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AccuPrep GMO DNA Extraction Kit
AccuPrep GMO DNA Extraction Kit
2010 Geno/Grinder®
2010 Geno/Grinder®

Webcasts
Capturing D Genome Variation for Wheat ImprovementCapturing D Genome Variation for Wheat Improvement
Eric Olson, Michigan State University, speaking at Advances in Plant Genomics 2014
Characterising Plant Genomes The Good The Bad and The UglyCharacterising Plant Genomes The Good The Bad and The Ugly
Dave Edwards, University of Queensland, speaking at Advances in Plant Genomics 2014

Market Reports
Algae Biofuel: Why Not Now?
Select Biosciences Ltd

Algae biofuel is either just around the corner or off in the distant future. Which? We used a patented technology mapping process from Emerging Tech Insights, Inc. to answer the question and to Get Beyond the Hype® in algae biofuels.
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Global Pipeline of New GM Crops
European Unioins JRC

A new publication provides a detailed list of products in the commercial, regulatory and advanced R&D pipelines.
Scientific News
Tick Genome Reveals Secrets of a Successful Bloodsucker
NIH has announced that decipher the genome of the blacklegged tick which could lead to new tick control methods.
Custom Tuning Knobs to Turn Off Any Gene
Factory managers can improve productivity by telling workers to speed up, slow down or stop doing tangential tasks while assembling widgets. Unfortunately for synthetic biologists attempting to produce pharmaceuticals, microbes don’t respond to direction like human personnel.
Tick Genome Reveals Secrets of a Successful Bloodsucker
NIH-funded study could lead to new tick control methods.
New Method Promises to Speed Development of Food Crops
A new study addresses a central challenge of transgenic plant development: how to reliably evaluate whether genetic material has been successfully introduced.
Where Cancer Cells May Begin
Scientists use fruit fly genetics to understand how things could go wrong in cancer.
Key Enzyme in Pierce’s Disease Grapevine Damage Uncovered
UC Davis plant scientists have identified an enzyme that appears to play a key role in the insect-transmitted bacterial infection of grapevines with Pierce’s disease, which annually costs California’s grape and wine industries more than $100 million.
Bacteria Attack Lignin with Enzymatic Tag Team
Team from Rice, University of Wisconsin-Madison shows how nature handles lignin.
Milestone Resource in Wheat Research Now Available for Download
Leading on from The Genome Analysis Centre’s (TGAC) previous announcement of their new bread wheat genome assembly, the landmark resource is now publically available to download at the European Bioinformatics Institute’s (EMBL-EBI) Ensembl database for full analysis.
Nano-Reactor for the Production of Hydrogen Biofuel
Combining bacterial genes and virus shell creates a highly efficient, renewable material used in generating power from water.
Cleaning Wastewater with Pond Scum
A blob of algae scooped from a fountain on South Street almost two years ago, has seeded a crop of the green stuff that Drexel University researchers claim is more effective at treating wastewater than many of the processes employed in municipal facilities today.
Business News
Pints and PhDs
On Tuesday 26 January, three scientists from The Genome Analysis Centre (TGAC) helped kick-off the first installment of ‘PubhD’ at the Cellar House in Eaton, Norwich.
Twist Bioscience Raises $61M
Oversubscribed round validates twist bioscience’s acceleration of research and development through synthetic DNA.
Canadian Government Invests in Species ID Research
Canadian Minister of Health Jane Philpott announced at the University of Guelph today a new federal investment in genomics research to improve plant protection and food safety regulation.
BioAscent, Pierre Fabre Collaborate
Pharma and cosmetics multinational selects BioAscent as central hub for storage and logistics of extensive plant natural extracts collection.
Bio-Genesys, Affymetrix Partner
Partnership to offer animal genomic testing services to professional farming operations.
Era7 Receives $430K Grant
Era7 is granted with $430 K to develop a bioinformatics platform integrated with the Electronic Health Record for human microbiome analysis.
Douglas Scientific, TATAA Biocenter Collaborate
Both Companies launch new high throughput PCR services.
Field labs give insights into blackgrass control and compost teas
As the warm wet weather encourages winter-sown wheat to get away, concerns are being raised that blackgrass is also thriving.
TGAC Appoints New Director
The Genome Analysis Centre (TGAC) is delighted to announce the appointment of Professor Neil Hall as its new Director.
PBL Signs License Agreement with Thermo Fisher
Agreement for Baulcombe & Hamilton RNAi patent.

Events
4th Biotechnology World Congre
15 Feb 2016
4th Biotechnology World Congre ...
Pittcon 2016
06 Mar 2016
Pittcon 2016 ...
Plant Improvement Technologies
30 Mar 2016
Plant Improvement Technologies ...
Plant Genomics Asia
11 Apr 2016
Plant Genomics Asia ...

ePosters
Design considerations for highly specific and efficient synthetic crRNA molecules
GE Healthcare Dharmacon, Inc.

An overview of our rational design algorithm for picking highly functional crRNA sequences in combination with comprehensive specificity analysis.
Picking the best CRISPR-Cas9 targets for functional gene knockout: a machine learning algorithm based on both specificity and functionality
GE Healthcare Dharmacon, Inc.

The CRISPR-Cas9 system has the potential to significantly advance basic and applied research.
Scaffold design, function and over-expression of lentiviral-based microRNAs
GE Healthcare Dharmacon, Inc.

Here we describe the strategy for scaffold design, the importance of an optimal promoter, and demonstrate gene target down-regulation from the over-expression of lentiviral microRNA mimics.
Homology-directed repair with Dharmacon™ Edit-R™ CRISPR-Cas9 and single-stranded DNA oligos
GE Healthcare Dharmacon, Inc.

