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Scientific News
ADME of Antibody-Maytansinoid Conjugates
Continued understanding of the ADME properties of ADCs entering clinical evaluations should provide additional insight into attributes that may be necessary for clinical success.
Epigenetic Regulation of ADME-Related Genes
The promise of epigenetic research is its potential to identify additional sources of inter individual variability in drug disposition and response.
NIST Instrument Enables High-speed Chemical Imaging of Tissues
Researchers have demonstrated a dramatically improved technique for analyzing biological cells and tissues based on characteristic molecular vibration "signatures."
Finding Could Revolutionize Drug Discovery
A study by researchers at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Researchers Develop ‘Onion’ Vesicles for Drug Delivery
University of Pennsylvania researchers have shown that dendrimer-based vesicles self-assemble with concentric layers of membranes, much like an onion.
Validation of Drug Toxicity Prediction using DiscoveRx Model
BioMAP® Systems was shown to identify important safety aspects of drugs and chemicals more efficiently and accurately than can be achieved by animal testing.
System 'Prints' Precise, Tailored Drug Dosages
The new approach uses a combination of data and mathematics to determine the precise dosage.
Mice and Rats Stressed by Male Experimenters
An international team of pain researchers led by scientists at McGill University have found that the gender of the experimenters has a big impact on the stress levels of rodents.
Skin Layer Grown in Lab Could Replace Animal Testing
Skin layer grown from human stem cells could replace animals in drug and cosmetics testing.
Observing Behavior of Single Molecules in Real Time
New technique developed by Stanford scientists allows observation of single molecules of protein or DNA as they bind with other molecules.

Cationic Nanoparticles for Cancer Chemotherapy
Erem Bilensoy, Associate Professor, Hacettepe University Faculty of Pharmacy, speaking at Nanomedicine Europe 2013.

Improved Uptake of Drugs for Cancer Treatment by Cyclodextrin Carriers
Gerhard Wenz, University of Saarland, speaking at Discovery Chemistry Congress 2013.

Enhancing Drug Solubility through Phrase Separation/Coacervation and Spray Drying
Kamal Jonnalagadda, University of the Sciences in Philadelphia, speaking at Discovery Chemistry Congress 2013.

An Integrated System Using Peptide Arrays to Assess Kinase and Nuclear Receptor Activities in Clinical Samples for Biomarker Development
Bertrand Jordan, Aix-Marseille University, speaking at Microarray World Congress 2012

Phenotypic Drug Screening: the Power of High Capacity Flow
Dr Kim Luu, Intellicyt, Inc., speaking at European Laboratory Automation 2012.

Identifying miRNA in Biofluids to be Applied as Robust Biomarkers for Disease, Toxicology or Injury Studies – The case of Minimally Invasive Colorectal Cancer Detection
Peter Mouritzen, Exiqon, speaking at Genomics Research Europe 2012

Multi-analyte Procedures for Target Screening and Quantification of Drugs in Blood using LC-MS/MS: Possibilities and Limitations
Hans Maurer, Saarland University, speaking at European Lab Automation 2012.

Dynamic Cell Culture for Drug Discovery: Stretching Mechanotransduction from the Lung to the Lab
Dr. Sanjit Nirmalanandhan, University of Kansas Medical Center, speaking at Cell Culture 2012.

Microfabricated Cell-Culture Platforms to Study Cell Function and Drug Response in Engineered 2D and 3D Microenvironments
Marcus Textor, ETH Zurich, speaking at Single Cell Analysis Europe 2012.

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