Corporate Banner
Satellite Banner
ADME Tox
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Advancing the Knowledge of Pharmaceutical Processes

Published: Wednesday, February 26, 2014
Last Updated: Wednesday, February 26, 2014
Bookmark and Share
Linkam Scientific Instruments report on the use of their stages in the study of pharmaceutical processes.

The School of Pharmacy and Life Sciences at the Robert Gordon University have been using Linkam systems to look at the behavior of drugs at varying temperatures. This relatively young university was awarded with the prestigious "The Sunday Times Best Modern University in the UK" in 2012 with the School of Pharmacy and Life Sciences being one of the key factors contributing to this recognition.

Dr Kerr Mathews, a lecturer in Pharmaceutics at the University since 2004, has focused a lot of time and effort in key interests in the area of drug delivery and formulation science. In particular, the research and development of solid and liquid drug delivery systems have been extensively undertaken.

Dr Matthews has used both a Linkam LTS stage and a FDCS stage to study the phase transitions of drugs, excipients and delivery systems as a function of temperature. He has found the equipment to be integral to his work. "We find this classic technique of qualitative analysis invaluable when used in conjunction with differential scanning calorimetry (DSC) or thermogravimetry (TGA), especially to corroborate assignment of phase transitions in solids or liquids."

He added that the ability to study the samples under polarized light is also of vital importance. "We also use the capabilities of a materials microscope fitted with cross-polarising filters in both transmitted and reflected light modes, to assess the degree of anisotropy in solid solutions, polymers and assorted dosage forms."

Lyophilisation is another application that is of particular interest to Dr. Matthews and his team. They have used the Linkam FDCS 196 stage to recreate low temperature conditions which are encountered during the pharmaceutical freeze drying process.

With the ever increasing cost of pharmaceutical products, the importance of research into the formulation and stability of drugs has never been higher. World renowned companies from all over the globe use such research to optimize the synthesis and storage of their products.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Breakthrough Flu Vaccine Inhibited by Pre-existing Antibodies
Universal truths – how existing antibodies are sabotaging the most promising new human flu vaccines.
Gene Therapy for Metabolic Liver Diseases
Researchers have tested gene therapy in pigs from hereditary tyrosinemia type 1, with corrected liver cells being transplanted into the diseased liver.
Testing Nanoparticle Drug Delivery in Dogs
Scientists have tested a nanoparticle drug delivery against bone cancer in dogs with promising results.
Targeting Autoimmunity
Researchers have developed a strategy to treat a rare autoimmune disease which could lead to treatments of other autoimmune diseases.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
Protein Nanocages Could Improve Drug Design and Delivery
HHMI scientists have designed and built 10 large protein icosahedra that are similar to viral capsids that carry viral DNA.
Development in Preventing Macular Degeneration
Following macular degeneration insight, promising drugs to prevent vision loss have been identified.
Improving Tumour Therapy with Nanoparticles
UHN nanoparticle called PEARLs is a promising utilisation of photo-thermal therapy for cancer treatment.
New Antidepressant Treatment Discovered
Scientists have demonstrated how gene therapy could lead to new treatments for depression.
Cellular Origin of Skin Cancer Identified
Scientists have identified ‘cell of origin’ in the most common form of skin cancer, and followed the process that leads to tumour growth.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!