BioCryst Announces Positive Results from Two Phase 2 Trials Wednesday, August 01, 2012 The results confirm the safety profile of ulodesine through 52 weeks in Patients with gout. Identifying Protein 'Pockets' that Block Hallucinogens Wednesday, August 01, 2012 Psychoactive drugs work by binding proteins in our brains and bodies and although these proteins have been a mystery, new research from the University of North Carolina is illuminating their structures. Delving Into the Molecular Mechanism Behind Deep-Sea Bacteria’s Pressure Tolerance Wednesday, August 01, 2012 A Japanese research team have identified a structural change that confers pressure-resistant properties on a particular protein found in bacteria. Crystallization of SHARPIN Using an Automated Two-Dimensional Grid Screen for Optimization Wednesday, August 01, 2012 To obtain insight into the oligomeric state of SHARPIN, researchers from the National Institute for Medical Research crystallized residues 1–127 encompassing the region responsible for self-association. New Insights for Drug Design from the X-ray Crystallographic Structures of GPCRs Wednesday, July 18, 2012 This study looks at recent developments in high-resolution imaging of GPCR structures and conformational changes upon activation, and how this knowledge can help in the design of potent drugs. Scientists Solve Structure of Important Protein in Energy Storage of Cells Wednesday, July 18, 2012 Scientists at Trinity College Dublin, using a highly specialised crystallography technique have solved a large protein structure that will increase our understanding of energy generation and storage in cells. The Role of Protein Crystallography in Defining the Mechanisms of Biogenesis and Catalysis in Copper Amine Oxidase Tuesday, July 17, 2012 This review focuses on cofactor biogenesis and catalysis in the topaquinone-containing CAOs, with a particular emphasis on the role X-ray crystallography has played in understanding these two processes. Wyatt Technology Celebrates 30th Years Thursday, July 12, 2012 Company will toast 300 years of macromolecular characterization expertise at the 2012 International Light Scattering Colloquium. Calixar and Synthelis Team Up to Provide Unique Membrane Protein Services Friday, July 06, 2012 Partnership will enable life sciences researchers and industry to access a comprehensive and innovative range of services to obtain currently unavailable therapeutic targets.
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