Corporate Banner
Satellite Banner
Molecular & Clinical Diagnostics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

New Cyanine Dyes Reduce Time and Cost of Oligo Labelling

Published: Monday, March 25, 2013
Last Updated: Sunday, March 24, 2013
Bookmark and Share
Link Technologies’ solid-supported Cyanine 540 and 650 dyes increase workflow efficiency.

Link Technologies Ltd has launched a range of high quality cyanine dye products to support the continued increase in demand for fluorescent labelling in biological imaging and molecular diagnostics.

As well as introducing a new range of 3’-CPG solid supports modified with Cyanine 540 and Cyanine 650, Link Technologies now also manufactures and supplies the commonly used phosphoramidites, so researchers can now source an extended range of cyanine reagents produced to Link Technologies’ exacting standards.

Until now, 3’-cyanine modification of an oligonucleotide could only be done post-synthetically, normally to an amino-modified oligo, or by the use of a cyanine phosphoramidite onto a universal or modified support that will not interfere with the intended use of the oligo.

With Link Technologies’ innovative 3’-modified 1000Å CPG supports, customers can add cyanine dyes directly to their oligos of interest without any additional modification step.

Link Technologies’ cyanine dye supports therefore save time by reducing the number of experimental steps and avoid the unnecessary cost of amino-modified oligos or the inconvenience of combining cyanine phosphoramidites and universal supports.

Used as fluorescent markers in oligonucleotide synthesis, dyes are central to numerous detection techniques, such as probes for monitoring real-time PCR, fluorescence in situ hybridization, SERRS-based DNA detection assays and FRET studies in general (e.g. DNA-protein interaction studies).

3’-Labelling is particularly useful in the latter where the FRET partner is incorporated either at the 5’-end or within the oligonucleotide sequence.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

LINK Strengthens Presence in Switzerland
Link Technologies appoints Swiss company as first partner in Europe.
Tuesday, September 08, 2015
LINK Strengthens Presence in Switzerland with Distribution Agreement
Link Technologies appoints Swiss company Chemie Brunschwig AG as first partner in Europe.
Friday, September 04, 2015
LINK Strengthens Presence in Japan with New Distribution Agreements
Link Technologies appoints Cosmo Bio and Shigematsu to work alongside Gene Design.
Tuesday, June 30, 2015
Scientific News
Some Women With PCOS May Have Adrenal Disorder
Researchers at NIH have found that a subgroup of women with PCOS, a leading cause of infertility, may produce excess adrenal hormones.
Faster Detection of Pathogens in the Lungs
Thanks to new molecular-based methods, mycobacterial pathogens that cause pulmonary infections or tuberculosis can now be detected much more quickly.
Proteins in Blood of Heart Disease Patients May Predict Adverse Events
Nine-protein test shown superior to conventional assessments of risk.
£14m EU Project To Aid Meningitis Diagnosis and Cut Antibiotic Use
An international team of doctors are aiming to develop a rapid test to allow medics to quickly identify bacterial infection in children.
Bringing AFM to Medical Diagnostics
Company has announced that its NanoWizard® AFM and ForceRobot® systems are being used in the field of medical diagnostics in the Supersensitive Molecular Layer Laboratory of POSTECH in Korea.
Scientific Gains May Make Electronic Nose the Next Everyday Device
UT Dallas team breathes new life into possibilities by using CMOS integrated circuits technology.
Electronic Sensor Tells Dead Bacteria From Live
The sensor, which measures 'osmoregulation', is a potential future tool for medicine and food safety.
Diagnosing Systemic Infections Quickly, Reliably
Team develop rapid and specific diagnostic assay that could help physicians decide within an hour whether a patient has a systemic infection and should be hospitalized for aggressive intervention therapy.
A Future Tool for Medicine, Food Safety
A new type of electronic sensor that might be used to quickly detect and classify bacteria for medical diagnostics and food safety has passed a key hurdle by distinguishing between dead and living bacteria cells.
Genome Sequencing Helps Determine End of TB Outbreak
Using genome sequencing, researchers from the University of British Columbia, along with colleagues at the Imperial College in London, now have the ability to determine when a tuberculosis (TB) outbreak is over.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!