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Webcasts
Webcasts - Solutions Beyond Water - Successfully pipetting problematic liquidsSolutions Beyond Water - Successfully pipetting problematic liquids
Join us to learn how to best handle problematic liquids.
Webcasts - How to optimize sample preparation step prior to extractionHow to optimize sample preparation step prior to extraction
In this free to attend On Demand webcast presented by Stephane Karoubi, Product Manager, and Sophie Dubacq, Application Engineer, from Bertin Technologies.

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Multi-Channel Pipettor QC Trends 2014
HTStec

Multi-channel pipettors are essential tools in most life science laboratories today. Yet the impact of undertaking quality control (QC) measures on improving data quality, enhancing productivity/efficiency and reducing experimental failures has only relatively recently been recognized. Understanding how lab users approach the issue of pipettor QC is important as the industry struggles to adopt standards for automated pipetting.
Companion Diagnostics and Personalized Medicine
Select Biosciences Ltd

This is the latest and most up-to-date Market Report from Select Biosciences addressing the companion diagnostics (CDx) and personalized medicine marketplace. Personalized medicine is a broad field with several stakeholders all of which must be aligned in order to capture the immense potential value in targeting therapeutics to the correct patient population—the field of stratified medicine.
Molecular Diagnostics: Market Landscape
Datamonitor plc

This report analyzes the emerging sector of molecular diagnostics. It provides a clear classification, assessing the leading technologies and key tests that are positioned in this exciting area of diagnostics. The current MDx market size and leading players are analyzed, with a market forecast of the MDx segment as well as the total in vitro diagnostic market over 2010-16 provided.
Innovations in Combating Infectious Diseases: Opportunities in therapeutics and diagnostics through application of proteomics, genomics, nanotechnology, and novel sources of lead generation
Business Insights

This report makes a detailed and comprehensive analysis of the cutting edge of research aiming to reveal how bacteria, viruses, fungi, and prions infect and affect their hosts. It also assesses the new technologies and techniques that are being used to design and develop the anti-infective drugs and diagnostic methods of the 21st century.
The Future of Molecular Diagnostics: Innovative technologies driving market opportunities in personalized medicine
Business Insights

This report analyzes the current and potential world markets for molecular diagnostics, including advances in the field. This report generally forecasts future growth to 2015. The report breaks down market forecasts by type of test and by geography. It indicates which companies have key products in the market place. It also analyzes key drivers of this market.
Multiplexed Diagnostics 2010
Select Biosciences Ltd

The multiplexed diagnostics market has grown rapidly and generated sales of approximately $2.4 billon in 2009, but is now balanced on multiple tipping points.
Genomics, Proteomics and Metabolomics in Diagnostics: Market landscape, innovative technologies and future outlook
Business Insights

