Corporate Banner
Satellite Banner
AgriGenomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

£1.1 Million Boost for Synthetic Biology Research in Bristol

Published: Monday, November 12, 2012
Last Updated: Monday, November 12, 2012
Bookmark and Share
University of Bristol scientists have been awarded a £1.1 million share of the Biotechnology and Biological Sciences Research Council (BBSRC)'s strategic Longer and Larger Awards in Synthetic Biology.

The award for an ambitious programme of research into natural biological 'factories' and their role in producing novel agrochemicals is worth a total of £4.5 million, shared between the Universities of Bristol, Cambridge, Manchester and Warwick.

Microorganisms produce many compounds, notably penicillin made by a fungus, which are beneficial to human health and agriculture.  Most microbes have the genetic capacity to produce very many more compounds than are actually observed in nature.  If their full potential could be activated, a strong flow of new compounds for use as medicines and agrochemicals would result.

The BBSRC-funded research will exploit these natural product assembly lines to discover and optimise novel agrochemicals.  The scientists will rapidly sequence the genomes of 40 microorganisms with the known ability to produce compounds beneficial to agriculture.  The clusters of genes responsible for the production of these compounds will be identified and manipulated to make new and hopefully useful products.

The project is a partnership between the four universities, with additional scientific and financial input from Syngenta.  Bristol’s expertise is focused in the School of Chemistry where Professor Russell Cox and Professor Tom Simpson FRS will lead a multidisciplinary team, including the groups of Dr Matt Crump and Professor Christine Willis, investigating how fungi make compounds with potential for use in agriculture.

The Chemistry team have built their internationally recognised success on collaboration with Dr Andy Bailey and Dr Colin Lazarus in the School of Biological Sciences and Dr Paul Race in the School of Biochemistry.

The latest award builds on previous BBSRC-funded research between the Bristol team and Syngenta using synthetic biology approaches to develop new herbicides from fungi.  Together the Bristol team have raised £3.2 million from research councils and industry over the past 3 years for innovative research into the biosynthesis of natural products from fungi and bacteria. The new BBSRC sLOLA funding brings this total to £4.3 million.

Professor Russell Cox said: “This is great news for the University of Bristol and for UK industry.  Synthetic biology offers real hopes for the rapid development of new products which will underpin agriculture and food security.  We plan to use our expertise in fungal chemistry to develop new products and more sustainable routes to them.”


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Genome of 700,000-Year-Old Horse Sequenced
The oldest genome so far from a prehistoric creature has been sequenced by an international team.
Thursday, June 27, 2013
Scientific News
Marijuana Genome Unraveled
A study by Canadian researchers is providing a clearer picture of the evolutionary history and genetic organization of cannabis, a step that could have agricultural, medical and legal implications for this valuable crop.
Grape Waste Could Make Competitive Biofuel
The solid waste left over from wine-making could make a competitive biofuel, University of Adelaide researchers have found.
Accelerating Forage Breeding to Boost Livestock Productivity
International expert skill-sets in genomics and bioinformatics enhance our capacity to breed improved forages for Africa.
Firefly Protein Enables Visualization of Roots in Soil
A new imaging tool from a team led by Carnegie’s José Dinneny allows researchers to study the dynamic growth of root systems in soil, and to uncover the molecular signaling pathways that control such growth.
So Long, Snout
Research helps answer how birds got their beaks.
The Tree of Life — More Like A Bush
New species evolve whenever a lineage splits off into several. Because of this, the kinship between species is often described in terms of a ‘tree of life’, where every branch constitutes a species.
Algae Nutrient Recycling is a Triple Win
Sandia method cheaper, greener and cuts competition for fertilizer.
Non-Transgenic Rapeseed Product Launched For Chinese Market
Cibus and Rotam have announced a new agreement to cooperate in the development of herbicide-tolerant rapeseed in China.
TGAC Leads Development to Diminish Threat to Vietnam’s Most Important Crop
Advanced bioinformatics capabilities for next-generation rice genomics in Vietnam to aid precision breeding.
BESC Creates Microbe That Bolsters Isobutanol Production
Another barrier to commercially viable biofuels from sources other than corn has fallen with the engineering of a microbe that improves isobutanol yields by a factor of 10.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!