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Escape Prevention
Studying flu virus structure brings us a step closer to a permanent vaccine.
Scientists Decode Structure at Root of Muscular Disease
Researchers at Rice University and Baylor College of Medicine have unlocked the structural details of a protein seen as key to treating a neuromuscular disease.
A Natural Light Switch
MIT scientists identify and map the protein behind a light-sensing mechanism.
First Complete Structural Study Of A Pegylated Protein
Significant data obtained at NUI Galway reports first crystal structure of a protein modified with a single PEG chain.
Cellular Contamination Pathway for Heavy Elements Identified
Berkeley Lab scientists find that an iron-binding protein can transport actinides into cells.
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
New Mathematics Advances the Frontier of Macromolecular Imaging
Berkeley Lab’s M-TIP solves the reconstruction problem for fluctuation X-ray scattering.
Diamond Helps Develop New Way of Studying the Tiniest Microcrystals
Researchers have developed a new type of sample holder for ‘serial protein crystallography’.
Crystal Clear Images Uncover Secrets of Hormone Receptors
NIH researchers gain better understanding of how neuropeptide hormones trigger chemical reactions in cells.
TOPLESS Plants Provide Clues to Human Molecular Interactions
Scientists at Van Andel Research Institute have revealed an important molecular mechanism in plants that has significant similarities to certain signaling mechanisms in humans, which are closely linked to early embryonic development and to diseases such as cancer.

Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase
Rob van Montfort, The Institute of Cancer Research, speaking at Discovery Chemistry Congress 2015.

Choosing & Using Fragments in the Generation of Selective Kinase Inhibitors
Lee Walmsley, Vernalis Ltd, speaking at Discovery Chemistry Congress 2015.

Identification of Atg-8–Atg 3 protein-protein interaction inhibitor
Jürgen Bosch, Johns Hopkins University, speaking at Drug Discovery and Development 2014

Approaches to the Discovery of Small-molecule MDM2-p53 Inhibitors
Dr Ian Hardcastle, Newcastle University, speaking at Discovery Chemistry Congress 2013.

Chemical Biology Approaches to Target Protein Modification in Disease
Megan Wright, Imperial College London, speaking at Discovery Chemistry Congress 2013.

Robust Three-dimensional Tools to Design Inhibitors Against Drug Targets Which Lack Explicit Specificity
Dr. Moses Mohandas Prabu, The Commonwealth Medical College, speaking at Discovery Chemistry Congress 2013.

ESPRIT: High Throughput Screening for Soluble Expression Constructs of Difficult-to-express Proteins
Darren Hart, European Molecular Biology Laboratory, speaking at European Lab Automation 2012

Fragment-Based Screening and Structure-Based Design at ICR: Discovering High Quality Leads in Cancer Drug Discovery
Rob Van Montfort, Institute of Cancer Research, speaking at Discovery Chemistry Conference 2012.

NMR as a Tool for Examining Mechanisms of Transport and Inhibition in CLC “Chloride Channels”
Shelley Elvington, Stanford University, speaking at Ion Channel Targets 2011.

Old Structures - New Targets for Antivirulence Salicylidene Acylhydrazide Compounds
Mads Gabrielsen, Post Doc, University of Glasgow, speaking at Advances in Protein Crystallography 2010.

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