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Webcasts
The Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in DiseaseThe Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in Disease
Join us to learn about the key challenges in lipid analysis and how the Lipidyzer platform can help you overcome them.
How to Optimize Sample Preparation Step Prior to ExtractionHow to Optimize Sample Preparation Step Prior to Extraction
Discover the benefits of bead-binding for sample preparation in this on demand webinar from Bertin Technologies.

Market Reports
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Scientific News
Featured Article - ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.

Making Metabolite Identification More Efficient
Metasense combines the industry's most-comprehensive metabolic transformation prediction with efficient analysis of LC/MS analytical measurements to identify, visualize, and report chemical biotransformations.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Origins of Life Delivered from Space
Researchers have for the first time shown that ribose, a sugar that is one of the building blocks of genetic material in living organisms, may have formed in cometary ices.
Protecting Yourself from Mosquitoes Just Got Easier
New GoClip™ from RESCUE!® offers six days of protection from mosquitoes as well as biting flies and ticks.
Structure of Essential Digestive Enzyme Uncovered
Using a powerful combination of techniques from biophysics to mathematics, researchers have revealed new insights into the mechanism of a liver enzyme that is critical for human health.
Why do Tomatoes Smell "Grassy"?
Researchers identify enzymes that convert the grassy smell of tomatoes into a sweeter scent.
Plasma Biomarkers for Breast Cancer Diagnosis
Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions.
A Mechanistic Tool for Studying Fungal Pathogens
This study presents an overview of lipid extraction, chromatographic separation and mass spectrometry employed in qualitative and quantitative sphingolipidomics in fungi.
Newborn Screening Test Developed For Rare, Deadly Neurological Disorder
Scientists have developed a new dried blood spot screening test for Niemann-Pick type C, with goal to speed diagnosis and treatment.
Business News
SCIEX Works with the Francis Crick Institute and the University of Cambridge
New proteomic study to develop advanced resource for precision medicine research by using Microflow SWATH® Acquisition for HT industrialized proteomics.
Thermo, NIBRT Announce Collaboration
Analytical solutions designed to streamline workflows, quickly generate data for deeper understanding of molecular complexes.
Waters Collaborates with Singapore’s Bioprocessing Technology Institute
Organizations partner to enhance the development of analytical methods and glycan libraries for cancer glycobiology, focusing on glycosphingolipids.
£18m Lab Opens to Discover the Clues to Individuals’ Illnesses
The Centre will identify biomarkers – the molecular clues that indicate the presence of a disease or condition.
Biotage Achieves ISO 14001:2004 Certification
This certificate is an international standard for an environmental management system (EMS) that helps businesses such as Biotage control and improve practices that are potentially harmful to the environment.
IDT Acquires Oligonucleotide Synthesis Company ValueGene
Company welcomes new customers with promise to provide seamless support for genomics research.
LEAP Technologies, Antec Collaborate
LEAP Technologies and Antec announced their collaboration in the field of sample preparation for HDX/MS.
SGS to Offer HDX–MS at West Chester Facility
SGS has announced that it will expand its higher order structure analysis services for proteins at its West Chester, PA facility with an investment in Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) capabilities.
Grace to Focus on Pharma, Nutraceutical Business
W. R. Grace & Co. has affirmed its commitment to three growing service lines for the pharmaceutical and nutraceutical industries, and announced agreements to sell product lines associated with its chromatography instruments, columns, and related laboratory products.
Thermo Extends Collaboration with University of Birmingham
New Phenome Centre Birmingham, UK to use Thermo Scientific mass spectrometry instruments to advance metabolic phenotyping and metabolomics studies.

Events
The Lipidyzer™ Platform: A Rev
19 Jul 2016
The Lipidyzer™ Platform: A Rev ...
More information
CMC Strategy Forum: Drug Produ
18 Jul 2016
CMC Strategy Forum: Drug Produ ...
More information
Food & Beverage Analysis
19 Aug 2016
Food & Beverage Analysis ...
More information
4th International Conference a
29 Aug 2016
4th International Conference a ...
More information

ePosters
Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources
Biological Industries

An overview of a novel SF, XF differentiation system which enables achieving defined conditions for rapid generation of differentiated hMSCs towards tissue engineering and drug screening applications.
Molecular Abnormalities in Schizophrenia: Neurotransmission, Oxidative Stress, and Apoptosis
1Section of Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, London SW7 2AZ, U.K. 2

A multi-platform approach was employed to analyse distinct brain regions implicated in schizophrenia.
Accurate Mass Spectral Database: Harnessing the Power of High Performance Mass Spectrometry at Long Last
LECO Corporation, Moscow State University

