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Tuesday, December 23, 2014
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A novel DNA amplification method based on silicon microring resonator for rapid detection of genetic alteration in the point-of care (POC) field of cancers

Nucleic acid testing plays a critical role in molecular diagnosis[1-2]. Due to the low amounts of DNA obtained in clinical samples, the amplification of DNA is an essential step in most NAT methods [3].

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Protein Microarrays for Characterisation of the Bacillus anthracis ‘infectome’
Stephen Kidd, Karen Kempsell, Rebecca Ingram, Pierre Watteau, Daniel Altmann, Michael Elmore, Sue Charlton, Bassam Hallis and Richard Vipond

These studies provide an interesting insight into the transcriptome of virulent B. anthracis in a host infection environment.

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Effect of Heat and Cold Treatment on Germination and Early Growth Stage of Terminal Heat Tolerant (WH 730) and Intolerant (RAJ 4014) Wheat Genotypes
Om Prakash Gupta

Being second important staple food crop globally, wheat (Triticum aestivum L.) production is largely limited by heat and cold stress which adversely affects the germination, crop growth and development. Terminal heat stress is a major problem for wheat production which severely affects the grain yield.

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Kidney Genes Expression in Hypertensive ISIAH Rats
Tatyana Pylnik

The present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.

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Variation in miRNA expression between TRV-infected tobacco plants is correlated with symptom severity and TRV-16K transcripts abundance
Zhimin Yin, Krystyna Michalak, Miroslawa Chrzanowska

In the present work, expression of certain miRNAs and their targets were investigated in three tobacco plants infected with Tobacco rattle virus (TRV) isolate Deb57 collected from Northern Poland in 2008.

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Discovery of Conserved Domains for Development of Functional Markers and Identification of microRNAs from Drought Responsive Expressed Sequence Tags (ESTs) in Chickpea (Cicer arietinum L.)
Mandape M, Saikumar K, Dudhe MY, Kumar J, Meena HP, Chauhan J, Afroz A

This stidy identified that conserved domains or gene families from the ESTs could be utilized for the identification of gene-targeted markers and for development of functional markers to accelerate marker assisted backcross breeding in chickpea.

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Automated Tyrosine Kinase Inhibitor Cardiotoxicity Assay in Zebrafish
Olaia Holgado, Juan Maria Virto, Isaskun Ibarbia, Patrice Dubreuil, Didier Pez, Ainhoa Letamendia, Martine Humbert, Alain Moussy, Carles Callol-Massot

The zebrafish embryos have recently gained relevance in biomedical research thanks to some of its characteristics including embryo transparency. Combined with the possibility to adapt the model with an automatic device and the reduced cost associated to each assay, the model is an ideal killer experiment in early phases of drug discovery as well as a novel method to increase the selection arguments to reduce the candidates to enter into the Drug Development process.

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Novel, Fully Automated Method Allows Efficient Analysis of qPCR Data for Qualitative Calling Based on Comparative Cq
Collaborative research by Pioneer Hi-Bred (a DuPont company) and Azure PCR Limited

Assessment to ascertain if a method for analysis of qPCR data dependent on manual intervention can be replaced by automated analysis using the AzurePCRTM method.

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Defining off-target cleavage in a pair of Zinc Finger Nucleases
K. Mukherjee, D. Carroll

This study looks at off-target cleavage of Zinc Finger Nucleases (ZNFs) in Drosophila in an attempt to analyze potential cleavage spots, with a view to designing more efficient ZFNs.

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Showing Results 41 - 50 of 87
Scientific News
Sowing The Seeds For Improved Food Security
Research from the University of Bath has shown that it is possible to improve both seed size and seed number, opening new avenues to increase crop yields and improving food security.
Gene Critical To The Development Of Low Arsenic Plants Identified
Identification of gene could pave way for low arsenic crops such as rice.
Sequencing of Cotton A-genome Could Boost Industry
Collaboration with Bayer CropScience could translate into better commercial varieties for growers.
New Genetic Markers To Combat Yellow Rust Disease In Wheat Identified
New study released identifying genetic markers that signal resistance to the wheat yellow rust pathogen.
Crowdsourcing Science To Beat Psa
Scientists are hoping that crowdsourcing knowledge from the international science community will help them find the answer to a lethal kiwifruit disease.
Some Plants Regenerate by Duplicating their DNA
A plant’s ability to duplicate its genome within individual cells influences its ability to regenerate.
Maize Analysis Yields Whole New World of Genetic Science
Research sheds light on how chromatin is organized in a cell and how plants regulate genetic material.
Getting More Out of Nature: Genetic Toolkit Finds New Maximum for Crop Yields
An array of gene variants provides “breakthrough benefits” in tomato yield for breeders; other crops next.
New Lab Startup Afingen Uses Precision Method to Enhance Plants
Berkeley Lab breakthrough can lead to cheaper biofuels, improved crops, and new products from plants.
To Wilt or Not to Wilt
UC Riverside researchers identify new process that explains why tomatoes are susceptible to a disease-causing fungus.
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