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Characterizing the Performance of qPCR I...
 An Illustrated History of Gas Chromatog...Fast PCR with AllinOneCycler & AccuPower...CappBravo Single Channel Pipette...

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2010 Geno/Grinder®
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Troubleshooting Liquid Handler Methods Troubleshooting Liquid Handler Methods
Join us for this webinar which will provide participants with the knowledge necessary to get the most out of any liquid handling platform.
The Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in DiseaseThe Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in Disease
Join us to learn about the key challenges in lipid analysis and how the Lipidyzer platform can help you overcome them.

Market Reports
Algae Biofuel: Why Not Now?
Select Biosciences Ltd

Algae biofuel is either just around the corner or off in the distant future. Which? We used a patented technology mapping process from Emerging Tech Insights, Inc. to answer the question and to Get Beyond the Hype® in algae biofuels.
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Global Pipeline of New GM Crops
European Unioins JRC

A new publication provides a detailed list of products in the commercial, regulatory and advanced R&D pipelines.
Scientific News
Featured Article
How it Works: Advanced Data Analysis Using Visualization
Visualisation of data can be used to help molecular biologists tackle the vast datasets their experiments create.

Observing Direct Inheritance of Gene-Silencing RNA
Research has allowed for the observation of double-stranded RNA molecule being passed from parent to offspring in roundworms.
Driving Mosquito Evolution to Fight Malaria
Researchers propose insect repellent in conjunction with insecticides to extend current insecticide lifetime.
Genes Help Track Odd Migrations of Zika Mosquitoes
Study shows that mosquitoes carrying Zika virus or Dengue fever a genetically distinct around the world.
Wrapping up the Genome
Researchers successfully package complete yeast genome using purified components, yielding new insights into genome mechanisms.
Enlisting Insects to Protect Agriculture
New program aims for insect delivery of protective genes to modify mature plants within a single growing season.
New Mechanism of Plant RNA Degradation Identified
Researchers have identified a novel mechanism by which RNA is degraded.
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
New Model for Understanding Human Myeloma
Researchers develop mouse model where mice carry six human genes involved in human tumour growth.
3D-Printing in Science: Conference Co-Staged with LABVOLUTION
LABVOLUTION 2017 will have an added highlight of a simultaneous conference, "3D-Printing in Science".
Business News
Innovation For An Agricultural Revolution
How can technology from other industries help transform agriculture? That's one of the big questions to be discussed by technologists, agronomists and producers at the annual Agri-Tech East conference, REAP, on 9th November at the Wellcome Genome Campus Conference Centre.
smartLAB 2017: For Tomorrow’s Intelligent Laboratories
smartLAB 2017 will be held 16-18 May at LABVOLUTION along side BIOTECHNICA life sciences show.
Monsanto, Dow AgroSciences Collaborate on EXZACT Technology
The EXZACT™ Precision Technology® Platform for research and commercial development of new crop solutions across Monsanto Company’s research portfolio.
Gen9 Announces Winners of Fourth Annual G-Prize
1 million base pairs of DNA awarded to support leading-edge projects in plant cell signaling and vitamin cell factory development.
DuPont, CIMMYT Partner
Partnership aims to develop improved crops using CRISPR-Cas advanced plant breeding technology for characteristics that address the needs of smallholder farmers around the world.
DuPont Pioneer, CIMMYT Form CRISPR Partnership
Agreement designed to improve livelihoods of smallholder maize and wheat farmers globally.
Monsanto, Broad Institute Announce Global Licensing Agreement
The license to CRISPR-Cas from the Broad Institute provides access to an exciting tool for our growing body of genome-editing research.
Bayer to Acquire Monsanto for $66B
Acquisition realises a shared vision of integrated agricultural offerings, delivering enhanced solutions for growers and creates a leading innovation engine for the next generation of farming.
Monsanto, Second Genome Collaborate
Collaboration aims to use microbiome technology platform to accelerate protein discovery.
£9M Funding to Optimise UK Food Supply
Five research prjects have been awarded a portion of £9M to help increase resilience in UK food systems.

Pittcon 2017
05 Mar 2017
Pittcon 2017 ...
5th Plant Genomics & Gene Edit
16 Mar 2017
5th Plant Genomics & Gene Edit ...
Arablab 2017
20 Mar 2017
Arablab 2017 ...
qPCR, dPCR & NGS 2017
03 Apr 2017
qPCR, dPCR & NGS 2017 ...

The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry
GE Healthcare Dharmacon, Inc.

