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Characterizing the Performance of qPCR I...
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Webcasts
Troubleshooting Liquid Handler Methods Troubleshooting Liquid Handler Methods
Join us for this webinar which will provide participants with the knowledge necessary to get the most out of any liquid handling platform.
Preventing Contamination in Cell Culture LabsPreventing Contamination in Cell Culture Labs
Join us to learn how to apply aseptic techniques and preventative hygiene for preventing contamination by incorporating standard procedures into your daily culture practice.

Market Reports
Algae Biofuel: Why Not Now?
Select Biosciences Ltd

Algae biofuel is either just around the corner or off in the distant future. Which? We used a patented technology mapping process from Emerging Tech Insights, Inc. to answer the question and to Get Beyond the Hype® in algae biofuels.
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Global Pipeline of New GM Crops
European Unioins JRC

A new publication provides a detailed list of products in the commercial, regulatory and advanced R&D pipelines.
Scientific News
Gene Could Reduce Female Mosquitoes
Virginia Tech researchers have found a gene that can reduce female mosquitoes over many generations.
Improving Crop Efficiency with CRISPR
New study of CRISPR-Cas9 technology from Virginia Tech shows potential to improve crop efficiency.
Fighting Plant Pathogens with RNA
Researchers develop strategy that could lead to environmentally friendly fungicide to fight pathogens.
Breakthrough in Plant Salt-Tolerance Research
Researchers have made a breakthrough in plant salt tolerance that could lead to new salt tollerant crop types.
Microbes Help Plants Survive In Severe Drought
Researchers discover plants survive better under drought conditions with help from natural microbes.
Mosquito Genetics Determine Tastes
Study reveals mosuito's preference for human versus animal biting is determined by genetics.
Mouse Genes Guiding Precision Medicine
Research of the mouse genome has identified hundreds of essential-to-life genes from the 1751 genes studied.
Environmental Impact of GM Crops
Following the adoption of GM crops, insecticide usage decreases but herbicide use increases, study shows.
Genes Essential to Life Discovered
Genes critical for life are discovered in humans and mice as part of large-scale phenotyping study.
Protein That Initiates DNA Repair Found
Researchers have identified a protein that may initiate a cascade of molecular activity to repair DNA damage.
Business News
Monsanto, Broad Institute Announce Global Licensing Agreement
The license to CRISPR-Cas from the Broad Institute provides access to an exciting tool for our growing body of genome-editing research.
Bayer to Acquire Monsanto for $66B
Acquisition realises a shared vision of integrated agricultural offerings, delivering enhanced solutions for growers and creates a leading innovation engine for the next generation of farming.
Monsanto, Second Genome Collaborate
Collaboration aims to use microbiome technology platform to accelerate protein discovery.
£9M Funding to Optimise UK Food Supply
Five research prjects have been awarded a portion of £9M to help increase resilience in UK food systems.
£4.5M Newton Fund to Tackle Antimicrobial Resistance
Six research partnerships tackling the rise of anti-microbial resistance (AMR) have been created with £4.5M investment by the UK Research Councils.
Robots Emerging as Agricultural Co-Workers
Advanced engineering could be the solution for the sustainable intensification of agriculture, as technology for producing service robots reaches maturity.
UK-Brazil Wheat Research Projects Awarded £4M
£4M investment from BBSRC and Embrapa has been awarded to four Brazil-UK partnerships.
Monsanto, Nomad Bioscience Announce Collaboration
Monsanto and Nomad Bioscience have announced a licensing agreement whereby Monsanto has obtained rights to apply Nomad’s proprietary technology to its genome-editing projects aimed at enhancement of agricultural crops.
Robotics and Plant Intelligence Win GROW Agri-tech Competition
Agri-Tech East cluster supports pipeline of innovation with the UK's only national agri-tech business plan competition.
Benson Hill, Danforth Plant Science Center Announce Partnership
Partnership aims to create sustainable sources of bioenergy.

Events
Troubleshooting Liquid Handlin
27 Sep 2016
Troubleshooting Liquid Handlin ...
Preventing contamination in ce
28 Sep 2016
Preventing contamination in ce ...
Synthetic Biology
20 Oct 2016
Synthetic Biology ...
4th European Food Safety and S
24 Oct 2016
4th European Food Safety and S ...

ePosters
Blood Transcriptomic Diagnosis of Active TB with Five Genes
1Infection & Immunity, University College London, UK 2Department of Microbiology, University College London Hospitals NHS Trust, UK 3Blizard Institute, Queen Mary Univ

This study aimed to identify the minimal set of genes that can accurately diagnose active TB, both pulmonary and extrapulmonary, and evaluate their specificity.
Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA
Dharmacon, part of GE Healthcare

Precise genome engineering with CRISPR-Cas9 and single-stranded DNA oligo or double-stranded DNA plasmid donors via homology-directed repair (HDR).
Super-resolution single molecule localization microscopy of the exocytotic machinery underlying insulin secretion.
Heriot-Watt Univeristy

Single molecule imaging of the tSNARE proteins involved in insulin secretion.
A Synthetic CRISPR-Cas9 System for Homology-directed Repair
Dharmacon (part of GE Healthcare)

