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Scientific News
UW-Madison Team Developing ‘Tissue Chip’ to Screen Neurological Toxins
A faster, more affordable way to screen for neural toxins.
Promise for Treatment of Pancreatic Cancer
Ultrasound microbubbles can improve tumor absorption of cancer drugs.
Animal Testing can Mislead Drug Discovery and Development
Several blockbuster drugs would not be on the market, if scientists had relied solely on drug-uptake in animal trials, according to new research.
Marijuana Compound May Offer Treatment for AD
Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease.
New Advances in the Pre-clinical Evaluation of Hepatitis B Therapies
Imperial College London to present first public HBV Data from CN Bio in vitro liver model.
ADME of Antibody-Maytansinoid Conjugates
Continued understanding of the ADME properties of ADCs entering clinical evaluations should provide additional insight into attributes that may be necessary for clinical success.
Epigenetic Regulation of ADME-Related Genes
The promise of epigenetic research is its potential to identify additional sources of inter individual variability in drug disposition and response.
NIST Instrument Enables High-speed Chemical Imaging of Tissues
Researchers have demonstrated a dramatically improved technique for analyzing biological cells and tissues based on characteristic molecular vibration "signatures."
Finding Could Revolutionize Drug Discovery
A study by researchers at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Researchers Develop ‘Onion’ Vesicles for Drug Delivery
University of Pennsylvania researchers have shown that dendrimer-based vesicles self-assemble with concentric layers of membranes, much like an onion.

When is a Genotoxin not a Genotoxin?
Richard Walmsley, University of Manchester, speaking at ADME & Predictive Toxicology Europe

miRNA Replacement Therapy in Cancer through Polyplex-Mediated miRNA Delivery In Vivo
Professor Achim Aigner, Institute of Pharmacology / bpc, Philipps-University Marburg, speaking at RNAi Europe 2011.

Biotests for Hazard Characterization of Waste
Dr Reinhilde Weltens, Vito, speaking at Advances in Biosensors and Biodetection.

Drug Discovery Outsourcing: the Importance of Integration in the Selection of Higher Quality Clinical Candidates
Simone Braggio, Director, Head of Drug Metabolism & Pharmacokinetics, Aptuit speaking at Pharma Outsourcing Congress 2011

Approach to Quick Lead Optimization Including Physicochemical and ADME Profiling
Pranas Japertas, Director, ACD Labs, Speaking at Medchem Europe 2011.

Preclinical Drug Safety: High Quality Data obtained with a New Automated Patch Clamp Platform
Olaf Scheel, CSO, Cytocentrics AG speaking at Pharma Outsourcing Congress 2011

In a Virtual World, Where Are the Walls of the House?  The New Outsourcing
Katya Tsaioun, President, Apredica speaking at Pharma Outsourcing Congress 2011

Voltage-Gated Sodium Channel Activators with Differing Efficacies Stimulate Neurite Outgrowth in Cerebrocortical Neurons
Thomas Murray, Professor and Chair, Creighton University School of Medicine, speaking at Screening Europe 2010

Pharmacogenomics of Drug Disposition: From Polymorphisms to Biomarkers
Urs A. Meyer, Emeritus Professor, Biozentrum, University of Basel speaking at ADMET Europe 2011

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