Corporate Banner
Satellite Banner
Technology Networks Header
Saturday, April 19, 2014
Technology Networks
 
Register | Sign in
LabTube Meets Trish Meek, Thermo Scienti...
Principles of Affinity chromatography...LabTube Meets Dr Rohit Khanna, Waters...SELECTBIO Online Events...

Featured Products
Featured Product - AcroSep™ 1 mL Pre-Packed Chromatography ColumnsAcroSep™ 1 mL Pre-Packed Chromatography Columns
AcroSep™ 1 mL Pre-Packed Chromatography Columns
Featured Product - Restek Electronic Leak DetectorRestek Electronic Leak Detector
Restek Electronic Leak Detector

Webcasts
Streamlining Routine Chromatography Analyses using eWorkflows Streamlining Routine Chromatography Analyses using eWorkflows
Darren Barrington-Light, Product Specialist, Thermo Scientific
Towards an Exosomes-based Molecular Test for Remission Monitoring of CancerTowards an Exosomes-based Molecular Test for Remission Monitoring of Cancer
Michiel Pegtel, VU University Medical Center, speaking at Molecular Medicine Congress 2013.

Market Reports
Biomarkers
RI Technologies

This report on focuses on the different types of biomarkers and their impact on various disease areas. The study also provides global market analysis for biomarkers by disease area and by prominent biomarker identification technologies.
Life Science Consumables 2013: Markets and Opportunities
Biopharm Reports

Techniques such as PCR, DNA microarray, DNA sequencing, mass spectrometry and flow cytometry have grown significantly in the last decade and by 2015 markets for these five areas are expected to exceed $50 billion, globally. In these and related fields, consumables are generally the second or third largest area in cost terms, after instrumentation.
Mass Spectrometry 2013: A Focus on Sales Growth
Biopharm Reports

Mass Spectrometry 2013 presents the findings of a global market study of mass spectrometry, involving the participation of 567 buyers and end-users in this field. With a focus on market development, sales growth and commercial opportunities, the study profiled current and evolving areas of this market, as outlined below. Its findings provide valuable product and market information, and decision-making support to suppliers in the mass spectrometry field.
Mass-Spec Based Screening Assay Trends 2013
HTStec

This market report summarizes the results of HTStec's 1st industry-wide global web-based benchmarking survey on mass spectrometry (MS)-based screening assays carried out in February 2013.
Lab Instrument Rental Trends 2012
HTStec

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on lab instrument rental carried out in September 2012.
Scientific News
Elucidating Odor Properties of Elk River Contaminants
Virginia Tech researchers utilized olfactory gas chromatography to pinpoint the concentrations of contaminants in the air.
Thousand Times Sensitivity Increase for Doping Drugs Testing
Method developed by UT Arlington researchers can be up to 1,000 times more sensitive than many current tests.
Development and Validation of LC/MS/MS Method and its Application to a Pharmacokinetic Study
Researchers aimed to develop a LC/MS/MS method to monitor plasma levels of montelukast, gliclazide, and nifedipine for application in pharmacokinetic studies and routine clinical practice.
Monitoring and Risk Assessment of Pesticide Residues in Commercially Dried Vegetables
The study aimed to analyze the presence of 253 pesticides commonly used on dried vegetables and to check their compliance with existing regulations.
Evaluation of Thermally Degraded Vegetable Oils using FTIR and GCMS
Researchers report a synchronised signal processing algorithm that caters both FTIR and GCMS signal for evaluation of thermally degraded vegetable oils.
Determining Chromium(VI) in Toys
Metrohm has developed an ion chromatography method using pre-concentration and Inline Matrix Elimination.
Substances in Hop Leaves Could Fight Dental Diseases
A novel sequential chromatographic technique was applied to the comprehensive separation of polyphenols and related compounds from a hop bract extract.
New Support for HPLC Based on Silica Coated with Alumina Particles
Paper also presents the viability of using the material as a chromatographic support for RPLC.
Halal Meat Authenticity Testing Reassures Consumers of No Pig or Horse Contamination
New LC/MS/MS-based meat speciation method allows food testing laboratories to detect pig and horse contamination in diverse food products, with higher accuracy than existing methods.
Metabolomics Reveals a Role for the Chromatin-Binding Protein HMGN5 in Glutathione Metabolism
This study links the expression of HMGN5 to transcriptional changes that affect glutathione metabolism in the liver.
Business News
Canada Invests $30.4M in University Research Infrastructure
The funding at 32 universities was announced by Ed Holder, Minister of State (Science and Technology).
Pittcon Announces Recipients of the Editors’ Awards
Recipients include Texas Instruments (Gold), Waters (Silver) and ABSciex (Bronze).
Shimadzu Registers HPLC and LCMS Instruments as Class I Medical Devices with FDA
Products are the first Shimadzu analytical instruments registered with the FDA as medical devices.
Novasep Reports Full Year 2013 Results
Results show strong growth and beating guidance.
Industry-Sponsored Academic Inventions Spur Increased Innovation
Analysis questions assumption that corporate support skews science toward inventions that are less useful than those funded by the government or non-profit organizations.
Thermo, Harvard Establish Center for Multiplexed Proteomics
Thermo Fisher Scientific Center for Multiplexed Proteomics at Harvard Medical School aims to expedite understanding of complex disease mechanisms.
Agilent Supports NUS-Led Research Consortium to Identify, Map Lipid Levels in Healthy People
New international effort to develop world's first integrated systems biology database for different races and ethnicities.
EquipNet to Discuss Asset Management Systems at Interphex 2014
Visit EquipNet on Booth #1239.
Waters ACQUITY QDa Detector Takes Pittcon Editors' Award
Product receives Editors' Silver award for the most innovative product introduced at Pittcon 2014.
Agilent, University of Arizona to Host Environmental Analysis Techniques Workshop
Dr. Shane Snyder, EPA Scientists, Leading Environmental Labs to Present Data on Recycled Water, Hydraulic Fracturing, Trace Contaminants in Water.

