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Scientific News
Protein Crystalline Frameworks: A New Class of Materials
Scientists at the Helmholtz Center Berlin (HZB) along with researchers at China’s Fudan University have characterized a new class of materials called protein crystalline frameworks (PCFs).
Worm Virus Details Come to Light
Rice University scientists have won a race to find the crystal structure of rare nematode virus, known to infect the most abundant animal on Earth.
Structure of Molecular Machine for Targeted Viral DNA Destruction Determined
The MSU-led research provides the first detailed blueprint of a multi-subunit “molecular machinery” that bacteria use to detect and destroy invading viruses.
Flu’s Mechanisms Clues Uncovered
Researchers from Rice University and Baylor College of Medicine have analyzed how influenza-related proteins help infect cells.
Innovative Technology Enables First Crystal Structure of mGlu5 Transmembrane Domain to be Determined
Several novel drug candidates have been identified to help treat specific neuropsychiatric disorders.
Neutron Crystallography Resolves Long-Standing Molecular Mystery
Research has implications for understanding of oxidative processes within living cells which is crucially important for drug development.
Considering the ‘Anticrystal’
Researchers have evidence of a new concept, the anticrystal, a theoretical solid that is completely disordered.
How Developing Neurons Sense a Chemical Cue
An embryo organizes itself into left and right halves as it grows. But a certain set of nerve cells do something unusual: they cross from one side to the other.
High-speed Snapshots of Biomolecules
PETRA III pioneers protein serial crystallography at synchrotrons.
Stanford Researchers Discover Immune System’s Rules of Engagement
Study finds surprising similarities in the way immune system defenders bind to disease-causing invaders.

Approaches to the Discovery of Small-molecule MDM2-p53 Inhibitors
Dr Ian Hardcastle, Newcastle University, speaking at Discovery Chemistry Congress 2013.

Chemical Biology Approaches to Target Protein Modification in Disease
Megan Wright, Imperial College London, speaking at Discovery Chemistry Congress 2013.

Robust Three-dimensional Tools to Design Inhibitors Against Drug Targets Which Lack Explicit Specificity
Dr. Moses Mohandas Prabu, The Commonwealth Medical College, speaking at Discovery Chemistry Congress 2013.

ESPRIT: High Throughput Screening for Soluble Expression Constructs of Difficult-to-express Proteins
Darren Hart, European Molecular Biology Laboratory, speaking at European Lab Automation 2012

Fragment-Based Screening and Structure-Based Design at ICR: Discovering High Quality Leads in Cancer Drug Discovery
Rob Van Montfort, Institute of Cancer Research, speaking at Discovery Chemistry Conference 2012.

NMR as a Tool for Examining Mechanisms of Transport and Inhibition in CLC “Chloride Channels”
Shelley Elvington, Stanford University, speaking at Ion Channel Targets 2011.

Old Structures - New Targets for Antivirulence Salicylidene Acylhydrazide Compounds
Mads Gabrielsen, Post Doc, University of Glasgow, speaking at Advances in Protein Crystallography 2010.

Novel Methodology for Improving Crystal Quality in Microbatch
Sahir Khurshid, Post Doc, Imperial College London, speaking at Advances in Protein Crystallography 2010.

The OPPF-UK Pipeline for Structural Proteomics of Glycoproteins
Joanne Nettleship, Senior Scientist, Oxford Protein Production, speaking at Advances in Protein Crystallography 2010.

Highways, Biways, and Detours in the Road to Crystallization
Terese Bergfors, Principle Investigator, Uppsala University, speaking at Advances in Protein Crystallography 2010.

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