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Caliper Life Sciences Aids the Sanger Institute's Protein Expression Project

Published: Wednesday, April 05, 2006
Last Updated: Wednesday, April 05, 2006
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The Wellcome Trust Sanger Institute has purchased the microfluidic-based LabChip® 90 Automated Electrophoresis System to quality control DNA and proteins.

Caliper Life Sciences, Inc. announced that the Wellcome Trust Sanger Institute has purchased the microfluidic-based LabChip® 90 Automated Electrophoresis System to quality control DNA and protein within its Atlas of Protein Expression project.

The goal of the project is to systematically study the way proteins are "expressed," or produced, in cells and tissues and to create a quality, information-rich database of protein expression profiles accessible to the worldwide research community.

The Sanger Institute uses Caliper's LabChip 90 system to generate quantitative sizing, concentration, and purity data for polymerase chain reaction (PCR) products, expressed proteins, and the antibodies used for immunohistochemistry experiments.

The ability to machine microfluidic chips that are inherently more reproducible than traditional slab gels, combined with the fact that the LabChip 90 system generates real-time electronic data suitable for inter-laboratory data sharing, makes the system a good match for the project's goals.

The system also allows researchers to process multiple experiments at the same time and generate multiple data views.

"We are consistently looking for tools that can save time and redundancy in our research process," said Michael Dyson, project leader, Wellcome Trust Sanger Institute. "For this leading-edge project, we need to deploy and integrate systems that reduce intensity of human effort and provide high quality data."


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