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Novel Tumor Treatment
In the first published results from a $386,000 National Cancer Institute grant awarded earlier this year, a paper by Scott Verbridge and Rafael Davalos has been published.
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Cancer-Fighting Tomato Component Traced
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Novel Stem Cell Line Avoids Risk of Introducing Transplanted Tumors
Progenitor cells might eventually be used to repair or rebuild damaged or destroyed organs.
Tissue Engineers Recruit Cells to Make Their Own Strong Matrix
Extracellular matrix is the material that gives tissues their strength and stretch. It’s been hard to make well in the lab, but a Brown University team reports new success. The key was creating a culture environment that guided cells to make ECM themselves.
Towards Patient-Specific Drug Screening
A new breakthrough by the 3D stem cell printing team at Heriot-Watt could pave the way to individually tailored drug testing regimes, both reducing the need for animal testing and ensuring that patients receive drugs which are most effective for their individual needs.
Artificial Kidney Research Gets A Boost
Development of a surgically implantable, artificial kidney — a promising alternative to kidney transplantation or dialysis for people with end-stage kidney disease — has received a $6 million boost.
Improving the Efficiency of Red Blood Cell Production
Study points to way of significantly reducing cost of laboratory-produced cells.
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Effective Heat Sterilization in CO2 Incubators
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Thermo Electron Corporation

Contamination control and elimination have beena major concern in cell culture laboratories for over100 years. Though other technologies have beendeveloped over this period for instruments, devices,and textiles, dry heat sterilization has emerged asthe most useful contamination eliminationtechnology for equipment chamber surfaces. A dryheat sterilization cycle has now been validated forThermo Electron Corporation's Steri-Cycle® CO2Incubators. This sterilization cycle readily eliminatesthe vegetative microorganisms, as well as persistentfungal spores, of concern in cell culture laboratories.Cycle time is based on validation procedures usingcommercially available spore suspensions calibratedfor dry heat resistance. The spores were inoculatedonto chamber wall, door, and gasket materials.The inoculated materials were exposed at theminimum temperature (the coolest, and therefore leastlethal) observed in the incubator as determined byextensive mapping studies.The validated cycle time was based on the longestaverage time required to achieve a six-log reduction ofthe most resistant spore batch tested. This exposuretime was then more than doubled to establish asterilization cycle that exceeds the requirements formedical instruments.

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