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Thermo Fisher Scientific Offers HRAM Library for Environmental, Food Safety, Clinical Research, Toxicology

Published: Thursday, June 19, 2014
Last Updated: Thursday, June 19, 2014
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30,000 MS/MS spectra for 2,000 compounds boost confidence in results, method flexibility

Laboratories analyzing environmental, clinical research/toxicological, and food samples have a powerful new data tool expected to save time and money while identifying compounds with high levels of confidence. 

Thermo Fisher Scientific has announced its high resolution accurate mass (HRAM) spectral library.

“This is a true library with full, high-resolution spectra for every compound it contains,” said Jennifer Massi, program manager, environmental and food safety for Thermo Fisher Scientific. “In fact, we ran multiple MS/MS spectra for each compound, and each was analyzed at multiple collision energies. This is designed to enhance method flexibility and confidence in results.”

The library was generated using the Thermo Scientific Q Exactive liquid chromatography-mass spectrometry (LC-MS) system at 140,000 resolution to minimize false positives and negatives as well as matrix interference. Spectra are searchable using Thermo Scientific TraceFinder software. The library contains compounds for environmental and food safety analysis that include: pesticides, mycotoxins, veterinary drugs, perfluorinated chemicals (PFCs) and other environmental contaminants. For clinical/toxicological research, it contains spectra for therapeutic and prescription drugs, illegal drugs and toxins.

The library is designed to help customers save time in method development by using defined retention times, and by searching the five most intense ions. Customers can save money because the library reduces the need to purchase standards to set up new libraries.  Method development flexibility is enhanced because spectra are generated at multiple collision energies per compound.


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