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Thursday, May 17, 2012
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Webcasts
UHPLC – Raising the Pressure in the LaboratoryUHPLC – Raising the Pressure in the Laboratory
Tony Edge, Thermofisher Scientific, speaking at Advances in Separation Technology 2011.
Micro Separation LC-MS Methods for Improving Retrospective Detection of Drug Administration for Evidential PurposesMicro Separation LC-MS Methods for Improving Retrospective Detection of Drug Administration for Evidential Purposes
Mark Parkin, King's College London, speaking at Advances in Separation Technology 2011.

Market Reports
Life Science and Chemical Instrumentation Market (2011 - 2016)
MarketsandMarkets

Spectroscopy, Chromatography, DNA Sequencer & Amplifier, Lab Automation, Array, Flow Cytometer, Electrophoresis, Immuno Assay & Others
Biomarkers
RI Technologies

This market insight report on Biomarkers focuses on the different types of biomarkers and their impact on various disease areas such as oncology, neurology, cardiology and other areas including metabolomic turmoil, arthritis, gynecology, oxidative stress, liver disease, pulmonary disease and aging.
Chiral Chemicals
RI Technologies

This market insight report on Chiral Chemicals focuses on the different Methods and Applications of Chiral Chemicals and their impact.
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Scientific News
Using a Spike-in Experiment to Evaluate Analysis of LC-MS Data
Data from the spike-in experiment can be used for developing and optimizing LC-MS data preprocessing algorithms and to evaluate workflows implemented in existing software tools.
LC-Tandem MS Analysis of Perfluorooctane Sulfonate and Perfluorooctanoic Acid in Fish Fillets
The methodology, developed by researchers from Mario Negri Institute, can be used to monitor and assess human exposure to perfluorinated compounds through sea food consumption.
On-line Concentration and Fluorescence Determination HPLC for PAHs in Seawater Samples and its Application to Japan Sea
This method, developed by researchers at Kanazawa University, allowed measurements in the low ng/g range, with high recoveries and a good intraday and interday repeatability.
Development of a Screening Method for the Determination of PCBs in Water
This novel method utilises gas chromatography coupled to triple quadrupole mass spectrometry for the simultaneous analysis of 11 polychlorinated biphenyls.
Thermo Scientific Launches European Seminar Series: “New Frontiers in Water Analysis”
Seminars will feature new Thermo Scientific water analysis products and solutions.
Esophageal Cancer Metabolite Biomarkers Detected by LC-MS and NMR Methods
Metabolic profiles derived from the combination of LC-MS and NMR methods were shown to readily distinguish EAC patients and potentially promise important routes to understanding the carcinogenesis and detecting the cancer.
Analysis of Host-Cell Proteins in Biotherapeutic Proteins by Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry
This paper presents assays for identification and quantification of host-cell proteins in biotherapeutic proteins over 5 orders of magnitude in concentration.
Quantitative Trace Analysis of a Broad Range of Antiviral Drugs in Poultry Muscle
Researchers from RIKILT-Institute of Food Safety report an LC-tandem mass spectrometry for the analysis of seven antiviral drugs in poultry muscle.
Discovery of Early-Stage Biomarkers for Diabetic Kidney Disease using MS-Based Metabolomics
This study demonstrates the potential of multivariate data analysis and metabolomics in the field of diabetic complications.
Workshops on Biofuels Analysis and New Applications for UHPLC
Phenomenex Inc. will be presenting two workshops at Pittcon 2012 in Orlando.
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Business News
European Life Science Awards Nominees Announced
The awards ceremony celebrates the very best of the industry’s achievements and precedes the Second European Lab Automation (ELA) conference and exhibition taking place from 30th- 31st May at the Congress Centre Hamburg.
Siemens Awarded Process Gas Chromatography Agreement by Shell
The agreement will see Siemens Industry Automation Division deliver process gas chromatographs to Shell For five years.
IBO Releases 2012 Instrument Industry Forecast
Instrument industry to grow 5.5% in 2012.
PerkinElmer and TPM Biotech SDN. BHD. Partner to Validate Screening Application for Halal Food Products
Companies collaborate to explore potential applications of PerkinElmer’s Porcine Detection Kits and chromatography solutions for use in validating methods of testing food products for compliance with Halal certification regulations.
Agilent and Universiti Putra Malaysia to Collaborate on Halal Food Research
Agilent will provide HPRI with the Agilent 6490 triple quadrupole LC/MS system.
Pittcon 2012 Releases Conference Summary
The Pittcon 2012 Organizing Committee announced that this year's conference and exposition for laboratory science attracted 15,754 attendees (conferees and exhibitor personnel) to the annual event.
Novasep Opens New Shanghai Facilities
New site increases Novasep’s process development and engineering capabilities to supply turnkey purification processes in East Asia.
Malvern Instruments Opens New Multipurpose Facility in Houston
At 22,000 sq. ft. the new building is double the size of Malvern’s previous premises in Houston and houses state-of-the-art laboratories, product development, manufacturing and commercial operations.
Partisil & Partisphere HPLC Column Range Acquired by Hichrom
Hichrom acquire Partisil & Partisphere HPLC column range from Whatman.
Professor from Milan Awarded Inaugural Arnold O. Beckman Medal for Electrodriven Separations
Pier Giorgio Righetti honored at MicroScale Bioseparations conference.
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Events
Company Logo - 36th International Symposium o
27 May 2012
36th International Symposium o ...
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Company Logo - HPLC 2012: 38th Symposium on H
16 Jun 2012
HPLC 2012: 38th Symposium on H ...
More information
Company Logo - ACHEMA 2012 - International Ex
18 Jun 2012
ACHEMA 2012 - International Ex ...
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Company Logo - Separation Science 2012
27 Jun 2012
Separation Science 2012 ...
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ePosters
Ion Chromatography ICP-Q-MS for the Detection of Arsenic Species in Apple Juice
Thermo Scientific

