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 | Helping you to shape in vitro models with cell-based assays Christian Oberdanner, Ph.D. Marketing Application Specialist Detection for Tecan Austria |
 | The Isolation and Characterization of Brain Metastasis – Competent Breast Cancer CTCs Dario Marchetti, Professor/Director, Baylor College of Medicine, speaking at CellTech 2013. |
Cell Migration Assays Trends
HTStec
This market report summarizes the results of HTStec’s global web-based benchmarking survey on cell migration, motility or invasion assays carried out in July 2012.
Manufacturing of Vaccines - Cell Culture Technology Gradually Replacing Egg-Based Manufacturing
GBI Research
This report provides insights into the production methods of vaccines and into vaccine production capacity. The report discusses the egg-based and cell culture-based vaccine manufacturing processes in depth. Furthermore, details of the whole process throughput and the technologies used in vaccine manufacturing are provided in the report.
Diseased Primary Cells Trends
HTStec
This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on diseased primary cells and in vitro models of disease carried out in November 2010.
3D Cell Culture Trends
HTStec
This market report summarizes the results of HTStec’s second industry-wide global web-based benchmarking survey on three dimensional (3D) cell culture carried out in October 2011.
HTStec
This market report summarizes the results of HTStec’s global web-based benchmarking survey on cell migration, motility or invasion assays carried out in July 2012.
Manufacturing of Vaccines - Cell Culture Technology Gradually Replacing Egg-Based Manufacturing
GBI Research
This report provides insights into the production methods of vaccines and into vaccine production capacity. The report discusses the egg-based and cell culture-based vaccine manufacturing processes in depth. Furthermore, details of the whole process throughput and the technologies used in vaccine manufacturing are provided in the report.
Diseased Primary Cells Trends
HTStec
This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on diseased primary cells and in vitro models of disease carried out in November 2010.
3D Cell Culture Trends
HTStec
This market report summarizes the results of HTStec’s second industry-wide global web-based benchmarking survey on three dimensional (3D) cell culture carried out in October 2011.
Developmental Protein Plays Role in Spread of Cancer
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating metastasis.
Silk and Cellulose Biologically Effective for Use in Stem Cell Cartilage Repair
Over 20 million people in Europe suffer from osteoarthritis which can lead to extensive damage to the knee and hip cartilage.
Symposium to Focus on Advancements in Organ-on-a-Chip Research
Research teams from Purdue University's Discovery Park and the Korean Institute of Science and Technology will meet May 16.
Isolation and Culture of Smooth Muscle Cells from Human Acute type A Aortic Dissection
The aim of this work was to investigate whether the SMCs of acute TAAD could be isolated and cultured for further research.
Effects of 3-D Microwell Culture on Growth Kinetics and Metabolism of Human Embryonic Stem Cells
3-D culture systems have been utilized to enhance growth or differentiation of these hESCs by better mimicking the 3-D nature of in vivo tissue development than standard 2-D systems.
Unanticipated Consequences of DNA Hypomethylation; Loss and Gain of Polycomb Mediated Transcription Repression in Somatic Cells
By genome-wide mapping of the Polycomb Repressive Complex 2 (PRC2)-signature histone mark, H3K27me3, in DNA methylation-deficient mouse somatic cells, the Meehan lab shows that loss of DNA methylation is coincident with widespread H3K27me3 redistribution.
Patients’ Skin Cells are Transformed into Heart Cells to Create a ‘Disease-In-A-Dish’
Lab model of an inherited, life-threatening disease known as ARVD/C allows researchers to study the condition and find ways to treat it.
3D Printed Human Organs for Testing and Transplantation
Process could pave the way to purpose-built replacement organs for patients, eliminating the need for organ donation, immune suppression and the problem of transplant rejection.
A Better Way to Culture Central Nervous Cells
A protein associated with neuron damage in Alzheimer's patients provides a superior scaffold for growing central nervous system cells in the lab.
Maglev Tissues Could Speed Toxicity Tests
Scientists use magnetic levitation to make in vitro lung tissue more realistic.
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating metastasis.
Silk and Cellulose Biologically Effective for Use in Stem Cell Cartilage Repair
Over 20 million people in Europe suffer from osteoarthritis which can lead to extensive damage to the knee and hip cartilage.
Symposium to Focus on Advancements in Organ-on-a-Chip Research
Research teams from Purdue University's Discovery Park and the Korean Institute of Science and Technology will meet May 16.
