Corporate Banner
Satellite Banner
Biologics & Bioprocessing
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Bio-Rad Launches the Biologics Analysis Workflow™ with the GS-900™ Calibrated Densitometer

Published: Thursday, July 18, 2013
Last Updated: Thursday, July 18, 2013
Bookmark and Share
Bio-Rad Laboratories launches the new Biologics Analysis Workflow for faster, easier, and more reproducible purity assessment of protein-based therapeutics in cGMP-regulated environments.

The Biologics Analysis Workflow combines the release of several new products — the GS-900 calibrated densitometer, Image Lab™ 5.0 software, and QC Colloidal Coomassie stain — with Bio-Rad’s Criterion™ precast gels and Precision Plus Protein™ standards.

BioRad_Biologics_Analysis.gif
 
How It Works
The Biologics Analysis Workflow consists of the following steps:

1. Separate samples in only 20 minutes using Criterion™ TGX™ precast gels. The higher-throughput, mid-sized format increases reproducibility and reduces costs because fewer gels are needed.
 
2.   Stain proteins with the QC Colloidal Coomassie stain. Capable of detecting nanograms of protein, this ready-to-use stain eliminates the need for preparation, requiring no additional reagents or mixing, which results in increased reproducibility.
 
3.    Visualize proteins using the GS-900 calibrated densitometer. Autocalibration prior to each run ensures consistency and accuracy. The wide dynamic range improves purity estimates by allowing for impurity detection at low optical density (OD).
 
4.    Analyze results using the new Image Lab 5.0 software. Designed to meet U.S. FDA 21 CFR part 11 compliance requirements, Image Lab automates gel analysis, saving time and ensuring consistency between runs.
 
A scientist at a global contract research organization (CRO) explains that the ability to calibrate the GS-900 system prior to scanning and take the optical density down to zero offers a significant advantage regarding compliance, because the GS-900 densitometer covers the density range that the CRO reports. He adds that Image Lab software facilitates compliance by allowing easy creation of the sorts of custom data reports that auditors look for.

A recent comparability study by Bio-Rad demonstrates how easily labs can update their protocols to include the GS-900 system and the Biologics Analysis Workflow for compliance with FDA and other regulatory requirements.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Developing a More Precise Seasonal Flu Vaccine
During the 2014-15 flu season, the poor match between the virus used to make the world’s vaccine stocks and the circulating seasonal virus yielded a vaccine that was less than 20 percent effective.
Fighting Cancer with Borrowed Immunity
A new step in cancer immunotherapy: researchers from the Netherlands Cancer Institute and University of Oslo/Oslo University Hospital show that even if one's own immune cells cannot recognize and fight their tumors, someone else's immune cells might.
Modified Microalgae Converts Sunlight into Valuable Medicine
A special type of microalgae can soon produce valuable chemicals such as cancer treatment drugs and much more just by harnessing energy from the sun.
Immune Cells Remember Their First Meal
Scientists at the University of Bristol have identified the trigger for immune cells' inflammatory response – a discovery that may pave the way for new treatments for many human diseases.
Paper Filter Can Remove Viruses from Water
A new paper filter can purify water from viruses, even the most difficult and contagious.
Large-scale HIV Vaccine Trial to Launch in South Africa
NIH-funded study will test safety, efficacy of vaccine regimen.
New HIV Vaccine Target Discovered
NIH-Led team have discovered a new vaccine target site on HIV.
Mimicking Evolution to Create Novel Proteins
A study by researchers in the Kuhlman lab offers a new route to design the 'cellular machines' needed to understand and battle diseases.
Antibody Therapy Opens Door to Potential New Treatment for HIV
Researchers at Rockefeller University show how a broadly neutralizing antibody could be used to help fight HIV.
Investigational Malaria Vaccine Protects Healthy U.S. Adults
Researchers at NIH have found that the malaria vaccine protected a small number of healthy, malaria-naïve adults in the U.S. from infection for more than one year after immunization.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!