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Scientific News
An Unlikely Use for Diamonds
Tiny diamonds provide new possibilities for accurate measurements of processes inside living cells with potential to improve drug delivery and cancer therapeutics.
Microscopic “Walkers” Find Their Way Across Cell Surfaces
Technology could provide a way to deliver probes or drugs to cell structures without outside guidance.
Revalesio’s Drug Shows Promise in Treating Alzheimer’s
Multiple published research studies outline the potential for RNS60 to effectively treat Alzheimer’s disease by protecting neuronal function and restoring neuronal plasticity.
Getting Metabolism Right
Analysis of 89 models of metabolic processes finds flaws in 44 of them — but suggests corrections.
Persistent Pharmacokinetic Challenges to Pediatric Drug Development
Current knowledge of rational drug dose adjustments is limited, greater effort needs to be made to determine ontogenic factors that influence ADME.
‘Tissue Chip’ to Screen Neurological Toxins
UW-Madison team are developing a faster, more affordable way to screen for neural toxins.
Promise for Treatment of Pancreatic Cancer
Ultrasound microbubbles can improve tumor absorption of cancer drugs.
Animal Testing can Mislead Drug Discovery and Development
Several blockbuster drugs would not be on the market, if scientists had relied solely on drug-uptake in animal trials, according to new research.
Marijuana Compound May Offer Treatment for AD
Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease.
New Advances in the Pre-clinical Evaluation of Hepatitis B Therapies
Imperial College London to present first public HBV Data from CN Bio in vitro liver model.

Use of Informatics Approaches in Risk Assessments
Sandeep Modi, Cheminformatician, Unilever speaking at ADMET Europe 2011

Drug Metabolism and Toxicity: Influence of Genetic and Epigenetic Factors
Magnus Ingelman-Sundberg, Professor and Head of Pharmacogenetics, Karolinska Institutet speaking at ADMET Europe 2011

Physiologically Based Pharmacokinetic/Pharmacodynamic Modelling for Lead Optimisation of CNS-Active Therapeutics
Simon Thomas, Cyprotex, speaking at Screening Europe 2010

Predicting Hepatotoxicity with CellCiphr HCS technology: Rat and Human Hepatotoxicity Predicton: Validation and Case Studies
Katya Tsaioun, CSO, Cyprotex speaking at ADMET Europe 2011

Metabolomics Platform for Toxicology Research in Zebrafish
Elwin Verheij, TNO, speaking at European Biomarkers Summit 2010.

A Novel Strategy for Bespoke Tissue-Specific Biomarkers for Drug Development
Gary Coulton, Director, University of London, speaking at European Biomarkers Summit 2010.

Dried Blood Spot Samples for ADME, Biomarker Analysis and Metabolomics
Elwin Verheij, Innovation Manager, TNO, speaking at ADMET Europe

Predicting the Kinetics of Drugs in the Brain
Simon Thomas, Head of Scientific Computing, Cyprotex Discovery Ltd, speaking at ADMET Europe

A Project Driven Approach to Efficient Generation of QSAR Models
Adrian Stevens, Lead Scientist, Accelrys, speaking at ADMET Europe

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