Isolation and Culture of Smooth Muscle Cells from Human Acute type A Aortic Dissection
The aim of this work was to investigate whether the SMCs of acute TAAD could be isolated and cultured for further research.
Effects of 3-D Microwell Culture on Growth Kinetics and Metabolism of Human Embryonic Stem Cells
3-D culture systems have been utilized to enhance growth or differentiation of these hESCs by better mimicking the 3-D nature of in vivo tissue development than standard 2-D systems.
Unanticipated Consequences of DNA Hypomethylation; Loss and Gain of Polycomb Mediated Transcription Repression in Somatic Cells
By genome-wide mapping of the Polycomb Repressive Complex 2 (PRC2)-signature histone mark, H3K27me3, in DNA methylation-deficient mouse somatic cells, the Meehan lab shows that loss of DNA methylation is coincident with widespread H3K27me3 redistribution.
Patients’ Skin Cells are Transformed into Heart Cells to Create a ‘Disease-In-A-Dish’
Lab model of an inherited, life-threatening disease known as ARVD/C allows researchers to study the condition and find ways to treat it.
3D Printed Human Organs for Testing and Transplantation
Process could pave the way to purpose-built replacement organs for patients, eliminating the need for organ donation, immune suppression and the problem of transplant rejection.
A Better Way to Culture Central Nervous Cells
A protein associated with neuron damage in Alzheimer's patients provides a superior scaffold for growing central nervous system cells in the lab.
Maglev Tissues Could Speed Toxicity Tests
Scientists use magnetic levitation to make in vitro lung tissue more realistic.
ZEISS to Acquire Xradia to Complement its Microscopy Business
Expanding from light and electron microscopy into X-ray microscopy solutions.
Boehringer Ingelheim Pioneers Biopharmaceuticals Move to China
First international company using cell culture technology to produce biopharmaceuticals in China.
Asylum Announces Ben Ohler as AFM Business Manager
Ohler will oversee the Company’s MFP-3D family of products.
EMD Millipore and PharmaCell Announces Collaboration
Collaboration to evaluate EMD Millipore’s Mobius® bioreactor platform for expansion of HepaRG® cells.
Leica Microsystems and Leica Biosystems Strengthen Market Position in Brazil
Long-standing Leica distributors Aotec have been acquired.
Fujifilm Diosynth Biotechnologies Commissions New Cell Banking Facility
Fujifilm Diosynth Biotechnologies has commissioned on time its new mammalian cGMP Cell Banking Facility (CBF) at its Billingham, UK site.
DSM Announces Opening of New cGMP Biopharmaceutical Manufacturing Operation
Company announced that their new cGMP custom biopharmaceutical manufacturing 'biologics plant of the future' will open in Brisbane, Australia, in June 2013.
Thermo Fisher Scientific to Acquire Life Technologies Corporation
The definitive agreement will see Thermo Fisher will acquire Life Technologies for $76.00 in cash per fully diluted common share or approximately $13.6 billion.
Pall to Open Latest Life Sciences Centre of Excellence in Portsmouth (UK)
The Centre of Excellence (COE) will offer a full suite of capabilities including cell culture, purification, analytical solutions, protein characterization and microbiological tools.
Asylum Research Appoints Amir Moshar
Company appoints Amir to west coast US technical sales.
Expanding from light and electron microscopy into X-ray microscopy solutions.
Boehringer Ingelheim Pioneers Biopharmaceuticals Move to China
First international company using cell culture technology to produce biopharmaceuticals in China.
Asylum Announces Ben Ohler as AFM Business Manager
Ohler will oversee the Company’s MFP-3D family of products.
EMD Millipore and PharmaCell Announces Collaboration
Collaboration to evaluate EMD Millipore’s Mobius® bioreactor platform for expansion of HepaRG® cells.
Leica Microsystems and Leica Biosystems Strengthen Market Position in Brazil
Long-standing Leica distributors Aotec have been acquired.
Fujifilm Diosynth Biotechnologies Commissions New Cell Banking Facility
Fujifilm Diosynth Biotechnologies has commissioned on time its new mammalian cGMP Cell Banking Facility (CBF) at its Billingham, UK site.
DSM Announces Opening of New cGMP Biopharmaceutical Manufacturing Operation
Company announced that their new cGMP custom biopharmaceutical manufacturing 'biologics plant of the future' will open in Brisbane, Australia, in June 2013.
