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Automated Tyrosine Kinase Inhibitor Cardiotoxicity Assay in Zebrafish
Olaia Holgado, Juan Maria Virto, Isaskun Ibarbia, Patrice Dubreuil, Didier Pez, Ainhoa Letamendia, Martine Humbert, Alain Moussy, Carles Callol-Massot

The zebrafish embryos have recently gained relevance in biomedical research thanks to some of its characteristics including embryo transparency. Combined with the possibility to adapt the model with an automatic device and the reduced cost associated to each assay, the model is an ideal killer experiment in early phases of drug discovery as well as a novel method to increase the selection arguments to reduce the candidates to enter into the Drug Development process.

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Novel, Fully Automated Method Allows Efficient Analysis of qPCR Data for Qualitative Calling Based on Comparative Cq
Collaborative research by Pioneer Hi-Bred (a DuPont company) and Azure PCR Limited

Assessment to ascertain if a method for analysis of qPCR data dependent on manual intervention can be replaced by automated analysis using the AzurePCRTM method.

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Defining off-target cleavage in a pair of Zinc Finger Nucleases
K. Mukherjee, D. Carroll

This study looks at off-target cleavage of Zinc Finger Nucleases (ZNFs) in Drosophila in an attempt to analyze potential cleavage spots, with a view to designing more efficient ZFNs.

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Lab-on-a-Chip System for Detection of Mycotoxins in Animal Feed
S. Brunklaus, V. Stein, M. Jakubowski, M. Ritzi-Lehnert, K.S. Drese, R. Colasanto, P. Poletti

This poster introduces an automated Lab-on-a-Chip system for reliable quantitative testing of mycotoxin contamination of animal feed developed in the framework of the EU-funded project micro- FLUID.

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Polarized Cell Expansion and Heterochronic Shift in Angiosperm Spermatogenesis
Said Hafidh, Katarina Breznenova, Jana Fecikova, Vera Capkova and David Honys

This study evaluates genetic factors and common pathways in polarized cell-tip expansion.

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Identification and Characterisation of Disease Resistance Pathway Genes in Jute (Corchorus spp.)
Niaz Mahmood, Salma Sultana Alam, Rifit Ara Najnin, Nurun Nahar Fancy, Haseena Khan.

Study aims include identification and characterisation of all NBS containing genes in jute using degenerate primers designed from the conserved NBS domain, by using two species of jute; susceptible and wild type resistant varieties.

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Screening for Optimal Algal Cell Growth and Neutral Lipid Production Conditions in Microplates
Paul Held, Xavier Amouretti, Wayne Patton and Peter Banks

Algae based products offer many potential advantages over food based sources of energy, however significant research is still required in order to make them an economically viable option. To date, algal research has not extensively utilized the tool of high throughput screening using microplates that has been successfully employed in fields such as drug discovery.

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Expression of Pluripotency-determining Factors in in vitro Fertilized Buffalo Embryos and Embryonic Stem Cells
T Anand, D Kumar, M S Chauhan, and P Palta

The POU octamer-binding domain transcription factor Oct-4, Stage-specific embryonic antigens (SSEAs), and Tumor rejection antigens (TRAs), are developmentally regulated during early embryogenesis.

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In Silico Identification of Conserved Domains from EST Database in Safflower
M. Y. Dudhe, H. P. Meena, A.R.G. Ranganatha, N. Mukta and C. Lavanya

Identified conserved domains or gene families from the ESTs could be utilised for the identification of gene-targeted markers and for development of functional markers to accelerate marker assisted backcross breeding in safflower.

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Showing Results 61 - 70 of 101
Scientific News
New Genomics-Driven Surveillance To Track Crop Diseases
New genomics-driven surveillance strategy to tackle emerging and re-emerging crop pathogens that threaten global food security.
UGA Researchers Work on Creating Stress- and Disease-resistant Trees
New $490,000 grant to identify genes in trees responsible for stress tolerance.
Controlling Leaf Blotch Disease In Wheat
Scientists have found a genetic mechanism that could stop the spread of a "devastating" disease threatening wheat crops.
Multi-Gene Traits Increase Yields in Hybrid Corn Field Trials
Ceres’ results validate company's innovative approach for second-generation crop traits.
PHI-base – A Database To Protect Crop Yields And Human Health
Scientists at Rothamsted Research, in collaboration with other researchers globally have improved an Open Access internet resource that catalogues genes involved in host-pathogen interactions.
Chestnuts Roasting On An Open Fire
ORNL work with scientists funded by The American Chestnut Foundation confirms increased blight-resistance of former forest giant.
Rising Temperatures Predicted to Lower Wheat Yields
An international consortium of researchers has used big data sets to predict the effects climate change on global wheat yields.
Sowing The Seeds For Improved Food Security
Research from the University of Bath has shown that it is possible to improve both seed size and seed number, opening new avenues to increase crop yields and improving food security.
Gene Critical To The Development Of Low Arsenic Plants Identified
Identification of gene could pave way for low arsenic crops such as rice.
Sequencing of Cotton A-genome Could Boost Industry
Collaboration with Bayer CropScience could translate into better commercial varieties for growers.
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