Rapid, high-throughput, plate-based real-time PCR amplification and detection instrument.
The LightCycler® 1536 Instrument is a rapid, plate-based, thermal block cycler with integrated real-time, online detection capabilities. The architecture of this novel high-throughput platform is built upon the proven LightCycler® 480 Instrument with its high-performance optical unit and block cycler technologies. The LightCycler® 1536 optical unit facilitates mono- and dual-color assays using the dyes FAM, VIC/Yellow555, BrightGreen and others by supporting formats including Universal Probe Library (UPL) probes, hydrolysis probes, and intercalating dyes (e.g., BrightGreen). The unique thermal block cycler design in combination with the LightCycler® 1536 Multiwell Plate enables very high well-to-well homogeneity and inter-assay reproducibility. The LightCycler® 1536 Software supports the generation of real-time PCR results (e.g., Cp’s, endpoint fluorescence values), providing novel threshold functions for data refinement, and powerful tools for data sorting and reviewing. Since this system is designed for automated high-throughput laboratory workflows, the instrument’s software allows easy data management for network and LIMS environments. In combination with the RealTime ready reagents, representing the next generation of real-time PCR chemistry, the system offers a new surveillance concept that checks for pipetting errors.