Corporate Banner
Satellite Banner
Automation & Microfluidics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Channel-Free Microfluidic Technology for Molecular Testing Developed

Published: Saturday, February 08, 2014
Last Updated: Thursday, February 27, 2014
Bookmark and Share
The Smart FilmCARD would be the first microfluidic device in the diagnostics industry with no channels included in its design.

Rheonix, Inc. has created a channel-free microfluidic device, the Rheonix Smart FilmCARD™. This breakthrough will significantly decrease the research, development and production costs of microfluidic solutions and allow sophisticated diagnostic tests to become more widely available. The Smart FilmCARD is capable of complex fluid manipulations with potential applications in research laboratories, genetic sequencing sample preparations and in vitro diagnostic (IVD) assays. 

The Smart FilmCARD is a groundbreaking evolution of Rheonix’s existing core technology, the Chemistry and Reagent Device (CARD®). The CARD runs samples through a fully integrated molecular assay without user intervention based upon Rheonix’s novel solvent lamination capabilities. Compared with the CARD technology, the Smart FilmCARD uses the deformed gasket wall to replace channels for fluidic network formation. The channel-free design permits controlled movement of fluids anywhere on the Smart FilmCARD while virtually eliminating dead-volume losses typical of channeled devices. Without channels, reagents can be packaged and stored easily on the device to allow more varied applications than are currently possible in the life sciences tools and IVD markets. 

“The capability to reliably package micro-liter volumes of reagents into a device and pump those reagents in a manner that is not limited by predefined fluid pathways opens Rheonix to diagnostic applications not previously envisioned, or possible,” said Peng Zhou, Ph.D., Rheonix chief scientific officer. “For the first time, we will be able to work with researchers and developers to design a device with the cost structure and function that enables subsidy-free adoption of advanced molecular technologies to facilitate widespread diagnosis of diseases such as drug-resistant tuberculosis, malaria, dengue fever, Chagas disease and other human afflictions that cause serious illness and death throughout the world.” 

The Smart FilmCARD enables Rheonix to address diverse market requirements that are too difficult to perform with existing systems, such as automated next-generation sequencing library sample preparation, low-cost infectious disease panel testing and point-of-care applications. It also enables Rheonix to serve markets requiring small-volume reagent management, onboard reagents and simpler testing procedures while dramatically lowering the complexity of manufacturing molecular devices. 

“Simply put, we see applications for this platform across the full spectrum of molecular analysis applications. This elegantly simple approach to fluidic handling has the ability to address market needs around the globe with functional utility in applications as diverse as next-generation sequencing preparations and point-of-care molecular diagnostics testing,” said Tony Eisenhut, Rheonix president. 

The Smart FilmCARD development efforts will continue within the newly formed Rheonix Innovation Center under the direction of Peng Zhou. Zhou holds 14 U.S. patents. “For a researcher, there is nothing more exciting than being given a blank canvas and the tools to create solutions for pressing problems. The Smart FilmCARD is this canvas, and we will explore a variety of applications free from constraints due to cost-of-goods-sold limitations,” Zhou said.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Rheonix to Pursue Rapid Zika Virus Diagnostic
Company to develop automated system for simultaneous Zika virus detection and confirmation.
Wednesday, April 20, 2016
Scientific News
Measuring Chemistry on a Chip
Researchers developing chemical sensor chip for sample analysis in a lab or monitoring air and water quality in the field.
Automating Genetic Analysis
Researchers are looking to have computers help perform genetic analysis when scientists study a patient's genome to diagnose a disease.
DNA Condensation on a Chip
Carriers of genetic information packed together on a biochip like in nature.
Microchip Tech Improves Nanomaterial Safety Screening
Platform developed at UCLA uses lab-on-a-chip technology to predict how hazardous engineered nanomaterials might be.
Four Key Dynamics Driving Effective Outsourcing Decision Making for Lab Automation OEMs
Laboratory automation device manufacturers need to stay flexible in their outsourcing strategies because their make-versus-buy decisions may change over time.
How Cloud Connectivity Can Combat the Reproducibility Crisis
This infographic explains the reproducibility crisis, and how cloud connectivity can help overcome this problem.
'Fixing' Blood Vessel Cells To Diagnose Blood Clotting Disorders
A novel microfluidic device detects how endothelial cells that line vessels contribute to hemostasis.
Replicating the Connection Between Muscles and Nerves
New chip could help test drugs for ALS, other neuromuscular disorders.
Lab-on-a-Chip to Detect Cancer and Diseases at the Nanoscale
IBM scientists will collaborate with the Icahn School of Medicine at Mt. Sinai to test on prostate cancer.
Diagnostic Thread - Weaving the Future?
Researchers have created diagnostic threads that could pave the way for next-gen implantable and wearable diagnostics.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!