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Scientific News
Novel Organoid Matrix Enables Long-Term Culture of Human Hepatocytes
Organoid growth matrix to enable long-term culture of genome-stable bipotent stem cells from adult human liver.
First Contracting Human Muscle Grown in Laboratory
Researchers at Duke University report the first lab-grown, contracting human muscle, which could revolutionize drug discovery and personalized medicine.
Antriabio Announces Completion Of PK/PD Studies Of AB101
AB101 positioned to be the first once-weekly basal insulin for diabetes patients.
Anti-Diabetic Drug Springs New Hope for Tuberculosis Patients
Drug for treating diabetes can double up as adjunct treatment for tuberculosis.
A Poisonous Cure
Toxic fungi may hold the secrets to tackling deadly diseases.
Antibiotic Resistance Threatens Future of Modern Medicine
Overuse and misuse of antibiotics, one of the key contributors to antimicrobial resistance (AMR).
Bacterial Toxin Targets Discovered
Understanding how bacterial toxins target human cells is set to have major implications for the development of novel drugs.
Proteomics for Systems Toxicology
MS-based proteomics is maturing into a robust technology for the measurement of proteome-wide exposure effects.
Molecular Event Mapping Opens Door to more in silico Tests
It is hoped that this new approach to mapping and predicting the impact of chemical compounds in the body could reduce the need for toxicity tests in animals.
Protein-engineered Cages Aid Studies of Cell Functions
The Cages, from researchers at Tokyo Institute of Technology, to deliver an important signalling molecule, carbon monoxide, into cells.

Hypertension in P2Y2 Receptor-Deficient Mice is Caused by Constitutive Activation of ENaC
James Stockand, Associate Professor, University of Texas Health Science Center at Houston, speaking at Ion Channel Targets 2008

Mechanosensitivity, A Wide Open Field
Frederick Sachs, Distinguished Professor, New York State University at Buffalo, speaking at Ion Channel Targets 2008

Novel Recombinant Peptide Toxin Fusion Proteins as Potential Therapeutics for the Treatment of Autoimmune Disease
Hung Nguyen, Principal Scientist, Amgen, speaking at Ion Channel Targets 2008

Chemogenomics in Drug Discovery
Hugo Kubinyi, Retired Professor, Pharmaceutical Chemistry, University of Heidelberg, speaking at MedChem Europe 2009

Prediction of Drug-Drug Interactions Caused by Metabolism-Based Inhibition of Cytochrome P450 Using a Mechanistic Static Model: The Weak & Missing Links?
Olivier Barberan, Director of Product Development, AUREUS-Pharma, speaking at ADMET Europe 2009

Ion Channel Panels for Safety Assessment and Drug Discovery
Arthur "Buzz" Brown, President & CEO, ChanTest Corporation, speaking at Ion Channel Targets 2008

Chemical Activation of Voltage-Gated Potassium Channels
Min Li, Professor, Department of Neuroscience & High Throughput Biology Center, Johns Hopkins School of Medicine, speaking at Ion Channel Targets 2008

Keynote Address – The Many Roles of Cyberinfastructure in Virtual Discovery
Katherine Kantardjieff, Professor, University of California - Fullerton, speaking at Virtual Discovery 2008

In silico ADMET Traffic Lights and PhysChem Scores and Their Application to Kinase Inhibitors
Mario Lobell, Computational Chemist, Bayer HealthCare, speaking at Virtual Discovery, 2007

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