Keeping Tumor Growth at Bay Engineers at Washington University in St. Louis found a way to keep a cancerous tumor from growing by using nanoparticles of the main ingredient in common antacid tablets.Cancer Cells Kill Off Healthy Neighbours Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.Future of Medicine Could be Found in a Tiny Crystal Ball A Drexel University materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate medication in a way that would allow it to deliver its curative payload more effectively inside the body.Bile Acid Supports Production of Blood Stem Cells A research group at Lund University has been able to show that bile acid is transferred from the mother to the foetus via the placenta to enable the foetus to produce blood stem cells.Chemical Used to Replace BPA is Potentially Toxic This study is the first to examine the effects of BPA and BPS on brain cells and genes that control the growth and function of organs involved in reproduction.A Better Model for Parkinson's Scientists at EPFL solve a longstanding problem with modeling Parkinson’s disease in animals. Using newfound insights, they improve both cell and animal models for the disease, which can propel research and drug development.Improving Delivery of Poorly Soluble Drugs Using Nanoparticles A technology that could forever change the delivery of drugs is undergoing evaluation by the Technology Evaluation Consortium™ (TEC). Developed by researchers at Northeastern University, the technology is capable of creating nanoparticle structures that could deliver drugs into the bloodstream orally – despite the fact that they are normally poorly soluble.Toxicity Testing With Cultured Liver Cells Microreactor replaces animal testing. Neural Networks Adapt to the Presence of a Toxic HIV Protein HIV-associated neurocognitive disorders (HAND) afflict approximately half of HIV infected patients.Faster Drug Discovery? Startup develops more cost-effective test for assessing how cells respond to chemicals.
Physiologically Based Pharmacokinetic/Pharmacodynamic Modelling for Lead Optimisation of CNS-Active Therapeutics Simon Thomas, Cyprotex, speaking at Screening Europe 2010
Predicting Hepatotoxicity with CellCiphr HCS technology: Rat and Human Hepatotoxicity Predicton: Validation and Case Studies Katya Tsaioun, CSO, Cyprotex speaking at ADMET Europe 2011
Metabolomics Platform for Toxicology Research in Zebrafish Elwin Verheij, TNO, speaking at European Biomarkers Summit 2010.
A Novel Strategy for Bespoke Tissue-Specific Biomarkers for Drug Development Gary Coulton, Director, University of London, speaking at European Biomarkers Summit 2010.
Dried Blood Spot Samples for ADME, Biomarker Analysis and Metabolomics Elwin Verheij, Innovation Manager, TNO, speaking at ADMET Europe
Predicting the Kinetics of Drugs in the Brain Simon Thomas, Head of Scientific Computing, Cyprotex Discovery Ltd, speaking at ADMET Europe
A Project Driven Approach to Efficient Generation of QSAR Models Adrian Stevens, Lead Scientist, Accelrys, speaking at ADMET Europe
In Silico Methods for ADMET and Solubility Prediction John Mitchell, Group Leader, University of St-Andrews, speaking at ADMET Europe
Metabonomics – Recent Advances in Multivariate Methods and some Results Relating to Diabetes Richard Barton, Professor, Imperial College London, speaking at ADMET Europe