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Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital
M Alkhusheh, H Asalieh, N Smith

Following the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March.

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FDG PET/CT Utility in Gynecologic Malignancies: A comprehensive review of anatomy, pathways of metastatic spread and scan findings
Nicholas Plaxton, MD, Aruna Polsani, MD, Raghuveer Halkar, MD, Karen Godette, MD, Barron, Bruce, MD

Our objective was to review the five major gynaecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy.

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Saliva’s Diagnostic Potential
Vikender Yadav

Advantages and disadvantages of using saliva as a diagnostic source of information.

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A Systematic Review of Lifestyle Modification in Adults with Non-Alcoholic Fatty Liver Disease
C. Thoma, C. P. Day and M. I. Trenell, Newcastle University

This study reviews the causes of non-alcoholic fatty liver disease and the associated risk factor for type 2 diabetes and cardiovascular disease.

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Rapid PCR for Integration in Sample-to-answer Analysis Platforms
S. Brunklaus, T.E. Hansen-Hagge, J. Erwes, J. Höth, M. Jung, D. Latta, X. Strobach, C. Winkler, T. Röser, M. Ritzi-Lehnert, K.S. Drese

This poster describes how molecular testing at the point-of-care can increase time to results and yield rather specific information, concentrating on PCR on a chip layout which proves to be fast and robust.

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Identification of novel autoantigensin patients with liver autoimmune diseases by Protein MicroArray
C. Zingaretti1, M. Arigò1, A. Cardaci1, A. Sinisi1, L. Muratori3, P. Colombatto4, F. Bonino2, P. Invernizzi5, , A.L. Zignego6 MC. Crosti1, M. Moro1, J. Geginat1, Pagani M.1, R. De Francesco1, S. Abrignani1. & M. Bombaci1

The characterization of autoimmune disease-specific biomarkers are of primary importance for the development of diagnostic tools and the comprehension of pathogenetic mechanisms leading to autoimmunity. To this aim a protein microarray was employed to analyze serum samples from patients with autoimmune hepatitis (e.g. AIH & PBC) and of healthy as controls. A panel of autoantigens able to discriminate among the groups of patients was identified for potential use as biomarkers.

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MicroRNA expression in normal and malignant prostate tissues
Jessica Carlsson

In this study the aim was to identify a miRNA expression signature that could be used to separate between normal and malignant prostate tissues. Nine miRNAs were found to be differentially expressed and they could be used to separate between the normal and malignant tissues. A cross-validation procedure confirmed the generality of this expression signature, showing an accuracy of 85%.

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Point-of-Care Diagnostics for Sexually Transmitted Infections
Pascal Craw, Wamadeva Balachandran

This poster introduces the recently enlarged DoCLab research group at Brunel University, London. This large multidisciplinary group brings together electronic, mechanical and computer engineers with molecular biologists, biochemists and clinical collaborators to develop fully integrated, multiplex Point-Of-Care-Tests (POCT) for the self- diagnosis of infectious diseases.

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Optical Microchip Sensors for Multiplexed Detection of Biological Pathogens
D. Bhatta, A. Michel, M. Marti Villalba, G. D. Emmerson, I. J. G Sparrow, M. B. McDonnell, E. A. Perkins , R. W. Ely and G. A. Cartwright

SpectroSens, a multi-channel optical microchip sensor system suitable for rapid, label-free multiplexed detection of a wide range of bio-hazardous agents is presented. Optical chips containing multiple high-precision planar Bragg gratings are exploited as low-cost, robust refractive index sensors.

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SuNS microarray as novel biosensor for clinical diagnostics.
Pisanelli B., Dattilo D., Chetta M., Carducci F., De Ceglia G.

We here present an innovative microarray platform which aims to produce an higher standard of clinical microarray technology. The fabrication approach, involving a novel printing technology (Supramolecular Nano-Stamping) to reduce the production costs of the chips, together with a peculiar probe design, aiming to improve the assay sensitivity and workflow, intend to make the SuNS microarrays well poised to become an important element in the clinical diagnostics market.

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Showing Results 1 - 10 of 45
Scientific News
NIH Researchers Conduct First Genomic Survey of Human Skin Fungal Diversity
Location on the body surface determines fungal composition with the greatest diversity on feet.
App Helps Doctors, Students Learn to Diagnose Neurological Symptoms and Disease
The new app that presents a novel approach to learning the neurological physical exam, a challenging series of assessments aimed at diagnosing neurological disorders in patients.
Flu in Pregnancy May Quadruple Child’s Risk for Bipolar Disorder
NIH-funded study adds to evidence of overlap with Schizophrenia.
A Cautionary Tale on Genome-Sequencing Diagnostics for Rare Diseases
Studies in several children have raising new questions about inheritance, genomic sequencing, and diagnostic.
Mass Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer Biomarkers Using Tissue Culture
Rapid development of MS-based proteomic techniques in the last decade that has immensely helped researchers in candidate biomarker discovery.
Agilent Technologies Announces Winner of Fifth Annual Early Career Professor Award
Assistant Professor at Northwestern Recognized for Cancer Diagnostics Research.
Genetic Test Helps Predict Risk of Prostate Cancer Recurrence
Prostate cancer ranks as the most common internal malignancy diagnosed in men in the United States, but often does not require extensive treatment.
New Lung Cancer Guidelines Recommends Offering Screening to High-Risk Individuals
Advances in treatment have major impact on short- and long-term outcomes.
Genomic Analysis of Endometrial Tumors
Genomic classification of endometrial tumors could help guide treatment strategies, according to a new analysis.
Diagnostic Errors More Common, Costly and Harmful Than Treatment Mistakes
In reviewing 25 years of U.S. malpractice claim payouts, researchers found that diagnostic errors accounted for the largest fraction of claims, the most severe patient harm, and the highest total of penalty payouts.
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