Corporate Banner
Satellite Banner
Automation & Microfluidics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

COWIN to Develop New Lab-On-A-Chip Pathogen Testing Range

Published: Wednesday, September 12, 2012
Last Updated: Wednesday, September 12, 2012
Bookmark and Share
COWIN, a European initiative to facilitate the take-up of advanced technologies, is now helping the commercialisation phase of a European project to develop a Lab-on-a-Chip.

The concept of a Lab-on-a-Chip has been around for many years but this project, which has been co-ordinated by IK4-Ikerlan, has brought together over a dozen different companies from around Europe to contribute the various technologies needed to make it a success. Called LabOnFoil, it is now at the stage of having three different products that are at the field testing phase.

"There is always a danger that projects such as this can lose their way when researchers find something interesting and go off on a tangent," explained Dr Jesus Ruano, International Project Manager at IK4-Ikerlan. "To ensure that we kept on track and on budget, we used a very strict Product Design model where the form and functionality of every component was clearly specified at the start. This meant that we were bringing together a jigsaw where each component was precisely defined and that made the co-ordination and timing much easier. Now that we have the technologies and product design sorted, COWIN is playing a vital role in helping identify which application areas to focus on and what are the key differentiators over existing solutions that will make LabOnFoil successful in each target market. For example, for some applications such as pathogen testing or in an Accident and Emergency Department being able to provide test result in 30 minutes rather than two days is a tremendous advantage but for routine blood tests it is not."

Each LabOnFoil kit is designed to identify a particular type of DNA. The Pathogen testing range can identify either Campylobacter or Salmonella. The Pathology range is tuned to blood proteins whose presence indicates that a treated cancer patient does not have a re-occurrence of cancer. The Environmental range detects the presence of red algae that gives an indication of climate change as this causes algae blooms when the sea temperature rises. These all use a special, credit card-sized, plastic test unit -- a LabCard, which is pre-loaded with the appropriate reagents for the test required. The LabCard is made from injection moulded plastic with the appropriate reservoirs and valves as required for a particular specific analysis. A thin film of plastic is laminated on top to seal in the reagents and this is flexible enough to act as valves when moving the liquids though the various stages such as Polymerase Chain Reaction (PCR) to replicate and increase the DNA.

The sample is sucked up into the supplied syringe where it mixes with the initial reagents and is then squirted into a reservoir on the LabCard. The LabCard is then inserted into a LabCardReader reader unit that automatically heats the LabCard, and opens and closes the valves on it to move the test sample through the preparation stages. The last step is to detect fluorescence that indicates the presence of the target DNA which can be in concentrations at low as a few femtograms of DNA in 30 minutes.

Geraldine Adrieux Gustin, the COWIN coordinator, added, "We are now helping IK4-Ikerlan plan the strategy to develop this product line further with multi-pathogen detection, handheld readers that plug into smartphones, new markets, etc. Potential customers are very excited as there are now real working products that can offer significant advantages over the existing gold standards by being faster, cheaper, simpler, or more sensitive as required."


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Paving the way to Better Ovarian Cancer Diagnosis
Aïcha BenTaieb will present her invention for automated identification of ovarian cancer’s many subtypes at an international conference this fall.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Futuristic Brain Probe Allows for Wireless Control of Neurons
NIH-funded scientists developed an ultra-thin, minimally invasive device for controlling brain cells with drugs and light.
Microfluidic Device Mixes And Matches DNA For Synthetic Biology
Researchers have developed a microfluidic device that quickly builds packages of DNA and delivers them into bacteria or yeast for further testing.
Artificial Pancreas Controls Diabetes
Scientists are reporting the development of an implantable “artificial pancreas” that continuously measures a person’s blood sugar, or glucose, level and can automatically release insulin as needed.
Major Step for Implantable Drug-Delivery Device
MIT spinout signs deal to commercialize microchips that release therapeutics inside the body.
Smart Insulin Patch Could Replace Painful Injections for Diabetes
A joint effort between diabetes doctors and biomedical engineers could revolutionize how people with diabetes keep their blood sugar levels in check.
The Secrets of Secretion
Researchers have hacked nature's blueprints to create a new technology that could have broad-reaching impact on drug delivery systems and self-healing and anti-fouling materials.
New Tool on Horizon for Surgeons Treating Cancer Patients
Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers.
Heartbeat on a Chip Could Improve Pharmaceutical Tests
A gravity-powered chip that can mimic a human heartbeat outside the body could advance pharmaceutical testing and open new possibilities in cell culture because it can mimic fundamental physical rhythms.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!