Corporate Banner
Satellite Banner
Automation & Microfluidics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Kreatech Launches RNA ampULSe Amplification and Labeling Kits

Published: Tuesday, August 30, 2005
Last Updated: Wednesday, August 31, 2005
Bookmark and Share
Kreatech Biotechnology releases labeling kits for DNA microarray applications, designed to offer the ULS labeling molecule bound to a choice of fluorescent dye pairs

Kreatech Biotechnology has announced the release of labeling kits for DNA microarray applications, the RNA ampULSe Amplification and Labeling Kits.

The RNA ampULSe kit combines the technology obtained from a technology supply agreement with Ambion for their MessageAmp™ II aRNA amplification system, in conjunction with Kreatech’s proprietary Universal Linkage system (ULS™) labeling technology, to provide a series of complete RNA amplification and labeling kits for gene expression analysis.

These kits are designed to offer the ULS labeling molecule bound to a choice of fluorescent dye pairs that have been licensed by Kreatech including the leading dyes from GE Healthcare/Amersham (CyDyes™), and also a biotin kit, for use on Affymetrix GeneChip®.

The RNA ampULSe kit also includes Kreatech’s KREApure columns to purify the labeled aRNA which insures effective removal of unreacted ULS and higher recoveries of sample.

According to Brent Keller, General Manager of Kreatech USA/Vice President of Commercial Operations, “The RNA ampULSE product is the perfect combination of two successful and powerful technologies.”

He adds, “In using the direct, non-enzymatic ULS labeling technology the performance of the Ambion in vitro Transcription reaction is further enhanced since the end user can use natural unmodified nucleotides in the amplification step resulting in higher sample yields and a better representation of the transcriptome.”

“Since unmodified aRNA is more stable than aminoallyl modified aRNA, users have the opportunity to store or archive the unmodified aRNA and label as needed for later use in microarrays or other downstream assays”

Kreatech’s ULS technology relies on the special binding properties of transition metals, especially platinum, to form coordinative bonds with biomolecules by binding to specific sites on DNA, RNA and proteins.

In this way, ULS acts as relatively simple “molecular glue” for DNA, RNA and proteins. As a result of its versatility, customers have a choice of the molecular label attached to the ULS they can use to label the biomolecules of interest.

Kreatech currently commercializes labeling kits for aRNA labeling, arrayCGH labeling, and earlier this month introduced the PlatinumBright™ line of labeling kits for general nucleic acid labeling.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Gentel® Signs Supply and Marketing License Agreement
GenTel to market and sell the ULS labeling reagents under their brand name PANDEIA™ in diverse kit formats.
Wednesday, August 17, 2005
Scientific News
Microdroplet Reactors Mimic Living Systems
Researchers use microdroplets to study non-equilibrium reactions like those in living organisms.
Toxicity Testing With Cultured Liver Cells
Microreactor replaces animal testing.
Study Validates Analysis of Copy Number Variation in Miniaturized Reaction Volumes
Data shows that accurate and reproducible CNV results can be produced with IntelliQube using the Array Tape® consumable.
Spotlight on Acoustic Liquid Handling
Journal of Laboratory Automation special issue highlights how acoustic liquid handling enables breakthrough innovations.
Organs on Chips
Combining 3D cell culture with microfluidics, organs-on-chips could revolutionize toxicology testing for pharmaceuticals, foods, cosmetics, pesticides, and industrial chemicals.
Finding the Needle in a Microbial Haystack
After developing a novel investigational technology called PathoChip that can rapidly identify elusive microorganisms, a team of Penn Medicine researchers recently succeeded for the first time in identifying a pathogen in a patient sample, demonstrating the proof of principle that this technology can be used to identify pathogens in human disease.
Organ-on-a-Chip
In a step toward personalized drug testing, researchers coax human stem cells to form complex tissues.
Diagnosing Cancer from a Single Drop of Blood
What if a physician could effectively diagnose cancer from one drop of a patient’s blood?
Study Reveals Shared Behavior of Microbes And Electrons
Bacteria streaming through a lattice behave like electrons in a magnetic material.
Study Reveals Shared Behavior of Microbes and Electrons
Bacteria streaming through a lattice behave like electrons in a magnetic material.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!