quantitative control over the amplitude and time dependence of the signals, and the flexibility in designing micro-electrode geometries. With this, the formation and merging of droplets can be achieved on-demand and with high precision. In this review on two-phase flow microfluidics, particular emphasis is given on these aspects. Also recent innovations in microfabrication technologies used for this purpose will be discussed.

The review article is published in the International Journal of Molecular Sciences and is free to access.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Integration of Enabling Methods for Automated Flow Preparation of Piperazine-2-Carboxamide
This work describes the application of automation to performing routine research tasks and how the application of remote monitoring can improve safety and efficiency.
Monday, May 19, 2014
All-Aqueous Multiphase Microfluidics
This paper reviews recent progress in the generation of all-aqueous emulsions and jets in microfluidic systems.
Thursday, February 06, 2014
Rapid Sub-attomole MicroRNA Detection on a Portable Microfluidic Chip
Researchers describe two key technologies to solve one of the major issues for point of care testing application.
Thursday, February 06, 2014
Microfluidics for Synthesis of Peptide-Based PET Tracers
Microfluidics is a very promising technology to meet the increased demand for peptide-based PET tracers.
Thursday, January 09, 2014
Microfluidic Separation of Live and Dead Yeast Cells using Reservoir-Based Dielectrophoresis
Cell separation is an essential step in biological research and has important applications in many areas such as environmental monitoring, food production, and pharmaceutical industry.
Friday, September 06, 2013
The Future of Microfluidics for Biomarker Detection
This article outlines the present status of microfluidics for biomarker detection.
Friday, September 06, 2013
Recent Progress in Lab-on-a-Chip Technology and Its Potential Application to Clinical Diagnoses
This study presents the construction of the lab-on-a-chip (LOC) system for the miniaturization of conventional laboratory apparatuses.
Friday, June 21, 2013
Electron Beam Fabrication of a Microfluidic Device for Studying Submicron-Scale Bacteria
This study presents an EBL and poly(dimethylsiloxane) (PDMS) [28] soft-lithography [29] protocol for the fabrication of a micro?uidic device for microbial studies.
Friday, April 26, 2013
Simple Filter Microchip for Rapid Separation of Plasma and Viruses from Whole Blood
Scientists have developed a disposable, pump-free, size exclusion–based filter microchip that can be used for plasma and virus separation from unprocessed whole blood samples in resource-constrained settings.
Wednesday, October 17, 2012
Microfluidics Based Phantoms of Superficial Vascular Network
This paper presents a method for fast prototyping of phantoms simulating a superficial vasculature network, based on microfluidics.
Wednesday, July 11, 2012
Density-Dependent Separation of Encapsulated Cells in a Microfluidic Channel
Cell encapsulation is a highly promising method for forming spherical cell bodies, which can mimic a multi-cellular in-vivo environment, for use as a three-dimensional cell culture model.
Wednesday, June 13, 2012
Sheathless Size-based Acoustic Particle Separation
The separation of particles or cells is critical for many biological and biomedical applications, including cell biology, diagnostics and therapeutics. This paper presents a novel sheathless SSAW based particle separation technique in a microfluidic channel.
Wednesday, May 16, 2012
Fluorescence Detection Methods for Microfluidic Droplet Platforms
This article reports the entire experimental process for detection of single cells and the mapping of mixing processes inside picoliter-volume droplets, including microfluidic chip fabrication, the optical setup and the process of droplet generation and detection.
Wednesday, May 16, 2012
Lipid-based Passivation in Nanofluidics
This study demonstrates the use of lipid bilayers as a passivation layer in nanofluidic networks, consisting of nanochannels and nanoslits, fabricated in fused silica.
Wednesday, May 16, 2012
Microfluidic Chip for Molecular Amplification of Influenza A RNA in Human Respiratory Specimens
This paper demonstrates a proof-of-concept microfluidic chip using clinical specimens collected over a two-year period from patients with suspected influenza.
Wednesday, April 11, 2012
Scientific News
The Changing Tides of the In Vitro Diagnostics Market
With the increasing focus in personalized medicine, diagnostics plays a crucial role in patient monitoring.
Capturing Cell Growth in 3-D
Spinout’s microfluidics device better models how cancer and other cells interact in the body.
Device May Detect Urinary Tract Infections Faster
A Lab-on-a-Disc platform developed by a German and Irish team of researchers dramatically cut the time to detect bacterial species that cause urinary tract infections -- a major cause of sepsis.
Automation Abound at AACC in Atlanta
Discover the latest breakthroughs, trends and products from the AACC Annual Meeting & Clinical Lab Expo.
Real-Time Data for Cancer Therapy
Biochemical sensor implanted at initial biopsy could allow doctors to better monitor and adjust cancer treatments.
Lab-on-a-Chip Offers Promise for TB and Asthma Patients
A device to mix liquids using ultrasonics is the first and most difficult component in a miniaturized system for low-cost analysis of sputum from patients with pulmonary diseases such as tuberculosis and asthma.
Paving the way to Better Ovarian Cancer Diagnosis
Aïcha BenTaieb will present her invention for automated identification of ovarian cancer’s many subtypes at an international conference this fall.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Futuristic Brain Probe Allows for Wireless Control of Neurons
NIH-funded scientists developed an ultra-thin, minimally invasive device for controlling brain cells with drugs and light.
Microfluidic Device Mixes And Matches DNA For Synthetic Biology
Researchers have developed a microfluidic device that quickly builds packages of DNA and delivers them into bacteria or yeast for further testing.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!