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The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Non-Toxic Approach to Treating Variety of Cancers
A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.
Making Injectable Medicine Safer
Researchers remove excess additives from drugs, which could reduce the odds of serious allergic reactions and other side effects.
An Old-New Weapon Against Emerging Chikungunya Virus
Researchers utilize existing drugs to interfere with host factors required for replication of Chikungunya virus.
Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models
First direct experimental proof of causal effect, researchers say.
'Kidney on a Chip' Facilitates Safer Drug Dosing
University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.
Ketamine Metabolism Lifts Depression
NIH-funded team finds rapid-acting, non-addicting agent in mouse study.
Turning Skin Cells into Heart, Brain Cells
In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.
Growing Stem Cells More Safely
Nurturing stem cells atop a bed of mouse cells works well, but is a non-starter for transplants to patients – Brown University scientists are developing a synthetic bed instead.

Pharmacogenomics of Drug Disposition: From Polymorphisms to Biomarkers
Urs A. Meyer, Emeritus Professor, Biozentrum, University of Basel speaking at ADMET Europe 2011

Clinical Trials Utilising Radioactivity in Support of Drug Development
Stephen Madden, Head, Metabolism and Pharmacokinetics, Charles River speaking at ADMET Europe 2011

Use of Informatics Approaches in Risk Assessments
Sandeep Modi, Cheminformatician, Unilever speaking at ADMET Europe 2011

Drug Metabolism and Toxicity: Influence of Genetic and Epigenetic Factors
Magnus Ingelman-Sundberg, Professor and Head of Pharmacogenetics, Karolinska Institutet speaking at ADMET Europe 2011

Physiologically Based Pharmacokinetic/Pharmacodynamic Modelling for Lead Optimisation of CNS-Active Therapeutics
Simon Thomas, Cyprotex, speaking at Screening Europe 2010

Predicting Hepatotoxicity with CellCiphr HCS technology: Rat and Human Hepatotoxicity Predicton: Validation and Case Studies
Katya Tsaioun, CSO, Cyprotex speaking at ADMET Europe 2011

Metabolomics Platform for Toxicology Research in Zebrafish
Elwin Verheij, TNO, speaking at European Biomarkers Summit 2010.

A Novel Strategy for Bespoke Tissue-Specific Biomarkers for Drug Development
Gary Coulton, Director, University of London, speaking at European Biomarkers Summit 2010.

Dried Blood Spot Samples for ADME, Biomarker Analysis and Metabolomics
Elwin Verheij, Innovation Manager, TNO, speaking at ADMET Europe

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