Corporate Banner
Satellite Banner
Chromatography
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Owlstone Introduces UltraFAIMS for Improved Mass Spectrometry

Published: Monday, June 16, 2014
Last Updated: Thursday, June 12, 2014
Bookmark and Share
A low-cost accessory for mass spectrometers that provides an additional dimension of high-speed separation by ion mobility.

Owlstone Ltd announced the commercial launch of its UltraFAIMS series of products, developed to enhance mass spectrometry (MS) by quickly simplifying complex mass spectra, separating isobaric ions and reducing background. The new products were launched today at the 62nd ASMS Conference on Mass Spectrometry and Allied Topics, June 15th-19th 2014, Baltimore, MD.

UltraFAIMS is a miniaturized chip-based FAIMS (Field Asymmetric Ion Mobility Spectrometry) platform technology developed by Owlstone. UltraFAIMS can be interfaced with mass spectrometers to provide an additional in-source separation stage for isobaric analytes, protein and peptide charge states, large and small proteins, isomers and conformers. Miniaturizing the chip has allowed Owlstone to generate much higher field strengths than have been available in FAIMS systems up to now. This means that a greater range of analytes can be separated, at faster speeds, without compromising the system sensitivity. 

The newly-launched UltraFAIMS ion filters incorporate the miniaturized FAIMS chip, and can be retrofitted onto mass spectrometers. The low-cost modules have been shown to improve mass accuracy and detection limits, increase the level of quantitation and dynamic range, reduce background and provide additional real-time separation within LC peaks. Once installed, UltraFAIMS can be turned on to provide extra separation, or turned off to allow transmission of all species simultaneously – there is no need to remove it from the system when not in use. Its small size (height, width and depth ≈ 20cm) and straightforward interface mean it can easily be added to an established laboratory setup. 

Professor Colin Creaser, Head of the Centre for Analytical Science at Loughborough University, whose group has been working with a pre-production instrument, said: “Owlstone’s chip-based FAIMS system is very straightforward to use and has demonstrated potential for the analysis of small molecules, peptides and proteins. We are particularly excited about its ability to enhance high-throughput mass spectrometry applications by separating target ion responses from isobaric and isomeric ions.”

The product range includes:

• UltraFAIMS-A1, compatible with Agilent 6130/6150 (SQ), 6460 (QQQ), 6230 (TOF) and 6530/6540 (QTOF)
• UltraFAIMS-T1, compatible with Thermo Exactive Series & LTQ-Orbitrap
• UltraFAIMS-DK1 (developer kit), which is available for instrument developers or vendors who wish to interface with a mass spectrometer or source for which an off-the-shelf interface isn’t currently available


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,900+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Metabolite Promotes Cancer Cell Transformation
Researchers have identified a metabolite that promotes cancer cell transformation and colorectal cancer spread.
Cocaine Test Could Lead to Rapid, Low Cost Roadside Testing
Scientists develop urine and oral fluid diagnostic test for cocaine, utilising a compact mass spectrometer.
The Benefits of a Mediterranean-style Diet
A Western-style diet, with more omega-6 fatty acids than the Mediterranean, dysregulates lipid signaling in aged mice and promotes inflammation.
Are Sweeteners as Natural as We Think?
New research study supports stevia’s naturality by identifying nine required molecules present in the dried stevia leaf.
Alarming Glyphosate Levels Found in Foods
Glyphosate has been found at alarming levels in a wide range of best-selling foods across the U.S.
Peer Review is in Crisis, But Should be Fixed, Not Abolished
After the time to get the science done, peer review has become the slowest step in the process of sharing studies, and some scientists have had enough.
Rapid Identification of Illicit Designer Drugs
New technique can identify commonly used illicit compounds in as little as 15 seconds.
Enhancing On-line Biological Sample Processing
New techniques are required to meet emerging demands on biopharmaceutical analysis.
Early Warning System for Colorectal Cancer
Potential new diagnostic tool identified for the second most common cancer in the world.
Steroid Screening with LC-MS
Researchers developed and validated a label-free assay for detection of steroid activity using LC-MS techniques.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!