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The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Vitamin A May Help Improve Pancreatic Cancer Chemotherapy
The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London (QMUL).
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Non-Toxic Approach to Treating Variety of Cancers
A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.
Making Injectable Medicine Safer
Researchers remove excess additives from drugs, which could reduce the odds of serious allergic reactions and other side effects.
An Old-New Weapon Against Emerging Chikungunya Virus
Researchers utilize existing drugs to interfere with host factors required for replication of Chikungunya virus.
Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models
First direct experimental proof of causal effect, researchers say.
'Kidney on a Chip' Facilitates Safer Drug Dosing
University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.
Ketamine Metabolism Lifts Depression
NIH-funded team finds rapid-acting, non-addicting agent in mouse study.

3D Organotypic Liver Cultures and their Application in Predictive Toxicology
Fozia Noor, Saarland University, speaking at Advances in cellular Assays & Cell Culture 2014

Combining Computational Biology and High Content Imaging Approaches for Understanding DNA Damage and Repair
Thierry Dorval, AstraZeneca, speaking at High Content Analysis 2014

Tumour Regression after Intravenous Administration of Novel Tumour-targeted Nanomedicines
Christine Dufes, University of Strathclyde, speaking at Nanomedicine 2014.

Nanomedicines to Improve the Therapeutic Index of Drugs in Modern Drug Design
Marianne Ashford, AstraZeneca, speaking at Nanomedicine 2014.

Using In vitro and In vivo Models to Assess the Local and Systemic Responses to Nanomaterial Exposure
Vicki Stone, Heriot-Watt University, speaking at Nanomedicine 2014.

Improved Oral Delivery of Antiretroviral Drugs Via A Novel Synthesis of Solid Drug Nanoparticle Formulations
Andrew Owen, University of Liverpool, speaking at Nanomedicine 2014.

Biodegradable and Biocompatible Comb-Like Polymers for Biomedical Applications
Davide Moscatelli, Politecnico di Milano, speaking at Nanomedicine 2014.

Biotransformation: Still a Bottleneck for in Vitro Kinetic and Dynamic Approaches
Sandra Coecke, European Centre for the Validation of Alternative Methods, speaking at ADME & Predictive Toxicology Europe

Technology Spotlight: microRNA Biomarkers in Biofluids: Challenges and Solutions
Ditte Andreasen, Exiqon, speaking at Genomics Research Europe 2013.

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