Thermo Fisher Scientific to Acquire Life Technologies Corporation
The definitive agreement will see Thermo Fisher will acquire Life Technologies for $76.00 in cash per fully diluted common share or approximately $13.6 billion.
Pall to Open Latest Life Sciences Centre of Excellence in Portsmouth (UK)
The Centre of Excellence (COE) will offer a full suite of capabilities including cell culture, purification, analytical solutions, protein characterization and microbiological tools.
Asylum Research Appoints Amir Moshar
Company appoints Amir to west coast US technical sales.
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Chia-Hsun Hsieh and Sanger Hung-Chih Lin win at CellTech 2012
Chang Gung University
Chia-Hsun Hsieh and Sanger Hung-Chih Lin win at CellTech 2012
Determination and Comparison of Specifics of Nucleus Pulposus Cells of Human Intervertebral Disc in Alginate and Chitosan– Gelatin Scaffolds
Tehran University of Medical Sciences
In this work we studied specefices of NP cells obtained from nucleus pulposus by collagenase enzymatic hydrolysis obtained from patients undergoing open surgery.
Transporter-based In Vitro-In Vivo Extrapolation (IVIVE)
F. Hoffman-La Roche Ltd.
Mechanistic analysis of in vitro measurements to obtain values of kinetic parameters for drug interactions with transporters, as well as for passive diffusion through cell membranes.
The Mesenchymal Stem Cells Bioengineered Tissue Using Cobalt-60 Radiation
IPEN/CNEN - USP
The biological effects of gamma radiation by cobalt-60 sources on epidermal-dermal matrix have not been fully elucidated when mesenchymal stem cells cultured add in. This poster shows how scientists standardized the keratinocytes and adipose-derived stem cell (ADSC) culture procedure before constructing a bioengineered dermal-epidermal equivalent populated by keratinocytes and ADSC cultured cells.
Effect of Culture Media and Serum Supplementation on the Development of in vitro Fertilized Buffalo Embryos
Central Institute for Research on Buffaloes
This poster compares the development of buffalo embryos in simple and complex culture media and aims to determine the effects of serum supplementation on the development of buffalo embryos.
An Emerging Revolution in Automated 3D Cell Culture
Merck Research Laboratories,University of Virginia, BioCell Cubed
Market pressure exists for new paradigms to meet the demands for more rapid and reproducible cell production to keep up with advances in cell-based assays used in drug discovery and development. Novel automation platforms enable high productivity on three dimensional surfaces.
Chang Gung University
Chia-Hsun Hsieh and Sanger Hung-Chih Lin win at CellTech 2012
Determination and Comparison of Specifics of Nucleus Pulposus Cells of Human Intervertebral Disc in Alginate and Chitosan– Gelatin Scaffolds
Tehran University of Medical Sciences
In this work we studied specefices of NP cells obtained from nucleus pulposus by collagenase enzymatic hydrolysis obtained from patients undergoing open surgery.
Transporter-based In Vitro-In Vivo Extrapolation (IVIVE)
F. Hoffman-La Roche Ltd.
Mechanistic analysis of in vitro measurements to obtain values of kinetic parameters for drug interactions with transporters, as well as for passive diffusion through cell membranes.
The Mesenchymal Stem Cells Bioengineered Tissue Using Cobalt-60 Radiation
IPEN/CNEN - USP
The biological effects of gamma radiation by cobalt-60 sources on epidermal-dermal matrix have not been fully elucidated when mesenchymal stem cells cultured add in. This poster shows how scientists standardized the keratinocytes and adipose-derived stem cell (ADSC) culture procedure before constructing a bioengineered dermal-epidermal equivalent populated by keratinocytes and ADSC cultured cells.
Effect of Culture Media and Serum Supplementation on the Development of in vitro Fertilized Buffalo Embryos
Central Institute for Research on Buffaloes
This poster compares the development of buffalo embryos in simple and complex culture media and aims to determine the effects of serum supplementation on the development of buffalo embryos.
An Emerging Revolution in Automated 3D Cell Culture
Merck Research Laboratories,University of Virginia, BioCell Cubed
Market pressure exists for new paradigms to meet the demands for more rapid and reproducible cell production to keep up with advances in cell-based assays used in drug discovery and development. Novel automation platforms enable high productivity on three dimensional surfaces.
