Corporate Banner
Satellite Banner
Biologics & Bioprocessing
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Redbiotec, GE Healthcare CMV Vaccine Collaboration

Published: Tuesday, August 05, 2014
Last Updated: Tuesday, August 05, 2014
Bookmark and Share
Companies combine expertise to produce cytomegalovirus vaccine candidates.

Redbiotec has successfully applied its unique expertise and innovative technology platform to complete a collaborative program with global multinational, GE Healthcare Life Sciences. Using GE Healthcare's single-use WAVE Bioreactor and ReadyToProcess crossflow filtration system, the team developed a novel process for the production, clarification, and concentration of cytomegalovirus-like particles. Results from the study have recently been published1, further substantiating the value of the Redbiotec rePAX® platform for the development and production of new vaccines against cytomegalovirus (CMV).
 
Redbiotec uses its proprietary rePAX® co-expression technology for the efficient generation of multi-component virus-like particles (VLPs) and other protein assemblies. This technology is effectively applied to both in-house and external co-development programs, supporting the company’s mission to discover and develop novel, effective vaccines against the highly prevalent influenza and herpes viruses.
 
Commenting on the collaboration, Jakob Liderfelt, Section Manager Cell Culture, LS Bio Process GE Healthcare Life Sciences, said, “GE Healthcare Life Sciences seeks to collaborate with world-wide biotechnology leaders such as Redbiotec to help drive disease research forward. We are looking forward to continuing our work with the company to help advance their CMV program using our next-generation WAVE Bioreactor system. This system was specifically developed to enable the fast and scalable production of biopharmaceuticals such as Redbiotec’s virus-like particles."
Christian Schaub, CEO of Redbiotec commented, “Our unique rePAX® technology allows us to successfully replicate viral structures or even whole viruses. Importantly, these natural, virus-like particles (reVLPs®) are functional but non-replicating, rendering them non-hazardous and allowing us to apply them to vaccine development. The vaccine will then stimulate an immune response without causing infectious disease.” He continued, ”Collaborations such as this project with GE Healthcare enable us to develop CMV-like particles and soluble CMV protein complexes at an industrial scale for the pre-clinical and clinical trials of vaccines.”
 
This latest news follows recent partnership announcements with Roche, GSK and Merck, positioning Redbiotec as an important innovator in the development of novel vaccines to alleviate unmet medical needs and improve the lives of patients. To learn more, visit www.redbiotec.ch.
 
1 Vicente T, Burri S, Wellnitz S, Walsh K, Rothe S, Liderfelt J (2014) Fully aseptic single-use cross flow filtration system for clarification and concentration of cytomegalovirus-like particles; Engineering in Life Sciences 14:318–26.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
First Artificial Ribosome Designed
Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell.
Experimental MERS Vaccine Shows Promise in Animal Studies
A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines.
Sweet Revenge Against Superbugs
A special type of synthetic sugar could be the latest weapon in the fight against superbugs.
Researchers Develop Vaccine that Protects Primates Against Ebola
A collaborative team from The University of Texas Medical Branch at Galveston and the National Institutes of Health have developed an inhalable vaccine that protects primates against Ebola.
Universal Flu Vaccine in the Works
A new study has demonstrated a potential strategy for developing a flu vaccine with potent, broad protection.
Immunotherapy Shows Promise for Myeloma
A strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
Ferring Bets on Bacteriophages to Treat Inflammatory Bowel Disease
Ferring Pharmaceuticals have annoucned that it will collaborate with Intralytix in the latest phase of its early stage development programme for a bacteriophage-based therapy for inflammatory bowel disease (IBD).
A Novel Drug to FIght Malaria
An international team of scientists has announced that a new compound to fight malaria is ready for human trials.
Ebola Vaccine Trial Begins in Senegal
A clinical trial to evaluate an Ebola vaccine has begun in Dakar, Senegal, after initial research started at the Jenner Institute, Oxford University.
New Cell Structure Finding Might Lead to Novel Cancer Therapies
University of Warwick scientists in the U.K. say they have discovered a cell structure which could help researchers understand why some cancers develop.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!