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Scientific News
Using X-rays to Study Ultra-Thin Transistors
Cornell scientists have helped develop a novel process of spreading extremely thin organic transistors, and used synchrotron X-rays to watch how the films crystallize.
Crystal Structure of the Capsular Polysaccharide Synthesizing Protein CapE of Staphylococcus Aureus
This Study presents the first crystal structure of CapE, revealing that this enzyme forms a stable and functional homo-hexamer.
Proton Pathway in Photosynthesis Identified by X-ray Crystallography
A Purdue University-led team has revealed the proton transfer pathway responsible for a majority of energy storage in photosynthesis.
The Cation-π Box is a Specific Phosphatidylcholine Membrane Targeting Motif
Well-defined choline cationaromatic p interactions may be a general motif to anchor proteins to PC-rich bilayers.
Crystallography on the Nanogram Scale
Single Crystal X-ray analysis is a powerful tool for determining the structures of molecules and is widely used both in academic and industrial research.
Proteros and Priaxon Announce Lead Discovery Collaboration on Protein-Protein Interaction Targets
Proteros biostructures GmbH announced they entered into a Lead Discovery Collaboration with Priaxon AG to jointly develop lead compounds for high value protein-protein interaction (PPI) drug targets.
Winners of the Aminoff Prize in Crystallography Announced
Carlo Gatti and Mark Spackman developed experimental and theoretical methods to study electron density in crystals, and using them to determine molecular and crystalline properties.
In Silico Prediction of Interactions between Site II on Human Serum Albumin and Profen Drugs
Binding of a drug molecule to HSA results in increased solubility in plasma, decreased toxicity, and protection against oxidation of the bound molecule.
Study Reveals How Serotonin Receptors Can Shape Drug Effects from LSD to Migraine Medication
A team of scientists has determined and analyzed the high-resolution atomic structures of two kinds of human serotonin receptor.
Findings to Help in Design of Drugs against Virus Causing Childhood Illnesses
New research findings may help scientists design drugs to treat a virus infection that causes potentially fatal brain swelling and paralysis in children.

Chemical Biology Approaches to Target Protein Modification in Disease
Megan Wright, Imperial College London, speaking at Discovery Chemistry Congress 2013.

Robust Three-dimensional Tools to Design Inhibitors Against Drug Targets Which Lack Explicit Specificity
Dr. Moses Mohandas Prabu, The Commonwealth Medical College, speaking at Discovery Chemistry Congress 2013.

Fragment-Based Screening and Structure-Based Design at ICR: Discovering High Quality Leads in Cancer Drug Discovery
Rob Van Montfort, Institute of Cancer Research, speaking at Discovery Chemistry Conference 2012.

NMR as a Tool for Examining Mechanisms of Transport and Inhibition in CLC “Chloride Channels”
Shelley Elvington, Stanford University, speaking at Ion Channel Targets 2011.

Old Structures - New Targets for Antivirulence Salicylidene Acylhydrazide Compounds
Mads Gabrielsen, Post Doc, University of Glasgow, speaking at Advances in Protein Crystallography 2010.

Novel Methodology for Improving Crystal Quality in Microbatch
Sahir Khurshid, Post Doc, Imperial College London, speaking at Advances in Protein Crystallography 2010.

The OPPF-UK Pipeline for Structural Proteomics of Glycoproteins
Joanne Nettleship, Senior Scientist, Oxford Protein Production, speaking at Advances in Protein Crystallography 2010.

Highways, Biways, and Detours in the Road to Crystallization
Terese Bergfors, Principle Investigator, Uppsala University, speaking at Advances in Protein Crystallography 2010.

Towards Eukaryotic Structural Complexomics
Imre Berger, Group Leader, EMBL Grenoble, speaking at Advances in Protein Crystallography 2010.

New Easily Applicable Ideas in Protein Crystallogenesis
Emmanuel Saridakis, Research Fellow, N. C. S. R, speaking at Advances in Protein Crystallography 2010.

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