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Trace Level Analysis of Perchlorate and Bromate in Various Water Matrices using Suppressed Ion Chromatography
Dr. Jay Gandhi, DR. Stuart Procter

Bromate and Perchlorate are ubiquitous analytes in various water matrices and analysis in trace level is a challenge

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Identification and classification of antifouling compounds secreted by anti MIC microorganisms. A metabolomic analysis.
Albillos SM; Balaña-Fouce R; Montero O; Barreiro-Mendez C; Blas-Galindo E; Barros-García R; Guedella-Bustamante E; Ullán RV

BIOCORIN project, aims to develop a green alternative to the coatings and solutions used up to date for MIC corrosion control. Some of the results of this project are presented here, with the identification of several relevant antifouling compounds secreted by environmentally isolated anti-MIC strains of microorganisms via a metabolomic approach.

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Employing Design of Experiments (DoE) to Evaluate the Robustness of an Automated Content Uniformity Method for the Triple Fixed Dose Combination Tablets
Irena Maksimovic, Dongsheng Bu, David Lloyd

The Design of Experiments study was employed to optimize the operating ranges of the critical sample extraction parameters for the content uniformity determination of three actives in Triple Fixed Dose Combination tablets using Tablet Processing Workstation bench-top robotic system.

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Employing Design of Experiments (DoE) to Evaluate the Robustness of an Automated Content Uniformity Method for the Triple Fixed Dose Combination Tablets
Irena Maksimovic, Dongsheng Bu, David Lloyd

The Design of Experiments study was employed to optimize the operating ranges of the critical sample extraction parameters for the content uniformity determination of three actives in Triple Fixed Dose Combination tablets using Tablet Processing Workstation bench-top robotic system.

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Investigation of Chemical Contaminants in Soils Following Superstorm Sandy
Amy C Mandigo*, Dana J DiScenza*, Alison R Keimowitz†, and Neil Fitzgerald*

Investigation of Chemical Contaminants in Soils Following Superstorm Sandy

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Determination of Metabolically Unstable Drugs in Blood by Heat-Stabilized DBS and LC-MS/MS

The aims of this work were to investigate drug stability prior to, during and after blood spot sampling, using procaine, prulofloxacine, esmolol, and acetylsalisylic acid as examples of drug compounds with limited stability and to compare conventional DBS sampling procedure with DBS sampling including heat stabilization.

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Determination of Metabolically Unstable Drugs in Blood by Heat-Stabilized DBS and LC-MS/MS
Charlotta Göransson; Karl Sköld; David Zeeberg; Gunnar Hägglund; Eskil Hermansson; Peter Abrahamsson and Martin Ahnoff

The aims of this work were to investigate drug stability prior to, during and after blood spot sampling, using procaine, prulofloxacine, esmolol, and acetylsalisylic acid as examples of drug compounds with limited stability and to compare conventional DBS sampling procedure with DBS sampling including heat stabilization.

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LC/MS/MS Quantitation of Eicosapentaenoic Acid in Rat Plasma
Rachel Sun, Jordan Nally, Tim Shoaf

Eicosapentaenoic acid (EPA) is an omega-3 fatty acid, which has been documented to be important in biochemical and physiological processes including inflammatory response, blood clotting and the immune system. Eicosapentaenoic acid (EPA) appears in different forms in the blood including triglyceride, ethyl ester, or free acid. In this work we presented an LC/MS/MS method to quantitate the total eicosapentaenoic acid in rat plasma with a 96-well plate format.

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Ion Chromatography ICP-Q-MS for the Detection of Arsenic Species in Apple Juice
Daniel Kutscher, Shona McSheehy-Ducos, Julian Wills and Detlef Jensen

Interest in the determination of Arsenic species in fruit juices has been triggered by recent media reports in the United States claiming that some apple juices may contain high amounts of Arsenic. Inorganic forms of Arsenic (As3+ and As5+) are highly toxic, whereas the organic forms (e.g. arsenobetaine) are not considered toxic. A robust IC-ICP-MS system was developed and shown to be a highly selective and sensitive technique for determination of trace element species.

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Showing Results 21 - 30 of 57
Scientific News
Study Aims to Develop Breath Test for COPD
A new clinical iniative, lead by NYU Langone Medical Center, aims to determine a breath test’s effectiveness to identify volatile organic compounds (VOCs) in human breath that are biomarkers of chronic obstructive pulmonary disease (COPD).
Salamander Skin Peptide Promotes Wound Healing in Mice
New research suggests that the peptide tylotoin exerts the promotion of wound healing with epidermal growth factor in a murine model of a full thickness dermal wound.
Comparison of Caffeinated and Decaffeinated Coffee - Implications for Alzheimer's Disease
Researchers from the National University of Singapore successfully demonstrated the viability of GC-TOF-MS as an analytical platform for metabolomics analysis of coffee samples.
High Capacity Antibody Purification
Researchers from the A*Star Bioprocessing Technology Institute have used magnetic nanoparticles to break the capacity barrier for antibody purification.
Embalming Study ‘Rewrites’ Key Chapter in Egyptian History
New evidence to suggest that the origins of mummification started in ancient Egypt 1,500 years earlier than previously thought.
RP HPLC Retention Behaviours in Carotenoids Analysis
The efficiency of the separation process in reversed-phase HPLC is highly dependent on the binary hydro-organic mobile phase composition and surface properties of the packing material.
Identification of Psoriatic Arthritis Mediators in Synovial Fluid
This study represents the most comprehensive proteomic analysis of psoriatic arthritis synovial fluid, to date.
Simultaneous Determination of Six Flame Retardants in Water
The work aimed to develop an analytical procedure for the extraction and simultaneous determination of selected flame retardants.
Using LC-MS to Analyse Sulfonamides in Food Grade Honey
Sulfonamides are one of a number of groups of chemicals whose presence in honey is limited by international regulations.
Assessing Anticancer Drugs Efficacy by Amino Acid Metabolomics
Researchers aimed to develop a method that determines the therapeutic efficacy of anticancer drugs based on the changes in amino acid metabolism at the cellular level.
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