Interest in the determination of Arsenic species in fruit juices has been triggered by recent media reports in the United States claiming that some apple juices may contain high amounts of Arsenic. Inorganic forms of Arsenic (As3+ and As5+) are highly toxic, whereas the organic forms (e.g. arsenobetaine) are not considered toxic. A robust IC-ICP-MS system was developed and shown to be a highly selective and sensitive technique for determination of trace element species.
Streamlined QbD HPLC Method Development with Automated Data Processing
ACD/Labs

Quality by Design (QbD) has been widely applied to pharmaceutical manufacturing to enhance process robustness, and improve product quality and manufacturing productivity. Recently, there arose tremendous interests from both the pharmaceutical industry and regulatory agents to expand it to analytical methodology.
Characterizing Small Molecules in Biological Extracts using IntelliXtract Data Processing on High Resolution Accurate Mass Time-of-Flight Data
ACD Labs

To detect small molecules in biological extracts, LC/MS performed using high resolution time of flight with accurate mass analysis is a powerful technology. Together with advanced data processing algorithms, accurate mass and relative isotope abundance measurements, molecular formulae can be determined and compounds identified.
The LAB2LAB™Advantage
1Novartis 2TTPLabtech Ltd

Lab2Lab is a novel approach to submitting and transporting samples for analysis across an entire site. Sample tubes are registered and methods selected, an ELN reference is assigned and the sample tube is placed into the “Sender”. The system transports the samples using low pressure compressed air and directs them to the most appropriate analytical instrumentation available. The analytical results are then automatically returned to the originators ELN.
Qualitative Comparison of Wine Process Samples with UHPLC and Ultra-High Resolution TOFMS
Leco Corporation

The evaluation, identification, and quantitation of flavones, antioxidants and related nutrients, biogenic amines, and potential contaminants in wine and other foodstuffs provides valuable information on their nutritional and health values.
Analysis of Pesticide Residues in JonaGold Apples Using QuEChERS Approach and Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry (GCxGC-TOFMS)
LECO Corporation

Screening and quantitation of pesticide residues in fruits and vegetables is of utmost importance for public health and safety concerns. These commodities can contain hundreds-to-thousands of analytes, making them extremely difficult for the screening and accurate quantitation of pesticide residues.
Analysis of Fruit Commodities by GC-TOFMS and GCxGC-TOFMS Using QuEChERS Approach
LECO Corporation

The availability of fruit commodities from a wide variety of sources has increased the need for rapid and accurate screening for pesticides in fruit. Not all fruit commodities are brought to market under the strict guidelines of the United States Department of Agriculture. Determining whether or not the Environmental Protection Agency tolerances for various pesticides have been violated is important in the risk assessment for consumers in the United States.
Characterization of Nutrients and Actives in Herbal Supplements and Nutriceuticals Using UHPLC-Multi-Reflecting Time-of-Flight Mass Spectrometry
LECO Corporation

The qualitative and quantitative analysis of the content of nutritional supplements and alternative medicinal therapies is becoming more important and regulation by the FDA is imminent. High resolution mass spectrometry provides a rapid, selective, and useful mechanism for QC of extracts and finished dosage forms, producing a minable, comprehensive data set.
Facing the challenges in bio-pharmaceutical production: newly developed polymer-based ion exchange chromatography media and their application to the purification for Immunoglobulin – from egg yolk
YMC