Standard mixtures comprising of alkanes, PAHs, semivolatiles, and pesticides were analyzed using a high resolution time-of-flight (HRTOF) mass spectrometer—Pegasus GC-HRT (LECO Corporation, Saint Joseph,MI)—at 10 spectra-per-second (m/z40–300) in high resolution mode (25,000 at FWHH). The resulting chromatographic peaks were automatically found, deconvoluted, and curated into an Accurate Mass Library (AML).
Super-resolution single molecule localization microscopy of the exocytotic machinery underlying insulin secretion.
Heriot-Watt Univeristy

Single molecule imaging of the tSNARE proteins involved in insulin secretion.
Automated Sample Preparation of Whole Blood for Therapeutic Drug Monitoring and Diagnostics by LC-MS using a Commercial Autosampler
1 University of Applied Sciences and Arts Northwestern Switzerland FHNW, Institute for Chemistry and Bioanalytics , Gründenstrasse 40, 4132 Muttenz; 2 CTC Analytics AG; Industriestrasse 20, CH-4222 Zw

In this poster the parameters necessary to automatically prepare whole blood samples for online LC-MS applications in the field of diagnostics and TDM have been investigated. A strategy and the most important parameters are shown for the optimization of a PAL RTC autosampler
for the preparation of whole blood samples.
Development and Application of Quantitative Immunoassays for Major Milk Allergens Bos d 5 (β-lactoglobulin) and Bos d 11 (β-casein)
1. Indoor Biotechnologies, Ltd., Cardiff, Wales, UK. 2. INRA, Gif-sur-Yvette, France

In this study, we sought to develop accurate, sensitive and reliable assays that would enable quantification of multiple milk allergens.

Diagnosing Coral disease with Metabolomic Markers
NYUAD

Application of untargeted metabolomics for the identification of disease markers in corals
Quantitative Cell-Based Bioassays for Individual and Combination Immune Checkpoint Immunotherapy Targets
Promega Corporation

Immune checkpoint receptors are promising new immunotherapy
targets for the treatment of a variety of diseases including cancer and
autoimmune-mediated disorders. We developed a suite of cell-based
bioluminescent reporter bioassays for individual and combination
immune checkpoint immunotherapy targets including: PD-1 (PD-L1 or PD-L2), CTLA-4, LAG-3, TIGIT, PD-1+TIGIT, GITR, 4-1BB, CD40, and OX40.

A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources
Biological Industries

An overview of a novel SF, XF differentiation system which enables achieving defined conditions for rapid generation of differentiated hMSCs towards tissue engineering and drug screening applications
Application Notes
Characterization of Protein-Protein Interactions using Triple Detection Size Exclusion Chromatography (SEC-TD)
Malvern Instruments Limited

In this application note, triple detection size exclusion chromatography (SEC-TD) is used to understand the ability of proteins to form ordered, structured complexes. The controlling mechanism behind these protein complexes is fundamental to our knowledge of protein signaling pathways and the physiological responses they control.
Characterization of IgG Monomers & Their Aggregates
Malvern Instruments Limited

A comparison between column calibration & multi-detection SEC.
Differentiation of Polymer Branching and Composition Using the Mark–Houwink Plot
Malvern Instruments Limited

In this application note, we will show, using polystyrene, how to separate the effects of a structural difference induced by a compositional change (bromination) and the structural change induced by polymer chain branching using the Mark- Houwink plot.
Automated Sample Preparation - Analysis of 25-OH-Vitamin D3 and 25-OH-Vitamin D2 by LC/MS/MS
Beckman Coulter Life Sciences


Automated Sample Preparation for the Monitoring of Pharmaceutical and Illicit Drugs by LC-MS/MS
Beckman Coulter Life Sciences


Automated Sample Preparation for the Monitoring of Ethanol Metabolites in Urine by LC-MS/MS
Beckman Coulter Life Sciences


Automating Protein Digestion for Reproducible Proteomics
Beckman Coulter Life Sciences


Use Of Microcalorimetry And Its Correlation With Size Exclusion Chromatography For Rapid Screening Of The Physical Stability Of Large Pharmaceutical Proteins In Solution
Malvern Instruments Limited


How to Maximize Absolute Molecular Weight Measurement Accuracy: Synthetic Polymers
Malvern Instruments Limited


Structural Elucidation of Dextrans and other Polysaccharides using OMNISEC Multi- Detection GPC
Malvern Instruments Limited

A series of dextran samples ranging in molecular weight from about 1– 650 kDa are characterized using OMNISEC. Structural comparisons to other polysaccharides, gum arabic and pectin are presented.
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