Corporate Banner
Satellite Banner
Automation & Microfluidics
Scientific Community
Become a Member | Sign in
Home>News>This Article

New DNA Cattle Test Beefs up Dairy and Meat Quality

Published: Wednesday, May 22, 2013
Last Updated: Wednesday, May 22, 2013
Bookmark and Share
A genomics technique developed at Cornell to improve corn can now be used to improve the quality of milk and meat.

A team led by Ikhide Imumorin, Cornell assistant professor of animal science, is the first to apply a new, inexpensive yet powerful genomics technique to cattle called genotyping-by-sequencing (GBS). The protocol contains only four basic steps from DNA to data, and Imumorin’s work demonstrated it generates enough markers to put cattle genomics on the fast track.

“Breeders are interested in cattle with traits such as high meat or milk quality, disease resistance and heat tolerance, but identifying the best animals means sorting through thousands of unique gene variants in the genome,” said Imumorin. “Until recently, the cost of genomics techniques has set too high a bar for breeders, and many cattle species, particularly those outside the United States and Europe found in Africa and Asia, were excluded from the genomics revolution.”

Using samples from 47 cattle from six breeds from the United States and Nigeria, Imumorin’s team used GBS to identify more than 50,000 genetic markers for genetic profiling. GBS was developed by Rob Elshire, researcher in the lab of Ed Buckler, a research geneticist with the U.S. Department of Agriculture (USDA) Agricultural Research Service and adjunct professor of plant breeding and genetics at Cornell.

The team’s analysis showed the markers were preferentially located in or near the gene-rich regions in the arms of the chromosome, making them well sited for tagging genes in genetic studies. The researchers also demonstrated that the markers accurately detect the relationships among the breeds.

“GBS democratizes genetic profiling, and our work shows its usefulness in livestock,” said Imumorin. “While a genetic profile could run $70 to $150 per individual using commercially available methods, GBS brings the cost down to around $40 a sample or less. It’s a very exciting time.”

Imumorin predicts that GBS will be deployed by breeders and geneticists scanning herds for superior breeding stock. He cited the example of how selection of bulls for use in breeding programs will be streamlined through GBS-driven genome analysis around the world without the steep cost of commercial SNP chips, the standard tool based on gene variants discovered in European cattle breeds and made into off-the-shelf genotyping chips.

“For example, a bull can have genes for superior milk production, but the only way to test that is to evaluate milk production in his daughters,” said Imumorin. “A bull will be at least five years old before two generations of his offspring can be evaluated, and that’s a long time for breeders to take care of a bull that may not make the final cut. These techniques hasten the day when a bull’s value can be assessed using genetics on its day of birth more cheaply than we can do now.”

The study was funded by Pfizer Animal Health (now Zoetis Inc.), the USDA National Institute of Food and Agriculture and USDA Federal Formula Hatch Funds appropriated to the Cornell University Agricultural Experiment Station.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Ingested Nanoparticles May Damage Liver
Although nanoparticles in food, sunscreen and other everyday products have many benefits, researchers from Cornell are finding that at certain doses, the particles might cause human organ damage.
Tuesday, August 12, 2014
Optical Traps on Chip Manipulate Many Molecules at Once
By shrinking the technology of an optical trap onto a single chip, Cornell physicists have created a device that can potentially reduce month-long experiments to days.
Wednesday, April 30, 2014
New Micro Water Sensor Can Aid Growers
Crop growers, wine grape and other fruit growers, food processors and even concrete makers all benefit from water sensors for accurate, steady and numerous moisture readings.
Monday, October 14, 2013
NIH-Funded Tissue Chips would Predict Drug Safety
Researchers from Cornell University will develop microphysiological modules to model the nervous, circulatory and gastrointestinal tract systems.
Friday, August 31, 2012
The Force is with us: GEDI Chip Sorts Prostate Cancer Cells
Geometrically Enhanced Differential Immunocapture chip identify and collect cancer cells from a patient's bloodstream.
Friday, June 29, 2012
Artificial Intestine Could Treat Children's Bowel Condition
A tiny 3-D collagen "scaffold" developed in a Cornell lab could prove a lifesaver for those who have lost parts of their intestine.
Monday, December 12, 2011
Microfluidic Devices for Circulating Tumor Cell Capture
The Kirby Research Group at Cornell University are attempting to use microfluidic devices to capture circulating tumor cells from prostate cancer patients, with a view towards preclinical evaluation of chemotherapeutic efficacy.
Tuesday, November 23, 2010
Scientific News
Discovery Provides New Opportunities for Chips
Scientists at the University of Twente's MESA+ research institute have developed a new manufacturing method to create three-dimensional nanostructures.
Penn Engineering Team Showcases ‘Eye-on-a-Chip’ Technology
These small plastic chips contain microfluidic channels, carefully designed so that human cells can grow in them in a way that simulates the three-dimensional environments they would normally inhabit in the body.
Miniaturizable Magnetic Resonance
Microscopic gem the key to new development in magnetic lab-on-a-chip technology.
Education and Expense: The Barriers to Mass Spectrometry in Clinical Laboratories?
Here we examine the perceived barriers to mass spec in clinical laboratories and explore the possible drivers behind the recent shift in uptake of the technology in clinical settings.
Chip-Based Technology Enables Reliable Direct Detection of Ebola Virus
Hybrid device integrates a microfluidic chip for sample preparation and an optofluidic chip for optical detection of individual molecules of viral RNA.
Stem Cell Research Hints at Evolution of Human Brain
Researchers at UC San Francisco have succeeded in mapping the genetic signature of a unique group of stem cells in the human brain that seem to generate most of the neurons in our massive cerebral cortex.
Developing a Breathalyzer-Type Low Blood Sugar Warning Device For Diabetes
A multidisciplinary team of researchers at Indiana University-Purdue University Indianapolis has been awarded a $738,000 National Science Foundation grant to develop a breathalyzer-type device to detect the onset of hypoglycemia, or low blood sugar episodes, in people with diabetes.
Smartphone App to Monitor Serious Blood Disorder
A researcher from Florida Atlantic University has come up with a unique way to monitor sickle cell disease -- a serious blood disorder -- using a smart phone.
Preventing Crystallization to Improve Drug Efficiency
Esther Amstad and an international team of researchers have developed a method to increase the solubility of poorly soluble substances, such as many of the newly developed drugs.
‘Lab-on-a-Chip’ Technology Cuts Costs of Lab Tests
With ability to analyze minuscule amounts of fluid, Rutgers breakthrough could also promote central nervous system and joint research.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos