NIH Common Fund Researchers Uncover Structure of Important Target for Drug DesignResearchers have uncovered a potent class of small molecules that selectively turn on the S1P1 receptor.
Structure of Complex Zeolite explains its Role in Naphtha-to-Diesel ConversionUsing electron crystallography scientists have determined that a new zeolite has a unique structure containing discrete pores of different dimensions that are connected together.
Protein Dynamics at Eph Receptor-Ligand Interfaces as Revealed by Crystallography, NMR and MD SimulationsThe research highlights the key role of protein dynamics in Eph-ephrin signalling, demonstrating how this would benefit future design of agonists/antagonists targeting Eph receptors.
X-ray Diffraction of Protein Crystal Grown in a Nano-liter Scale Droplet in a Microchannel and Evaluation of Its ApplicabilityResearchers from Kyushu University describe the technical aspects of the in-situ X-ray diffraction of a protein crystal prepared by a nanodroplet-based crystallization method.
Crystal Structure of Urea Carboxylase Provides Insights into the Carboxyltransfer ReactionResearch from the Chinese Academy of Sciences could shed light on the mechanism of these enzymes' catalysis.
Vitamins could lead to the Design of Novel Drugs to Combat MalariaThe research will enable scientists to learn more about the nature of the enzymes required for vitamin biosynthesis by the malaria causing pathogen Plasmodium.
A New Generation of Crystallographic Validation Tools for the Protein Data BankThis report presents the conclusions of the X-ray Validation Task Force of the worldwide Protein Data Bank.
Temperature Controlled Stage Used in Crystallisation ProcessesLinkam Scientific Instrument report on the work of Professor Yves Henri Geerts from the Université Libre de Bruxelles where he uses a specially designed temperature stage to study crystallisation processes in opto-electronic thin films.
CSHL Team Solves a Protein Complex’s Molecular Structure to Explain Role in Gene SilencingScientists from Cold Spring Harbor Laboratory and their collaborators at St. Jude’s Research Hospital have discovered new details of how various domains of the protein complex contribute to heterochromatin assembly and gene silencing.
Noncovalent Polymerization of Mesogens Crystallizes Lysozyme: Correlation Between Nonamphiphilic Lyotropic Liquid Crystal Phase and Protein Crystal FormationResearchers from Syracuse University we report the use of organic salts that can form a class of unusual nonamphiphilic lyotropic liquid crystals to crystallize the protein lysozyme.
