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Webcasts
Diagnosis of Disorders Affecting Steroid Synthesis and Metabolism by Mass SpectrometryDiagnosis of Disorders Affecting Steroid Synthesis and Metabolism by Mass Spectrometry
Josep Marcos del Aguila, IMIM, speaking at Clinical Applications of Mass Spectrometry 2014.
A Novel Vertically-Integrated Platform for the Discovery and Molecular Characterization of Lung Cancer Stem CellsA Novel Vertically-Integrated Platform for the Discovery and Molecular Characterization of Lung Cancer Stem Cells
Raj Batra, University of California Los Angeles, speaking at Diagnostics & Biomarkers 2015.

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Chromatography Accessories and Consumables Market by Types, Technology & End-users - Trends & Global Forecasts to 2018
MarketsandMarkets

The chromatography accessories and consumables market demands significant investments in R&D in order to constantly come up with new and innovative products and technologies.
Molecular Spectroscopy Market by Technology & Application - Forecast to 2018
MarketsandMarkets

Over the years, the molecular spectroscopy market, comprising instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of molecular spectroscopy applications.
Multi-Channel Pipettor QC Trends 2014
HTStec

Multi-channel pipettors are essential tools in most life science laboratories today. Yet the impact of undertaking quality control (QC) measures on improving data quality, enhancing productivity/efficiency and reducing experimental failures has only relatively recently been recognized. Understanding how lab users approach the issue of pipettor QC is important as the industry struggles to adopt standards for automated pipetting.
Biomarkers Market 2013 - 2020
Allied Market Research

Disease diagnostic application remains the key area of application that is expected to reach 6.1 $billion in 2020. However, application of diagnostic biomarkers in forensics and molecular diagnostics is catching up quite significantly. Molecular diagnostics is expected to grow at a CAGR of 17.6% from 2013 to 2020.
DNA Sequencing
RI Technologies

This report presents an in depth analysis of DNA sequencing market. The study emphasizes on both, the methods and instruments/software of DNA sequencing in medical research, agriculture and animal husbandry and DNA testing and forensics application areas.
Blood - Components, Testing & Collection
RI Technologies

This market insight report gives an insight into global blood ? components, testing and collection market. The report also provides market analytics by Product Type.
Bionanotechnology
RI Technologies

This report on Bionanotechnology studies the impact of nanotechnology in various biotechnology applications. The study focuses on major applications including food, drug discovery and development, diagnostic tools and devices, and other (bionanosensors).
Multi-Mode Microplate Reader Trends 2013
HTStec

This market report summarizes the results of HTStec’s 4th industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2013.
Scientific News
Alzheimer's Disease Linked To Heart's Effect On The Brain
Theory suggests that Alzheimer’s Disease has its origin in the heart and vascular system.
On Time, On Target
A novel tool could help personalize cancer treatments.
Single-Cell, 42-plexed Protein Analysis Achieved with a New Microchip Technology
A novel microdevice capable of detecting 42 unique immune effector proteins has been developed.
Ground-Breaking Lung Cancer Breath Test In Clinical Trial
University of Leicester and Leicester’s Hospitals to evaluate revolutionary device which detects lung cancer in early stages.
Saliva Test to Diagnose Autism
A spit test may one day be able to diagnose autism according to researchers at Clarkson University and the State University of New York at Plattsburgh.
Paper Test for Ebola
Prototype is designed to detect diseases and deliver real-time epidemiological data.
New €25 Blood Test A Breakthrough In The Diagnosis Of Bowel Cancer
New blood test will spot bowel cancer at earliest stage, removing the need for ‘unpleasant’ faecal screens.
New Biomarkers To Spot Pancreatic Cancer Early
A combination of two biomarkers can identify pre-clinical pancreatic cancer.
NIH Launches Tool to Advance Down Syndrome Research
Web portal will help approved professionals to plan clinical studies.
New Blood Test For Aggressive Bone Cancer
Researchers at the University of East Anglia are developing a simple blood test to diagnose bone cancer thanks to funding from the Big C.
Business News
Seven Of The Most Promising New Technologies Developed In UK Universities
The Royal Academy of Engineering’s Enterprise Hub has identified seven of the most promising inventors based in UK universities and is supporting them to turn their research into spin-out companies.
Aptose to Host Quarter and Seven Month Transition Period Ended December 31, 2014
Company intends to host a conference call on the same day.
QIAGEN Collaborates with Allele Frequency Community
QIAGEN providing secure bioinformatics infrastructure and software for research and clinical labs to contribute and gain insights from Allele Frequency Community.
Quest Diagnostics Named "Most Admired Company"
Company earns Fortune Magazine 2015 "World's Most Admired Companies" designation by Fortune Magazine.
MRIGlobal Wins Contract to Develop Whole Genome Sequencing Diagnostic System
Sample-to-Sequence system has potential to revolutionize clinical diagnostics.
NICE Publishes Medtech Innovation Briefing on ZedScan
MIB to provide objective information on device and diagnostic technologies to aid local decision-making.
Duke Awarded $10.4 Million Contract To Continue Developing Radiation Test
The blood test will be able to tell in hours how much radiation a person has absorbed from a nuclear incident.
Aptose to Present at the RBC Capital Markets 2015 Global Healthcare Conference
Dr. Rice will provide a corporate overview of the Company's recent activities and strategic direction.
Collaboration with MD Anderson Cancer Center on Colorectal Cancer
Collaboration to investigate the clinical use of ANGLE’s Parsortix system.
Dako; ONO Pharmaceutical Collaborate
Collaboration is for development of PD-L1 companion diagnostic test for investigational cancer drug Opdivo® (Nivolumab).

