Corporate Banner
Satellite Banner
Molecular & Clinical Diagnostics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

EnviroLogix™ Signs Collaborative Agreement with Douglas Scientific™

Published: Tuesday, July 24, 2012
Last Updated: Tuesday, July 24, 2012
Bookmark and Share
The agreement will see the companies develop and optimize solutions for high throughput real time and endpoint nucleic acid analysis.

The companies will leverage and build upon EnviroLogix’ revolutionary isothermal DNAble®v2.0 chemistry and Douglas Scientific’s disruptive Array Tape™ Platform.

The DNAble isothermal amplification and detection technology represents a new paradigm in real time nucleic acid analysis and has the potential to impact the world of molecular biology. This new DNAble assay solution developed by EnviroLogix delivers results equivalent to qPCR in less than 10 minutes with the demonstrated ability to utilize crude sample preparations. These attributes make this solution equally valuable for point-of-use testing as well as extremely high throughput applications.

“The substantial improvement in throughput with DNAble alone is significant, but when combined with the Douglas Scientific Array Tape solutions it becomes revolutionary,” said Dan Malmstrom, President and COO of Douglas Scientific. “By partnering with EnviroLogix, we can provide end-to-end qualitative and quantitative nucleic acid testing automation solutions that break the current paradigms of qPCR.”

DNAble is a very rapid, highly specific isothermal nucleic acid amplification technology that can amplify both RNA and DNA targets with single base resolution a billion-fold in 5-10 minutes at a single and constant temperature.  It features EnviroLogix’ next generation DNAble, v2.0 chemistry.  The proprietary chemistry produces highly specific, rapid, multiplexed, quantitative results rivaling qPCR.  Unlike PCR, DNAble can amplify a target sequence from a crude sample preparation and do so with minimal equipment. DNAble’s unique amplification process begins with a nicking enzyme that nicks the DNA structure at specific recognition sites.  A polymerase then extends from the “nicked” site displacing the original opened single strand.  These single strands hybridize with both the forward and reverse DNAble templates and the reaction begins to occur at an exponential rate yielding a detectable target in less than 10 minutes.

“We are delighted to be associated with a fast-paced, growing organization like Douglas Scientific, and believe that this will be a winning combination of chemistry and engineering” said Bruce Ferguson, President and CEO of EnviroLogix. “PCR was once a fledgling technology and now is the gold standard. That is how we view DNAble. Combined with the power of Douglas Scientific’s automated high throughput equipment, DNAble brings a game-changing technological breakthrough in real time quantitative molecular diagnostics.”

Array Tape™ is a continuous polymer strip, serially embossed with reaction wells in customized volumes and formats. With miniaturized reaction wells, this thin (0.3 mm) and flexible solution allows 200 microplate equivalents (76,800 reaction wells) to be spooled onto a single, compact reel. It is an automated, adaptable microplate replacement for high throughput screening.

Douglas Scientific provides inline, modular instrumentation that is fully integrated and optimized for use with Array Tape™ including Nexar® liquid handling and assay processing system, Soellex® thermal cycler, Araya® fluorescent detection instrumentation and software solutions. The platform enables a continuous reel-to-reel process flow to maximize throughput and reduce costs.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Douglas Scientific, LGC Distribution Agreement
Companies have formalized an exclusive distribution agreement for the sale of Douglas Scientific’s innovative Array Tape® Platform.
Monday, August 11, 2014
Scientific News
AACC 2016 Sees Clinical Chemistry Labs Drive Precision Medicine Offerings
Biomarker assays to enable precision medicine and risk assessment, mass spec-based tests designed for use in clinical labs large and small, and liquid biopsy technology captured the spotlight at the AACC annual meeting.
Diagnosing Bacterial Infections in Blood Samples
Researchers have diagnosed a bacterial infection from a blood sample in infants.
Neurodvelopmental Disorder Cause Linked to SON Gene
A genetic link has been discovered for a previously unxplained neurodevelopmental disorder.
World's Most In-Depth Study to Detect Alzheimer's Disease
A multisite team will see the most thorough and vigorous testing for Alzheimer's ever performed on volunteers.
Personalised Medicine: Dose by Design
Personalised medicine holds the promise of a new approach to healthcare, tailored exactly to our individual needs, as Congenica's Nick Lench discussed on a recent BBC Radio 4 programme.
Misdiagnosis in HCM Tests
Genetic tests for potentially fatal heart anomaly can misdiagnose condition in black Americans.
Computers Better Predict Lung Cancer Type, Severity
Study shows automating the analysis of cancer tissue samples increases the accuracy of tumor classification and patient prognoses.
Examining New Hypotheses for Undiagnosed Patients
UnDx Consortium gathers in San Diego to create new paths to identifying currently undiagnosed illnesses.
Automating Genetic Analysis
Researchers are looking to have computers help perform genetic analysis when scientists study a patient's genome to diagnose a disease.
Understanding Tumor Evolution
Study provides insight into tumor evolution; may point to improved diagnosis and treatment.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!