Events
CMC Strategy Forum Europe 2014
05 May 2014
CMC Strategy Forum Europe 2014 ...
More information
HPLC 2014
11 May 2014
HPLC 2014 ...
More information
38th ISCC and 11th GCxGC Sympo
18 May 2014
38th ISCC and 11th GCxGC Sympo ...
More information
62nd ASMS Conference on Mass S
15 Jun 2014
62nd ASMS Conference on Mass S ...
More information

ePosters
GC-MS Comparison of Lavindin Grosso Oil Obtained by Steam Distillation and SFE
Miami University Middletown

Oil was extracted from Lavindin Grosso using steam distillation and using supercritical fluid extraction (SFE). Multiple analyses of the same extract demonstrated repeatability of the analytical method. The variability between batches of distillate bracketed the composition obtained by SFE. The differences among the oils could be attributed more to where the lavender was grown than to the extraction method.
Identification and classification of antifouling compounds secreted by anti MIC microorganisms. A metabolomic analysis.
University of Burgos, INBIOTEC, CSIC and ACCIONA Infraestructuras, Spain

BIOCORIN project, aims to develop a green alternative to the coatings and solutions used up to date for MIC corrosion control. Some of the results of this project are presented here, with the identification of several relevant antifouling compounds secreted by environmentally isolated anti-MIC strains of microorganisms via a metabolomic approach.
Trace Level Analysis of Perchlorate and Bromate in Various Water Matrices using Suppressed Ion Chromatography
Metrohm USA

Bromate and Perchlorate are ubiquitous analytes in various water matrices and analysis in trace level is a challenge
Investigation of Chemical Contaminants in Soils Following Superstorm Sandy
*Marist College Department of Chemistry, Biochemistry and Physics, Poughkeepsie, NY. †Vassar College Chemistry Department, Poughkeepsie, NY

Investigation of Chemical Contaminants in Soils Following Superstorm Sandy
Determination of Metabolically Unstable Drugs in Blood by Heat-Stabilized DBS and LC-MS/MS
Denator AB

The aims of this work were to investigate drug stability prior to, during and after blood spot sampling, using procaine, prulofloxacine, esmolol, and acetylsalisylic acid as examples of drug compounds with limited stability and to compare conventional DBS sampling procedure with DBS sampling including heat stabilization.
Determination of Metabolically Unstable Drugs in Blood by Heat-Stabilized DBS and LC-MS/MS
Denator AB

The aims of this work were to investigate drug stability prior to, during and after blood spot sampling, using procaine, prulofloxacine, esmolol, and acetylsalisylic acid as examples of drug compounds with limited stability and to compare conventional DBS sampling procedure with DBS sampling including heat stabilization.
Ion Chromatography ICP-Q-MS for the Detection of Arsenic Species in Apple Juice
Thermo Scientific

Interest in the determination of Arsenic species in fruit juices has been triggered by recent media reports in the United States claiming that some apple juices may contain high amounts of Arsenic. Inorganic forms of Arsenic (As3+ and As5+) are highly toxic, whereas the organic forms (e.g. arsenobetaine) are not considered toxic. A robust IC-ICP-MS system was developed and shown to be a highly selective and sensitive technique for determination of trace element species.
Streamlined QbD HPLC Method Development with Automated Data Processing
ACD/Labs

