Corporate Banner
Satellite Banner
Biologics & Bioprocessing
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Bio-Rad Launches the Biologics Analysis Workflow™ with the GS-900™ Calibrated Densitometer

Published: Thursday, July 18, 2013
Last Updated: Thursday, July 18, 2013
Bookmark and Share
Bio-Rad Laboratories launches the new Biologics Analysis Workflow for faster, easier, and more reproducible purity assessment of protein-based therapeutics in cGMP-regulated environments.

The Biologics Analysis Workflow combines the release of several new products — the GS-900 calibrated densitometer, Image Lab™ 5.0 software, and QC Colloidal Coomassie stain — with Bio-Rad’s Criterion™ precast gels and Precision Plus Protein™ standards.

BioRad_Biologics_Analysis.gif
 
How It Works
The Biologics Analysis Workflow consists of the following steps:

1. Separate samples in only 20 minutes using Criterion™ TGX™ precast gels. The higher-throughput, mid-sized format increases reproducibility and reduces costs because fewer gels are needed.
 
2.   Stain proteins with the QC Colloidal Coomassie stain. Capable of detecting nanograms of protein, this ready-to-use stain eliminates the need for preparation, requiring no additional reagents or mixing, which results in increased reproducibility.
 
3.    Visualize proteins using the GS-900 calibrated densitometer. Autocalibration prior to each run ensures consistency and accuracy. The wide dynamic range improves purity estimates by allowing for impurity detection at low optical density (OD).
 
4.    Analyze results using the new Image Lab 5.0 software. Designed to meet U.S. FDA 21 CFR part 11 compliance requirements, Image Lab automates gel analysis, saving time and ensuring consistency between runs.
 
A scientist at a global contract research organization (CRO) explains that the ability to calibrate the GS-900 system prior to scanning and take the optical density down to zero offers a significant advantage regarding compliance, because the GS-900 densitometer covers the density range that the CRO reports. He adds that Image Lab software facilitates compliance by allowing easy creation of the sorts of custom data reports that auditors look for.

A recent comparability study by Bio-Rad demonstrates how easily labs can update their protocols to include the GS-900 system and the Biologics Analysis Workflow for compliance with FDA and other regulatory requirements.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
‘Cellbots’ Chase Down Cancer, Deliver Drugs Directly to Tumors
Programmable T cells shown to be versatile, precise, and powerful in lab studies.
Monkeys Protected by Zika DNA Vaccine
Experimental Zika virus DNA vaccines successfully protected monkeys against Zika infection.
New Weapon Against Hard-to-Treat Bacterial Infections
Using peptides, researchers have been able to prevent drug-resistance bacteria from forming abscesses.
Tapping Evolution to Improve Biotech Products
Researchers show how 'ancestral sequence reconstruction' can be used to guide engineering of a blood clotting protein.
Antibodies Paving the Way to HIV Vaccine
Researchers uncover factors responsible for the formation of broadly neutralizing HIV antibodies in humans.
Vaccine Against Common Cold Achievable
Researchers suggest that a vaccine against rhinoviruses is possible using variant virus vaccines.
Treating Sepsis with Marine Mitochondria
Mitochondrial alternative oxidase from a marine animal combats bacterial sepsis.
Biomolecular Manufacturing ‘On-the-Go’
Wyss Institute team unveils a low-cost, portable method to manufacture biomolecules for a wide range of vaccines, other therapies as well as diagnostics.
Molecular Switch Aids Immune Therapy
Researchers identify strategy to maximise effectiveness of immune therapy through molecular switch controlling immune suppression.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!