There has been a significant transition in the diagnostic techniques created with increasing technological innovations. In the future, the focus will be on genetic study and disease predisposition, which will test patients' probability of acquiring a disease or a disorder, enabling precautionary steps.
Scientific News
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Magnetic Nanoparticles May Reveal Early Traces Of Cancer
Rice University students’ computer program aids MD Anderson diagnostic initiative .
New Blood Test for The Earlier Diagnosis of Breast Cancer Spread
Researchers at University of Westminster have confirmed that a new blood test can detect if breast cancer has spread to other parts of the body.
Genetic Approach May Lead to New Treatments for Digestive Diseases
Researchers at UMass Medical School have identified a new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system.
Biomarkers for Profiling Prostate Cancer Patients
Exiqon A/S has announced the publication of validation of prognostic microRNA biomarkers for the aggressiveness of prostate cancer in independent cohorts.
World-First Blood Test For Parkinson's
La Trobe University researchers have developed a world-first diagnostic blood test which could change the lives of people with Parkinson's disease.
Parsortix Demonstrates Benefits Over Marker-Based Systems
Research published online in the International Journal of Cancer, shows the ParsortixTM System efficiently captures and harvests intact, viable circulating tumour cells (CTCs), including EpCAM-negative CTCs, to allow for broader downstream CTC analysis.
Hepatitis C Virus Testing Guidelines Miss Too Many Cases
Urban emergency departments a good place to enact universal screening for adults.
NIH Sequences Genome of a Fungus
Researchers at the Institute have sequenced genome of human, mouse and rat Pneumocystis that cause life-threatening Pneumonia in immunosuppressed hosts.
Business News
Fluxion Biosciences, UT Health Collaborate
Company has announced collaboration with UT Health to develop novel liquid biopsy approaches to improve the ability to diagnose, monitor, and treat cancer patients.
Zika Test from Quest Diagnostics Authorized by the FDA
Company has announced that it has received a U.S. FDA emergency use authorization for the Zika Virus RT-PCR test.
Liquid Biotech USA, MolecularMatch Partner
Company has announced partnership with Liquid Biotech to expedite cancer detection and treatment.
twoXAR, Stanford University Announce Collaboration
Collaboration aims to support research focused on the identification of drug candidates targeting rare disorders such as lymphatic malformation and EBS.
Galapagos, Abbvie Expand Cystic Fibrosis Collaboration
Company has announced that it has expand cystic fibrosis collaboration with Abbvie to reflect the successful expansion of their CF portfolio.
PerkinElmer Sells NTD to Eurofins
PerkinElmer has announced that it sold its U. S. prenatal screening laboratory services business PerkinElmer Labs/NTD ("NTD") to Eurofins Scientific.
Novacyt raises €7.75m to complete the acquisition of Primerdesign
The acquisition should complete by 12th May 2016.
Cepheid Announces Partnership with Medline
Company has announced partnership with Medline for the distribution of the GeneXpert® System.
Interpace Diagnostics Announces New Coding by Novitas Solutions
Company has announced that its MAC, Novitas Solutions, has assigned a new molecular CPT code to its PancraGen™ test for pancreatic cysts.
Investment in MBLI Expands JSR Life Sciences
JSR Micro has announced that it has expanded the JSR Life Sciences business division by becoming the majority shareholder of Boston area-based MBL International Corporation (MBLI).

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ISEV Annual Meeting 2016
04 May 2016
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09 May 2016
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The Controlling Cancer Summit
17 May 2016
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ePosters
Clinical Applications of “Liquid biopsy” in the Colorectal Cancer Treatmen
Saitama Medical Center, Jichi Medical University, Saitama. Japan

Liquid biopsy provides a circulating biomarker not only for treatment response but decision making of a sequential strategy.
Finite element modelling for the optimization of temperature control in Lab-on-a-Chip devices
(a) Thomas Johann Seebeck Department of Electronics, Tallinn University of Technology, Tallinn, Estonia; (b) SelfDiagnostics Deutschland GmbH, Leipzig, Germany

The presented finite element model aims to help in the development of Lab-on-a-Chip devices which require temperature control. The model simulates the thermal system in such devices to enable in silico validation of designs and geometry optimization, and aims to be a versatile tool supporting multiple temperature control methods.
Development of an Integrated Paper-based Molecular Diagnostic Platform
Brunel University, Kingston Lane, Uxbridge, United Kingdom, UB8 3PH

The poster describes a modular development of a paper-based molecular diagnostic device and the latest results obtained from a proof-of-concept device.
Differences in the Neurophysiology of Infants with Down Syndrome May Predict Protective/Risk Markers for Subsequent Alzheimer’s Disease
1Birkbeck Centre for Brain & Cognitive Development, University of London 2LondDownS Consortium

Our work set out to understand early individual differences in memory abilities of infants with DS that may be predictive of subsequent cognitive phenotypes of AD.
The Challenges of Genetic Testing in Patients Diagnosed with Breast Cancer; The Kent Oncology Centre Experience
1 Kent Oncology Center, Maidstone and Tunbridge Wells Hospital, Maidstone, ME16 9QQ 2 Institute of Cancer Research, 123 Old Brompton Rd, London SW7 3RP

In this study we explore retrospective data to determine strategies for optimizing the genetic referral pathways for breast cancer.
Translational Research of oral Neural Crest-Derived Stem Cells (oNCSCs) in Regenerative Dentistry
1Stavropol State Medical University, Russian Federation, 2Praxisteam Hasslinghausen, Germany, 3Implantology Center Kassel, Germany, 4Witten/ Herdecke University, Germany, 5University of Reading, UK, 6

