Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>Events>This Event
  Events - May 2014

47th Course of the International School of Crystallography

30 May 2014 - 08 Jun 2014 - Erice, Italy

Bookmark and Share

Diseases, from bacterial and viral infections to cancer to chronic maladies, are still among the greatest problems for mankind, in spite of tremendous progress in genetics, biology, and chemistry.  Approaches to developing new treatments have changed over time, and so have the methodologies used, in order to solve the varied, new, challenging problems that may happen on the path to drug discovery.  Together with ever-evolving experimental techniques, a variety of computational approaches have been applied at the various stages of the drug design process, and in the past two decades structure-based drug design has become one of the mainstream approaches.  This method can be used to target protein-ligand and protein-protein interactions and nowadays is applicable to all aspects of drug discovery, including lead identification, lead optimization, ADMET prediction, and drug repurposing. 

The purpose of the course is dual:

1) It will provide a review of the fundamentals and the application of crystallography to drug design, and an evaluation of the technology at the present state.

2) It will review the progress in this field and summarize the application and results to current fields of interest.  

In addition to lectures, there will be hands-on workshops providing training in using modern computer programs.

The topics that will be covered are:

- Targeting Resistance in Design of Anti AIDS Drugs

- Molecular Modeling and Drug Design

- Targeting Protein-Protein Interactions

- Drug Design Targeting Bromodomains

- Targeting GPCRs for Drug Design

- Targeting Influenza Virus Polymerase

- The Small Molecule Universe

- Molecular Obesity and Other Addictions in Drug Discovery

- Energetics of Protein-Ligand Interactions

- Docking Experiences and Expectations

- Structure of Human G-Protein Coupled Receptor

- Using ARP/WARP for Structure-Based Drug Design

- Antibody Technologies to Stabilize Targets for NCE Screening

- Drug Design Tales from AstraZeneca

- High Resolution Protein-Ligand Interactions by X-rays and Neutrons

- Virus Structure and Antiviral Drug Design

- Structure-Based Design of Drugs Against Diabetes

- Membrane Protein Structure

- Structural Bioinformatics

- Protein Aggregation and Drug Design

- Turning on Enzymes with Small Molecules

Further information
Scientific News
Step Toward Controlling Zika and Dengue Fever
UCLA scientists and colleagues identify structure of a molecule that kills mosquitoes carrying malaria and West Nile virus.
Uncovering Bacteria's Antibiotic Resistance
Scientists determine the structure and mechanisms of enzyme that deactivates an important antibiotic - rifampicin.
Diamond Light Source Scientists Publish 5000th Paper
Diamond’s milestone paper reveals findings on embryonic defects.
3D-Printing in Science: Conference Co-Staged with LABVOLUTION
LABVOLUTION 2017 will have an added highlight of a simultaneous conference, "3D-Printing in Science".
Cone Snail Venom Reveals Insulin Insights
Researchers found that a fast-acting insulin from the cone snail can bind and activate the human insulin receptor.
Designing Drugs with a Whole New Toolbox
Researchers develop methods to design small, targeted proteins with shapes not found in nature.
Protein Studies Discover Molecular Secrets
Two protein studies have mapped proteins that reveal the secrets to recycling carbon and healing cells.
Antibodies Block Norovirus’ Entrance into Cells
Scientists have uncovered a mechanism in the human body that targets and successfully blocks noroviruses.
Protein Findings Could Lead To New Class Of Antibiotics
Atomic-level images of a protein have revealed a characteristic that could form a basis of new antibiotic approach.
Worms Point Way Toward Viral Strategies
Rice University wins NIH grant to study how nematodes handle gastrointestinal viruses.
Scroll Up
Scroll Down

SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,100+ scientific videos