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DC microelectrode array for cell investigation
Marisa Rio1 , Sharanya Bola2, Salvatore Girardo3, Richard H. Funk2, Gerald Gerlach1

In order to mimic the endogenous dc electric field that cells experience in vivo, a microelectrode array was designed. Preliminary tests showed biocompatibility and promise to render further understanding of the cellular interaction with DC electric fields.

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A multi-resonances valveless micropump with high fluid transportation efficiency
Ming-Che Hsieh, Min-Fan Huang, and An-Bang Wang

A multi-resonances valveless micropump equipping with inlet/outlet elastic chambers of intendedly-designed stiffness was successfully realized to solve the low efficiency problem. Besides, a theoretical model based on Hydraulic-electrical-Analogy was also proposed to precisely predict its characteristics of dynamic behavior.

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Dry-mass sensing for microfluidics
T. Müller, D. A. White, and T. P. J. Knowles

The dry mass of analyte from microchannels is measured by means of spray-drying on an electromechanical sensor with nanogram sensitivity.

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A Microfluidic Device for Detection of Water Contamination from Hydraulic Fracturing
Leslie J. Loh, Gayan C. Bandara, Christopher A. Heist and Vincent T. Remcho

A paper-based microfluidic device was designed and optimized for the colorimetric detection of bromide in water. This work was developed in response to the waste management challenges and pollution risks of hydraulic fracturing wastewater. This device is suitable for distribution as a field test as it is portable, easy to use, inexpensive and can be packaged to extend shelf life.

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Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy
ANSHIKA NIKITA SINGH, MEGHNA BARUAH, NEETI SHARMA

The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.

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Identification of microRNA targets using microRNA modulation techniques and gene expression arrays
Emily M. Anderson, Maren Mayer, Kevin Sullivan, Barbara Robertson, Žaklina Strezoska, Annaleen Vermeulen, and Devin Leake

By examining the overlap of messages down-regulated by miRNA mimics and up-regulated by miRNA inhibitors, we robustly identify miRNA-regulated messages, many of which have canonical seed matches and some which are not identied by standard target prediction programs.

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Capillary Electrophoresis Coupled with Micro Free Flow Electrophoresis for High Speed Two Dimensional Separations of Biological Samples
Alexander C. Johnson, Michael T. Bowser

We propose using micro free flow electrophoresis (µFFE) as a solution to the under sampling problem.

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Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery
L.D. van Vliet1*, F. Gielen1, A. Sinha2, B.T. Koprowski3, J.B. Edel4, X.Niu5, A.J. deMello3, F. Hollfelder1, & J. Motschman2

To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).

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Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications
Daniel Czurratis*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.

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Showing Results 21 - 30 of 235
Scientific News
The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Biosensor Detects Molecules Linked to Cancer, Alzheimer's and Parkinson's
Novel biosensor has been proven capable of detecting molecules associated with neurodegenerative diseases and some types of cancer.
New Device Could Improve Cancer Detection
UBC researchers develop a microfluidic device to capture circulating tumor cells.
Gut Model HuMiX Works Like the Real Thing
Developed by scientists at the Luxembourg Centre for Systems Biology, the “Human Microbial Cross-talk” model is representative of the actual conditions and processes that occur within our intestines.
'Kidney on a Chip' Facilitates Safer Drug Dosing
University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.
AACR 2016: Cancer Immunotherapy and Beyond
At this year's meeting there was a palpable buzz around subjects ranging from microbiomics to the tumor microenvironment and cancer vaccines, big data to in vitro and in vivo modeling and drug delivery (to name just a few).
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Lab-on-a-Chip for Detecting Glucose
By integrating microfluidic chips with fiber optic biosensors, researchers in China are creating ultrasensitive lab-on-a-chip devices to detect glucose levels.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Soy Shows Promise as Natural Anti-Microbial Agent
Researchers from University of Guelph show that soy isoflavones and peptides could be used to reduce microbial contamination of food.
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