Corporate Banner
Satellite Banner
Molecular & Clinical Diagnostics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Mayo Clinic, Whole Biome Announce Collaboration

Published: Tuesday, May 20, 2014
Last Updated: Thursday, May 22, 2014
Bookmark and Share
Joint development of microbiome diagnostic testing to focus on women’s health and preterm labor.

Certain strains of the campylobacter bacteria, seen above, have long been implicated in preterm labor and spontaneous abortion in livestock. Scientific evidence has started mounting that this foodborne pathogen may trigger preterm labor in humans, as well. New tests from the Mayo Clinic-Whole Biome collaboration aim to detect a range of bacteria, such as campylobacter, to help expectant mothers achieve full-term pregnancies.

The Mayo Clinic Center for Individualized Medicine and Whole Biome today announced a collaboration to develop microbiome targeted diagnostic testing, beginning in Women’s Health, with a focus on preterm labor. Preterm birth is the most common cause of infant death and is the leading cause of long-term disability in children, according to the National Institutes of Health. Many preterm births may be delayed or prevented with microbiome-based testing and intervention, according to Mayo Clinic experts.

“Understanding the microbiome, and translating that understanding into enhanced patient care is a major goal within the Center for Individualized Medicine,” says Heidi Nelson, M.D., director of the center’s Microbiome Program. “Our early work suggests the microbiome may play a significant role in triggering preterm labor, and we are excited to take these early results into clinical trials with Whole Biome’s analytics platform.”

“This collaboration is bringing together the clinical expertise of Mayo Clinic with our innovative diagnostic tools,” says Colleen Cutcliffe, CEO of Whole Biome. “Together, we plan to transform affordable and detailed microbiome information into tools that will improve patient health and their lives.”

Whole Biome’s Complete Biome Test is able to generate microbiome profiles with strain-level resolution at a low cost, enabling researchers and physicians to more rapidly conduct large-scale studies and produce effective microbiome diagnostics to help predict, treat and prevent life-threatening issues.

The microbiome is defined as all of the microbes that reside on the inside and outside of each individual. A person’s body contains 10-times more microbial cells than human cells. Humans have co-evolved with microbiomes and house many microbes that are beneficial for health. However, the human race has been systematically depleting these “good” microbes in an attempt to eradicate the harmful ones through use of antibiotics, antibacterial processes and prolific antimicrobial consumer products. For decades, researchers have known that the microbiome represents a wealth of opportunity in shaping health, but only recently have the genomic and analysis tools been available to make this a reality.

The Center for Individualized Medicine is collaborating with Whole Biome to accelerate the development of novel diagnostics that characterize the microbiome. Whole Biome utilizes sample preparation techniques and specialized analytics that integrate high throughput and long read-length DNA sequencing data to generate high-accuracy microbiome profiles that enable the identification of relevant changes.

The initial focus will be in Women’s Health. Unbalanced vaginal microbiomes have been implicated in a variety of medical issues, including yeast infections, bacterial vaginosis and preterm labor. The collaboration’s goal will be to develop a microbiome-based diagnostic test for early indication of preterm labor.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Mayo Clinic Forms Joint Venture with Cancer Genetics
OncoSpire Genomics will seek to discover and commercialize biomarkers for multiple cancer types.
Thursday, May 23, 2013
Saliva Gland Test for Parkinson's Shows Promise
Findings described as a "big step forward" for research and treatment of Parkinson's disease.
Wednesday, January 16, 2013
Men with Fibromyalgia Often Go Undiagnosed, Mayo Clinic Study Suggests
There is not yet a diagnostic test to establish that someone has fibromyalgia, there is no cure and many symptoms can overlap with or get mistaken for other conditions.
Friday, December 21, 2012
Scientific News
‘Mutation-Tracking’ Blood Test for Breast Cancer
Scientists have developed a blood test for breast cancer able to identify which patients will suffer a relapse after treatment, months before tumours are visible on hospital scans.
Common ‘Heart Attack’ Blood Test May Predict Future Hypertension
Small rises in troponin levels may have value as markers for subclinical heart damage and high blood pressure.
Poor Survival Rates in Leukemia Linked to Persistent Genetic Mutations
For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival.
'Fountain of Youth' Protein Points to Possible Human Health Benefit
Patients with higher blood levels of growth factor have lower risk of cardiovascular problems.
Signature of Microbiomes Linked to Schizophrenia
Studying microbiomes in throat may help identify causes and treatments of brain disorder.
Imaging Software Could Speed Breast Cancer Diagnosis
Technology could improve access to diagnostic services in developing countries.
The Changing Tides of the In Vitro Diagnostics Market
With the increasing focus in personalized medicine, diagnostics plays a crucial role in patient monitoring.
Data Mining DNA For Polycystic Ovary Syndrome Genes
A new Northwestern Medicine genome-wide association study of PCOS – the first of its kind to focus on women of European ancestry – has provided important new insights into the underlying biology of the disorder.
Algorithm Interprets Breathing Difficulties to Aid in Medical Care
Researchers from North Carolina State University have developed an efficient algorithm that can interpret the wheezing of patients with breathing difficulties to give medical providers information about what’s happening in the lungs.
Researchers Develop qPCR Prognosis Test for NSCLC Patients
A nine-gene molecular prognostic index (MPI) for patients with early-stage non-small cell lung cancer (NSCLC) was able to provide accurate survival stratification and could potentially inform the use of adjuvant therapy in patients struggling with the disease.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!