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Scientific News
Observing Behavior of Single Molecules in Real Time
New technique developed by Stanford scientists allows observation of single molecules of protein or DNA as they bind with other molecules.
Development and Validation of LC/MS/MS Method and its Application to a Pharmacokinetic Study
Researchers aimed to develop a LC/MS/MS method to monitor plasma levels of montelukast, gliclazide, and nifedipine for application in pharmacokinetic studies and routine clinical practice.
Mini-Livers Show Promise to Reduce Animal Use in Science
Using this method, cells from one mouse could be used to test 1000 drug compounds to treat liver disease, and reduce animal use by up to 50,000.
Advancing the Knowledge of Pharmaceutical Processes
Linkam Scientific Instruments report on the use of their stages in the study of pharmaceutical processes.
Gathering and Exploring Scientific Knowledge in Pharmacovigilance
The holistic assessment of widespread electronic medical records empowers valuable insights over adverse drug events.
A Silk Coat for Diamonds Makes Sleek New Imaging and Drug Delivery Tool
New kind of tiny glowing particle could provide a novel technique for biological imaging and drug delivery.
Biases in Animal Studies may Differ from those in Clinical Trials
New analysis of animal studies on cholesterol-lowering statins found that non-industry studies had results that favored the drugs even more than studies funded by industry.
TAP Biosystems Presents New Data on 3D Cell Culture Research
Discussing the application of RAFT 3D models in oncology, toxicology and neuroscience cell-based screening programmes.
Scripps' Scientists Develop Promising Drug Candidates for Pain and Addiction
Two new drug scaffolds offer researchers novel tools that act on the kappa opioid receptor.
World’s Tiniest Drug Cabinets could be Attached to Cancerous Cells for Long Term Treatment
Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments.

A Project Driven Approach to Efficient Generation of QSAR Models
Adrian Stevens, Lead Scientist, Accelrys, speaking at ADMET Europe

In Silico Methods for ADMET and Solubility Prediction
John Mitchell, Group Leader, University of St-Andrews, speaking at ADMET Europe

Metabonomics – Recent Advances in Multivariate Methods and some Results Relating to Diabetes
Richard Barton, Professor, Imperial College London, speaking at ADMET Europe

Drug-Drug Interactions Involving non-CYP Phase I or Phase II Enzymes can we Predict?
Olivier Barberan, Director of Product Development, Aureus Pharma, speaking at ADMET Europe

Illuminating Your Pathway to Discovery: Cell based Assays For Efficacy and Safety Profiling
Martin Augustin, European Technology Manager, Drug Discovery, Millipore, speaking at Screening Europe 2010

MS Binding Assays - A New Concept for Drug Screening
Klaus Wanner, Full Professor, Ludwig- Maximilians-University Munich, speaking at Screening Europe 2009

Pharmacological Characterization of GPRC6A – A 7TM Receptor Activated by L-a-Amino Acids and Positively Modulated by Divalent Cations
Petrine Wellendorph, Associate Professor, University of Copenhagen, speaking at Screening Europe 2009

Testing Drug-Induced Inhibition of hERG: How Voltage and Inactivation Makes a Difference
Harry Witchel, Senior Lecturer in Physiology, Brighton and Sussex Medical School, University of Sussex, speaking at ADMET Europe 2009

Development of Proteomics Methods for Profiling Cytochrome P450s
Chris Sutton, Head of the ICT Proteomics and Mass Spectrometry Facility, Bradford University, speaking at ADMET Europe 2009

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