Quality by Design (QbD) has been widely applied to pharmaceutical manufacturing to enhance process robustness, and improve product quality and manufacturing productivity. Recently, there arose tremendous interests from both the pharmaceutical industry and regulatory agents to expand it to analytical methodology.
Characterizing Small Molecules in Biological Extracts using IntelliXtract Data Processing on High Resolution Accurate Mass Time-of-Flight Data
ACD Labs

To detect small molecules in biological extracts, LC/MS performed using high resolution time of flight with accurate mass analysis is a powerful technology. Together with advanced data processing algorithms, accurate mass and relative isotope abundance measurements, molecular formulae can be determined and compounds identified.
The LAB2LAB™Advantage
1Novartis 2TTPLabtech Ltd

Lab2Lab is a novel approach to submitting and transporting samples for analysis across an entire site. Sample tubes are registered and methods selected, an ELN reference is assigned and the sample tube is placed into the “Sender”. The system transports the samples using low pressure compressed air and directs them to the most appropriate analytical instrumentation available. The analytical results are then automatically returned to the originators ELN.
Application Notes
Tecan AC Extraction Plate™
Tecan Group Ltd.

A growing number of laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) for the determination of vitamin D. The advantage of the latter method is unparalleled specificity combined with high sensitivity, offering the potential for the determination of multiple analytes, such as 25OH-vitamin D3 and 25OH-vitamin D2.
Tecan AC Extraction Plate™
Tecan Group Ltd.

There is an increasing demand for the determination of Vitamin D status which is based on the quantification of the two metabolites 25-OH-Vitamin D3/D2. Numerous laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) because of its specificity combined with high sensitivity. Moreover LC-MS/MS offers the potential for multianalyte determination which is required for Vitamin D status determination.
Tecan AC Extraction Plate™
Tecan Group Ltd.

THC , the main active compound in marijuana, is metabolized to ?9-(11-OH)-tetrahydrocannabinol (11-OH-THC) and 11-nor-?9-carboxy-tetrahydrocannabinol (THC-COOH). Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Tecan AC Extraction Plate™
Tecan Group Ltd.

Testosterone is a powerful androgen that is primarily secreted by Leydig cells in men and theca cells in women. For accurate, reproducible quantification of testosterone, a growing number of laboratories is shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS). This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.
Protein Purification Workflow Development Using Bio-Rad's NCO' Chromatography System
Bio-Rad Laboratories

High purity protein is a common requirement for biochemical and structural studies. A common approach is to recombinantly express an affinity-tagged version of the protein of interest. This is, however, not always a viable option. This application note discusses protein purification workflow development for untagged proteins and introduce a new indicator of method performance, the purity quotient difference.
The Analysis of Common Drugs of Abuse in an Oral Fluid Matrix using a New Q TRAP® Platform
AB SCIEX

The multiplexing analysis of several compound classes, such as common prescription drugs along with drugs of abuse is very important. The measurement of these drugs has generally been performed using urine as the sample matrix. However, many research laboratories are finding the need to analyze these compounds in oral fluid matrices.
Quantification of Ethylglucuronide in hair by Liquid Chromatography Tandem Mass Spectrometry
AB SCIEX

An advantage of the use of ethylglucuronide (ETG) in hair is that it is not subject to the effect of bacteria. It also offers the opportunity to extend the window of detection up to 6 months compared to hours- days in blood and urine.
Can LC-MS/MS Be Used in Horse Meat Detection?
AB SCIEX

Following the Food Standards Agency’s announcement that horse and pig DNA had been identified in beef products sold by several supermarket chains, further testing has revealed widespread incidences of such contamination. This application note details a rapid, robust, sensitive and specific LC-MS/MS assay for the simultaneous detection of horse meat and the banned substance phenylbutazone (BUTE).
Advanced Automated Library Searching for Compound Identification in Forensic Toxicology Samples
AB SCIEX

LC-MS/MS utilization in forensic toxicology screening for drugs and drug metabolites has become increasingly popular due to the selectivity, sensitivity and the speed of LC-MS/MS analysis. MS/MS confirmation with automated searching against available spectral libraries has proven to add a superior level of confidence to the compound identification.
Tryptic Mapping Automated on the CyBi®-RoboSpense and Integration of an Agilent 1100/1200 HPLC System for Peptide Analysis
CyBio

This application note describes automation of the tryptic mapping process on the CyBi®-RoboSpense liquid handling platform. The automation is completed through integrating an Agilent 1100/1200 HPLC system.
Skyscraper Banner
Skyscraper Banner
Follow TechNetcom1 on Twitter
Technology Networks Ltd. on LinkedIn
Go to LabTube.tv