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The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Vitamin A May Help Improve Pancreatic Cancer Chemotherapy
The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London (QMUL).
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Non-Toxic Approach to Treating Variety of Cancers
A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.
Making Injectable Medicine Safer
Researchers remove excess additives from drugs, which could reduce the odds of serious allergic reactions and other side effects.
An Old-New Weapon Against Emerging Chikungunya Virus
Researchers utilize existing drugs to interfere with host factors required for replication of Chikungunya virus.
Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models
First direct experimental proof of causal effect, researchers say.
'Kidney on a Chip' Facilitates Safer Drug Dosing
University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.
Ketamine Metabolism Lifts Depression
NIH-funded team finds rapid-acting, non-addicting agent in mouse study.

Improved Uptake of Drugs for Cancer Treatment by Cyclodextrin Carriers
Gerhard Wenz, University of Saarland, speaking at Discovery Chemistry Congress 2013.

Enhancing Drug Solubility through Phrase Separation/Coacervation and Spray Drying
Kamal Jonnalagadda, University of the Sciences in Philadelphia, speaking at Discovery Chemistry Congress 2013.

An Integrated System Using Peptide Arrays to Assess Kinase and Nuclear Receptor Activities in Clinical Samples for Biomarker Development
Bertrand Jordan, Aix-Marseille University, speaking at Microarray World Congress 2012

Phenotypic Drug Screening: the Power of High Capacity Flow
Dr Kim Luu, Intellicyt, Inc., speaking at European Laboratory Automation 2012.

Identifying miRNA in Biofluids to be Applied as Robust Biomarkers for Disease, Toxicology or Injury Studies – The case of Minimally Invasive Colorectal Cancer Detection
Peter Mouritzen, Exiqon, speaking at Genomics Research Europe 2012

Multi-analyte Procedures for Target Screening and Quantification of Drugs in Blood using LC-MS/MS: Possibilities and Limitations
Hans Maurer, Saarland University, speaking at European Lab Automation 2012.

Dynamic Cell Culture for Drug Discovery: Stretching Mechanotransduction from the Lung to the Lab
Dr. Sanjit Nirmalanandhan, University of Kansas Medical Center, speaking at Cell Culture 2012.

Microfabricated Cell-Culture Platforms to Study Cell Function and Drug Response in Engineered 2D and 3D Microenvironments
Marcus Textor, ETH Zurich, speaking at Single Cell Analysis Europe 2012.

Regulation of Cytochrome P450s and Nuclear Receptor by microRNAs and its Toxicological Implications
Tsuyoshi Yokoi, Kanazawa University, speaking at ADME & Predictive Toxicology Europe

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