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Detection of Emerging Contaminants in Wa...
 An Illustrated History of Gas Chromatog...Behind the Science, ep. 12: My Samples A...Behind the Science, ep. 13: SPE vs. matr...

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Do it with our UNcle... we mean protein characterizationDo it with our UNcle... we mean protein characterization
In this webinar we will demonstrate our streamlined software package, allowing you to quickly and easily assess your protein stability.
The Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in DiseaseThe Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in Disease
Join us to learn about the key challenges in lipid analysis and how the Lipidyzer platform can help you overcome them.

Market Reports
Label-Free Binding Analysis Trends 2014

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Scientific News
Food Analysis Applications of Core-Shell Columns in HPLC
Despite applications of core-shell particles columns in food analysis being at an early stage, articles describing their use for improving separations of several classes of compounds are becoming more frequent.
New Pathway for COPD Biomarker Development
A study from Philip Morris International has highlighted multi-lipid profiling as a potential new pathway for COPD biomarker development.
Reclaim from the Drain - The Importance of Water Reuse
This infographic explains the importance of reusing water to meet the world's increasing water demand.
Curcumin Shows Promise as Cancer Treatment
When delivered at the correct circadian phase, curcumin demonstrates sustained toxicity in cancer cells and should be considered for use in patient care.
Clinical Trial Finds Medicine Program Alters Blood Serum
Meditation, yoga and vegetarian diet linked to decline in plasma metabolites associated with inflammation and cardiovascular disease risk.
3D-Printing in Science: Conference Co-Staged with LABVOLUTION
LABVOLUTION 2017 will have an added highlight of a simultaneous conference, "3D-Printing in Science".
Antibiotic Resistance Can Occur Naturally in Soil Bacteria
Scientists have found natural anti-biotic resistant bacteria in soils with little to no human exposure.
Impact of Emerging Contaminants in Our Water Supply
Emerging contaminants, any synthetic or naturally occurring chemical not commonly monitored in the environment, in our water supply are becoming of increasing concern due to their potential ecological and/or human health effects.
Collaboration to Develop Cannabis Testing Standards
SCIEX workflow solution enables cannabis labs to ensure product safety with robust, cost-effective analytical methods to facilitate routine testing.
Antibiotic Resistance Genes in Indoor Dust
Genetic analyisis of dust samples discovered antimicrobial chemicals and antibiotic-resistance genes.
Business News
smartLAB 2017: For Tomorrow’s Intelligent Laboratories
smartLAB 2017 will be held 16-18 May at LABVOLUTION along side BIOTECHNICA life sciences show.
Danaher to Acquire Phenomenex
Company will operate as a standalone operating company, retaining the Phenomenex brand, its personnel and site locations.
Ellutia Agrees New Strategic Alliance with Prism Analytical
The alliance calls for innovative solutions in chromatography technology.
Purolite, CPI Collaborate
Collaboration aims to evaluate its Praesto® modern high flow agarose Protein A resins.
Pittcon Announces 40+ New Classes in 2017 Short Course Program
The courses for broad-based application and general lab functions include lab management, quality control, technical writing, statistics, data management, and lab safety.
Tecan to Acquire SPEware Corporation
Tecan Group has announced the acquisition of SPEware Corpaoration with a base cash purchase of $50 million.
IBO Announces Industrial Design Award Winners
IBO announced their Industrial Design Awards winners in three separate award categories.
Overcoming the Challenges of KF Analysis
Metrohm USA is pleased to announce a series of seminars dedicated to Karl Fischer (KF) analysis hosted in 16 cities across the US and Canada.
InSource Launches Clinical Trial Focused on PGx
Physicians' offices invited to become research sites and enroll patients.
SCIEX Works with the Francis Crick Institute and the University of Cambridge
New proteomic study to develop advanced resource for precision medicine research by using Microflow SWATH® Acquisition for HT industrialized proteomics.

Do it with our UNcle... we mea
26 Oct 2016
Do it with our UNcle... we mea ...
More information
WWEM - Water, Wastewater & Env
02 Nov 2016
WWEM - Water, Wastewater & Env ...
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Lab Innovations 2016
02 Nov 2016
Lab Innovations 2016 ...
More information
EMBO Conference: Molecular Mac
20 Nov 2016
EMBO Conference: Molecular Mac ...
More information

A Novel Benchtop Time-of-Flight GC-MS System for High Performance Analysis of Human Urine
LECO Corporation

A workflow was developed and implemented for the effective comparison of urine. It involved the preparation of stable compounds through derivatization, data acquisition using a high performance benchtop TOFMS, comprehensive data processing (NonTarget Deconvolution™), and quick retrospective analysis of rich datasets using Target Analyte Finding.

Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
Accurate Mass Spectral Database: Harnessing the Power of High Performance Mass Spectrometry at Long Last
LECO Corporation, Moscow State University

Standard mixtures comprising of alkanes, PAHs, semivolatiles, and pesticides were analyzed using a high resolution time-of-flight (HRTOF) mass spectrometer—Pegasus GC-HRT (LECO Corporation, Saint Joseph,MI)—at 10 spectra-per-second (m/z40–300) in high resolution mode (25,000 at FWHH). The resulting chromatographic peaks were automatically found, deconvoluted, and curated into an Accurate Mass Library (AML).
Automated Sample Preparation of Whole Blood for Therapeutic Drug Monitoring and Diagnostics by LC-MS using a Commercial Autosampler
1 University of Applied Sciences and Arts Northwestern Switzerland FHNW, Institute for Chemistry and Bioanalytics , Gründenstrasse 40, 4132 Muttenz; 2 CTC Analytics AG; Industriestrasse 20, CH-4222 Zw

In this poster the parameters necessary to automatically prepare whole blood samples for online LC-MS applications in the field of diagnostics and TDM have been investigated. A strategy and the most important parameters are shown for the optimization of a PAL RTC autosampler
for the preparation of whole blood samples.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Analysis of Terpenes Using Gas Chromatography with Vacuum Ultraviolet
The University of Texas at Arlington and VUV Analytics

The VUV absorption spectra for different terpenes were distinctive and differentiable. GC-VUV demonstrated the capabilities for qualitative and quantitative analysis of terpenes in turpertine mixtures. Chromatographic coeluting signals can be deconvolved by the VUV data analysis software.

Determination of C2-C12 Aldehydes in Water by SPME Arrow On-Fiber Derivatization and GC/MS
1 BGB Analytik AG, Lettenstrasse 97, 8134 Adliswil, Switzerland; 2 CTC Analytics AG, Industriestrasse 20, 4222 Zwingen, Switzerland

A method applying SPME Arrow extraction and on-fiber derivatization for the quantitation of C2-C12 aldehydes in water by GC/MS is described.
Assessing Diversity in Cassava through the Application of Metabolomics
aSchool of Biological Sciences, Royal Holloway University of London, Egham, UK bInternational Center for Tropical Agriculture, CIAT

In the present study metabolomic platforms have been established for Cassava and used to assess the biodiversity present in Cassava germplasm collections and elucidate underlying biochemical mechanisms associated with traits of interest.
PredRet: Prediction of Retention Time by Direct Mapping between Multiple Chromatographic Systems
Department of Food Quality and Nutrition, Research and Innovation Centre, Fondazione Edmund Mach, San Michele all’Adige (TN), Italy.; Department of Stress and Developmental Biology, Leibniz Institute

Retention time (RT) information is under-utilized in LC-MS based metabolomics and sharing of RTs between systems is not currently possible. PredRet is a new system that allows highly accurate mapping and prediction of RTs between LC systems.
Minimizing Carry-over for High Throughput Analysis
1FHNW Fachhochschule Nordwestschweiz, Hochschule für Life Sciences Gründenstrasse 40 CH-4132 Muttenz; 2CTC Analytics AG Industriestrasse 20 CH-4222 Zwingen; Switzerland

Minimal carry-over is a prerequisite for high throughput analysis. However, minimized carry-over and cycle time are competing and a careful optimization is mandatory. In this study the influence of wash conditions on carry-over of various compounds was investigated. A strategy to minimize carry-over was developed. The influences of different wash tasks were investigated. Finally the contribution of different system components such as injector valve or column was studied.
Application Notes
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research

The Lipidyzer™ Platform, powered by Metabolon®.
Novel Chemical Standards Kits Enable Facile Lipid Quantitation

The Lipidyzer platform provides more accurate lipid analysis with less quantitative bias.
Characterization of Protein-Protein Interactions using Triple Detection Size Exclusion Chromatography (SEC-TD)
Malvern Instruments Limited

In this application note, triple detection size exclusion chromatography (SEC-TD) is used to understand the ability of proteins to form ordered, structured complexes. The controlling mechanism behind these protein complexes is fundamental to our knowledge of protein signaling pathways and the physiological responses they control.
Characterization of IgG Monomers & Their Aggregates
Malvern Instruments Limited

A comparison between column calibration & multi-detection SEC.
Differentiation of Polymer Branching and Composition Using the Mark–Houwink Plot
Malvern Instruments Limited

In this application note, we will show, using polystyrene, how to separate the effects of a structural difference induced by a compositional change (bromination) and the structural change induced by polymer chain branching using the Mark- Houwink plot.
Automated Sample Preparation - Analysis of 25-OH-Vitamin D3 and 25-OH-Vitamin D2 by LC/MS/MS
Beckman Coulter Life Sciences

Automated Sample Preparation for the Monitoring of Pharmaceutical and Illicit Drugs by LC-MS/MS
Beckman Coulter Life Sciences

Automated Sample Preparation for the Monitoring of Ethanol Metabolites in Urine by LC-MS/MS
Beckman Coulter Life Sciences

Automating Protein Digestion for Reproducible Proteomics
Beckman Coulter Life Sciences

Use Of Microcalorimetry And Its Correlation With Size Exclusion Chromatography For Rapid Screening Of The Physical Stability Of Large Pharmaceutical Proteins In Solution
Malvern Instruments Limited


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