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Non-Destructive Evaporation Technology Improves Polymorph Screening

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Genevac announces eXalt - an exciting new non-destructive evaporation technology developed with partners in the field of pharmaceutical small molecule crystallisation. eXalt enables a wide range of solvents and multiple actives to be evaporated all at the same slow rate, and under the same conditions, giving the user unprecedented control of the crystallisation process. This is achieved using a special holder which allows a selection of baffles to be placed on top of samples vials to slow the evaporation rate of the more volatile solvents. Size and number of baffles are selected to be most restrictive to the least volatile solvents.  In some cases no baffle is required. The holder is then placed in a Genevac HT Series Evaporator which cycles the samples at atmospheric and at a slightly reduced pressure for the duration of the process. eXalt has found application in labs that perform tasks including first time crystallisation of amorphous forms, recrystallisation of samples which have only a few known forms, removing a hydrate, solvent screening studies to find the most suitable conditions to take forward in development, high throughput co-crystallisation screens and studies to confirm stable isoforms.

Product Non-Destructive Evaporation Technology Improves Polymorph Screening
Company Genevac
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