Corporate Banner
Satellite Banner
Cell Culture
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Transparent Corporation of Japan, and Molecular Response Sign Key Collaboration and Supply Agreement

Published: Tuesday, March 27, 2012
Last Updated: Tuesday, March 27, 2012
Bookmark and Share
Collaboration to launch novel ex-vivo 3D cell culture system with a focus on oncology applications.

Under the terms, parties will jointly introduce a novel 3-dimensional cell culture system based on TRP’s patented 3D cell culture plate design and manufacturing technologies, and MRL’s proprietary bank of ‘living’ tumor cells and quantitative high content platforms. The platform will be marketed under TRP’s “Cell-able Oncology(TM)” brand with key contract research support for preclinical and clinical trial applications by MRL.

Current strategies for developing new anticancer drugs rely heavily on preclinical testing in cancer cell lines and their derived in-vivo xenograft models. A significant limitation to current preclinical testing is the use of highly passaged cancer cell lines grown on plastic.
Improved preclinical models are required to advance our understanding of the molecular aberrations that underpin cancer and are critical for developing and deploying targeted therapies to improve patients’ lives.

Cell-able Oncology(TM) allows primary tumor cells to grow in 3-dimensional cultures that more closely resemble in-vivo like conditions. Models grown in 3-dimensional culture conditions coupled with molecular characterization provide a stronger correlation to clinical outcomes than conventional preclinical anticancer drug testing.

“We are very pleased to collaborate with Molecular Response to provide key enabling technologies to pharmaceutical researchers and medical professionals by introducing Cell-able Oncology(TM),” said Transparent CEO Rocky Kato. “Transparent and Molecular Response will present collaborative research outcomes at the AACR Annual Meeting to be held in Chicago from March 31 to April 4, 2012. Molecular Response pharmaceutical research services combined with Cell-able Oncology(TM) will provide researchers the right tools to perform transformative drug discovery with patient-derived primary tumor cells and focused molecular targets that enable drug sensitivity testing that is strongly correlated to clinical outcomes.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Common Cell Transformed into Master Heart Cell
By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin—Madison have generated master heart cells — primitive progenitors that form the developing heart.
Mitochondria Shown to Trigger Cell Ageing
An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.
Cancer Cells Kill Off Healthy Neighbours
Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.
Editing of Embryos Approved in the UK
The Human Fertilisation and Embryology Authority (HFEA) has approved a research application from the Francis Crick Institute to use new "gene editing" techniques on human embryos.
Microbes Take Their Vitamins
Scientists exploit organisms' needs in order to track 'vitamin mimics' in bacteria.
Machine Learning Uncovers Unknown Bacterial Features
Technique robustly identified characteristic gene expression patterns in response to antibiotics, low oxygen conditions.
CRISPR-Cas9 Gene Editing Advances Again
UC Berkeley researchers have made a major improvement in CRISPR-Cas9 technology that achieves an unprecedented success rate of 60 percent when replacing a short stretch of DNA with another.
Disrupting Cell’s Supply Chain Freezes Cancer Virus
When the cancer-causing Epstein-Barr virus moves into a B-cell of the human immune system, it tricks the cell into rapidly making more copies of itself, each of which will carry the virus.
Why Do Some Infections Persist?
In preparing for the possibility of an antibiotic onslaught, some bacterial cultures adopt an all-for-one/one-for-all strategy that would make a socialist proud, University of Vermont researchers have found.
ASCB: A CELLebration of Cell Biology
The last major congress of the year, ASCB is less a platform for launching new products, but one for confirming and consolidating the trends that have emerged over the past 12 months.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!