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Scientific News
Observing Behavior of Single Molecules in Real Time
New technique developed by Stanford scientists allows observation of single molecules of protein or DNA as they bind with other molecules.
Development and Validation of LC/MS/MS Method and its Application to a Pharmacokinetic Study
Researchers aimed to develop a LC/MS/MS method to monitor plasma levels of montelukast, gliclazide, and nifedipine for application in pharmacokinetic studies and routine clinical practice.
Mini-Livers Show Promise to Reduce Animal Use in Science
Using this method, cells from one mouse could be used to test 1000 drug compounds to treat liver disease, and reduce animal use by up to 50,000.
Advancing the Knowledge of Pharmaceutical Processes
Linkam Scientific Instruments report on the use of their stages in the study of pharmaceutical processes.
Gathering and Exploring Scientific Knowledge in Pharmacovigilance
The holistic assessment of widespread electronic medical records empowers valuable insights over adverse drug events.
A Silk Coat for Diamonds Makes Sleek New Imaging and Drug Delivery Tool
New kind of tiny glowing particle could provide a novel technique for biological imaging and drug delivery.
Biases in Animal Studies may Differ from those in Clinical Trials
New analysis of animal studies on cholesterol-lowering statins found that non-industry studies had results that favored the drugs even more than studies funded by industry.
TAP Biosystems Presents New Data on 3D Cell Culture Research
Discussing the application of RAFT 3D models in oncology, toxicology and neuroscience cell-based screening programmes.
Scripps' Scientists Develop Promising Drug Candidates for Pain and Addiction
Two new drug scaffolds offer researchers novel tools that act on the kappa opioid receptor.
World’s Tiniest Drug Cabinets could be Attached to Cancerous Cells for Long Term Treatment
Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments.

Chemogenomics in Drug Discovery
Hugo Kubinyi, Retired Professor, Pharmaceutical Chemistry, University of Heidelberg, speaking at MedChem Europe 2009

Prediction of Drug-Drug Interactions Caused by Metabolism-Based Inhibition of Cytochrome P450 Using a Mechanistic Static Model: The Weak & Missing Links?
Olivier Barberan, Director of Product Development, AUREUS-Pharma, speaking at ADMET Europe 2009

Ion Channel Panels for Safety Assessment and Drug Discovery
Arthur "Buzz" Brown, President & CEO, ChanTest Corporation, speaking at Ion Channel Targets 2008

Chemical Activation of Voltage-Gated Potassium Channels
Min Li, Professor, Department of Neuroscience & High Throughput Biology Center, Johns Hopkins School of Medicine, speaking at Ion Channel Targets 2008

Keynote Address – The Many Roles of Cyberinfastructure in Virtual Discovery
Katherine Kantardjieff, Professor, University of California - Fullerton, speaking at Virtual Discovery 2008

In silico ADMET Traffic Lights and PhysChem Scores and Their Application to Kinase Inhibitors
Mario Lobell, Computational Chemist, Bayer HealthCare, speaking at Virtual Discovery, 2007

Virtual Screening in Lead Discovery
Hugo Kubinyi, Professor of Pharmaceutical Chemistry, University of Heidelberg, speaking at Virtual discovery 2007

The Way to Safety Biomarkers: Holy Grail of Toxicology
Thomas Herget, Director New Technology Evaluation, Division Chemicals R&D, Merck, speaking at the European Biomarkers Summit, 2007

Quintessential Electrophysiology: ICRAC Recordings on the Q-Patch
Dr. Dayne Okuhara, Synta Pharmaceuticals speaking at Ion Channel Targets 2006.

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