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Retractable Protein Nanoneedles
The ability to control the transfer of molecules through cellular membranes is an important function in synthetic biology; a new study from researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) introduces a novel mechanical method for controlling release of molecules inside cells.
Iron in the Blood Could Cause Cell Damage
Concentrations of iron similar to those delivered through standard treatments can trigger DNA damage within 10 minutes, when given to cells in the laboratory.
Advancing Synthetic Biology
Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules — the enzymes.
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Honey’s Potential to Save Lives
The healing powers of honey have been known for thousands of years.
Muscles on-a-Chip
This study may help explain why stem cell-based therapies have so far shown limited benefits for heart attack patients in clinical trials.
3-D Printed Lifelike Liver Tissue for Drug Screening
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling.
Envigo Rat Models Proven to be Susceptible to Intra-Vaginal HSV-2 Infection and Protectable
Scientific findings establish the effectiveness of new approach to investigate the protective effects of vaccine candidates and anti-viral microbodies and to study asymptomatic primary genital HSV-2 infection.
Valvena, GSK Sign New R&D Collaboration
Valneva to supply process development services for EB66® -based Influenza vaccines.
Food Triggers Creation of Regulatory T Cells
IBS researchers document how normal diet establishes immune tolerance conditions in the small intestine.

Drug-Drug Interactions Involving non-CYP Phase I or Phase II Enzymes can we Predict?
Olivier Barberan, Director of Product Development, Aureus Pharma, speaking at ADMET Europe

Illuminating Your Pathway to Discovery: Cell based Assays For Efficacy and Safety Profiling
Martin Augustin, European Technology Manager, Drug Discovery, Millipore, speaking at Screening Europe 2010

MS Binding Assays - A New Concept for Drug Screening
Klaus Wanner, Full Professor, Ludwig- Maximilians-University Munich, speaking at Screening Europe 2009

Pharmacological Characterization of GPRC6A – A 7TM Receptor Activated by L-a-Amino Acids and Positively Modulated by Divalent Cations
Petrine Wellendorph, Associate Professor, University of Copenhagen, speaking at Screening Europe 2009

Testing Drug-Induced Inhibition of hERG: How Voltage and Inactivation Makes a Difference
Harry Witchel, Senior Lecturer in Physiology, Brighton and Sussex Medical School, University of Sussex, speaking at ADMET Europe 2009

Development of Proteomics Methods for Profiling Cytochrome P450s
Chris Sutton, Head of the ICT Proteomics and Mass Spectrometry Facility, Bradford University, speaking at ADMET Europe 2009

Kinase Inhibitors with Tailored Binding Kinetics by Fragment-Based Design
Peter Sennhenn, Head of Medicinal Chemistry, Proteros fragments GmbH, speaking at MedChem Europe 2009

Impedance-Based Measurement of GPCR Modulators in Drug Discovery – Characterization of Signalling Pathways in Recombinant and Non-Recombinant Cells
John Gatfield, Senior Lab Head Molecular Biology, Actelion Pharmaceuticals Ltd, speaking at Screening Europe 2009

Advancing Drug Discovery in an Academic Setting
Julie Frearson, Professor Biotechnology/Drug Discovery/Biological Chemistry and Molecular Pharmacology, University of Dundee, speaking at Screening Europe 2009

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