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Scientific News
Computer Simulations Reveal the Energy Landscape of Ion Channels
A team of researchers have investigated the opening and closing mechanisms of these channels: for the first time the full energy landscape of such a large protein could be calculated.
Schmidt Fund Awards to Advance Innovations in Drug Therapy and Search for Planets
Two Princeton University research projects have been selected to receive grants from Princeton's Eric and Wendy Schmidt Transformative Technology Fund.
Side Effects to be Discovered more Quickly, Leading to Safer Prescribing
BMJ Learning has teamed up with the MHRA to launch a new, interactive and multimedia learning module on pharmacovigilance.
Researchers Discover New Therapy for Fragile X Chromosome Syndrome
Researchers at the University of the Basque Country (UPV/EHU) and the Achucarro neurosciences centre have discovered a new therapy for the fragile X chromosome syndrome.
Onconova Announces Positive Data of Oral Rigosertib in Advanced Head and Neck Cancer
Oral rigosertib progresses to phase 2 clinical trial in squamous cell head and neck cancers.
Startup Launched from Georgia Tech-Emory University Research Receives $7.9 Million
Clearside Biomedical, Inc. has received $7.9 million in funding to continue drug and technology development for treatment of ocular diseases.
Unanticipated Consequences of DNA Hypomethylation; Loss and Gain of Polycomb Mediated Transcription Repression in Somatic Cells
By genome-wide mapping of the Polycomb Repressive Complex 2 (PRC2)-signature histone mark, H3K27me3, in DNA methylation-deficient mouse somatic cells, the Meehan lab shows that loss of DNA methylation is coincident with widespread H3K27me3 redistribution.
Yale Researchers Trick Bacteria to Deliver a Safer Vaccine
Yale researchers have developed a new trick, using bacteria’s own cellular mistakes to deliver a safe vaccine.
Trackable Drug-Filled Nanoparticles - a Potential Weapon against Cancer
Tiny particles filled with a drug could be a new tool for treating cancer in the future.
Amphetamine Positive Urine Toxicology Screen Secondary to Atomoxetine
We present a case of a young female patient taking atomoxetine irregularly whose urine drug screen returned as a false-positive amphetamine result that was not confirmed.

miRNA Replacement Therapy in Cancer through Polyplex-Mediated miRNA Delivery In Vivo
Professor Achim Aigner, Institute of Pharmacology / bpc, Philipps-University Marburg, speaking at RNAi Europe 2011.

Biotests for Hazard Characterization of Waste
Dr Reinhilde Weltens, Vito, speaking at Advances in Biosensors and Biodetection.

Drug Discovery Outsourcing: the Importance of Integration in the Selection of Higher Quality Clinical Candidates
Simone Braggio, Director, Head of Drug Metabolism & Pharmacokinetics, Aptuit speaking at Pharma Outsourcing Congress 2011

Approach to Quick Lead Optimization Including Physicochemical and ADME Profiling
Pranas Japertas, Director, ACD Labs, Speaking at Medchem Europe 2011.

Preclinical Drug Safety: High Quality Data obtained with a New Automated Patch Clamp Platform
Olaf Scheel, CSO, Cytocentrics AG speaking at Pharma Outsourcing Congress 2011

In a Virtual World, Where Are the Walls of the House?  The New Outsourcing
Katya Tsaioun, President, Apredica speaking at Pharma Outsourcing Congress 2011

Voltage-Gated Sodium Channel Activators with Differing Efficacies Stimulate Neurite Outgrowth in Cerebrocortical Neurons
Thomas Murray, Professor and Chair, Creighton University School of Medicine, speaking at Screening Europe 2010

Pharmacogenomics of Drug Disposition: From Polymorphisms to Biomarkers
Urs A. Meyer, Emeritus Professor, Biozentrum, University of Basel speaking at ADMET Europe 2011

Clinical Trials Utilising Radioactivity in Support of Drug Development
Stephen Madden, Head, Metabolism and Pharmacokinetics, Charles River speaking at ADMET Europe 2011

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