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The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Non-Toxic Approach to Treating Variety of Cancers
A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.
Making Injectable Medicine Safer
Researchers remove excess additives from drugs, which could reduce the odds of serious allergic reactions and other side effects.
An Old-New Weapon Against Emerging Chikungunya Virus
Researchers utilize existing drugs to interfere with host factors required for replication of Chikungunya virus.
Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models
First direct experimental proof of causal effect, researchers say.
'Kidney on a Chip' Facilitates Safer Drug Dosing
University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.
Ketamine Metabolism Lifts Depression
NIH-funded team finds rapid-acting, non-addicting agent in mouse study.
Turning Skin Cells into Heart, Brain Cells
In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.
Growing Stem Cells More Safely
Nurturing stem cells atop a bed of mouse cells works well, but is a non-starter for transplants to patients – Brown University scientists are developing a synthetic bed instead.

Contactless Impedance Analysis for Real-Time Cell Monitoring
Tim Cox, Research Director, Institute of Bio-sensing Technology, speaking at Advances in Biodetection and Biosensors 2012.

US Patent Law of 2011 the Good the Bad and the Expensive
Thomas Saunders, Rissman Hendricks & Oliverio, speaking at Drug Chemistry Congress 2012.

Defence and Adaptation in Drug-Mediated Liver Toxicity
Christopher Goldring, University of Liverpool, speaking at ADME & Predictive Toxicology Europe 2012

Rationalizing ADME in the Current Regulatory and Business Environment
Robert Guttendorf, Aclairo Pharmaceutical Development Group, speaking at ADME & Predictive Toxicology Europe

Metabolites and Safety, the MIST and ICH-M3 GUIDANCE and their Impact on ADME
Gerhard Gross, Lundbeck Pharma, speaking at ADME & Predictive Toxicology Europe 2012

Emerging Outsourcing Destinations Pharmas Strategies and Growth Drivers
Dr Jim J. Zhang, JZMed, Inc., speaking at Discovery Chemistry Congress 2012.

In Vitro, Ex Vivo and in Models to Develop New Therapies for Renal Diseases
Frederick W. K. Tam, Imperial College London, speaking at ADME & Predictive Toxicology Europe 2012

Biotransformation: Still a Bottleneck for in Vitro Kinetic and Dynamic Approaches
Sandra Coecke, European Centre for the Validation of Alternative Methods, speaking at ADME & Predictive Toxicology Europe

In Silico Toxicology: Where are We at and Where are We Going?
John C. Dearden, Liverpool John Moores University, speaking at ADME & Predictive Toxicology Europe 2012

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