In this review poster, we summarize current knowledge on the oral neural crest-derived stem cell populations (oNCSCs) and discuss their potential in regenerative periodontology as a part of regenerative dentistry.
Development of a nucleic acid-based amplification test as point-of-care rapid test detecting sexually-transmitted diseases for home-care
Fraunhofer Institute of Cell Therapy and Immunology Leipzig, Nanotechnology Unit, D-04103 Leipzig; University of Leipzig, Institute of Analytical Chemistry, Working Group Prof. Belder, D-04103 Leipzig

The main problem of early diagnosis of STI is the lack of suitable systems. Therefore a quick home test is needed. In this poster, a microfluidic cartridge combining an isothermal amplification with detection on a lateral flow strip is presented.
A Microwave/Microfluidics Integrated Label-Free Detection and Content Sensing System for Point-of-Care Applications
University of Waterloo

This poster presents a droplet-based microfluidic device integrated with a microwave wave sensor, which is also a heater, for simultaneous sensing and heating of individual nanoliter-sized droplets.
LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Agilent Technologies, Diagnostics and Genomics Group

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.
Alterations in serum thrombotic biomarker in patients with acute myocardial infarction
Dept of Biochemistry, Collage of Science, King Saud University, POB 2455, Riyadh 11451, Saudi Arabia

A combination of these biomarkers could serve as a useful biomarker tool to assess the prognosis of AMI. (This study was supported by National Plan for Science and Technology Program by King Saud University Project Number 08-BIO571-02).
Application Notes
Microbial Detection and Quantification Using the IntelliQube® from Douglas Scientific®
Douglas Scientific

Nucleic Acid Testing (NAT) is a powerful tool for the quantification of microorganisms and are used in many fields. In this study commercially available microbial NAT kits were successfully miniaturized from 20 µL to 1.6 µL reaction volumes using the IntelliQube. The IntelliQube delivers efficient and economical high throughput sample processing for microbial qPCR applications.
Evaluation of a New Accurate, Automated and Cost-effective Approach for the Analysis of Pharmacologically Important Copy Number Variation
Douglas Scientific

The IntelliQube® from Douglas Scientific® is designed to address the need for accurate and reliable results for studies such as CNV determination.
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Automated sample preparation for the determination of testosterone in serum by LC-MSMS
Tecan Group Ltd.

For accurate, reproducible quantification of testosterone, a growing number of laboratories are shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry. This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.
Validating the Expression Consistency of a Housekeeping Protein
Bio-Rad Laboratories

Housekeeping proteins (HKP) are typically used as loading controls because it is assumed that the HKP expression level remains consistent across samples. However, there is evidence that HKP expression levels change in many scenarios, including siRNA treatment, cell death, cell differentiation, etc.
A Method for Greater Reliability in Western Blot Loading Controls: Stain-Free Total Protein Quantitation
Bio-Rad Laboratories

Reliable assessment of changes in target protein levels by western blot requires measurement of both the target and loading control proteins in the linear dynamic range. Stain-free technology is a novel method introduced by Bio-Rad to visualize and quantify proteins in gels and blots.
General V3 Western Blotting Protocol
Bio-Rad Laboratories

Western blotting is a very useful and widely adopted lab technique, but the traditional procedure can be long and tedious. Researchers can assess only whether a blot image is captured at the end of the long procedure and the quality of western blot data is sometimes challenged due to poor loading controls.
Determining the Appropriate Sample Load When Using a Stain-Free V3 Western Workflow™
Bio-Rad Laboratories

Traditional western blot workflows require an appropriate sample load to detect both target proteins and loading control proteins. The discrepancy between these quantities often leads to oversaturated protein bands, forcing researchers to sometimes run two duplicate gels or titrate down the antibody concentration in order to get quantitative results.
Determining the Appropriate Film Exposure Time
Bio-Rad Laboratories

Film has a limited linear dynamic range for light detection and is often easily saturated by the chemiluminescent signals from the blot.
Determining the Appropriate Sample Load for Western Blots
Bio-Rad Laboratories

Reliable western blot data can be generated only when the proper sample amount of protein is used. Loading too much protein leads to signal saturation in western blots, yet too little produces weak signals.
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