Direct Visualisation, Sizing and Counting of Aggregation in Proteins
NanoSight Ltd
Characterising the state of aggregation in proteins is of paramount importance when trying to understand biopharmaceutical product stability and efficacy. Product quality, both in terms of biological activity and immunogenicity can be highly influenced by the state of protein aggregation.
Automated Growth Monitoring of Microaerophilic Organisms
Tecan Group - Products
Walkaway growth monitoring of Helicobacter pylori in the Infinite® 200 PRO reader with Gas Control Module (GCM™).
Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library
BioTek Instruments
Here we demonstrate the detection of GLP-1R binding through the incorporation of a homogeneous cell-based binding assay using HTRF Tag-lite® technology.
Analyzing Biological Samples
Tecan
This technical note describes the capability of Tecan’s Infinite® 200 PRO multimode reader to regulate the CO2 partial pressure inside its measurement chamber.
Advanced TC™: A Novel Cell Culture Surface Improving the Cultivation and Differentiation of Embryonic Stem Cells
Greiner Bio-One GmbH
The importance of embryonic stem cells rests in their lack of specialisation. These basic cells are present in the earliest stages of developing embryos and are able to develop into virtually any type of cell and tissue in the body.
ESGRO-2i Medium: Inhibitor-Based Serum-free Medium for ES and iPS Cell Culture
Millipore
Defined serum-free and feeder-free culture of mouse embryonic stem (mES) cells holds many advantages over the classical serum-containing feeder-dependent culture methods, ranging from decreased lot-to-lot variations to ease of culture.
PSVue®: Novel small molecule probes for fluorescent imaging of apoptosis and bacterial infections in vitro and in vivo
MTTI
PSVue® offers a robust alternative to probes currently used by researchers to detect early-to-mid stage apoptosis, as well as bacterial infections.
Applications of rapid immunoassays (FAST ILA) in cell culture/fermentation and process development using the Threshold System
Molecular Devices
Accurate measurement of the concentration of a biological product is important in bioreactor/fermenter monitoring, downstream processing and final product quality control. Currently, electrophoretic, chromatographic and immunochemical methods are the most commonly used. These three methods are currently used in combination to provide the desired sample information.
NanoSight Ltd
Characterising the state of aggregation in proteins is of paramount importance when trying to understand biopharmaceutical product stability and efficacy. Product quality, both in terms of biological activity and immunogenicity can be highly influenced by the state of protein aggregation.
Automated Growth Monitoring of Microaerophilic Organisms
Tecan Group - Products
Walkaway growth monitoring of Helicobacter pylori in the Infinite® 200 PRO reader with Gas Control Module (GCM™).
Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library
BioTek Instruments
Here we demonstrate the detection of GLP-1R binding through the incorporation of a homogeneous cell-based binding assay using HTRF Tag-lite® technology.
Analyzing Biological Samples
Tecan
This technical note describes the capability of Tecan’s Infinite® 200 PRO multimode reader to regulate the CO2 partial pressure inside its measurement chamber.
Advanced TC™: A Novel Cell Culture Surface Improving the Cultivation and Differentiation of Embryonic Stem Cells
Greiner Bio-One GmbH
The importance of embryonic stem cells rests in their lack of specialisation. These basic cells are present in the earliest stages of developing embryos and are able to develop into virtually any type of cell and tissue in the body.
ESGRO-2i Medium: Inhibitor-Based Serum-free Medium for ES and iPS Cell Culture
Millipore
Defined serum-free and feeder-free culture of mouse embryonic stem (mES) cells holds many advantages over the classical serum-containing feeder-dependent culture methods, ranging from decreased lot-to-lot variations to ease of culture.
PSVue®: Novel small molecule probes for fluorescent imaging of apoptosis and bacterial infections in vitro and in vivo
MTTI
PSVue® offers a robust alternative to probes currently used by researchers to detect early-to-mid stage apoptosis, as well as bacterial infections.
Applications of rapid immunoassays (FAST ILA) in cell culture/fermentation and process development using the Threshold System
Molecular Devices
Accurate measurement of the concentration of a biological product is important in bioreactor/fermenter monitoring, downstream processing and final product quality control. Currently, electrophoretic, chromatographic and immunochemical methods are the most commonly used. These three methods are currently used in combination to provide the desired sample information.
