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  Events - October 2012


BioCrys2012 - Fundamentals of Modern Methods of Biocrystallography

20 Oct 2012 - 27 Oct 2012 - Oeiras, Portugal



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Topics: from fundamentals – such as symmetry, point groups and crystal systems, basic diffraction physics, reciprocal space and the Ewalds sphere, radiation damage, data processing, symmetry in the diffraction pattern, structure factors, and Patterson function – to modern methodologies including molecular replacement, SAD, MAD, MIR and maximum likelihood phasing, direct methods, density modification, refinement, model building, twinning and structure validation. Key challenges in sample preparation and crystallization of proteins will also be covered, as well as difficulties in structural studies of membrane proteins and the future applications of free electron lasers in structural biology.



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