Corporate Banner
Satellite Banner
Biologics & Bioprocessing
Scientific Community
Become a Member | Sign in
Home>News>This Article

Helmedix Launched with Start-up Investment from the MRCF

Published: Monday, July 01, 2013
Last Updated: Monday, July 01, 2013
Bookmark and Share
Company will develop therapeutic peptide drugs for the prevention and treatment of autoimmune disease.

Helmedix Pty Ltd was launched with start-up financing from Australia’s Medical Research Commercialization Fund (MRCF).

Based on intellectual property from the University of Technology Sydney (UTS)’s ithree institute, Helmedix will develop therapeutic peptide drugs for the prevention and treatment of autoimmune disease.

The ithree Institute research team led by Dr Sheila Donnelly has identified a number of immune modulating peptides derived from helminth parasites, one of which is effective in suppressing the inflammatory response of the host and has shown therapeutic potential in a mouse model of type 1 diabetes.

The immune modulating activity of these peptides indicates potential broader application in a variety other autoimmune diseases.

The MRCF has committed AU$1.25 million to progress lead optimization and pre-clinical development of the immune modulating peptides over the next two years.

Subject to meeting milestones, Helmedix will seek further investment or industry partnerships to move the helminth-derived peptides through clinical development as a treatment for autoimmune and inflammatory diseases.

Commenting on the new company, Stephen Thompson, Director of Helmedix and Partner at Brandon Capital, the venture capital firm that manages the MRCF, said “Helmedix is a great example of the type of early stage opportunity that the MRCF is set up to support. Its discoveries have broad potential to impact a number of autoimmune diseases and we look forward to working with the team to progress the technology further towards commercial development.”

Professor Ian Charles, Director of the UTS ithree institute, said that the institute’s significant expertise in infectious diseases caused by bacterial, viruses and parasites was helping understand the way in which the helminth parasite evades the sophisticated immune defence systems of its host, continuing “Understanding the mechanism by which the helminth parasites can persist in their host by regulating the immune system, and applying these mechanisms to the development of therapeutics for the prevention or treatment of autoimmune and inflammatory diseases, has huge potential.”

This is the first investment by MRCF in technology emerging from the ithree institute. The institute was launched in 2010 and joined the MRCF in 2011.

Commercialization of ithree’s technology is managed by UTS’s commercialization partner UniQuest, who led the effort to attract investment by MRCF into Helmedix.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
"Good" Mozzie Virus Might Hold Key to Fighting Human Disease
Australian scientists have discovered a new virus carried by one of the country’s most common pest mosquitoes.
World’s First Therapeutic Venom Database
Open-source library describes nearly 43,000 effects on the human body.
Speeding Up the Process of Making Vaccines
System uses a freeze-dry concept to develop "just-add-water" solution.
Surprising Trait Found in Anti-HIV Antibodies
Scientists at The Scripps Research Institute (TSRI) have new weapons in the fight against HIV.
New Method Identifies Up to Twice as Many Proteins and Peptides
An international team of researchers developed a method that identifies up to twice as many proteins and peptides in mass spectrometry data than conventional approaches.
The Do’s and Don’ts of SPR Experiments
Surface Plasmon Resonance (SPR) is a technique that is becoming more widely used, particularly by anyone who wants to obtain accurate on (association) and off (dissociation) rates for biomolecular binding.
Genetically Engineering Algae to Kill Cancer Cells
New interdisciplinary research has revealed the frontline role tiny algae could play in the battle against cancer, through the innovative use of nanotechnology.
Novel Stem Cell Line Avoids Risk of Introducing Transplanted Tumors
Progenitor cells might eventually be used to repair or rebuild damaged or destroyed organs.
Single Vaccine for Chikungunya, Related Viruses May be Possible
What if a single vaccine could protect people from infection by many different viruses? That concept is a step closer to reality.
Blocking the Transmission Of Malaria Parasites
Vaccine candidate administered for the first time in humans in a phase I clinical trial led by Oxford University’s Jenner Institute, with partners Imaxio and GSK.

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos