Corporate Banner
Satellite Banner
ADME Tox
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

AstraZeneca, MRC Collaboration to Create New Centre for Early Drug Discovery

Published: Monday, March 31, 2014
Last Updated: Tuesday, April 01, 2014
Bookmark and Share
The Companies today announced the groundbreaking collaboration aimed at better understanding the mechanisms of human disease. The collaboration will see the creation of a joint research facility at AstraZeneca’s new R&D centre in Cambridge in the UK.

The AstraZeneca MRC UK Centre for Lead Discovery will sit within the new AstraZeneca site at the Cambridge Biomedical Campus, due to be completed in 2016. It will see world class MRC-supported researchers working side-by-side with scientists in AstraZeneca’s high throughput screening group, identifying new methods to better understand a range of diseases and potential treatment options.

As part of the collaboration, which will run for an initial period of five years, academic researchers will benefit from unprecedented access to over two million molecules in AstraZeneca’s compound library, as well as its state-of-the-art high throughput screening facilities at the new site.

Research proposals will be submitted to the MRC, which will independently assess and select the best scientific proposals from a broad range of therapy areas and diseases. The MRC will fund up to 15 screening projects per year to be carried out at the Centre for Lead Discovery.

AstraZeneca will have the first option to enter a negotiation to license any resulting drug discovery programmes of relevance to the company’s therapeutic areas of interest. If this option is not used, the academics can negotiate with other parties.

Menelas Pangalos, Executive Vice President, Innovative Medicines and Early Development at AstraZeneca, said: “This major strategic alliance with the MRC is the first of its kind. It will further AstraZeneca’s aim of creating a truly innovative and collaborative research environment at our new site in Cambridge, where our teams will work side by side with world leading MRC scientists. Through this collaboration AstraZeneca and the MRC will push the boundaries of science to accelerate drug discovery and the development of new medicines here in the UK.”

Professor Sir John Savill, Chief Executive of the MRC said: “This is a unique collaboration that will give MRC researchers unparalleled access to AstraZeneca’s state-of-the-art screening capabilities, world-leading infrastructure and an extensive, high quality compound library. The agreement demonstrates the MRC and AstraZeneca’s commitment to long term investment in UK infrastructure. It is an exciting move that will fast-track research that might not otherwise have been carried out, and will ultimately mean better treatments for patients.”

Science Minister David Willetts said: “AstraZeneca, one of the world’s largest pharmaceutical companies, has signalled a huge vote of confidence in our UK science base by selecting the MRC as their partner of choice for this exciting new collaboration. Forging these strong business and academic partnerships supports our Life Sciences Industrial Strategy and is vital in reinforcing the UK's reputation as a global leader in medical research."

Some initial projects may commence as early as 2015, based at AstraZeneca’s existing research facilities.  


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

A Fundamental Protection Mechanism Against Formalin In Mammals is Revealed
Formaldehyde, or formalin, is well known to all of us as a common chemical used in many industrial processes and also as a preservative, remarkably we also produce formaldehyde in our bodies.
Wednesday, September 30, 2015
Study Leads to Alzheimer's Breakthrough
Researchers at the Medical Research Council Toxicology Unit have used an orally-administered compound to block a major pathway leading to brain cell death in mice, preventing neurodegeneration.
Thursday, October 10, 2013
A Declaration of Openness in Using Animals in Research
The MRC and other members of the research sector have signed a declaration on transparency in animal research.
Monday, October 22, 2012
Brain Chemical Finding could Open Door to new Schizophrenia Drugs
New research has linked psychosis with an abnormal relationship between two signalling chemicals in the brain.
Friday, October 01, 2010
Medical Research Council Technology and Pharmidex Announce Drug Discovery Collaboration
Pharmidex to provide all in vivo ADME/PK drug discovery support to the MRCT in 2010.
Thursday, April 15, 2010
Health Protection Agency Launches new Research Centre for Studying Nanotoxicology
The Agency is collaborating with universities and the MRC Toxicology Unit to study the possible health effects of human exposure to nanoparticles.
Friday, July 25, 2008
Scientific News
Breakthrough Flu Vaccine Inhibited by Pre-existing Antibodies
Universal truths – how existing antibodies are sabotaging the most promising new human flu vaccines.
Testing Nanoparticle Drug Delivery in Dogs
Scientists have tested a nanoparticle drug delivery against bone cancer in dogs with promising results.
Targeting Autoimmunity
Researchers have developed a strategy to treat a rare autoimmune disease which could lead to treatments of other autoimmune diseases.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
Protein Nanocages Could Improve Drug Design and Delivery
HHMI scientists have designed and built 10 large protein icosahedra that are similar to viral capsids that carry viral DNA.
Development in Preventing Macular Degeneration
Following macular degeneration insight, promising drugs to prevent vision loss have been identified.
Improving Tumour Therapy with Nanoparticles
UHN nanoparticle called PEARLs is a promising utilisation of photo-thermal therapy for cancer treatment.
New Antidepressant Treatment Discovered
Scientists have demonstrated how gene therapy could lead to new treatments for depression.
Cellular Origin of Skin Cancer Identified
Scientists have identified ‘cell of origin’ in the most common form of skin cancer, and followed the process that leads to tumour growth.
Enhancing Drug Safety with a Web-Based Data Tool
Online and open-access tool allows anyone to find, combine and analyse FDA drug information.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!