|Automated Tyrosine Kinase Inhibitor Cardiotoxicity Assay in Zebrafish|
Olaia Holgado, Juan Maria Virto, Isaskun Ibarbia, Patrice Dubreuil, Didier Pez, Ainhoa Letamendia, Martine Humbert, Alain Moussy, Carles Callol-Massot
The zebrafish embryos have recently gained relevance in biomedical research thanks to some of its characteristics including embryo transparency. Combined with the possibility to adapt the model with an automatic device and the reduced cost associated to each assay, the model is an ideal killer experiment in early phases of drug discovery as well as a novel method to increase the selection arguments to reduce the candidates to enter into the Drug Development process.
|Novel, Fully Automated Method Allows Efficient Analysis of qPCR Data for Qualitative Calling Based on Comparative Cq|
Collaborative research by Pioneer Hi-Bred (a DuPont company) and Azure PCR Limited
Assessment to ascertain if a method for analysis of qPCR data dependent on manual intervention can be replaced by automated analysis using the AzurePCRTM method.
|Defining off-target cleavage in a pair of Zinc Finger Nucleases|
K. Mukherjee, D. Carroll
This study looks at off-target cleavage of Zinc Finger Nucleases (ZNFs) in Drosophila in an attempt to analyze potential cleavage spots, with a view to designing more efficient ZFNs.
|Lab-on-a-Chip System for Detection of Mycotoxins in Animal Feed|
S. Brunklaus, V. Stein, M. Jakubowski, M. Ritzi-Lehnert, K.S. Drese, R. Colasanto, P. Poletti
This poster introduces an automated Lab-on-a-Chip system for reliable quantitative testing of mycotoxin contamination of animal feed developed in the framework of the EU-funded project micro- FLUID.
|Polarized Cell Expansion and Heterochronic Shift in Angiosperm Spermatogenesis|
Said Hafidh, Katarina Breznenova, Jana Fecikova, Vera Capkova and David Honys
This study evaluates genetic factors and common pathways in polarized cell-tip expansion.
| Identification and Characterisation of Disease Resistance Pathway Genes in Jute (Corchorus spp.)|
Niaz Mahmood, Salma Sultana Alam, Rifit Ara Najnin, Nurun Nahar Fancy, Haseena Khan.
Study aims include identification and characterisation of all NBS containing genes in jute using degenerate primers designed from the conserved NBS domain, by using two species of jute; susceptible and wild type resistant varieties.
|Screening for Optimal Algal Cell Growth and Neutral Lipid Production Conditions in Microplates|
Paul Held, Xavier Amouretti, Wayne Patton and Peter Banks
Algae based products offer many potential advantages over food based sources of energy, however significant research is still required in order to make them an economically viable option. To date, algal research has not extensively utilized the tool of high throughput screening using microplates that has been successfully employed in fields such as drug discovery.
|Expression of Pluripotency-determining Factors in in vitro Fertilized Buffalo Embryos and Embryonic Stem Cells|
T Anand, D Kumar, M S Chauhan, and P Palta
The POU octamer-binding domain transcription factor Oct-4, Stage-specific embryonic antigens (SSEAs), and Tumor rejection antigens (TRAs), are developmentally regulated during early embryogenesis.
|In Silico Identification of Conserved Domains from EST Database in Safflower|
M. Y. Dudhe, H. P. Meena, A.R.G. Ranganatha, N. Mukta and C. Lavanya
Identified conserved domains or gene families from the ESTs could be utilised for the identification of gene-targeted markers and for development of functional markers to accelerate marker assisted backcross breeding in safflower.