The Apollo 324™ is a benchtop system that automates next-generation sequence library preparation workflows by using bead technology to execute high-performance isolation and purification of nucleic acids (DNA, RNA, plasmid and so on) and proteins. The system automates end-repair, A-tail addition, adapter ligation and final double-bead-based cleanup and size selection. The Apollo 324 enables simultaneous processing of one to eight samples, with batch processing for 32 samples at a time. Up to eight samples can be prepared in approximately four hours, yielding products ready for amplification or direct sequencing, and a batch of 32 libraries can be created in less than eight hours.
IntegenX reagent kits are validated to optimize overall system performance. Reagent kits are available for the Illumina® Genome Analyzer and HiSeq™ 2000 NGS systems, with other kits due shortly to automate sample preparation for a variety of applications and platforms.