Much attention has been given to ion exchange (IEX) media as a means to improve productivity as a result of increasing demand for higher efficiency on the downstream process. Until recently, strain optimisation for high productivity and upstream purification were the bottlenecks for most bio-processes.
Detection of Environmental Contaminants Caused by the Oil Spill in the Gulf of Mexico by GC and HPLC
Phenomenex

In order to help understand the impact that the oil spill has caused, laboratories are looking for rapid and robust analytical procedures to characterize the hydrocarbon contaminants. This work provides SPE, GPC, GC-FID, GC/MS, and HPLC analytical methods for analyzing the most common contaminants that originated from the leak.
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Application Notes
Analysis of Fat-Soluble Vitamins from Food Matrix for Nutrition Labeling
Agilent Technologies

Labelling vitamins in a matrix like infant formula is a mandatory requirement by the FDA. The diversity in the chemical nature of vitamins makes concurrent extraction and analysis of all vitamins challenging. Due to this, analysis of water soluble and fat soluble vitamins will be usually performed separately. This Application Note describes a sen¬sitive and robust method for simulta¬neous determination of nine fat soluble vitamins with UV detection.
Analysis of Natural and Artificial Vanilla Preparations
Agilent Technologies

Vanilla extract is widely used as a flavoring ingredient in foods and beverages. It contains approximately 200 substances. Since natural vanilla extract is limited and prices are high, artificial vanilla flavorings are often used. Due to quality and price concerns, it is important to differentiate between these two.
Analysis of Ascorbic Acid, Citric Acid and Benzoic Acid in Orange Juice
Agilent Technologies

While some fruit naturally contain ascorbic acid, citric acid and benzoic acid, these components are added additionally added to fruit juices to increase the shelf life. Although the regulatory limit for benzoic acid in fruit juices is 400 to 600 µg/mL, concerns exist regarding the liberation of carci¬nogenic benzene by reaction of benzoic acid with ascorbic acid under certain conditions.
Determining Total Sugar Content in Maple Syrup to Meet FDA Nutrition Labeling Requirements
Agilent Technologies

Nutrition labels on food items provide valuable information to consumers. To ensure authenticity, the Food and Drug Administration checks the reported values on the nutrition labels. Due to advances in chromatography and universal analysis of sugars by refractive index detectors (RI), RI is the preferred method for sugar analysis. A total sugar analysis method for commercially available maple syrup was performed using Agilent HiPlex Ca Column and Agilent 1260 Infinity RI Detector.
Analysis of Acharicides in Honey
Agilent Technologies

To prevent economic losses beekeepers treat their colonies with acaricides. The use of these acaricides inside beehives implies a risk of direct pollution of honey and other hive products, therefore maximum residue levels on honey have been fixed in many countries to protect consumers.
Two-Dimensional HPLC Combined with On-Line SPE for Determination of Sudan Dyes I–IV in Chili Oil
Dionex - Part of Thermo Fisher Scientific

Although use of Sudan dyes in food is restricted, they are nevertheless sometimes added to foods to improve the appearance and command a higher price. Because Sudan dyes may create health problems such as genotoxic and carcinogenic effects, concerns over contamination of Sudan dyes has increased awareness and testing for these compounds.
Fast Determination of Anthocyanins in Pomegranate Juice
Thermo - Part

Due to their strong antioxidant properties, anthocyanins are of considerable interest. Pomegranate juice (PJ) has been reported to contain 3× more antioxidant activity than green tea. Due to the high demand for pomegranates, adulteration of PJ has become widespread. Manufacturers have attempted to extend the limited supply by blending with filler ingredients such as cane sugar, corn syrup sweeteners, and lower-quality juices containing sorbitol, malic acid, and sucrose.
Analysis of Fruit Juice Adulterated with Medium Invert Sugar from Beets
Dionex - Part of Thermo Fisher Scientific

Fruit juice adulteration presents an economic and regulatory problem. The United States orange juice industry estimates that orange juice sales gross more than one billion dollars annually. The most common forms of adulteration include simple dilution and blending of inexpensive and synthetically produced juices into the more expensive ones.
Potassium Bromate in Bakery Products
Cecil Instruments Ltd

Potassium bromate is recognised as one of the best dough conditioners in the bakery industry. Scientific evidence surfaced in 1990, implicating bromate as a possible carcinogen. In response the United Nations Joint Food and Agricultural Organisation and the WHO reduced bromate residuals to less than 5 parts per billion (ppb) in finished products.
Simultaneous Analysis of Anions and Cations by Tandem Chromatography with Conductivity Detection
Cecil Instruments Ltd

Tandem chromatography is emerging as a powerful technique to double the output of HPLC equipment by simultaneously carrying out two different analyses on the same sample. The principle is straightforward: the sample is split in two at the injection port, and each aliquot is eluted on a different column and analysed by a different detector.
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