Dharmacon has previously developed a novel RNA synthesis chemistry making RNA synthesis as reliable, accessible and of comparable quality as routinely observed in DNA synthesis.
Blood Transcriptomic Diagnosis of Active TB with Five Genes
1Infection & Immunity, University College London, UK 2Department of Microbiology, University College London Hospitals NHS Trust, UK 3Blizard Institute, Queen Mary Univ

This study aimed to identify the minimal set of genes that can accurately diagnose active TB, both pulmonary and extrapulmonary, and evaluate their specificity.
Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA
Dharmacon, part of GE Healthcare

Precise genome engineering with CRISPR-Cas9 and single-stranded DNA oligo or double-stranded DNA plasmid donors via homology-directed repair (HDR).
Super-resolution single molecule localization microscopy of the exocytotic machinery underlying insulin secretion.
Heriot-Watt Univeristy

Single molecule imaging of the tSNARE proteins involved in insulin secretion.
A Synthetic CRISPR-Cas9 System for Homology-directed Repair
Dharmacon (part of GE Healthcare)

Synthetic, dual-RNA-encoded Cas9 is used for precise homology-directed repair (HDR) gene engineering. Both short and long (GFP) inserts are covered.
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
Dharmacon (part of GE Healthcare)

CRISPR-Cas9 gene editing using synthetic crRNA:tracrRNA or sgRNA is highly efficient and easy to use. Synthetic crRNA:tracrRNA is uniquely suited to in vitro and in vivo applications, in particular, DNA-free approach with Cas9 mRNA. Chemical synthesis of guide RNAs allows accurate and rapid production of arrayed crRNA libraries for high-confidence, loss-of-function screens.
The Case for CASE: Computer-Assisted Structure Elucidation

Modern CASE systems such as Structure Elucidator Suite provide the necessary capability to accurately elucidate a novel chemical structure for complex molecules based on readily available NMR data sets. This allows organizations to avoid expensive, labor-intensive, and time-consuming synthetic efforts.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Customizable exon-centric target enrichment strategy for copy number and SNP analysis
Agilent Technologies

Agilent’s Custom OneSeq provides a comprehensive, flexible, and cost-effective means to identify exon-level copy number changes as well as SNP/INDEL in one assay.
Rapid electrochemical impedance spectroscopy for protein detection in Lab-on-a-Chip devices
(a) Thomas Johann Seebeck Department of Electronics, Tallinn University of Technology, Tallinn, Estonia; (b) Protobios OÜ, Tallinn, Estonia

We present results in rapid solution impedance spectroscopy to detect protein interactions (antibody-antigen) in human serum. Two different serum-antibody mixtures are measured in cuvettes, interfaced with screen-printed electrodes to determine whether the experimental setup can detect differences in composition.
Application Notes
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research

The Lipidyzer™ Platform, powered by Metabolon®.
Novel Chemical Standards Kits Enable Facile Lipid Quantitation

The Lipidyzer platform provides more accurate lipid analysis with less quantitative bias.
SNP Genotyping of Field Corn Samples with LGC Genomics Chemistry on the Nexar® System
Douglas Scientific

A recent study demonstrated that the Nexar® System can be successfully used to produce repeatable and easily scored SNP genotyping results with crude preps from field corn using either KASP or probe-based SNP genotyping assays in miniaturized reaction volumes. This platform also provides significant cost savings in the form of reduced PCR reaction volumes.
Rapid point of use DNAble® assay for citrus greening disease (Candidatus Liberibacter spp.) using the Douglas Scientific® AmpliFire®
Douglas Scientific

In this experiment, a crude insect preparation and a DNAble assay were used to demonstrate that the AmpliFire instrument accurately detects the presence of HLB-causing bacteria consistent with a real-time PCR system. The AmpliFire offers greater portability than real-time PCR instrumentation, and is a powerful tool for point of use applications such as management of citrus greening disease.
Characterization of the FlexJet® with Multi-Array Dispense for Reduction of Chemistry Waste Due to Overage
Douglas Scientific

This study demonstrates that the Nexar® with the FlexJet multi-array dispense feature can reduce master mix consumed as dead volume by 87.5% compared to Dispense Jet single-array dispense. The capability to perform multi-array dispense with one aspiration also produces repeatable and accurate results and is an ideal solution for genotyping applications.
Muliplex SNP Genotyping of Field Corn Crude Samples with Probe-Based Assays using the IntelliQube® from Douglas Scientific®
Douglas Scientific

This study evaluated multiplex genotyping on the IntelliQube, a PCR instrument optimized for 1.6 µL reaction volumes in Array Tape®. It demonstrates the feasibility of achieving two SNP genotyping results in a single reaction well. IntelliQube provides cost savings through miniaturized PCR reaction volumes, shorter thermal cycling times, and multiplex reactions without compromising data quality.
Double stranded DNA quantitation using Promega QuantiFluor® Dyes
Tecan Group Ltd.

Achieving selective and sensitive quantitation of double stranded DNA (dsDNA) using spectrophotometric methods can be problematic. Recognizing these difficulties, researchers have incorporated fluorescence-based quantitation techniques in their workflows to obtain the required sensitivity and target selectivity.
Gas Chromatographic Analysis of Polyunsaturated FAME in Biodiesel Made From Algae and Marine Oils
Agilent Technologies

This application note describes the configuration and performance of the Agilent 7890A GC system when using this method for the analysis of B100 biodiesel derived from algae oil.
Automating Complex Sample Preparations Using the Agilent 7696A WorkBench
Agilent Technologies

The 7696A Workbench is a standalone instrument specifically designed to automate sample preparation.
Analysis of Natural Oils and Extracts Using the Low Thermal Mass LTM Series II System
Agilent Technologies

The enantiomers of linalool and other important components of natural oils or natural extracts including cypress oil, geranium extract, balm leaves oil, and jasmin oil are separated on a multidimensional system using two separate GC ovens.

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