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Scientific News
How the Environment Contributes to Human Diseases
Using a new imaging technique, NIH researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures.
Protein-engineered Cages Aid Studies of Cell Functions
The Cages, from researchers at Tokyo Institute of Technology, to deliver an important signalling molecule, carbon monoxide, into cells.
Scientists Discover Bacteria’s Clever Defence Mechanism
Structure of EzrA protein could help identify new antibiotic targets.
UCLA Biochemists Build Largest Synthetic Molecular ‘Cage’ Ever
New nanoscale protein container could lead to synthetic vaccines and offer a way to deliver medicine inside of human cells.
SLAC X-ray Laser Brings Key Cell Structures into Focus
Experiment is Important Step Toward Atomic-Scale Imaging of Intact Biological Particles.
A Greasy Way to Take Better Protein Snapshots
Researchers used a newly developed grease to suspend small crystals of lysozyme, glucose isomerase, thaumatin, and fatty acid-binding protein type-3.
Scripps Research Institute Scientists Capture Picture of 'MicroRNA' in Action
The Findings Will Help Guide Drug Design.
Team Discovers How Microbes Build a Powerful Antibiotic
Researchers discovery opens up new avenues of research into thousands of similar molecules.
Major Step Forward in Understanding of Viruses
Scientists unlock exact structure of Hepatitis A virus.
Crystallizing the DNA Nanotechnology Dream
Scientists have designed the first large DNA crystals with precisely prescribed depths and complex 3D features, which could create revolutionary nanodevices.

Identification of Atg-8–Atg 3 protein-protein interaction inhibitor
Jürgen Bosch, Johns Hopkins University, speaking at Drug Discovery and Development 2014

Approaches to the Discovery of Small-molecule MDM2-p53 Inhibitors
Dr Ian Hardcastle, Newcastle University, speaking at Discovery Chemistry Congress 2013.

Chemical Biology Approaches to Target Protein Modification in Disease
Megan Wright, Imperial College London, speaking at Discovery Chemistry Congress 2013.

Robust Three-dimensional Tools to Design Inhibitors Against Drug Targets Which Lack Explicit Specificity
Dr. Moses Mohandas Prabu, The Commonwealth Medical College, speaking at Discovery Chemistry Congress 2013.

ESPRIT: High Throughput Screening for Soluble Expression Constructs of Difficult-to-express Proteins
Darren Hart, European Molecular Biology Laboratory, speaking at European Lab Automation 2012

Fragment-Based Screening and Structure-Based Design at ICR: Discovering High Quality Leads in Cancer Drug Discovery
Rob Van Montfort, Institute of Cancer Research, speaking at Discovery Chemistry Conference 2012.

NMR as a Tool for Examining Mechanisms of Transport and Inhibition in CLC “Chloride Channels”
Shelley Elvington, Stanford University, speaking at Ion Channel Targets 2011.

Old Structures - New Targets for Antivirulence Salicylidene Acylhydrazide Compounds
Mads Gabrielsen, Post Doc, University of Glasgow, speaking at Advances in Protein Crystallography 2010.

Novel Methodology for Improving Crystal Quality in Microbatch
Sahir Khurshid, Post Doc, Imperial College London, speaking at Advances in Protein Crystallography 2010.

The OPPF-UK Pipeline for Structural Proteomics of Glycoproteins
Joanne Nettleship, Senior Scientist, Oxford Protein Production, speaking at Advances in Protein Crystallography 2010.

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