Synthetic, dual-RNA-encoded Cas9 is used for precise homology-directed repair (HDR) gene engineering. Both short and long (GFP) inserts are covered.
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
Dharmacon (part of GE Healthcare)

CRISPR-Cas9 gene editing using synthetic crRNA:tracrRNA or sgRNA is highly efficient and easy to use. Synthetic crRNA:tracrRNA is uniquely suited to in vitro and in vivo applications, in particular, DNA-free approach with Cas9 mRNA. Chemical synthesis of guide RNAs allows accurate and rapid production of arrayed crRNA libraries for high-confidence, loss-of-function screens.
The Case for CASE: Computer-Assisted Structure Elucidation
ACD/Labs

Modern CASE systems such as Structure Elucidator Suite provide the necessary capability to accurately elucidate a novel chemical structure for complex molecules based on readily available NMR data sets. This allows organizations to avoid expensive, labor-intensive, and time-consuming synthetic efforts.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Rapid electrochemical impedance spectroscopy for protein detection in Lab-on-a-Chip devices
(a) Thomas Johann Seebeck Department of Electronics, Tallinn University of Technology, Tallinn, Estonia; (b) Protobios OÜ, Tallinn, Estonia

We present results in rapid solution impedance spectroscopy to detect protein interactions (antibody-antigen) in human serum. Two different serum-antibody mixtures are measured in cuvettes, interfaced with screen-printed electrodes to determine whether the experimental setup can detect differences in composition.
Advanced Microfluidic Mixing Device for the Study of Macromolecule Dynamics
Department of Biomedical, IIT Hyderabad

We have developed and characterized a micro-fluidic mixer to study the macro-molecule dynamics such as kinetics of protein folding, DNA sequencing, single molecule study and detection etc. on a micro-second timescale. Numerical simulation has been performed to analyse the study of mixing performance of micro-fluidics channel.
DNA-free CRISPR-Cas9 genome engineering in zebrafish
Dharmacon (part of GE Healthcare)

Poster describing the advantages of a DNA-free gene editing system and the application of this system in zebrafish.
Application Notes
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research
SCIEX

The Lipidyzer™ Platform, powered by Metabolon®.
Novel Chemical Standards Kits Enable Facile Lipid Quantitation
SCIEX

The Lipidyzer platform provides more accurate lipid analysis with less quantitative bias.
SNP Genotyping of Field Corn Samples with LGC Genomics Chemistry on the Nexar® System
Douglas Scientific

A recent study demonstrated that the Nexar® System can be successfully used to produce repeatable and easily scored SNP genotyping results with crude preps from field corn using either KASP or probe-based SNP genotyping assays in miniaturized reaction volumes. This platform also provides significant cost savings in the form of reduced PCR reaction volumes.
Rapid point of use DNAble® assay for citrus greening disease (Candidatus Liberibacter spp.) using the Douglas Scientific® AmpliFire®
Douglas Scientific

In this experiment, a crude insect preparation and a DNAble assay were used to demonstrate that the AmpliFire instrument accurately detects the presence of HLB-causing bacteria consistent with a real-time PCR system. The AmpliFire offers greater portability than real-time PCR instrumentation, and is a powerful tool for point of use applications such as management of citrus greening disease.
Characterization of the FlexJet® with Multi-Array Dispense for Reduction of Chemistry Waste Due to Overage
Douglas Scientific

This study demonstrates that the Nexar® with the FlexJet multi-array dispense feature can reduce master mix consumed as dead volume by 87.5% compared to Dispense Jet single-array dispense. The capability to perform multi-array dispense with one aspiration also produces repeatable and accurate results and is an ideal solution for genotyping applications.
Muliplex SNP Genotyping of Field Corn Crude Samples with Probe-Based Assays using the IntelliQube® from Douglas Scientific®
Douglas Scientific

This study evaluated multiplex genotyping on the IntelliQube, a PCR instrument optimized for 1.6 µL reaction volumes in Array Tape®. It demonstrates the feasibility of achieving two SNP genotyping results in a single reaction well. IntelliQube provides cost savings through miniaturized PCR reaction volumes, shorter thermal cycling times, and multiplex reactions without compromising data quality.
Double stranded DNA quantitation using Promega QuantiFluor® Dyes
Tecan Group Ltd.

Achieving selective and sensitive quantitation of double stranded DNA (dsDNA) using spectrophotometric methods can be problematic. Recognizing these difficulties, researchers have incorporated fluorescence-based quantitation techniques in their workflows to obtain the required sensitivity and target selectivity.
Gas Chromatographic Analysis of Polyunsaturated FAME in Biodiesel Made From Algae and Marine Oils
Agilent Technologies

This application note describes the configuration and performance of the Agilent 7890A GC system when using this method for the analysis of B100 biodiesel derived from algae oil.
Automating Complex Sample Preparations Using the Agilent 7696A WorkBench
Agilent Technologies

The 7696A Workbench is a standalone instrument specifically designed to automate sample preparation.
Analysis of Natural Oils and Extracts Using the Low Thermal Mass LTM Series II System
Agilent Technologies

The enantiomers of linalool and other important components of natural oils or natural extracts including cypress oil, geranium extract, balm leaves oil, and jasmin oil are separated on a multidimensional system using two separate GC ovens.
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