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Common Cell Transformed into Master Heart Cell
By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin—Madison have generated master heart cells — primitive progenitors that form the developing heart.
Mitochondria Shown to Trigger Cell Ageing
An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.
Cancer Cells Kill Off Healthy Neighbours
Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.
Editing of Embryos Approved in the UK
The Human Fertilisation and Embryology Authority (HFEA) has approved a research application from the Francis Crick Institute to use new "gene editing" techniques on human embryos.
Microbes Take Their Vitamins
Scientists exploit organisms' needs in order to track 'vitamin mimics' in bacteria.
Machine Learning Uncovers Unknown Bacterial Features
Technique robustly identified characteristic gene expression patterns in response to antibiotics, low oxygen conditions.
CRISPR-Cas9 Gene Editing Advances Again
UC Berkeley researchers have made a major improvement in CRISPR-Cas9 technology that achieves an unprecedented success rate of 60 percent when replacing a short stretch of DNA with another.
Disrupting Cell’s Supply Chain Freezes Cancer Virus
When the cancer-causing Epstein-Barr virus moves into a B-cell of the human immune system, it tricks the cell into rapidly making more copies of itself, each of which will carry the virus.
Why Do Some Infections Persist?
In preparing for the possibility of an antibiotic onslaught, some bacterial cultures adopt an all-for-one/one-for-all strategy that would make a socialist proud, University of Vermont researchers have found.
ASCB: A CELLebration of Cell Biology
The last major congress of the year, ASCB is less a platform for launching new products, but one for confirming and consolidating the trends that have emerged over the past 12 months.
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Advantages of Moving Towards 3-D Scaffolds for Cell Culture
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Nanofiber Solutions

As a biologist, little thought is given to the materials which make up the products that we use in our research day-in and day-out. However, it is these materials which form the ‘building block’ or‘scaffold’ of all cell culture research. The intricate detail going into understanding the cellular response is all dependent on the topographical patterns and surface chemistry of the scaffold used to grow these precious cells. Countless studies have shown the importance of choosing the appropriate tissue culture scaffolds: one that mimics the nanofibrous nature of the extracellular matrix for a wide variety of applications including basic cell biology, drug discovery,tissue engineering, cell migration and invasion, and stem cell expansion and differentiation. Cell culture is mainly performed on tissue culture polystyrene (TCPS) multiwell plates as it is cheap,optically clear, and many cells grow well on it. In reality, however, living organisms are made up of an extracellular matrix that presents both aligned physical structure and support to the cells.

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