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Secrets of a Deadly Virus Family Revealed
Scripps Research scientists uncover the glycoprotein structure of LCMV. The findings could guide development of treatments for Lassa fever.
Serotonin Transporter Structure Revealed
Researchers determined the 3-D structure of the serotonin transporter and visualized how two common antidepressants interact with the protein.
Zika Virus Structure Revealed
Team at Purdue becomes the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines.
Half a Million-Dollar Tick
How proteins present in tick saliva prevent the immune system from running amok.
Promising Model for Hantavirus Drug Design
X-ray crystallography provides drug template against disease transmitted by small rodents.
A Crystal Clear View of Biomolecules
Fundamental discovery triggers paradigm shift in crystallography.
'Molecular Movie' Opens Door to New Cancer Treatments
An international team of scientists led by the University of Liverpool has produced a 'structural movie' revealing the step-by-step creation of an important naturally occurring chemical in the body that plays a role in some cancers.
Crouching Protein, Hidden Enzyme
A new study led by scientists at The Scripps Research Institute (TSRI) and the University of California (UC), Berkeley shows how a crucial molecular enzyme starts in a tucked-in somersault position and flips out when it encounters the right target.
Spotlight on Acoustic Liquid Handling
Journal of Laboratory Automation special issue highlights how acoustic liquid handling enables breakthrough innovations.
3D Images of Enzymes May Lead to Improved Antibiotics
Research advances understanding of how crucial proteins function.

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Label-Free Binding Analysis Trends 2014
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The main objectives were to comprehensively document current experience of and future interest in investigating biomolecular interactions and binding analysis using LF technologies. The study also examined in detail the changing market landscape, application areas and future purchasing plans.

The report is a source of valuable information for vendors developing LF binding analysis systems, and provides the latest market information on this rapidly changing area.

Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Research segments, active in either small molecule drug discovery or protein and biologics characterization.

The survey looked at the following aspects of LF binding analysis as practiced today (2014) and in some cases as predicted for the future (2016): areas where biomolecular binding analysis is primarily used; techniques used to assess binding interactions; how respondent’s research objectives are aided by LF technology; classification that most closely describes an LF binding assay; vendor’s LF technologies currently available in respondent’s lab; most recognizable LF instrument brands; current perception of different LF instrument suppliers; the most common limitation experienced using an LF assay approach: applications that LF binding assays are best suited for; application areas where LF binding assays are expected to gain most popularity over coming years; processes which could most benefit from the use or expanded use of LF binding assays; integration of any LF instruments/devices used for binding analysis into automated robotic systems; importance given to some application capabilities when purchasing a new LF system for binding analysis; attributes of a new label-free binding analysis system that impact a purchasing decision; what influences the timing of a decision to purchase a LF system; likelihood of purchasing a new LF instruments for binding analysis over the coming years; the primary use of respondent’s next LF instrument purchase; the top two vendors from which respondents are most likely to purchase a new LF instrument; annual capex and consumable budgets for LF binding analysis; resources most relied upon to learn about/gather information on new LF technologies and assays; conferences attended in the last 12 months; publications subscribed to, regularly read or visited online; and any unmet needs in LF binding analysis.

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