Corporate Banner
Satellite Banner
Molecular & Clinical Diagnostics
Scientific Community
Become a Member | Sign in
Home>News>This Article

Fluxion Delivers First Commercial Shipments of IsoFlux™ System

Published: Friday, June 07, 2013
Last Updated: Friday, June 07, 2013
Bookmark and Share
Platform enables pharma, research, and diagnostic companies to utilize blood samples for cancer diagnostic breakthroughs.

Fluxion Biosciences, Inc. has announced that the first round of IsoFlux instruments has been delivered to customers around the world.

Initially announced in November, the IsoFlux System is an automated instrument and microfluidic cartridge for high sensitivity enrichment of rare cells such as circulating tumor cells (CTCs), stem cells, and immune cells.

The first 15 instrument placements included global pharma companies, emerging biotechs, and leading cancer research institutes.

"We're very pleased that after two years of research and development, the IsoFlux System is now in the hands of very capable customers," said Jeff Jensen, CEO of Fluxion.

Jensen continued, "We fully expect that the next wave of breakthroughs in cancer diagnostics will come from this group and future customers."

CTCs are cells that disseminate from primary tumors and contribute to the spread of the disease to other parts of the body.

They circulate in very low concentration in the peripheral blood and are not readily retrievable with conventional technologies.

The IsoFlux System recovers these rare tumor cells from a standard blood draw and prepares them for molecular analysis.

The platform offers improved sensitivity of CTC recovery in a low-volume format optimized for analytical platforms such as real-time quantitative PCR (qPCR), next generation sequencing (NGS), and immunofluorescence.

Initial customers have adopted the system to characterize CTCs for biomarkers including gene expression, mutations, and chromosomal aberrations.

“Our reconnaissance identified the IsoFlux instrument as a perfectly suitable technology platform for our needs in translational cancer research to analyze circulating tumor cells from patients with various cancer indications” said Dr. Norbert Kienzle at the Ingham Institute for Applied Medical Research in Sydney, Australia.

Dr. Kienzle continued, “In addition to highly sensitive recovery of CTCs and ease of system use, we need flexibility for downstream molecular and cellular analyses - the IsoFlux ticks all these boxes. Our initial hands-on experience and the constructive working relationship with Fluxion gives us confidence to go forward with our research questions on the biology and clinical utility of CTCs, ultimately aiming to improve patient outcomes in one of Sydney’s largest and fastest growing cancer populations.”

The IsoFlux System is sold globally through Fluxion in North America and a network of distributors in Europe and Asia.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Detecting HIV Diagnostic Antibodies with DNA Nanomachines
New research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and auto-immune diseases such as rheumatoid arthritis and HIV.
Horse Illness Shares Signs of Human Disease
Horses with a rare nerve condition have similar signs of disease as people with conditions such as Alzheimer’s, a study has found.
Compound Doubles Up On Cancer Detection
Researchers have found that tagging a pair of markers found almost exclusively on a common brain cancer yields a cancer signal that is both more obvious and more specific to cancer.
The Age of Humans Controlling Microbes
Engineered bacteria could soon be used to detect environmental toxins, treat diseases, and sustainably produce chemicals and fuels.
Predictive Model for Breast Cancer Progression
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
Are Changes to Current Colorectal Cancer Screening Guidelines Required?
Editorial suggests more research is needed to pinpoint age to end aggressive screening.
New Molecular Marker for Killer Cells
Cell marker enables prognosis about the course of infections.
Sniffing Out Cancer
Scientists have been exploring new ways to “smell” signs of cancer by analyzing what’s in patients’ breath.
New Test Detects All Viruses
A new test detects virtually any virus that infects people and animals, according to research at Washington University School of Medicine in St. Louis, where the technology was developed.
Scientists Create World’s Largest Catalog of Human Genomic Variation
An international team of scientists from the 1000 Genomes Project Consortium has created the world’s largest catalog of genomic differences among humans, providing researchers with powerful clues to help them establish why some people are susceptible to various diseases.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos