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Human Astrovirus Structure Could Lead to Therapies, Vaccines
Study shows where neutralizing antibody binds to human astrovirus, a leading cause of viral diarrhoea in children, elderly, and the immune-compromised.
Drug Design Strategy to Improve Breast Cancer Treatment
Scientists develop novel structure-based drug design strategy aimed at altering the basic landscape of hormone-driven breast cancer treatment.
Crystals, Super Magnets in Drug Discovery
Scientists have produced larger superparamagnetic crystals that could revolutionise drug delivery.
Peer Review is in Crisis, But Should be Fixed, Not Abolished
After the time to get the science done, peer review has become the slowest step in the process of sharing studies, and some scientists have had enough.
Snapshots of Chemical Flipping a Biological Switch
X-ray laser gets first real-time snapshots of a chemical flipping a biological switch, opening new path to understanding how RNA works.
Uncovering Elusive Proteins
Researchers have determined the complete structure of elusive proteins, known as tetraspanins, for the first time.
Cannabinoid Receptor Structure Revealed
Scientists provided a detailed view of the primary molecule through which cannabinoids exert their effects on the brain. The findings might help guide the design of more targeted medicines with fewer side effects.
Alzheimer’s Treatment Moves a Step Closer
Merck scientists have reported the discovery of verubecestat, a structurally unique, orally bioavailable small molecule that has been shown to target the most visible sign of the disease in the brain.
Study Unocovers Cancer-Linked Protein’s Associates
Researchers have developed a new list of nearly 100 potential partners of a cancer-linked enzyme by studying its interactions with other proteins.
Scientists Uncover Why Hepatitis C Vaccine is Difficult to Make
Scientists have uncovered one reason why a successful hepatitis C vaccine continues to be elusive.

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Label-Free Binding Analysis Trends 2014
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The main objectives were to comprehensively document current experience of and future interest in investigating biomolecular interactions and binding analysis using LF technologies. The study also examined in detail the changing market landscape, application areas and future purchasing plans.

The report is a source of valuable information for vendors developing LF binding analysis systems, and provides the latest market information on this rapidly changing area.

Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Research segments, active in either small molecule drug discovery or protein and biologics characterization.

The survey looked at the following aspects of LF binding analysis as practiced today (2014) and in some cases as predicted for the future (2016): areas where biomolecular binding analysis is primarily used; techniques used to assess binding interactions; how respondent’s research objectives are aided by LF technology; classification that most closely describes an LF binding assay; vendor’s LF technologies currently available in respondent’s lab; most recognizable LF instrument brands; current perception of different LF instrument suppliers; the most common limitation experienced using an LF assay approach: applications that LF binding assays are best suited for; application areas where LF binding assays are expected to gain most popularity over coming years; processes which could most benefit from the use or expanded use of LF binding assays; integration of any LF instruments/devices used for binding analysis into automated robotic systems; importance given to some application capabilities when purchasing a new LF system for binding analysis; attributes of a new label-free binding analysis system that impact a purchasing decision; what influences the timing of a decision to purchase a LF system; likelihood of purchasing a new LF instruments for binding analysis over the coming years; the primary use of respondent’s next LF instrument purchase; the top two vendors from which respondents are most likely to purchase a new LF instrument; annual capex and consumable budgets for LF binding analysis; resources most relied upon to learn about/gather information on new LF technologies and assays; conferences attended in the last 12 months; publications subscribed to, regularly read or visited online; and any unmet needs in LF binding analysis.

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