Events
Microarray Technology
17 Mar 2015
Microarray Technology ...
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Biodetection & Biosensors
17 Mar 2015
Biodetection & Biosensors ...
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Point-of-Care Diagnostics
17 Mar 2015
Point-of-Care Diagnostics ...
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Medical Device and Diagnostics
17 Mar 2015
Medical Device and Diagnostics ...
More information

ePosters
Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications
*Robert-Bosch-GmbH - Robert-Bosch-Platz 1, 70839 Gerlingen-Schillerhöhe, Germany. **University of Freiburg, Department of Microsystems Engineering - IMTEK, 79110 Freiburg, Germany

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.
A multiplexed amplicon sequencing technology for FFPE and circulating, cell-free DNA
Swift Biosceinces

A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.
Validation of Collection and Extraction Methods of Saliva for Use in Biomarker Research
Department of Pharmaceutical Sciences, South College School of Pharmacy, Knoxville, TN 37922

This poster investigates the collection and extraction methods of saliva for use in biomarker research.
Rapid Detection of Somatic Mutations in Cancer Genes
DiaCarta, Inc.

Rapid higly sensitive detection of tumor gene mutations in DNA derived from FFPE or plasma samples can be achieved with QClamp PCR technology.
New Microarray Slides Capable of Enhancing Fluorescence
Plasmonix, Inc., Gaithersburg, MD, USA

Slides for proteomic microarrays with imbedded nanoparticles that enhance fluoresce by ~ 30-fold via a plasmonic effect. These slides are useful for enhancing fluorescence of protein or peptide microarrays.
Expression of Wnt5a in Urothelial Carcinoma as a Potential Prognostic Marker
1. OMSII; 2. Specialty Medicine; 3. Biomedical Sciences, HCOM

Our results support the previous studies that suggest Wnt5a plays a pathological role in urothelial carcinoma.
Expression Profiling of Circulating Tumor Cells: a Prognostic and Predictive Biomarker in Cancer.
Bauer4.1TATAA Biocenter, Göteborg, Sweden (www.tataa.com); 2Inst. of Biotechnology, CAS, Czech Republic; 3AdnaGen GmbH, Ostpassage7, D-30853 Langenhagen, Germany (www.adnagen.com); 4Dep of Gynecoland

We show non-responders to treatment among breast cancer patients can be identified by expression profiling of circulating tumor cells
"In-vitro studies on hydroxamic acid- CT DNA binding"
Research Scholar

In vitro studies of five the interaction between five different derivatives of hydroxamic acids, N-phenyl 2,4dichloro phenoxybutyro, N-m-tolyl 2,4 dichlorophenoxyglutero, N-m-tolyl-4-chlorophenoxyaceto, N-m-chloro-phenyl-tertiarybutylbenzo and N-p-tolyl-iso-valero hydroxamic acids and calf thymus DNA was investigated under simulated physiological condition.
Recent Technical Developments in the Standardized Separation and Measurement of Extracellular Vesicles
(1) Izon Science US Ltd, Christchurch, New Zealand (2) The University of Queensland, Brisbane, QLD, Australia

We present robust and practical solutions for the standardization of EV isolation and concentration measurement. EV concentration also needs to have a defined size range. With these solutions, significant improvement in the reproducibility and comparability of results between different researchers is possible.
High Titre BacMam viruses improve transduction efficiency of mammalian cells
Oxford Expression Technologies Ltd, Oxford Brookes University

We present a method for producing high titre BacMam virus vectors for the efficient transduction of mammalian cells.
Application Notes
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Automated sample preparation for the determination of testosterone in serum by LC-MSMS
Tecan Group Ltd.

For accurate, reproducible quantification of testosterone, a growing number of laboratories are shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry. This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.
Validating the Expression Consistency of a Housekeeping Protein
Bio-Rad Laboratories

Housekeeping proteins (HKP) are typically used as loading controls because it is assumed that the HKP expression level remains consistent across samples. However, there is evidence that HKP expression levels change in many scenarios, including siRNA treatment, cell death, cell differentiation, etc.
A Method for Greater Reliability in Western Blot Loading Controls: Stain-Free Total Protein Quantitation
Bio-Rad Laboratories

Reliable assessment of changes in target protein levels by western blot requires measurement of both the target and loading control proteins in the linear dynamic range. Stain-free technology is a novel method introduced by Bio-Rad to visualize and quantify proteins in gels and blots.
General V3 Western Blotting Protocol
Bio-Rad Laboratories

Western blotting is a very useful and widely adopted lab technique, but the traditional procedure can be long and tedious. Researchers can assess only whether a blot image is captured at the end of the long procedure and the quality of western blot data is sometimes challenged due to poor loading controls.
Determining the Appropriate Sample Load When Using a Stain-Free V3 Western Workflow™
Bio-Rad Laboratories

Traditional western blot workflows require an appropriate sample load to detect both target proteins and loading control proteins. The discrepancy between these quantities often leads to oversaturated protein bands, forcing researchers to sometimes run two duplicate gels or titrate down the antibody concentration in order to get quantitative results.
Determining the Appropriate Film Exposure Time
Bio-Rad Laboratories

Film has a limited linear dynamic range for light detection and is often easily saturated by the chemiluminescent signals from the blot.
Determining the Appropriate Sample Load for Western Blots
Bio-Rad Laboratories

Reliable western blot data can be generated only when the proper sample amount of protein is used. Loading too much protein leads to signal saturation in western blots, yet too little produces weak signals.
Avoiding Housekeeping Protein Detection Saturation
Bio-Rad Laboratories

Reliable western blot data require detection of the target and loading control proteins in the linear dynamic range. Many published western blot images show saturated protein bands, indicating that they were not measured in the linear dynamic range. Quantitative analysis based on this type of data is not reliable.
Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton

In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
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