Here we demonstrate how to perform lipid based transfections for homology directed repair using DharmaFECT Duo, CRISPR-Cas9 reagents and, synthetic DNA donor oligos.
Tools for studying and using small RNAs: from pathways to functions to therapies
Cold Spring Harbor Laboratory, Watson School of Biological Sciences

This poster provides an overview of the tools that have been developed to understand the functions of small RNAs and, conversely, the use of small RNAs as tools. Tools that are based on small RNAs have been exploited to investigate gene function in cultured cells and in living animals. Small RNA biogenesis, discovery and functional roles are explored in detail. Screening approaches to functional genomics, in vivo methods and potential therapeutic applications are discussed.
Increasing gene editing efficiencies in eukaryotic cell lines by selection of appropriate CRISPR-Cas9 reagents
GE Healthcare Dharmacon, Inc.

Overview of various CRISPR-Cas9 reagents to provide the highest efficiency of gene editing in your experiments.
Knockdown of p53 by Accell self-delivering siRNA causes inhibition of p53-dependent DNA damage response in IMR-32 neuroblastoma cell line and β-amyloid toxicity in rat cortical neurons
GE Healthcare Dharmacon, Inc.

Here we describe how application of Accell siRNA enabled the development of a high content screening assay in IMR-32 neuroblastoma cells and a whole culture cell viability assay in primary rat cortical neurons.
High Performance Comprehensive Two-Dimensional Gas Chromatography Coupled with a High Resolution Multi-Reflecting TOFMS for Confident Non-Target Analyte Identification
LECO Corporation, Restek Corporation

The use of comprehensive two-dimensional gas chromatography to help increase chromatographic resolution is a major step in tackling the problem of confident peak identification in a complex sample matrix. Combining the separation power of two-dimensional gas chromatography, with resolving power greater than 25,000, and sub ppm mass accuracies of a high resolution multi-reflecting TOFMS is the ideal solution to confident compound identification within a complex sample matrix.
An Efficient Method for the Incorporation of Molecular Probes at Multiple/Specific sites in RNA: Levulinyl Protection for 2'-ACE ® , 5'-Silyl Oligoribonucleotide Synthesis
GE Healthcare Dharmacon, Inc.

A unique method that uses a levulinate ester as a protecting group to introduce conjugates or molecular probes to virtually any location in a synthetic RNA molecule is discussed. The Levulinyl protecting group is stable in RNA synthesis conditions and can be removed without affecting the other parts of the synthesized RNA. We show the capabilities of this approach with three high-complexity synthesis examples.
Bovine RNA-seq data analysis of liver and pituitary gland
(1) Functional Genomics Lab. Faculty of Biology and Environmental Protection, Nicolaus Copernicus University, Torun, Poland, (2) Interdisciplinary Centre of Modern Technology, Nicolaus Copernicus Uni

Two key applications of RNA-seq i.e., i) transcriptome read mapping to a reference genome and ii) SNP detections were investigated to analysis of bovine liver and pituitary gland transcriptome. Here, we have presented ONLY the obtained results of bovine pituitary gland.
Application Notes
Muliplex SNP Genotyping of Field Corn Crude Samples with Probe-Based Assays using the IntelliQube® from Douglas Scientific®
Douglas Scientific

This study evaluated multiplex genotyping on the IntelliQube, a PCR instrument optimized for 1.6 µL reaction volumes in Array Tape®. It demonstrates the feasibility of achieving two SNP genotyping results in a single reaction well. IntelliQube provides cost savings through miniaturized PCR reaction volumes, shorter thermal cycling times, and multiplex reactions without compromising data quality.
Double stranded DNA quantitation using Promega QuantiFluor® Dyes
Tecan Group Ltd.

Achieving selective and sensitive quantitation of double stranded DNA (dsDNA) using spectrophotometric methods can be problematic. Recognizing these difficulties, researchers have incorporated fluorescence-based quantitation techniques in their workflows to obtain the required sensitivity and target selectivity.
Gas Chromatographic Analysis of Polyunsaturated FAME in Biodiesel Made From Algae and Marine Oils
Agilent Technologies

This application note describes the configuration and performance of the Agilent 7890A GC system when using this method for the analysis of B100 biodiesel derived from algae oil.
Automating Complex Sample Preparations Using the Agilent 7696A WorkBench
Agilent Technologies

The 7696A Workbench is a standalone instrument specifically designed to automate sample preparation.
Analysis of Natural Oils and Extracts Using the Low Thermal Mass LTM Series II System
Agilent Technologies

The enantiomers of linalool and other important components of natural oils or natural extracts including cypress oil, geranium extract, balm leaves oil, and jasmin oil are separated on a multidimensional system using two separate GC ovens.
Analysis of Organophosphorus Pesticides with Agilent 7820 Gas Chromatograph Flame Photometric Detector


The Agilent 7820 series gas chromatograph (GC) equipped with a flame photometric detector (FPD) provides high sensitivity, good linearity, and stability for the analysis of organophosphorus pesticides.
Analysis of Glycerin and Glycerides in Biodiesel (B100) Using ASTM D6584 and EN14105
Agilent Technologies

This application provides complete system configuration as well as guidelines for successful analysis of free glycerin and total glycerides in biodiesel.
Monitoring Bacterial Cell-to-Cell Communication “Quorum sensing” Using FLUOstar OPTIMA
BMG Labtech

Bacteria can monitor and respond to changes to environmental conditions via a cell density process known as quorum sensing. Bacteria use this process to monitor their community by producing, detecting and responding to low molecular mass signal molecules, called autoinducers. Effects on quorum sensing were investigated by measuring growth and bioluminescence of Vibrio fischeri. The FLUOstar OPTIMA was utilized to measure absorbance and luminescence in parallel.
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