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Scientific News
A Toxicokinetic Model for Thiamethoxam in Rats: Implications for Higher-Tier Risk Assessment
Toxicokinetic models are promising for wildlife risk assessments, but good understanding of feeding patterns is needed for accurate estimation of chronic risk.
IBN Creates Unlimited Source of Human Kidney Cells
Applications include in vitro toxicology, disease models & regenerative medicine.
Researchers Identify Novel Class of Drugs for Prostate Cancers
A new study on prostate cancer describes a novel class of drugs that interrupts critical signaling needed for prostate cancer cells to grow.
Molecular Modelling to Help Create Better, Safer Drugs
How our bodies break down the common drugs ibuprofen, diclofenac and warfarin is the subject of a new study from the University of Bristol.
Computer Simulations Reveal the Energy Landscape of Ion Channels
A team of researchers have investigated the opening and closing mechanisms of these channels: for the first time the full energy landscape of such a large protein could be calculated.
Schmidt Fund Awards to Advance Innovations in Drug Therapy and Search for Planets
Two Princeton University research projects have been selected to receive grants from Princeton's Eric and Wendy Schmidt Transformative Technology Fund.
Side Effects to be Discovered more Quickly, Leading to Safer Prescribing
BMJ Learning has teamed up with the MHRA to launch a new, interactive and multimedia learning module on pharmacovigilance.
Researchers Discover New Therapy for Fragile X Chromosome Syndrome
Researchers at the University of the Basque Country (UPV/EHU) and the Achucarro neurosciences centre have discovered a new therapy for the fragile X chromosome syndrome.
Onconova Announces Positive Data of Oral Rigosertib in Advanced Head and Neck Cancer
Oral rigosertib progresses to phase 2 clinical trial in squamous cell head and neck cancers.
Startup Launched from Georgia Tech-Emory University Research Receives $7.9 Million
Clearside Biomedical, Inc. has received $7.9 million in funding to continue drug and technology development for treatment of ocular diseases.

Novel Recombinant Peptide Toxin Fusion Proteins as Potential Therapeutics for the Treatment of Autoimmune Disease
Hung Nguyen, Principal Scientist, Amgen, speaking at Ion Channel Targets 2008

Chemogenomics in Drug Discovery
Hugo Kubinyi, Retired Professor, Pharmaceutical Chemistry, University of Heidelberg, speaking at MedChem Europe 2009

Prediction of Drug-Drug Interactions Caused by Metabolism-Based Inhibition of Cytochrome P450 Using a Mechanistic Static Model: The Weak & Missing Links?
Olivier Barberan, Director of Product Development, AUREUS-Pharma, speaking at ADMET Europe 2009

Ion Channel Panels for Safety Assessment and Drug Discovery
Arthur "Buzz" Brown, President & CEO, ChanTest Corporation, speaking at Ion Channel Targets 2008

Chemical Activation of Voltage-Gated Potassium Channels
Min Li, Professor, Department of Neuroscience & High Throughput Biology Center, Johns Hopkins School of Medicine, speaking at Ion Channel Targets 2008

Keynote Address – The Many Roles of Cyberinfastructure in Virtual Discovery
Katherine Kantardjieff, Professor, University of California - Fullerton, speaking at Virtual Discovery 2008

In silico ADMET Traffic Lights and PhysChem Scores and Their Application to Kinase Inhibitors
Mario Lobell, Computational Chemist, Bayer HealthCare, speaking at Virtual Discovery, 2007

Virtual Screening in Lead Discovery
Hugo Kubinyi, Professor of Pharmaceutical Chemistry, University of Heidelberg, speaking at Virtual discovery 2007

The Way to Safety Biomarkers: Holy Grail of Toxicology
Thomas Herget, Director New Technology Evaluation, Division Chemicals R&D, Merck, speaking at the European Biomarkers Summit, 2007

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